| THE
UNIVERSITY OF HONG KONG |
DEPARTMENT OF CLINICAL ONCOLOGY
| Researcher : Au GKH |
| List of Research Outputs |
| Chua D.T.T., Sham J.S.T. and Au G.K.H., Concurrent Chemoirradiation with Cisplatin Followed by Adjuvant Chemotherapy with Ifosfamide, 5-Fluorouracil, and Leucovorin for Stage IV Nasopharyngeal Carcinoma, Head and Neck. USA, Wiley, 2004, 26: 118-126. |
| Chua D.T.T., Nicholls J.M., Sham J.S.T. and Au G.K.H., Prognostic Value of Epidermal Growth factor Receptor Expression in Patients with Advanced Stage Nasopharyngeal Carcinoma Treated with Induction Chemotherapy and Radiotherapy, International Journal of Radiation Oncology Biology Physcis. USA, Elsevier, 2004, 59: 11-20. |
| Chua D.T.T., Sham J.S.T., Leung L.H.T. and Au G.K.H., Prognostic value of tumor volume in early stage nasopahryngeal carcinoma treated by radiotherapy, Radiological Society of North America 89th Scientific Assembly and Annual Meeting. 2003. |
| Chua D.T.T., Sham J.S.T., Kwong D.L.W. and Au G.K.H., Treatment Outcome After Radiotherapy Alone For Patients With Stage I-II Nasopharyngeal Carcinoma, Cancer. 2003, 98: 74-80. |
| Chua D.T.T., Wei W.I., Sham J.S.T., Cheng C.K. and Au G.K.H., Treatment Outcome For Synchronous Loco-regional Failures Of Nasopharyngeal Carcinoma, Head And Neck. 2003, 25(7): 585-594. |
| Chua D.T.T., Sham J.S.T., Leung L...H...T..., Tai K.S. and Au G.K.H., Tumor Volume Is Not an Independent Prognostic factor in Early-Stage Nasopharyngeal Carcinoma Treated by Radiotherapy Alone , International Journal of Radiation Oncology Biology Physcis. USA, Elsevier, 2004, 58: 1437-1444. |
| Kwong D.L.W., Sham J.S.T., Au G.K.H., Chua D.T.T., Kwong P.W.K., Cheng C.K., Wu P.M., Law M.A.R.T.I.N. .W.M., Kwok C.H., Yau C.C., Wan K.Y., Chan T.T. and Choy D.T.K., Concurrent and Adjuvant Chemotherapy for Nasopharyngeal Carcinoma: A Factorial Study, Journal of Clinical Oncology. USA, American Society of Clinical Oncology, 2004, 22: 2643-2653. |
| Kwong D.L.W., Sham J.S.T., Au G.K.H., Chua D.T.T., Kwong P.W.K., Cheng C.K., Wu P.M., Law M.W.M., Kwok C.H., Yau C.C., Wan K.Y., Chan T.T. and Choy D.T.K., Concurrent and Adjuvant Chemotherapy for Nasopharyngeal Carcinoma:a Factorial Study, 39th Annual Meeting of American Society of Clinical Oncology, May 31-June 3, 2003, Chicago, IL. 2004. |
| Kwong D.L.W., Pow E.H.N., McMillan A.S., Sham J.S.T. and Au G.K.H., Intensity Modulated Radiotherapy for Early Stage Nasopharyngeal Carcinoma: Preliminary Results on Parotid Sparing, 45th Annual Meeting of the American Society for Therapeutic Radiology and Oncology,Octomber 19-23, Salt Lake City, US. 2003. |
| Researcher : Chan TT |
| List of Research Outputs |
| Kwong D.L.W., Sham J.S.T., Au G.K.H., Chua D.T.T., Kwong P.W.K., Cheng C.K., Wu P.M., Law M.A.R.T.I.N. .W.M., Kwok C.H., Yau C.C., Wan K.Y., Chan T.T. and Choy D.T.K., Concurrent and Adjuvant Chemotherapy for Nasopharyngeal Carcinoma: A Factorial Study, Journal of Clinical Oncology. USA, American Society of Clinical Oncology, 2004, 22: 2643-2653. |
| Kwong D.L.W., Sham J.S.T., Au G.K.H., Chua D.T.T., Kwong P.W.K., Cheng C.K., Wu P.M., Law M.W.M., Kwok C.H., Yau C.C., Wan K.Y., Chan T.T. and Choy D.T.K., Concurrent and Adjuvant Chemotherapy for Nasopharyngeal Carcinoma:a Factorial Study, 39th Annual Meeting of American Society of Clinical Oncology, May 31-June 3, 2003, Chicago, IL. 2004. |
| Researcher : Cheng CK |
| List of Research Outputs |
| Chua D.T.T., Wei W.I., Sham J.S.T., Cheng C.K. and Au G.K.H., Treatment Outcome For Synchronous Loco-regional Failures Of Nasopharyngeal Carcinoma, Head And Neck. 2003, 25(7): 585-594. |
| Kwong D.L.W., Sham J.S.T., Au G.K.H., Chua D.T.T., Kwong P.W.K., Cheng C.K., Wu P.M., Law M.A.R.T.I.N. .W.M., Kwok C.H., Yau C.C., Wan K.Y., Chan T.T. and Choy D.T.K., Concurrent and Adjuvant Chemotherapy for Nasopharyngeal Carcinoma: A Factorial Study, Journal of Clinical Oncology. USA, American Society of Clinical Oncology, 2004, 22: 2643-2653. |
| Kwong D.L.W., Sham J.S.T., Au G.K.H., Chua D.T.T., Kwong P.W.K., Cheng C.K., Wu P.M., Law M.W.M., Kwok C.H., Yau C.C., Wan K.Y., Chan T.T. and Choy D.T.K., Concurrent and Adjuvant Chemotherapy for Nasopharyngeal Carcinoma:a Factorial Study, 39th Annual Meeting of American Society of Clinical Oncology, May 31-June 3, 2003, Chicago, IL. 2004. |
| Researcher : Choy DTK |
| List of Research Outputs |
| Kwong D.L.W., Sham J.S.T., Au G.K.H., Chua D.T.T., Kwong P.W.K., Cheng C.K., Wu P.M., Law M.A.R.T.I.N. .W.M., Kwok C.H., Yau C.C., Wan K.Y., Chan T.T. and Choy D.T.K., Concurrent and Adjuvant Chemotherapy for Nasopharyngeal Carcinoma: A Factorial Study, Journal of Clinical Oncology. USA, American Society of Clinical Oncology, 2004, 22: 2643-2653. |
| Kwong D.L.W., Sham J.S.T., Au G.K.H., Chua D.T.T., Kwong P.W.K., Cheng C.K., Wu P.M., Law M.W.M., Kwok C.H., Yau C.C., Wan K.Y., Chan T.T. and Choy D.T.K., Concurrent and Adjuvant Chemotherapy for Nasopharyngeal Carcinoma:a Factorial Study, 39th Annual Meeting of American Society of Clinical Oncology, May 31-June 3, 2003, Chicago, IL. 2004. |
| Researcher : Chua DTT |
| Project Title: | A randomized trial comparing external reirradiation followed by radiosurgery boost versus external reirradiation alone in locally recurrent nasopharyngeal carcinoma |
| Investigator(s): | Dr. Chua D.T.T., Dr. Leung L.H.T., Prof. Sham J.S.T. |
| Department: | Clinical Oncology |
| Source(s) of Funding: | Hong Kong Research Grants Council Competitive Earmarked Research Grants |
| Start Date: | 11/2001 |
| Abstract: |
| To evaluate the impact of stereotactic radiosurgery (SRS) boost treatment on local control, survival and quality of life of patients with locally recurrent nasopharyngeal carcinoma (NPC) receiving external reirradiation. |
| Project Title: | Assessment of tumor regression during radiotherapy in nasopharyngeal carcinoma and correlation with local control |
| Investigator(s): | Dr. Chua D.T.T., Prof. Sham J.S.T. |
| Department: | Clinical Oncology |
| Source(s) of Funding: | Block Grant Earmarked for Research |
| Start Date: | 11/2001 |
| Completion Date: | 10/2003 |
| Abstract: |
| To assess the patterns of tumor regression during radiotherapy using quantitative measurement of changes in tumor volume by serial computed tomography imaging; to correlate the patterns of tumor regression during radiotherapy with subsequent local control. |
| List of Research Outputs |
| Chua D.T.T., Capecitabine monotherapy for recurrent and metastatic nasopharyngeal carcinoma, Second Roche Asia Oncology Forum. 2003. |
| Chua D.T.T., Sham J.S.T. and Au G.K.H., Concurrent Chemoirradiation with Cisplatin Followed by Adjuvant Chemotherapy with Ifosfamide, 5-Fluorouracil, and Leucovorin for Stage IV Nasopharyngeal Carcinoma, Head and Neck. USA, Wiley, 2004, 26: 118-126. |
| Chua D.T.T., Ma J. and Sham J.S.T., Long term surival after cisplatin-based induction chemotherapy and radiotherapy for nasopharyngeal carcinoma: A pooled data analysis of two Phase III trials, Proceedings of Fortieth Annual Meeting of American Society of Clinical Oncology. 2004, 23: 492. |
| Chua D.T.T., Nicholls J.M., Sham J.S.T. and Au G.K.H., Prognostic Value of Epidermal Growth factor Receptor Expression in Patients with Advanced Stage Nasopharyngeal Carcinoma Treated with Induction Chemotherapy and Radiotherapy, International Journal of Radiation Oncology Biology Physcis. USA, Elsevier, 2004, 59: 11-20. |
| Chua D.T.T., Sham J.S.T., Leung L.H.T. and Au G.K.H., Prognostic value of tumor volume in early stage nasopahryngeal carcinoma treated by radiotherapy, Radiological Society of North America 89th Scientific Assembly and Annual Meeting. 2003. |
| Chua D.T.T., Sham J.S.T., Kwong D.L.W. and Au G.K.H., Treatment Outcome After Radiotherapy Alone For Patients With Stage I-II Nasopharyngeal Carcinoma, Cancer. 2003, 98: 74-80. |
| Chua D.T.T., Wei W.I., Sham J.S.T., Cheng C.K. and Au G.K.H., Treatment Outcome For Synchronous Loco-regional Failures Of Nasopharyngeal Carcinoma, Head And Neck. 2003, 25(7): 585-594. |
| Chua D.T.T., Sham J.S.T., Leung L...H...T..., Tai K.S. and Au G.K.H., Tumor Volume Is Not an Independent Prognostic factor in Early-Stage Nasopharyngeal Carcinoma Treated by Radiotherapy Alone , International Journal of Radiation Oncology Biology Physcis. USA, Elsevier, 2004, 58: 1437-1444. |
| Kwong D.L.W., Sham J.S.T., Au G.K.H., Chua D.T.T., Kwong P.W.K., Cheng C.K., Wu P.M., Law M.A.R.T.I.N. .W.M., Kwok C.H., Yau C.C., Wan K.Y., Chan T.T. and Choy D.T.K., Concurrent and Adjuvant Chemotherapy for Nasopharyngeal Carcinoma: A Factorial Study, Journal of Clinical Oncology. USA, American Society of Clinical Oncology, 2004, 22: 2643-2653. |
| Kwong D.L.W., Sham J.S.T., Au G.K.H., Chua D.T.T., Kwong P.W.K., Cheng C.K., Wu P.M., Law M.W.M., Kwok C.H., Yau C.C., Wan K.Y., Chan T.T. and Choy D.T.K., Concurrent and Adjuvant Chemotherapy for Nasopharyngeal Carcinoma:a Factorial Study, 39th Annual Meeting of American Society of Clinical Oncology, May 31-June 3, 2003, Chicago, IL. 2004. |
| Lee A.W.M., Lau W.H., Tung S.Y., Chua D.T.T., Chappell R., Siu L., Chia S., Lau J. and Law C.K., Prospective randomized study on therapeutic gain achieved by addition of chemotherapy for T1-4N2-3 nasopharyngeal carcinoma (NPC), Fortieth Annual Meeting of American Society of Clinical Oncology. 2004. |
| Sham J.S.T., Kwong D.L.W. and Chua D.T.T., Radical Treatment Of Nasopharyngeal Carcinoma, Asia-Pacific. 2003, 1: 77-92. |
| Researcher : Fan Z |
| List of Research Outputs |
| Li Y.R., Wang L.D., Guan X.Y., Tsao G.S.W., Sham J.S.T., Fan Z., Yang C.S., Zheng S. and Kwong D.L.W., Comparative genomic hybridization of esophageal squamous cell carcinoma and gastric cardia adenocarcinoma from Linzhou, Henan, a high-incidenc area of esophageal cancer, Proceedings of the American Association for Cancer Research. 2003, 44: 897 no. 4520. |
| Researcher : Fung JMW |
| List of Research Outputs |
| Guan X.Y., Fung J.M.W., Ma N., Lau S.H., Tai L.S., Xie D., Zhang Y., Hu L., Wu Q.L., Fang Y. and Sham J.S.T., Oncogenic role of eIF-5A2 in the development of ovarian cancer., Cancer Research. 2004, 64: 4197-4200. |
| Researcher : Guan XY |
| Project Title: | Isolation of genes related to the pathogenesis of hepatocellular carcinoma and nasopharyngeal carcinoma: identification of the association between amplication of oncogenes and cancer prognosis |
| Investigator(s): | Dr. Guan X.Y. |
| Department: | Clinical Oncology |
| Source(s) of Funding: | PVC(R)'s China Collaboration Budget |
| Start Date: | 05/2001 |
| Abstract: |
| To study isolation of genes related to the pathogenesis of hepatocellular carcinoma and nasopharyngeal carcinoma: identification of the association between amplication of oncogenes and cancer prognosis. |
| Project Title: | Development of novel tools in the diagnosis and treatment of leukemia |
| Investigator(s): | Dr. Guan X.Y., Prof. Lu D.P., Prof. Sham J.S.T., Prof. Tong C.R. |
| Department: | Clinical Oncology |
| Source(s) of Funding: | National Natural Science Foundation of China |
| Start Date: | 12/2001 |
| Abstract: |
| To generate chromosome band-specific painting probes for all common breakpoints in ALL and acute myeloid leukemia (AML) by chromosome microdissection; to isolate at least one novel fusion gene from patients with acute leukemia; to use the fusion gene as DNA vaccine and its effect of activating anti-leukemia immune response in leukemia SCID-hu mice model will be detected. |
| Project Title: | Basic research for the mechanisms of development and progression of malignant tumors |
| Investigator(s): | Dr. Guan X.Y. |
| Department: | Clinical Oncology |
| Source(s) of Funding: | Technology / Research / Internal RAE |
| Start Date: | 03/2002 |
| Abstract: |
| To identify recurrent genomic alterations in 30 primary adenocarcinomas of lung and carcinomas using CGH technology; to establish gene expression profiles for lung cancer using cDNA microarray technique; to establish 10 pairs of xenografts of primary and their matched metastatic lung cancer by transplanting tumor cells into nude mice; to study the differences between primary and metastasis lung cancer with mentioned xenografts. |
| Project Title: | Characterization of roles of a new candidate oncogene eIF-5A2 in cancer development |
| Investigator(s): | Dr. Guan X.Y. |
| Department: | Clinical Oncology |
| Source(s) of Funding: | Hong Kong Research Grants Council Competitive Earmarked Research Grants |
| Start Date: | 10/2002 |
| Abstract: |
| The project is proposed to understand the tumorigenicity of the eIF-5A2 gene by in vitro assays (soft-agar assay and focus-formation assay) and in vivo approach (tumour formation in nude mouse). A broad survey using high-throughput tissue microarray will be employed to investigate the association of eIF-5A2 amplification and clinical features of various cancers by fluorescence in situ hybridization (FISH). |
| Project Title: | Identification of the mechanism of hepatitis B virus (HBV) integration in the development of hepatocellular carcinoma (HCC) |
| Investigator(s): | Dr. Guan X.Y. |
| Department: | Clinical Oncology |
| Source(s) of Funding: | Block Grant Earmarked for Research |
| Start Date: | 01/2003 |
| Abstract: |
| Although the integration of HBV has been associated with the development of HCC, the molecular mehanism remains unclear. It is believed that HBV and host factors (e.g. inflammatory/genetic factors) may contribute together to the process of HCC development. Although the association of HBV and HCC development has been widely studied, only a limited number of integrated HBV have been completely analyzed. Therefore, additional studies with more cases are needed to understand roles of HBV integrants involved in the HCC development. In order to obtain additional insight into the correlation of HBV integration and HCC development, integrated HBV in 10-20 HCC cases will be isolated and characterized by sequencing analysis. findings in this project may greatly facilitate the early diagnosis and prevention of HCC. |
| Project Title: | Isolation and characterization of oncogenes within a frequently amplified region at 19q13.1 in ovarian cancer |
| Investigator(s): | Dr. Guan X.Y. |
| Department: | Clinical Oncology |
| Source(s) of Funding: | RGC Projects (Block Grant Funded) |
| Start Date: | 07/2003 |
| Abstract: |
| To characterize the amplification of 19q13.1 in four ovarian cancer cell lines and to determine the overlapping MAR; to identify candidate oncogenes within the overlapping MAR; to investigate the association between the amplification of 19q13.1 and clinical features of ovarian cancer by tissue microarray; to study the tumorigenesity of SEI-1 gene; to characterize other candidate oncogenes within the overlapping MAR. |
| Project Title: | Characterization of oncogenic role of SEI-1 in the development of ovarian cancer |
| Investigator(s): | Dr. Guan X.Y. |
| Department: | Clinical Oncology |
| Source(s) of Funding: | Block Grant Earmarked for Research |
| Start Date: | 02/2004 |
| Abstract: |
| To study the tumorigenisity of SEI-1 using both in vitro and in vivo approaches; to define the clinical and pathological significance of the amplification of SEI-1 in ovarian cancer. |
| List of Research Outputs |
| Deng W., Tsao G.S.W., Guan X.Y. and Cheung A., The significance of dynamic dysfunction of critically short telomeres in directing the evolution of chromosomal structural instability in human cells undergoing immortalization, Proceedings of the American Association for Cancer Research. 2004, 45: 613-614 No. 2658. |
| Guan X.Y., Fung J.M.W., Ma N., Lau S.H., Tai L.S., Xie D., Zhang Y., Hu L., Wu Q.L., Fang Y. and Sham J.S.T., Oncogenic role of eIF-5A2 in the development of ovarian cancer., Cancer Research. 2004, 64: 4197-4200. |
| He Q.J., Zeng W.F., Sham J.S.T., Xie D., Yang X.W., Lin H.L., Zhan W.H., Lin F., Zeng S.D., Nie D., Ma L.F., Li C.J., Lu S. and Guan X.Y., Recurrent Genetic Alterations In 26 Colorectal Carcinomas And 21 Adenomas From Chinese Patients, Cancer Genet Cytogenet. 2003, 144: 112-118. |
| Hu L., Lau B.S.H., Tzang C.-.H., Wen J.M., Wang W., Huang M.H., Xie D., Wang Y., Wu M.C., Wu M.C., Huang J.F., Zeng W.F., Sham J.S.T., Yang M. and Guan X.Y., Association of Vimentin overexpression and hepatocellular carcinoma metastasis., Oncogene. 2004, 23: 298-302. |
| Hu L., Wen J.M., Sham J.S.T., Wang W., Xie D., Tjia W.M., Huang J.F., Zhang M., Zeng W.F. and Guan X.Y., Establishment of a pair of cell lines from a primary and its matched metastatic hepatocellular carcinoma tumors., Cancer Genetics and Cytogenetics. 2004, 148: 80-84. |
| Hu L., Hu L., Sham J.S.T., Tjia W.M., Tang Y.Q., Lu G.X. and Guan X.Y., Generation of a complete set of human telomeric-band painting probes by chromosome microdissection., Genomics. 2004, 83: 298-302. |
| Li Y.R., Wang L.D., Guan X.Y., Tsao G.S.W., Sham J.S.T., Fan Z., Yang C.S., Zheng S. and Kwong D.L.W., Comparative genomic hybridization of esophageal squamous cell carcinoma and gastric cardia adenocarcinoma from Linzhou, Henan, a high-incidenc area of esophageal cancer, Proceedings of the American Association for Cancer Research. 2003, 44: 897 no. 4520. |
| Tai L.S., Yan W.S., Fang Y., Xie D., Sham J.S.T. and Guan X.Y., Recurrent chromosomal imbalances in non small cell lung cancer: The association of 1q amplification and tumor recurrence., Cancer. 2004, 100: 1918-1927. |
| Tan Y., Hu L., Lin G., Sham J.S.T., Gong F., Guan X.Y. and Lu G., Genetic changes in human fetuses from spontaneous abortion after in vitro fertilization (IVF) detected by comparative genomic hybridization, Biological Reproduction. 2004, 70: 495-499. |
| Tang T.C.M., Poon R.T.P., Guan X.Y. and Fan S.T., The effect of cyclooxygenase-2 (COX-2) inhibitor, Celecoxib, on xenograft of hepatocellular carcinoma (HCC) in nude mice (Oral Presentation), AACR-NCI-EORTC International Conference on Molecular Targets and Cancer Therapeutics, Boston, U.S.A., 17-21 November 2003. |
| Tang T.C.M., Poon R.T.P., Guan X.Y. and Fan S.T., The effects of cyclooxygenase-2, Celecoxib, on xenografts of hepatocellular carcinoma in nude mice (Oral Presentation), The 8th Research Postgraduate Symposium, The University of Hong Kong, Hong Kong, 13 December 2003. |
| Wang T., Wang Y., Wu M.C., Guan X.Y. and Yin Z.F., Activating mechanism of transcriptor NF-kappaB regulated by hepatitis B virus X protein in hepatocellular carcinoma., World Journal of Gastroenterology. 2004, 10: 356-360. |
| Wang X., Guan X.Y., Tsao G.S.W., Cheung H.W., Lee D.T.W. and Wong Y.C., Identification of a novel function of TWIST, a bHLH protein, in the development of acquired taxol resistance in human cancer cells, Oncogene. 2004, 23: 474-482. |
| Wang X., Ling M.T., Guan X.Y., Tsao G.S.W., Cheung H.W., Lee D.T.W. and Wong Y.C., Identification of a novel function of TWIST, a bHLH protein, in the development of acquired taxol resistance in human cancer cells, Proceedings of the American Association for Cancer Research. 2004, 45: 142. |
| Wang Y., Lau B.S.H., Sham J.S.T., Wu M.C., Wang T. and Guan X.Y., Characterization of HBV integrants in 14 hepatocellular carcinomas: Association of truncated X gene and hepatocellular carcinogenesis., Oncogene. 2004, 23: 142-148. |
| Xie D., Zeng W.F., Sham J.S.T., Lin H.L., Che L.H., Fang Y., Wu H.X., Wu Q.L., He Q.-.J., Hu L. and Guan X.Y., Heterogenous Expressions and Associations of -Catenin, p16, E-cadeherin, and C-myc in Multistage Colorectal Carcinogenesis and Progression., International Journal Cancer. 2003, 107: 896-902. |
| Researcher : Hu L |
| List of Research Outputs |
| Guan X.Y., Fung J.M.W., Ma N., Lau S.H., Tai L.S., Xie D., Zhang Y., Hu L., Wu Q.L., Fang Y. and Sham J.S.T., Oncogenic role of eIF-5A2 in the development of ovarian cancer., Cancer Research. 2004, 64: 4197-4200. |
| Hu L., Lau B.S.H., Tzang C.-.H., Wen J.M., Wang W., Huang M.H., Xie D., Wang Y., Wu M.C., Wu M.C., Huang J.F., Zeng W.F., Sham J.S.T., Yang M. and Guan X.Y., Association of Vimentin overexpression and hepatocellular carcinoma metastasis., Oncogene. 2004, 23: 298-302. |
| Hu L., Wen J.M., Sham J.S.T., Wang W., Xie D., Tjia W.M., Huang J.F., Zhang M., Zeng W.F. and Guan X.Y., Establishment of a pair of cell lines from a primary and its matched metastatic hepatocellular carcinoma tumors., Cancer Genetics and Cytogenetics. 2004, 148: 80-84. |
| Hu L., Hu L., Sham J.S.T., Tjia W.M., Tang Y.Q., Lu G.X. and Guan X.Y., Generation of a complete set of human telomeric-band painting probes by chromosome microdissection., Genomics. 2004, 83: 298-302. |
| Tan Y., Hu L., Lin G., Sham J.S.T., Gong F., Guan X.Y. and Lu G., Genetic changes in human fetuses from spontaneous abortion after in vitro fertilization (IVF) detected by comparative genomic hybridization, Biological Reproduction. 2004, 70: 495-499. |
| Xie D., Zeng W.F., Sham J.S.T., Lin H.L., Che L.H., Fang Y., Wu H.X., Wu Q.L., He Q.-.J., Hu L. and Guan X.Y., Heterogenous Expressions and Associations of -Catenin, p16, E-cadeherin, and C-myc in Multistage Colorectal Carcinogenesis and Progression., International Journal Cancer. 2003, 107: 896-902. |
| Researcher : Kwok CH |
| List of Research Outputs |
| Kwong D.L.W., Sham J.S.T., Au G.K.H., Chua D.T.T., Kwong P.W.K., Cheng C.K., Wu P.M., Law M.A.R.T.I.N. .W.M., Kwok C.H., Yau C.C., Wan K.Y., Chan T.T. and Choy D.T.K., Concurrent and Adjuvant Chemotherapy for Nasopharyngeal Carcinoma: A Factorial Study, Journal of Clinical Oncology. USA, American Society of Clinical Oncology, 2004, 22: 2643-2653. |
| Kwong D.L.W., Sham J.S.T., Au G.K.H., Chua D.T.T., Kwong P.W.K., Cheng C.K., Wu P.M., Law M.W.M., Kwok C.H., Yau C.C., Wan K.Y., Chan T.T. and Choy D.T.K., Concurrent and Adjuvant Chemotherapy for Nasopharyngeal Carcinoma:a Factorial Study, 39th Annual Meeting of American Society of Clinical Oncology, May 31-June 3, 2003, Chicago, IL. 2004. |
| Researcher : Kwong DLW |
| Project Title: | A randomised controlled trial comparing intensity modulated radiotherapy with conventional radiotherapy in treatment of nasopharyngeal carcinoma |
| Investigator(s): | Dr. Kwong D.L.W., Prof. Lee P.W.H., Prof. McMillan A.S. |
| Department: | Clinical Oncology |
| Source(s) of Funding: | Block Grant Earmarked for Research |
| Start Date: | 02/2002 |
| Abstract: |
| To compare the efficacy of IMRT versus conventional radiotherapy in achieving loco-regional disease control and survival among patients with T2N0/N1 nasopharyngeal carcinoma; to study radiation complications for comparing the incidence and nature of complications for patients treated with IMRT versus conventional radiotherapy. |
| Project Title: | The use of intensity modulated radiotherapy in reduction of long term complications of radiotherapy among patients treated for early stage nasopharyngeal carcinoma |
| Investigator(s): | Dr. Kwong D.L.W., Prof. Lee P.W.H., Prof. McMillan A.S., Prof. Sham J.S.T. |
| Department: | Clinical Oncology |
| Source(s) of Funding: | RGC Projects (Block Grant Funded) |
| Start Date: | 07/2003 |
| Abstract: |
| To compare the efficacy of IMRT versus conventional radiotherapy in achieving loco-regional disease control and survival among patients with early, T1-2, No/N1 nasopharyngeal carcinoma; to carry out a prospective study on radiation complications to compare the incidence and nature of complications for patients treated with IMRT versus conventional radiotherapy. |
| List of Research Outputs |
| Chan G.C.F., Khong P.L., Kwong D.L.W., Chiang A.K.S., Hung K.N., Fan Y.W., Ha S.Y. and Lau Y.L., Outcome and long term neurological complications of childhood medulloblastoma: the QMH experience, Rehabilitation Scientific Conference 2003, Hong Kong West Cluster, Hong Kong, 25 October 2003. 28. |
| Chang H.W., Chan A., Kwong D.L.W., Wei W.I., Sham J.S.T. and Yuen P.W., Detection of hypermethylated RIZ1 gene in primary tumor, mouth, and throat rinising fluid, nasopharyngeal swab, and peripheral blood of nasopharyngeal carcinoma patient, Clinical Cancer Research . 2003, 9: 1033-1038. |
| Chang H.W., Chan A., Kwong D.L.W., Wei W.I., Sham J.S.T. and Yuen P.W., Evaluation of hypermethylated tumor suppressor genes as tumor marker in mouth and throat rinsing fluid, nasopharyngeal swab, peripheral blood of naospharyngeal carcinoma patients, International Journal of Cancer. 2003, 105(6): 851-855. |
| Chua D.T.T., Sham J.S.T., Kwong D.L.W. and Au G.K.H., Treatment Outcome After Radiotherapy Alone For Patients With Stage I-II Nasopharyngeal Carcinoma, Cancer. 2003, 98: 74-80. |
| Khong P.L., Leung L.H.T., Chan G.C.F., Kwong D.L.W., Cao G., Ooi C.G.C. and Chan F.L., Diffusion-tensor MR imaging in the evaluation of treatment induced neurotoxicity in medulloblastoma survivors. , 11th Annual Meeting of the International Society of Magnetic Resonance Imaging in Medicine (ISMRM), Toronto, Canada, 10-16 July 2003. (Proc Intl Soc Mag Reson Med 2003;11:537).. 2003. |
| Khong P.L., Leung L.H.T., Chan G.C.F., Kwong D.L.W., Guang C., Ooi C.G.C. and Leong Fung L.L.Y., Factors associated with loss of white matter anisotropy in post-treatment medulloblastoma survivors, ISMRM 12th Scientific Meeting, Kyoto, Japan, 15-21 May 2004. (Proc Intl Soc Mag Reson Med 2004;1249). 2004. |
| Khong P.L., Leung L.H.T., Chan G.C.F., Kwong D.L.W. and Ooi C.G.C., White-matter diffusion aniostropy after chemo-irradiation: a statistical parametric mapping (SPM) study and histogram analysis, The 4th Congress of Asian and Oceanic Society for Pediatric Radiology (AOSPR), Seoul, 24-26 Sept 2003. |
| Khong P.L., Leung L.H.T., Chan G.C.F., Kwong D.L.W. and Ooi C.G.C., White-matter diffusion anisotropy after chemoirradiation in medulloblastoma survivors: voxel-based analysis and histogram study, European Congress of Radiology, Vienna, Austria, 5-9 March 2004. |
| Kwong D.L.W., Advances in radiotherapy and chemotherapy for sarcomas, Head & Neck Course 2004. 2004. |
| Kwong D.L.W., Lam A., Guan X.Y., Law S.Y.K., Tai A., Wong J. and Sham J.S.T., Chromosomal aberrations in esophageal squamous cell carcinoma among Chinese: gain of 12p predicts poor prognosis after surgery, Human Pathology. 2004, 35(3): 309-316. |
| Kwong D.L.W., Sham J.S.T., Au G.K.H., Chua D.T.T., Kwong P.W.K., Cheng C.K., Wu P.M., Law M.A.R.T.I.N. .W.M., Kwok C.H., Yau C.C., Wan K.Y., Chan T.T. and Choy D.T.K., Concurrent and Adjuvant Chemotherapy for Nasopharyngeal Carcinoma: A Factorial Study, Journal of Clinical Oncology. USA, American Society of Clinical Oncology, 2004, 22: 2643-2653. |
| Kwong D.L.W., Sham J.S.T., Au G.K.H., Chua D.T.T., Kwong P.W.K., Cheng C.K., Wu P.M., Law M.W.M., Kwok C.H., Yau C.C., Wan K.Y., Chan T.T. and Choy D.T.K., Concurrent and Adjuvant Chemotherapy for Nasopharyngeal Carcinoma:a Factorial Study, 39th Annual Meeting of American Society of Clinical Oncology, May 31-June 3, 2003, Chicago, IL. 2004. |
| Kwong D.L.W., Pow E.H.N., McMillan A.S., Sham J.S.T. and Au G.K.H., Intensity Modulated Radiotherapy for Early Stage Nasopharyngeal Carcinoma: Preliminary Results on Parotid Sparing, 45th Annual Meeting of the American Society for Therapeutic Radiology and Oncology,Octomber 19-23, Salt Lake City, US. 2003. |
| Kwong D.L.W., Panelist in interactive session: congenital tumor, 10th Hong Kong International Concer Congress, 19-21/11/2003, Hong Kong. 2003. |
| Kwong D.L.W., Symposium on nasopharyngeal carcinoma: Concurrent chemotherapy using UFT, 10th Hong Kong International Cancer Congress, 19-21/11/2003, Hong Kong. 2003. |
| Law S.Y.K., Kwong D.L.W., Kwok K...F., Wong K...H., Chu K.M., Sham J.S.T. and Wong J., Improvement in treatment results and long-term survival of patients with esophageal cancer: impact of chemoradiation and change in treatment strategy, Annals of Surgery. 2003, 238(3): 339-348. |
| Law S.Y.K., Kwong D.L.W., Wong K.H., Kwok K.F., Sham J.S.T. and Wong J., Supra-carinal esophageal cancers have worse prognosis compared to more distally located tumors, preoperative chemoradiation results in better survival (Abstract), Diseases of the Esophagus . 2004, 17, Supplement 1: A43. |
| Leung L.H.T., Ooi C.G.C., Kwong D.L.W., Chan G.C.F., Cao G. and Khong P.L., White-matter diffusion anisotropy after chemo-irradiation: a statistical parametric mapping study and histogram analysis, NeuroImage. Elsevier, 2004, 21(1): 261-268. |
| Li Y.R., Wang L.D., Guan X.Y., Tsao G.S.W., Sham J.S.T., Fan Z., Yang C.S., Zheng S. and Kwong D.L.W., Comparative genomic hybridization of esophageal squamous cell carcinoma and gastric cardia adenocarcinoma from Linzhou, Henan, a high-incidenc area of esophageal cancer, Proceedings of the American Association for Cancer Research. 2003, 44: 897 no. 4520. |
| McMillan A.S., Pow E.H.N., Leung W.K., Wong M.C.M. and Kwong D.L.W., Oral health-related quality of life in southern Chinese following radiotherapy for nasopharyngeal carcinoma., Journal of Oral Rehabilitation . 2004, 31: 600-608. |
| Nicholls J.M., Hahn P., Kremmer E., FrÖhlich T., Arnold G.J., Sham J.S.T., Kwong D.L.W. and Grässer F.A., Detection of wild type and deleted latent membrane protein 1 (LMP1) of Epstein-Barr virus in clinical biopsy material, Journal of Virological Methods. 2004, 116(1): 79-88. |
| Pow E.H.N., McMillan A.S., Leung W.K., Wong M.C.M. and Kwong D.L.W., Saliva changes 1-year after intensity-modulated/conventional radiotherapy for nasopharyngeal carcinoma, Journal of Dental Research. 2004-03-09, 2004, 83 (Spec Iss A): 2229. |
| Pow E.H.N., McMillan A.S., Leung W.K., Wong M.C.M. and Kwong D.L.W., Salivary gland function and xerostomia in southern Chinese following radiotherapy for nasopharyngeal carcinoma, Clinical Oral Investigations. 2003, 7(4): 230-234. |
| Sham J.S.T., Kwong D.L.W. and Chua D.T.T., Radical Treatment Of Nasopharyngeal Carcinoma, Asia-Pacific. 2003, 1: 77-92. |
| Wong T.S., Kwong D.L.W., Sham J.S.T., Wei W.I., Kwong Y.L. and Yuen P.W., Clinicopathologic significance of plasma matrix metalloproteinase-2 and -9 levels in patients with undifferentiated nasopharyngeal carcinoma, European Journal of Surgical Oncology. 2004, 30(5): 560-564. |
| Wong T.S., Kwong D.L.W., Sham J.S.T., Tsao G.S.W., Wei W.I., Kwong Y.L. and Yuen P.W., Promoter Hypermethylation Of High-in-normal 1 Gene In Primary Nasopharyngeal Carcinoma, Clinical Cancer Research. 2003, 9: 3042-3046. |
| Wong T.S., Kwong D.L.W., Sham J.S.T., Wei W.I., Kwong Y.L. and Yuen P.W., Quantitative plasma hypermethylated DNA markers of undifferentiated nasopharyngeal carcinoma, Clinical Cancer Research. 2004, 10(7): 2401-2406. |
| Wu W.C.V., Sham J.S.T. and Kwong D.L.W., A dosimetric comparison between traditionally planned and inverse planned radiation therapy of non-small cell lung cancer, The Radiographers . 2003, 50 (3): 147-152. |
| Wu W.C.V., Kwong D.L.W., Sham J.S.T. and Mui A.W.L., Auto-optimisation for three-dimensional conformal radiotherapy of nasopharyngeal carcinoma, Radiography. 2003, 9: 201-210. |
| Wu W.C.V., Sham J.S.T. and Kwong D.L.W., Evaluation of conformity index in conformal radiotherapy of nasopharyngeal carcinoma, The Hong Kong Radiographers Journal. . 2004, Volume 7, No 2: 11-14. |
| Wu W.C.V., Kwong D.L.W. and Sham J.S.T., Target dose conformity in 3-dimensional conformal radiotherapy and internsity modulated radiotherapy , Radiother Oncol.. 2004, 71: 201-6. |
| Researcher : Kwong PWK |
| List of Research Outputs |
| Kwong D.L.W., Sham J.S.T., Au G.K.H., Chua D.T.T., Kwong P.W.K., Cheng C.K., Wu P.M., Law M.A.R.T.I.N. .W.M., Kwok C.H., Yau C.C., Wan K.Y., Chan T.T. and Choy D.T.K., Concurrent and Adjuvant Chemotherapy for Nasopharyngeal Carcinoma: A Factorial Study, Journal of Clinical Oncology. USA, American Society of Clinical Oncology, 2004, 22: 2643-2653. |
| Kwong D.L.W., Sham J.S.T., Au G.K.H., Chua D.T.T., Kwong P.W.K., Cheng C.K., Wu P.M., Law M.W.M., Kwok C.H., Yau C.C., Wan K.Y., Chan T.T. and Choy D.T.K., Concurrent and Adjuvant Chemotherapy for Nasopharyngeal Carcinoma:a Factorial Study, 39th Annual Meeting of American Society of Clinical Oncology, May 31-June 3, 2003, Chicago, IL. 2004. |
| Researcher : Lau BSH |
| List of Research Outputs |
| Hu L., Lau B.S.H., Tzang C.-.H., Wen J.M., Wang W., Huang M.H., Xie D., Wang Y., Wu M.C., Wu M.C., Huang J.F., Zeng W.F., Sham J.S.T., Yang M. and Guan X.Y., Association of Vimentin overexpression and hepatocellular carcinoma metastasis., Oncogene. 2004, 23: 298-302. |
| Wang Y., Lau B.S.H., Sham J.S.T., Wu M.C., Wang T. and Guan X.Y., Characterization of HBV integrants in 14 hepatocellular carcinomas: Association of truncated X gene and hepatocellular carcinogenesis., Oncogene. 2004, 23: 142-148. |
| Researcher : Lau SH |
| List of Research Outputs |
| Guan X.Y., Fung J.M.W., Ma N., Lau S.H., Tai L.S., Xie D., Zhang Y., Hu L., Wu Q.L., Fang Y. and Sham J.S.T., Oncogenic role of eIF-5A2 in the development of ovarian cancer., Cancer Research. 2004, 64: 4197-4200. |
| Researcher : Lau WH |
| List of Research Outputs |
| Lee A.W.M., Lau W.H., Tung S.Y., Chua D.T.T., Chappell R., Siu L., Chia S., Lau J. and Law C.K., Prospective randomized study on therapeutic gain achieved by addition of chemotherapy for T1-4N2-3 nasopharyngeal carcinoma (NPC), Fortieth Annual Meeting of American Society of Clinical Oncology. 2004. |
| Researcher : Law CK |
| List of Research Outputs |
| Lee A.W.M., Lau W.H., Tung S.Y., Chua D.T.T., Chappell R., Siu L., Chia S., Lau J. and Law C.K., Prospective randomized study on therapeutic gain achieved by addition of chemotherapy for T1-4N2-3 nasopharyngeal carcinoma (NPC), Fortieth Annual Meeting of American Society of Clinical Oncology. 2004. |
| Researcher : Lee AWM |
| List of Research Outputs |
| Lee A.W.M., Lau W.H., Tung S.Y., Chua D.T.T., Chappell R., Siu L., Chia S., Lau J. and Law C.K., Prospective randomized study on therapeutic gain achieved by addition of chemotherapy for T1-4N2-3 nasopharyngeal carcinoma (NPC), Fortieth Annual Meeting of American Society of Clinical Oncology. 2004. |
| Researcher : Ma N |
| List of Research Outputs |
| Guan X.Y., Fung J.M.W., Ma N., Lau S.H., Tai L.S., Xie D., Zhang Y., Hu L., Wu Q.L., Fang Y. and Sham J.S.T., Oncogenic role of eIF-5A2 in the development of ovarian cancer., Cancer Research. 2004, 64: 4197-4200. |
| Researcher : Ngan KC |
| List of Research Outputs |
| Lau G., Yiu H.H.Y., Fong D.Y.T., Cheng H.C., Au W.Y., Lai L.S.F., Cheung M., Zhang H.Y., Lie A.K.W., Ngan K.C. and Liang R.H.S., Early Is Superior to Deferred Preemptive Lamivudine Therapy for Hepatitis B Patients Undergoing Chemotherapy, Gastroenterology. 2003, 125: 1742-1749. |
| Researcher : Sham JST |
| List of Research Outputs |
| Chang H.W., Chan A., Kwong D.L.W., Wei W.I., Sham J.S.T. and Yuen P.W., Detection of hypermethylated RIZ1 gene in primary tumor, mouth, and throat rinising fluid, nasopharyngeal swab, and peripheral blood of nasopharyngeal carcinoma patient, Clinical Cancer Research . 2003, 9: 1033-1038. |
| Chow L.W.C., Loo T.Y., Sham J.S.T. and Cheung M.N.B., Radix bupleuri containing compound (KY88 Liver-Livo) induces apoptosis and production of interleukin-4 and tumor necrosis factor-a in liver cancer cells in-vitro, American Journal of Chinese Medicine. 2004, 32(2): 185-193. |
| Chua D.T.T., Sham J.S.T. and Au G.K.H., Concurrent Chemoirradiation with Cisplatin Followed by Adjuvant Chemotherapy with Ifosfamide, 5-Fluorouracil, and Leucovorin for Stage IV Nasopharyngeal Carcinoma, Head and Neck. USA, Wiley, 2004, 26: 118-126. |
| Chua D.T.T., Ma J. and Sham J.S.T., Long term surival after cisplatin-based induction chemotherapy and radiotherapy for nasopharyngeal carcinoma: A pooled data analysis of two Phase III trials, Proceedings of Fortieth Annual Meeting of American Society of Clinical Oncology. 2004, 23: 492. |
| Chua D.T.T., Nicholls J.M., Sham J.S.T. and Au G.K.H., Prognostic Value of Epidermal Growth factor Receptor Expression in Patients with Advanced Stage Nasopharyngeal Carcinoma Treated with Induction Chemotherapy and Radiotherapy, International Journal of Radiation Oncology Biology Physcis. USA, Elsevier, 2004, 59: 11-20. |
| Chua D.T.T., Sham J.S.T., Leung L.H.T. and Au G.K.H., Prognostic value of tumor volume in early stage nasopahryngeal carcinoma treated by radiotherapy, Radiological Society of North America 89th Scientific Assembly and Annual Meeting. 2003. |
| Chua D.T.T., Sham J.S.T., Kwong D.L.W. and Au G.K.H., Treatment Outcome After Radiotherapy Alone For Patients With Stage I-II Nasopharyngeal Carcinoma, Cancer. 2003, 98: 74-80. |
| Chua D.T.T., Wei W.I., Sham J.S.T., Cheng C.K. and Au G.K.H., Treatment Outcome For Synchronous Loco-regional Failures Of Nasopharyngeal Carcinoma, Head And Neck. 2003, 25(7): 585-594. |
| Chua D.T.T., Sham J.S.T., Leung L...H...T..., Tai K.S. and Au G.K.H., Tumor Volume Is Not an Independent Prognostic factor in Early-Stage Nasopharyngeal Carcinoma Treated by Radiotherapy Alone , International Journal of Radiation Oncology Biology Physcis. USA, Elsevier, 2004, 58: 1437-1444. |
| Guan X.Y., Fung J.M.W., Ma N., Lau S.H., Tai L.S., Xie D., Zhang Y., Hu L., Wu Q.L., Fang Y. and Sham J.S.T., Oncogenic role of eIF-5A2 in the development of ovarian cancer., Cancer Research. 2004, 64: 4197-4200. |
| He Q.J., Zeng W.F., Sham J.S.T., Xie D., Yang X.W., Lin H.L., Zhan W.H., Lin F., Zeng S.D., Nie D., Ma L.F., Li C.J., Lu S. and Guan X.Y., Recurrent Genetic Alterations In 26 Colorectal Carcinomas And 21 Adenomas From Chinese Patients, Cancer Genet Cytogenet. 2003, 144: 112-118. |
| Hu L., Lau B.S.H., Tzang C.-.H., Wen J.M., Wang W., Huang M.H., Xie D., Wang Y., Wu M.C., Wu M.C., Huang J.F., Zeng W.F., Sham J.S.T., Yang M. and Guan X.Y., Association of Vimentin overexpression and hepatocellular carcinoma metastasis., Oncogene. 2004, 23: 298-302. |
| Hu L., Wen J.M., Sham J.S.T., Wang W., Xie D., Tjia W.M., Huang J.F., Zhang M., Zeng W.F. and Guan X.Y., Establishment of a pair of cell lines from a primary and its matched metastatic hepatocellular carcinoma tumors., Cancer Genetics and Cytogenetics. 2004, 148: 80-84. |
| Hu L., Hu L., Sham J.S.T., Tjia W.M., Tang Y.Q., Lu G.X. and Guan X.Y., Generation of a complete set of human telomeric-band painting probes by chromosome microdissection., Genomics. 2004, 83: 298-302. |
| Kwong D.L.W., Lam A., Guan X.Y., Law S.Y.K., Tai A., Wong J. and Sham J.S.T., Chromosomal aberrations in esophageal squamous cell carcinoma among Chinese: gain of 12p predicts poor prognosis after surgery, Human Pathology. 2004, 35(3): 309-316. |
| Kwong D.L.W., Sham J.S.T., Au G.K.H., Chua D.T.T., Kwong P.W.K., Cheng C.K., Wu P.M., Law M.A.R.T.I.N. .W.M., Kwok C.H., Yau C.C., Wan K.Y., Chan T.T. and Choy D.T.K., Concurrent and Adjuvant Chemotherapy for Nasopharyngeal Carcinoma: A Factorial Study, Journal of Clinical Oncology. USA, American Society of Clinical Oncology, 2004, 22: 2643-2653. |
| Kwong D.L.W., Sham J.S.T., Au G.K.H., Chua D.T.T., Kwong P.W.K., Cheng C.K., Wu P.M., Law M.W.M., Kwok C.H., Yau C.C., Wan K.Y., Chan T.T. and Choy D.T.K., Concurrent and Adjuvant Chemotherapy for Nasopharyngeal Carcinoma:a Factorial Study, 39th Annual Meeting of American Society of Clinical Oncology, May 31-June 3, 2003, Chicago, IL. 2004. |
| Kwong D.L.W., Pow E.H.N., McMillan A.S., Sham J.S.T. and Au G.K.H., Intensity Modulated Radiotherapy for Early Stage Nasopharyngeal Carcinoma: Preliminary Results on Parotid Sparing, 45th Annual Meeting of the American Society for Therapeutic Radiology and Oncology,Octomber 19-23, Salt Lake City, US. 2003. |
| Law S.Y.K., Kwong D.L.W., Kwok K...F., Wong K...H., Chu K.M., Sham J.S.T. and Wong J., Improvement in treatment results and long-term survival of patients with esophageal cancer: impact of chemoradiation and change in treatment strategy, Annals of Surgery. 2003, 238(3): 339-348. |
| Law S.Y.K., Kwong D.L.W., Wong K.H., Kwok K.F., Sham J.S.T. and Wong J., Supra-carinal esophageal cancers have worse prognosis compared to more distally located tumors, preoperative chemoradiation results in better survival (Abstract), Diseases of the Esophagus . 2004, 17, Supplement 1: A43. |
| Li Y.R., Wang L.D., Guan X.Y., Tsao G.S.W., Sham J.S.T., Fan Z., Yang C.S., Zheng S. and Kwong D.L.W., Comparative genomic hybridization of esophageal squamous cell carcinoma and gastric cardia adenocarcinoma from Linzhou, Henan, a high-incidenc area of esophageal cancer, Proceedings of the American Association for Cancer Research. 2003, 44: 897 no. 4520. |
| Lin W.M., Yuan X., Yuen P.W., Wei W.I., Sham J.S.T., Shi P.C. and Qu J., Classification of in vivo autofluorescence spectra using support vector machines, Journal of Biomedical Optics. 2004, 9(1): 180-186. |
| Nicholls J.M., Hahn P., Kremmer E., FrÖhlich T., Arnold G.J., Sham J.S.T., Kwong D.L.W. and Grässer F.A., Detection of wild type and deleted latent membrane protein 1 (LMP1) of Epstein-Barr virus in clinical biopsy material, Journal of Virological Methods. 2004, 116(1): 79-88. |
| Sham J.S.T., Kwong D.L.W. and Chua D.T.T., Radical Treatment Of Nasopharyngeal Carcinoma, Asia-Pacific. 2003, 1: 77-92. |
| Tai L.S., Yan W.S., Fang Y., Xie D., Sham J.S.T. and Guan X.Y., Recurrent chromosomal imbalances in non small cell lung cancer: The association of 1q amplification and tumor recurrence., Cancer. 2004, 100: 1918-1927. |
| Tan Y., Hu L., Lin G., Sham J.S.T., Gong F., Guan X.Y. and Lu G., Genetic changes in human fetuses from spontaneous abortion after in vitro fertilization (IVF) detected by comparative genomic hybridization, Biological Reproduction. 2004, 70: 495-499. |
| Wang Y., Lau B.S.H., Sham J.S.T., Wu M.C., Wang T. and Guan X.Y., Characterization of HBV integrants in 14 hepatocellular carcinomas: Association of truncated X gene and hepatocellular carcinogenesis., Oncogene. 2004, 23: 142-148. |
| Wei W.I. and Sham J.S.T., Cancer of the nasopharynx, In: Myers E, Suen J, Myers J and Hann E, Cancer of the Head & Neck. W.B. Saunders Company, 2003, 229-250. |
| Wong T.S., Kwong D.L.W., Sham J.S.T., Wei W.I., Kwong Y.L. and Yuen P.W., Clinicopathologic significance of plasma matrix metalloproteinase-2 and -9 levels in patients with undifferentiated nasopharyngeal carcinoma, European Journal of Surgical Oncology. 2004, 30(5): 560-564. |
| Wong T.S., Kwong D.L.W., Sham J.S.T., Tsao G.S.W., Wei W.I., Kwong Y.L. and Yuen P.W., Promoter Hypermethylation Of High-in-normal 1 Gene In Primary Nasopharyngeal Carcinoma, Clinical Cancer Research. 2003, 9: 3042-3046. |
| Wong T.S., Kwong D.L.W., Sham J.S.T., Wei W.I., Kwong Y.L. and Yuen P.W., Quantitative plasma hypermethylated DNA markers of undifferentiated nasopharyngeal carcinoma, Clinical Cancer Research. 2004, 10(7): 2401-2406. |
| Wu W.C.V., Sham J.S.T. and Kwong D.L.W., A dosimetric comparison between traditionally planned and inverse planned radiation therapy of non-small cell lung cancer, The Radiographers . 2003, 50 (3): 147-152. |
| Wu W.C.V., Kwong D.L.W., Sham J.S.T. and Mui A.W.L., Auto-optimisation for three-dimensional conformal radiotherapy of nasopharyngeal carcinoma, Radiography. 2003, 9: 201-210. |
| Wu W.C.V., Sham J.S.T. and Kwong D.L.W., Evaluation of conformity index in conformal radiotherapy of nasopharyngeal carcinoma, The Hong Kong Radiographers Journal. . 2004, Volume 7, No 2: 11-14. |
| Wu W.C.V., Kwong D.L.W. and Sham J.S.T., Target dose conformity in 3-dimensional conformal radiotherapy and internsity modulated radiotherapy , Radiother Oncol.. 2004, 71: 201-6. |
| Xie D., Zeng W.F., Sham J.S.T., Lin H.L., Che L.H., Fang Y., Wu H.X., Wu Q.L., He Q.-.J., Hu L. and Guan X.Y., Heterogenous Expressions and Associations of -Catenin, p16, E-cadeherin, and C-myc in Multistage Colorectal Carcinogenesis and Progression., International Journal Cancer. 2003, 107: 896-902. |
| Researcher : Tai LS |
| List of Research Outputs |
| Guan X.Y., Fung J.M.W., Ma N., Lau S.H., Tai L.S., Xie D., Zhang Y., Hu L., Wu Q.L., Fang Y. and Sham J.S.T., Oncogenic role of eIF-5A2 in the development of ovarian cancer., Cancer Research. 2004, 64: 4197-4200. |
| Tai L.S., Yan W.S., Fang Y., Xie D., Sham J.S.T. and Guan X.Y., Recurrent chromosomal imbalances in non small cell lung cancer: The association of 1q amplification and tumor recurrence., Cancer. 2004, 100: 1918-1927. |
| Researcher : Tan Y |
| List of Research Outputs |
| Tan Y., Hu L., Lin G., Sham J.S.T., Gong F., Guan X.Y. and Lu G., Genetic changes in human fetuses from spontaneous abortion after in vitro fertilization (IVF) detected by comparative genomic hybridization, Biological Reproduction. 2004, 70: 495-499. |
| Researcher : Tjia WM |
| List of Research Outputs |
| Hu L., Wen J.M., Sham J.S.T., Wang W., Xie D., Tjia W.M., Huang J.F., Zhang M., Zeng W.F. and Guan X.Y., Establishment of a pair of cell lines from a primary and its matched metastatic hepatocellular carcinoma tumors., Cancer Genetics and Cytogenetics. 2004, 148: 80-84. |
| Hu L., Hu L., Sham J.S.T., Tjia W.M., Tang Y.Q., Lu G.X. and Guan X.Y., Generation of a complete set of human telomeric-band painting probes by chromosome microdissection., Genomics. 2004, 83: 298-302. |
| Researcher : Wang Y |
| List of Research Outputs |
| Hu L., Lau B.S.H., Tzang C.-.H., Wen J.M., Wang W., Huang M.H., Xie D., Wang Y., Wu M.C., Wu M.C., Huang J.F., Zeng W.F., Sham J.S.T., Yang M. and Guan X.Y., Association of Vimentin overexpression and hepatocellular carcinoma metastasis., Oncogene. 2004, 23: 298-302. |
| Wang T., Wang Y., Wu M.C., Guan X.Y. and Yin Z.F., Activating mechanism of transcriptor NF-kappaB regulated by hepatitis B virus X protein in hepatocellular carcinoma., World Journal of Gastroenterology. 2004, 10: 356-360. |
| Wang Y., Lau B.S.H., Sham J.S.T., Wu M.C., Wang T. and Guan X.Y., Characterization of HBV integrants in 14 hepatocellular carcinomas: Association of truncated X gene and hepatocellular carcinogenesis., Oncogene. 2004, 23: 142-148. |
| Researcher : Wu PM |
| List of Research Outputs |
| Kwong D.L.W., Sham J.S.T., Au G.K.H., Chua D.T.T., Kwong P.W.K., Cheng C.K., Wu P.M., Law M.A.R.T.I.N. .W.M., Kwok C.H., Yau C.C., Wan K.Y., Chan T.T. and Choy D.T.K., Concurrent and Adjuvant Chemotherapy for Nasopharyngeal Carcinoma: A Factorial Study, Journal of Clinical Oncology. USA, American Society of Clinical Oncology, 2004, 22: 2643-2653. |
| Kwong D.L.W., Sham J.S.T., Au G.K.H., Chua D.T.T., Kwong P.W.K., Cheng C.K., Wu P.M., Law M.W.M., Kwok C.H., Yau C.C., Wan K.Y., Chan T.T. and Choy D.T.K., Concurrent and Adjuvant Chemotherapy for Nasopharyngeal Carcinoma:a Factorial Study, 39th Annual Meeting of American Society of Clinical Oncology, May 31-June 3, 2003, Chicago, IL. 2004. |
| Researcher : Wu WCV |
| List of Research Outputs |
| Wu W.C.V., Sham J.S.T. and Kwong D.L.W., A dosimetric comparison between traditionally planned and inverse planned radiation therapy of non-small cell lung cancer, The Radiographers . 2003, 50 (3): 147-152. |
| Wu W.C.V., Kwong D.L.W., Sham J.S.T. and Mui A.W.L., Auto-optimisation for three-dimensional conformal radiotherapy of nasopharyngeal carcinoma, Radiography. 2003, 9: 201-210. |
| Wu W.C.V., Sham J.S.T. and Kwong D.L.W., Evaluation of conformity index in conformal radiotherapy of nasopharyngeal carcinoma, The Hong Kong Radiographers Journal. . 2004, Volume 7, No 2: 11-14. |
| Wu W.C.V., Kwong D.L.W. and Sham J.S.T., Target dose conformity in 3-dimensional conformal radiotherapy and internsity modulated radiotherapy , Radiother Oncol.. 2004, 71: 201-6. |
| Researcher : Xie D |
| List of Research Outputs |
| Guan X.Y., Fung J.M.W., Ma N., Lau S.H., Tai L.S., Xie D., Zhang Y., Hu L., Wu Q.L., Fang Y. and Sham J.S.T., Oncogenic role of eIF-5A2 in the development of ovarian cancer., Cancer Research. 2004, 64: 4197-4200. |
| He Q.J., Zeng W.F., Sham J.S.T., Xie D., Yang X.W., Lin H.L., Zhan W.H., Lin F., Zeng S.D., Nie D., Ma L.F., Li C.J., Lu S. and Guan X.Y., Recurrent Genetic Alterations In 26 Colorectal Carcinomas And 21 Adenomas From Chinese Patients, Cancer Genet Cytogenet. 2003, 144: 112-118. |
| Hu L., Lau B.S.H., Tzang C.-.H., Wen J.M., Wang W., Huang M.H., Xie D., Wang Y., Wu M.C., Wu M.C., Huang J.F., Zeng W.F., Sham J.S.T., Yang M. and Guan X.Y., Association of Vimentin overexpression and hepatocellular carcinoma metastasis., Oncogene. 2004, 23: 298-302. |
| Hu L., Wen J.M., Sham J.S.T., Wang W., Xie D., Tjia W.M., Huang J.F., Zhang M., Zeng W.F. and Guan X.Y., Establishment of a pair of cell lines from a primary and its matched metastatic hepatocellular carcinoma tumors., Cancer Genetics and Cytogenetics. 2004, 148: 80-84. |
| Tai L.S., Yan W.S., Fang Y., Xie D., Sham J.S.T. and Guan X.Y., Recurrent chromosomal imbalances in non small cell lung cancer: The association of 1q amplification and tumor recurrence., Cancer. 2004, 100: 1918-1927. |
| Xie D., Zeng W.F., Sham J.S.T., Lin H.L., Che L.H., Fang Y., Wu H.X., Wu Q.L., He Q.-.J., Hu L. and Guan X.Y., Heterogenous Expressions and Associations of -Catenin, p16, E-cadeherin, and C-myc in Multistage Colorectal Carcinogenesis and Progression., International Journal Cancer. 2003, 107: 896-902. |
| Researcher : Yau CC |
| List of Research Outputs |
| Kwong D.L.W., Sham J.S.T., Au G.K.H., Chua D.T.T., Kwong P.W.K., Cheng C.K., Wu P.M., Law M.A.R.T.I.N. .W.M., Kwok C.H., Yau C.C., Wan K.Y., Chan T.T. and Choy D.T.K., Concurrent and Adjuvant Chemotherapy for Nasopharyngeal Carcinoma: A Factorial Study, Journal of Clinical Oncology. USA, American Society of Clinical Oncology, 2004, 22: 2643-2653. |
| Kwong D.L.W., Sham J.S.T., Au G.K.H., Chua D.T.T., Kwong P.W.K., Cheng C.K., Wu P.M., Law M.W.M., Kwok C.H., Yau C.C., Wan K.Y., Chan T.T. and Choy D.T.K., Concurrent and Adjuvant Chemotherapy for Nasopharyngeal Carcinoma:a Factorial Study, 39th Annual Meeting of American Society of Clinical Oncology, May 31-June 3, 2003, Chicago, IL. 2004. |
| Researcher : Zhang Y |
| List of Research Outputs |
| Guan X.Y., Fung J.M.W., Ma N., Lau S.H., Tai L.S., Xie D., Zhang Y., Hu L., Wu Q.L., Fang Y. and Sham J.S.T., Oncogenic role of eIF-5A2 in the development of ovarian cancer., Cancer Research. 2004, 64: 4197-4200. |