DEPARTMENT OF SURGERY
| Researcher : Au DKK |
| Project Title: | Electrical tinnitus suppression in hearing-impaired patients |
| Investigator(s): | Au DKK, Ho WK |
| Department: | Surgery |
| Source(s) of Funding: | Small Project Funding |
| Start Date: | 11/2003 |
| Abstract: |
| To evaluate the effectiveness of electrical tinnitus suppression in patients with sensorineural hearing loss; to compare the effectiveness of high versus low electrical stimulation rate in tinnitus suppression. |
| List of Research Outputs |
| Au D.K.K., Advances in cochlear implant (Invited Speaker), The First People's Hospital of Foshan, PR China, 4 September. 2004. |
| Au D.K.K., Analogue vs digital aids, hearing amplifications: what's new? (Invited), The Philippine Society of Otolaryngology - Head and Neck Surgery, Inc. 48th PSO-HNS Annual Convention, The Philippines, 30 November - 3 December 2004. |
| Au D.K.K., Audiologist's role in BAHA (Invited), Thai Speech-Language & Hearing Association Annual Convention, Thailand, 16 December 2004. |
| Au D.K.K., Hui Y., Chow C.K. and Wei W.I., 香港失聰幼兒早期人工耳蝸植入後的聽力和言語康復, Chinese Scientific Journal of Hearing and Speech Rehabilitation. 2004, 6: 14-16. |
| Au D.K.K., Co-opt Member of Medical Committee (1998 - present), Occupational Deafness Compensation Board. 2005. |
| Au D.K.K., Cochlear implant for hearing impaired children (Invited), Pamela Youde Nethersole Eastern Hospital Education Program for Medical and Paramedical Professional Working with Handicapped Children, Hong Kong, 26 May 2005. 2005. |
| Au D.K.K., Chu K.M.Y., Chow C.K., Hui Y. and Wei W.I., Cognitive abilities of patients with cochlear implant in the discrimination of tone stimuli with minimal contrast, Cochlear Implant International, The Proceedings of the Fourth Asian-Pacific Symposium on Cochlear Implant and Related Sciences, Taipei, Taiwan, 2003. 2004, 5 (Suppl. 1): 179-181. |
| Au D.K.K., Experience in cochlear implant at Queen Mary Hospital, University of Hong Kong Medical Centre (Invited), Thai Speech-Language & Hearing Association Annual Convention, Thailand, 16 December 2004. |
| Au D.K.K., How to choose a hearing aid? (Invited), Occupational Deafness Compensation Board, Hong Kong, 8 January 2005. 2005. |
| Au D.K.K., Hui Y. and Chow C.K., Implantable bone-anchored hearing aids to solve hearing problems, Hong Kong East & Hong Kong West Clusters Joint Rehabilitation Scientific Conference, 30 October 2004. |
| Au D.K.K., Moderator, International Conference on Recent Developments in Paediatric Audiology, Hong Kong, 4-5 December 2004. 2004. |
| Au D.K.K., Otological consideration prior to hearing aid fitting (Invited), Thai Speech-Language & Hearing Association Annual Convention, Thailand, 16 December 2004. |
| Au D.K.K., Outcome measurement in hearing aid fitting (Invited), Thai Speech-Language & Hearing Association Annual Convention, Thailand, 16 December 2004. |
| Au D.K.K., Representative of the University of Hong Kong in the Universita 21, Health Science Group, Annual Meeting at the University of Queensland, Brisbane, Australia, 28 September - 1 October. 2004. |
| Au D.K.K., Update trend in hearing aid evaluation (Invited), Thai Speech-Language & Hearing Association Annual Convention, Thailand, 16 December 2004. |
| Au D.K.K., Vice-Chairman (December 2004 - present), Hong Kong Society for the Deaf. 2005. |
| Au D.K.K., When to consider cochlear implants and bilateral cochlear implants? (Invited), The Philippine Society of Otolaryngology - Head and Neck Surgery, Inc. 48th PSO-HNS Annual Convention, The Philippines, 30 November - 3 December 2004. |
| Chow C.K., Hui Y. and Au D.K.K., A rare cause of sudden hearing loss in Chinese: cochlear involvement of sarcoidosis, The Internet Journal of Otohinolaryngology. 2004, 3 (1): On-line. |
| Chow C.K., Hui Y., Au D.K.K. and Chu K.M.Y., Minimally invasive surgery for different types of cochlear implant, Cochlear Implants International, The Proceedings of the Fourth Asian-Pacific Symposium on Cochlear Implant and Related Sciences, Taipei, Taiwan, 2003. 2004, 5 (Suppl 1): 75-77. |
| Chu K.M.Y., Au D.K.K., Hui Y., Chow C.K. and Wei W.I., Short electrode insertion in cochlear implantation: Speech perception performance of Cantonese-speaking subjects, Acta Oto-Laryngologica. 2005, 125: 718-724. |
| Chu K.M.Y., Au D.K.K., Hui Y., Chow C.K., Wong R.K. and Wei W.I., Short electrode insertion on cochlear implants: performance on speech perception, Cochlear Implant International, The Proceedings of the Fourth Asian-Pacific Symposium on Cochlear Implant and Related Sciences, Taipei, Taiwan, 2003. 2004, 5 (Suppl 1): 126-128. |
| Poon D.M.Y., Chow C.K., Au D.K.K., Hui Y. and Leung M.C.P., Translation of the dizziness handicap inventory into Chinese, validation of it, and evaluation of the quality of life of patients with chronic dizziness, The Annals of Otology, Rhinology & Laryngology. 2004, 113: 12. |
| Wong Y.K., Hui Y., Au D.K.K., Jin H. and Wei W.I., 人工耳蝸植入術的經濟學價值, Chinese Journal of Otorhinolaryngology. 2004, 39(12): 755-756. |
| Researcher : Cai C |
| List of Research Outputs |
| Fan S.T. and Cai C., 如何獲取最佳肝切除術結果 (Invited Lecture), 中國成都第七屆全國普通外科中青年醫師學術交流會暨第十屆全國普通外科學術會議, 2004年9月23日, 2004. |
| Researcher : Cai Q |
| List of Research Outputs |
| Tian L., Yuan Z., Cai Q., Lui Y., Thompson P., Tam P.K.H. and Lamb J.R., Combined treatment with cyclosporin A and rosiglitazone prevents chronic allograft rejection, 9th Basic Science Symposium of the Transplantation Society, LaBaule, France, 19-22 June 2005. |
| Researcher : Cai Z |
| List of Research Outputs |
| Cai Z., Chiu J. and He Q., Application of proteomics in the study of tumor metastasis, Genomics Proteomics & Bioinformatics. 2004, 2(3): 152-166. |
| Researcher : Chan HM |
| List of Research Outputs |
| Ren Y., Chen Y., Li W., Jiang G., Liu Q., Chan H.M. and Tam P.K.H., Anti-sense gene therapy for human neuroblastoma by targeting disruption of macrophage migration inhibitory factor (MIF): in vitro and nude mice studies, 51st Annual International Congress of British Association of Paediatric Surgeons, Oxford, U.K. 27-30 July 2004. |
| Researcher : Chan JKY |
| List of Research Outputs |
| Wong I.H.N., Chan J.K.Y. and Tam P.K.H., Epigenetic deregulation of cell cycle progression: a novel therapeutic strategy for pediatric cancer, 38th Annual Meeting of the Pacific Association of Pediatric Surgery, Vancouver, Canada, 22-26 May 2005. |
| Researcher : Chan KL |
| List of Research Outputs |
| Bai Y.Z., Chan K.L. and Tam P.K.H., Early surgical intervention of prenatally diagnosed congenital cystic adenomatoid malformation, 38th Annual Meeting of the Pacific Association of Pediatric Surgery, Vancouver, Canada, 22-26 May 2005. |
| Chan K.L., Tang M.H.Y. and Tam P.K.H., Non-cystic fibrosis meconium peritonitis: prenatal diagnosis, postnatal management and outcome, 38th Annual Meeting of the Pacific Association of Pediatric Surgery, Vancouver, Canada, 22-26 May 2005. |
| Chow P.C., Lee S.L., Tang M.H.Y., Chan K.L., Lee C.P., Tsoi N.S. and Lam B.C.C., Management and Outcome of Antenatally Diagnosed Congenital Cystic Adenomatoid Malformations, Ruby Jubilee Scientific Meeting, HK, 24-26 September 2004 (Abstract in Hong Kong Journal of Paediatrics (new series). Hong Kong, Medcom Limited, 2004, 9 (suppl): 19. |
| Leung W.C., Ngai C.S.W., Lam T.P.W., Chan K.L., Lao T.T.H. and Tang M.H.Y., Unexpected intrauterine death following resolution of hydrops fetalis after betamethasone treatment in a fetus with a large cystic adenomatoid malformation of the lung, Ultrasound Obstetrics and Gynecology. 2005, 25: 610-612. |
| Wang Q., Tam P.K.H. and Chan K.L., Congenital cystic adenomatoid malformation in children: 21 cases about studies and review of the literature, 19th Congress of the Asian Association of Paediatric Surgeons, Hong Kong, 28 November - 1 December 2004. |
| Researcher : Chan VSF |
| List of Research Outputs |
| Chan V.S.F., Chau S.Y., Tian L., Kwong S.K.Y., Quackenbush J., Dallman M., Lamb J.R. and Tam P.K.H., Sonic hedgehog promotes CD4+ T lymphocyte proliferation by modulating a subset of CD28-targeted genes, 9th Basic Science Symposium of the Transplantation Society, LaBaule, France, 19-22 June 2005. |
| Researcher : Chau SY |
| List of Research Outputs |
| Chan V.S.F., Chau S.Y., Tian L., Kwong S.K.Y., Quackenbush J., Dallman M., Lamb J.R. and Tam P.K.H., Sonic hedgehog promotes CD4+ T lymphocyte proliferation by modulating a subset of CD28-targeted genes, 9th Basic Science Symposium of the Transplantation Society, LaBaule, France, 19-22 June 2005. |
| Chau S.Y., A study of the expression of sonic hedgehog and its receptors in T cells and the identification of sonic hedgehog down-stream targets in activated CD4+ T cells, Thesis, Master of Philosophy, The University of Hong Kong. 2005. |
| Researcher : Chau SY |
| List of Research Outputs |
| Chan V.S.F., Chau S.Y., Tian L., Kwong S.K.Y., Quackenbush J., Dallman M., Lamb J.R. and Tam P.K.H., Sonic hedgehog promotes CD4+ T lymphocyte proliferation by modulating a subset of CD28-targeted genes, 9th Basic Science Symposium of the Transplantation Society, LaBaule, France, 19-22 June 2005. |
| Chau S.Y., A study of the expression of sonic hedgehog and its receptors in T cells and the identification of sonic hedgehog down-stream targets in activated CD4+ T cells, Thesis, Master of Philosophy, The University of Hong Kong. 2005. |
| Researcher : Chen L |
| List of Research Outputs |
| Yi C., Li Z., Yuan K., Qu X., Chen J., Wang G., Zhang H., Luo H., Zhu L., Jiang P., Chen L., Shen Y., Luo M., Zuo G., Hu J., Duan D., Nie Y., Shi X., Wang W., Han Y., Li T., Liu Y., Ding M., Deng H. and Xu X., Small molecules blocking the entry of SARS-Co V into host, Journal of Virology. 2004, 78(2)): 11334-11339. |
| Researcher : Chen T |
| List of Research Outputs |
| Chen T., Dendritic cell biology regulated by Epstein-Barr virus (EBV) and its associated tumors, Thesis, Master of Philosophy, The University of Hong Kong. 2005. |
| Researcher : Chen Y |
| List of Research Outputs |
| Chen Y., Lui V.C.H., Rooijen N.V. and Tam P.K.H., Depletion of intestinal resident macrophages prevents ischaemia reperfusion injury in gut, Gut. 2004, 53(12): 1772-1780. |
| Ren Y., Chen Y., Li W., Jiang G., Liu Q., Chan H.M. and Tam P.K.H., Anti-sense gene therapy for human neuroblastoma by targeting disruption of macrophage migration inhibitory factor (MIF): in vitro and nude mice studies, 51st Annual International Congress of British Association of Paediatric Surgeons, Oxford, U.K. 27-30 July 2004. |
| Researcher : Chen Y |
| List of Research Outputs |
| Chen Y., Lui V.C.H., Rooijen N.V. and Tam P.K.H., Depletion of intestinal resident macrophages prevents ischaemia reperfusion injury in gut, Gut. 2004, 53(12): 1772-1780. |
| Ren Y., Chen Y., Li W., Jiang G., Liu Q., Chan H.M. and Tam P.K.H., Anti-sense gene therapy for human neuroblastoma by targeting disruption of macrophage migration inhibitory factor (MIF): in vitro and nude mice studies, 51st Annual International Congress of British Association of Paediatric Surgeons, Oxford, U.K. 27-30 July 2004. |
| Researcher : Cheng CWN |
| List of Research Outputs |
| Tse E.Y.M., Loo T.Y., Cheung M.N.B., Chow L.W.C. and Cheng C.W.N., Arimidex inhibition on proliferation of human breast solid tumors measured by ATP bioluminescence, Life Sciences. 2004, 76: 827-834. |
| Researcher : Cheng SWK |
| Project Title: | The role of COX-2 and its metabolites in the pathogenesis of abdominal aortic aneurysm (AAA) |
| Investigator(s): | Cheng SWK, Cheuk LY |
| Department: | Surgery |
| Source(s) of Funding: | Small Project Funding |
| Start Date: | 11/2002 |
| Abstract: |
| To investigate the functional expression of the inducible COX-2 and its metabolites that may contribute to the apoptotic response involved in the pathogenesis of abdominal aortic aneurysm (AAA). |
| Project Title: | Molecular profiling of cellular receptors and their specific ligands in abdominal aortic aneurysms and in relation to pathogenesis |
| Investigator(s): | Cheng SWK, Cheuk LY |
| Department: | Surgery |
| Source(s) of Funding: | Small Project Funding |
| Start Date: | 11/2003 |
| Abstract: |
| To investigate the molecular change of a series of cellular receptors and their specific ligands in aneurysmal VSMCs, and study the mechanisms underlining the altered expression pattern. |
| Project Title: | Endovascular program for treating thoracic aortic dissections |
| Investigator(s): | Cheng SWK, Ting ACW |
| Department: | Surgery |
| Source(s) of Funding: | S.K. Yee Medical Foundation - General Award |
| Start Date: | 04/2004 |
| Abstract: |
| To initiate medical services for the poor and sick in the field of endovascular treatment of aortic dissections and provide equipment for such services. |
| Project Title: | Study of the pathological significance of COX-2 in vascular infection: implication of the therapeutic value of COX-2 inhibitor in abdominal aortic aneurysm (AAA) |
| Investigator(s): | Cheng SWK |
| Department: | Surgery |
| Source(s) of Funding: | Incentive Award for RGC CERG Fundable But Not Funded Projects |
| Start Date: | 07/2004 |
| Abstract: |
| Refer to hard copy |
| Project Title: | Study of the pathological significance of COX-2 in vascular infection: implication of the therapeutic value of COX-2 inhibitor in Abdominal Aortic Aneurysm (AAA) |
| Investigator(s): | Cheng SWK, Cheuk LY |
| Department: | Surgery |
| Source(s) of Funding: | Seed Funding Programme for Basic Research |
| Start Date: | 01/2005 |
| Abstract: |
| Refer hard copy |
| List of Research Outputs |
| Chan Y.K., Chiu P.K.Y., Cheng S.W.K. and Ho P., The incidence of deep vein thrombosis in elderly Chinese suffering hip fracture is low without prophylaxis: A prospective study using serial duplex ultrasound, Journal of Orthopaedic Surgery. 2004, 12(2): 178-183. |
| Cheng S.W.K., Abdominal aortic aneurysm morphology in Asians and its implications in endovascular stent grafting , The Annual Scientific Congress of Royal Australasian College of Surgeons, Perth, Australia, 9-13 May 2005. 2005. |
| Cheng S.W.K., Advances in vascular surgery (Editorial), Annals of the College of Surgeons of Hong Kong. 2004, 8(4): 127-128. |
| Cheng S.W.K., Ting A.C.W., Ho P. and Poon J.T.C., Aortic aneurysm morphology in Asians: features affecting endovascular stent graft application and design, Journal of Endovascular Therapy. 2004, 11: 605-612. |
| Cheng S.W.K., Ting A.C.W., Ho P. and Poon J.T.C., Aortic aneurysm morphology in Asians: features affecting endovascular stent graft application and design, The Nineteenth Annual Meeting of the Western Vascular Society, Victoria, Canada, 11-14 September 2004. |
| Cheng S.W.K., Aortic aneurysms and dissections: new treatment initiatives, The Federation's Annual Scientific Meeting 2004, The Federation of Medical Societies of Hong Kong, Hong Kong, 18 December 2004. 2004. |
| Cheng S.W.K., Chairman, First Symposium Session, The Third TWGHs Vascular Symposium, Kwong Wah Hospital, Hong Kong, 27 August 2004. 2005. |
| Cheng S.W.K., Chairman, International Session II: Foot Savage, The 33rd Congress of the Japanese Society for Vascualr Surgery, Asahikawa, Japan, 22-24 June 2005. 2005. |
| Cheng S.W.K., Chairman, Session on "Aortic Aneurysm, Operation or Stent Graft?", Hong Kong Surgical Forum, Hong Kong, 14-15 January 2005. 2005. |
| Cheng S.W.K., Chairman, Session on "Extracranial Carotid Disease", The 6th International Congress of Asian Vascular Society & 11th Conference of Vascular Society of India, Bangalore, India, 3-6 November 2004. 2005. |
| Cheng S.W.K., Chairman, Session on "Management of Aortic Dissection", Third Joint Guangzhou/Hong Kong Surgical Convention, First Affiliated Hospital, Sun Yat-Sen University, Guangzhou, China, 17 January 2005. 2005. |
| Cheng S.W.K., Chairman, Symposium on "Vasicose Veins", College of Surgeons of Hong Kong, Hong Kong, 25 April 2005. 2005. |
| Cheng S.W.K., EVAR for abdominal aortic aneurysm - Hong Kong experience, The Third TWGHs Vascular Symposium, Kwong Wah Hospital, Hong Kong, 27 August 2004. 2004. |
| Cheng S.W.K., EVR for abdominal aortic aneurysm - Hong Kong experience, Workshop on emergency AAA repair with endovascular stent graft, Department of Radiology and Imaging and Department of Surgery, Queen Elizabeth Hospital, Hong Kong, 5 September 2004. 2004. |
| Cheng S.W.K., Editor (2002 - present), Annals of the College of Surgeons of Hong Kong. 2005. |
| Cheng S.W.K., Editor-in-Chief (2003 - present), Asian Journal of Surgery. 2005. |
| Cheng S.W.K., Effect of irradiation on carotid artery, The Third TWGHs Vascular Symposium, Kwong Wah Hospital, Hong Kong, 27 August 2004. 2004. |
| Cheng S.W.K., Endovascular aneurysm repair: an Asian perspective, The 6th International Congress of Asian Vascular Society & 11th Conference of Vascular Society of India, Bangalore, India, 3-6 November 2004. 2004. |
| Cheng S.W.K., Endovascular aneurysm repair: unique challenges in an Asian population, Hong Kong Surgical Forum, Hong Kong, 14-15 January 2005. 2005. |
| Cheng S.W.K., Endovascular aneurysm repair: unique challenges in an Asian population, Third Joint Guangzhou/Hong Kong Surgical Convention, First Affiliated Hospital, Sun Yat-Sen University, Guangzhou, China, 17 January 2005. 2005. |
| Cheng S.W.K., Endovascular management of AAA, Vascular and Endovascular Workshop, Endovascular and Peripheral Vascular Interventions, Minimal Access Surgery Training Center, Pamela Youde Nethersole Eastern Hospital, Hong Kong, 8 November 2004. 2005. |
| Cheng S.W.K., Endovascular repair of abdominal aortic aneurysm: an Asian perspective, Shanghai International Vascular Conference and the 5th Shanghai-Tokyo Vascular Symposium, Shanghai, China, 19-20 November 2004. 2004. |
| Cheng S.W.K., Endovascular repair of abdominal aortic aneurysms, First Taiwan Transcatheter Therapeutics Live Demonstration Course and 93rd Meeting of the Taiwan Society of Cardiovascular Interventions, Taipei, Taiwan, 27-28 November 2004. 2004. |
| Cheng S.W.K., Endovascular stent graft: a new standard of treatment for aortic diseases (Invited Article), Medical Progress. 2005, 32(3): 115-120. |
| Cheng S.W.K., From TASC to Essential TASC, The 4th Korea-Japan Joint Meeting for Vascular Surgeons and the 41st Annual Spring Meeting of the Korean Society for Vascular Meeting, Jeju, Korea, 29-30 April 2005. 2005. |
| Cheng S.W.K., Irradiation induced carotid stenosis: natural history and treatment, The 6th International Congress of Asian Vascular Society & 11th Conference of Vascular Society of India, Bangalore, India, 3-6 November 2004. 2004. |
| Cheng S.W.K., Lecture International Session I: "Neurogenic thoracic outlet syndrome: diagnosis and management", The 33rd Congress of the Japanese Society for Vascular Surgery, Asahikawa, Japan, 22-24 June 2005. 2005. |
| Cheng S.W.K., Member (1996 - present), Editorial Board, Chinese Journal of Vascular Surgery. 2005. |
| Cheng S.W.K., Member (2002 - present), Editorial Board, Cutting Edge, College of Surgeons of Hong Kong Newsletter. 2005. |
| Cheng S.W.K., Member, Board of Governor, American College of Surgeons (Hong Kong Chapter), 90th Annual Clinical Congress of the American College of Surgeons, New Orleans, USA, 10-14 October 2004. 2005. |
| Cheng S.W.K., New treatment initiatives for aortic aneurysms and dissections: what we know and what we don't, Continuing Medical Education Programme, Education and Training Committee Surgical Division, Hong Kong Sanatorium & Hospital, Hong Kong, 6 May 2005. 2005. |
| Cheng S.W.K., Serena Yang Professor in Vascular Surgery (April 2005 - present), Endowed Professorship, The University of Hong Kong. 2005. |
| Cheng S.W.K., Symposium I Controveries in Surgery: "Endovascular treatment of aortic dissections", The 12th Annual Scientific Meeting of the College of Surgeons of Hong Kong, Hong Kong, 4-5 June 2005. 2005. |
| Cheng S.W.K., Vascular training in Hong Kong, The 6th International Congress of Asian Vascular Society & 11th Conference of Vascular Society of India, Bangalore, India, 3-6 November 2004. 2005. |
| Cheuk L.Y., Ting A.C.W. and Cheng S.W.K., Detection of C. pneumoniae by polymerase chain reaction-enzyme immunoassay in abdominal aortic aneurysm walls and its association with rupture, European Journal of Vascular and Endovascular Surgery. 2005, 29(2): 150-155. |
| Cheuk L.Y. and Cheng S.W.K., Expression of integrin alpha 5 betal and the relationship to collagen and elastin content in human suprarenal and infrarenal aortas, Vascular & Endovascular Surgery. 2005, 39(3): 245-251. |
| Ho P., Ting A.C.W. and Cheng S.W.K., Blood loss transfusion in elective abdominal aortic aneurysm surgery, Australian and New Zealand Journal of Surgery. 2004, 74(8): 631-634. |
| Ho P., Poon J.T.C., Ting A.C.W. and Cheng S.W.K., Routine immediate tracheostomy after ruptured abdominal aortic aneurysm repair improves hospital mortality, The 6th International Congress of Asian Vascular Society & 11th Conference of Vascular Society of India, Bangalore, India, 3-6 November 2004. |
| Mok V.W.K., Ting A.C.W., Law S.Y.K., Wong K.H., Cheng S.W.K. and Wong J., Combined endovascular stent grafting and endoscopic injection of fibrin sealant for aortoenteric fistula complicating esophagectomy, Journal of Vascular Surgery. 2004, 40(6): 1234-1237. |
| Ting A.C.W., Cheng S.W.K., Ho P. and Poon J.T.C., Endovascular repair for multiple Salmonella mycotic aneurysms of the thoracic aorta presenting with Cardiovocal syndrome, European Journal of Cardiothoracic Surgery. 2005, 26(1): 221-224. |
| Ting A.C.W., Cheng S.W.K., Ho P., Poon J.T.C., Wong Wu L.H. and Cheung G.C.Y., Surgical treatment for advanced chronic venous insufficiency in Hong Kong, Annals of the College of Surgeons of Hong Kong. 2004, 8(4): 135-140. |
| Ting A.C.W., Cheng S.W.K., Ho P., Poon J.T.C., Wong Wu L.H. and Cheung G.C.Y., Surgical treatment of advanced chronic venous insufficiency in Hong Kong, Second Chinese Venous Forum, Shanghai, China, 4-5 June 2005. 2005. |
| Ting A.C.W., Cheng S.W.K., Ho P., Poon J.T.C. and Tsu J.H.L., Surgical treatment of infected aneurysms and pseudoaneurysms of the thoacic and abdominal aorta, American Journal of Surgery. 2005, 189(2): 150-154. |
| Yiu W.K., Ting A.C.W. and Cheng S.W.K., Does endovascular repair of infrarenal AAA effect renal function?, The 6th International Congress of Asian Vascular Society & 11th Conference of Vascular Society of India, Bangalore, India, 3-6 November 2004. |
| Researcher : Cheuk LY |
| Project Title: | Detection of C. pneumoniae by polymerase chain reaction-enzyme immunoassay (PCR-EIA) in abdominal aortic aneurysm walls and its association with rupture |
| Investigator(s): | Cheuk LY, Cheng SWK, Ting ACW |
| Department: | Surgery |
| Source(s) of Funding: | Small Project Funding |
| Start Date: | 11/2004 |
| Abstract: |
| To elucidate the possible molecular association between the endovascular presence of C. pneumoniae DNA in aneurysmal lesions and its significance in ruptured Abdominal Aortic Aneurysms. |
| List of Research Outputs |
| Cheuk L.Y., Ting A.C.W. and Cheng S.W.K., Detection of C. pneumoniae by polymerase chain reaction-enzyme immunoassay in abdominal aortic aneurysm walls and its association with rupture, European Journal of Vascular and Endovascular Surgery. 2005, 29(2): 150-155. |
| Cheuk L.Y. and Cheng S.W.K., Expression of integrin alpha 5 betal and the relationship to collagen and elastin content in human suprarenal and infrarenal aortas, Vascular & Endovascular Surgery. 2005, 39(3): 245-251. |
| Researcher : Cheung CKY |
| List of Research Outputs |
| Luo Y., Lo C.M., Cheung C.K.Y., Lau G. and Fan S.T., Identification of hepatitis B virus specific lymphocytes in human liver allografts from hepatitis B virus immune donors (Abstract), The 6th Annual Scientific Meeting, Centre for the Study of Liver Disease, The University of Hong Kong, Hong Kong, 8 January 2005. |
| Luo Y., Lo C.M., Cheung C.K.Y., Lau G., Fan S.T. and Wong J., Potential role of resident intrahepatic lymphocytes in adoptive transfer of immunity to hepatitis B virus through liver transplantation (Poster Presentation), Digestive Disease Week, Chicago, U.S.A., 14-19 May 2004. |
| Yang Z., Poon R.T.P., Luo Y., Cheung C.K.Y., Ho D.W.Y., Lo C.M. and Fan S.T., Up-regulation of vascualr endothelial growth factor (VEGF) in small-for-size liver grafts enhances macrophage activities through VEGF receptor 2-dependent pathway, Journal of Immunology. 2004, 173(4): 2507-2515. |
| Researcher : Cheung ST |
| Project Title: | Characterization of the granulin/epithelin precursor gene in liver cancer |
| Investigator(s): | Cheung ST, Fan ST, Ng IOL |
| Department: | Surgery |
| Source(s) of Funding: | Merit Award for RGC CERG Funded Projects |
| Start Date: | 09/2003 |
| Abstract: |
| To characterize the role of the granulin/epithelin precursor (GEP) gene in the development and progression of liver cancer: 1) to examine the abnormalities of the GEP gene in normal, diseased and tumor specimens of the liver; 2) to understand the clinical and pathological significance of the GEP gene: to study the growth and proliferation function of the GEP gene in liver cancer; to identify the GEP regulated genes/pathways in liver cancer. |
| Project Title: | Characterization of the granulin/epithelin precursor gene in liver cancer |
| Investigator(s): | Cheung ST, Fan ST, Ng IOL |
| Department: | Surgery |
| Source(s) of Funding: | Competitive Earmarked Research Grants (CERG) |
| Start Date: | 09/2003 |
| Abstract: |
| To characterize the role of the granulin/epithelin precursor (GEP) gene in the development and progression of liver cancer: 1) to examine the abnormalities of the GEP gene in normal, diseased and tumor specimens of the liver; 2) to understand the clinical and pathological significance of the GEP gene: to study the growth and proliferation function of the GEP gene in liver cancer; to identify the GEP regulated genes/pathways in liver cancer. |
| Project Title: | Genes associated with liver cancer invasion |
| Investigator(s): | Cheung ST, Fan ST |
| Department: | Surgery |
| Source(s) of Funding: | Seed Funding Programme for Basic Research |
| Start Date: | 02/2004 |
| Completion Date: | 01/2005 |
| Abstract: |
| To study the proliferation and invasion potential of the membrane-type 1 matrix metalloproteinase (MT1-MMP/MMP14) gene in human liver cancer cell lines; to identify the MMP14 regulated genes/pathways. |
| Project Title: | Molecular and functional characterization of a novel prognostic marker, DNALI1, in hepatocellular carcinoma |
| Investigator(s): | Cheung ST |
| Department: | Surgery |
| Source(s) of Funding: | Incentive Award for RGC CERG Fundable But Not Funded Projects |
| Start Date: | 07/2004 |
| Abstract: |
| Refer to hard copy |
| Project Title: | Molecular target for liver cancer therapy |
| Investigator(s): | Cheung ST, Ho Jenny, Fan ST |
| Department: | Surgery |
| Source(s) of Funding: | Seed Funding Programme for Basic Research |
| Start Date: | 02/2005 |
| Abstract: |
| To study if GEP antibody has neutralizing function to inhibit cell proliferation, invasion and metastasis of liver cancer cells in vitro and in vivo. |
| List of Research Outputs |
| Chen X., Higgins J., Cheung S.T., Li R., Mason V., Montgomery K., Fan S.T., van de Rijin M. and So S., Novel endothelial cell markers in hepatocellular carcinoma, Modern Pathology. 2004, 17(10): 1198-1210. |
| Cheung S.T., Leung K.L., Ip Y.C., Chen X., Fong D.Y.T., Ng I.O.L., Fan S.T. and So S., Claudin-10 expression level is associated with recurrence of primary hepatocellular carcinoma, Clinical Cancer Research. 2005, 11(2 Pt 1): 551-556. |
| Cheung S.T., Clinical implication of gene expression profile by microarray - Workshop on molecular and cell biology for clinicians (Invited Lecture), The 9th Congress of the Asian Pacific Society of Respirology, Hong Kong, 10-13 December 2004. 2004. |
| Cheung S.T. and Poon R.T.P., Cyclins and CDKs in liver diseases, In: Dufour J.F., Clavien P.A., Signaling Pathways in Liver Diseases. Heidelberg, Springer-Verlag, 2005, 325-331. |
| Cheung S.T., Leung K.L., Kwok H.H., Wong S.Y. and Fan S.T., DNALI1 expression and gene polymorphism are associated with disease recurrence after curative surgery in hepatocellular carcinoma (Abstract), The 96th Annual Meeting of the American Association for Cancer Research, Anaheim, California, U.S.A., 16-20 April 2005. |
| Cheung S.T., Delineate molecular markers from the microarray profiling of hepatocellular carcinoma (Invited Lecture)., Hong Kong Surgical Forum, Hong Kong, July 9-10. 2004. |
| Cheung S.T. and Fan S.T., Gene expression profile of hepatocellular carcinoma (Abstract), Asian Journal of Surgery. 2005, 28(Suppl 2): S71. |
| Cheung S.T. and Fan S.T., Gene expression profile of hepatocellular carcinoma (Invited Lecture), The 4th International Meeting on Hepatocellular Carcinoma: Eastern and Western Experiences, Hong Kong, 14-16 December 2004. 2004. |
| Cheung S.T., Wong S.Y., Leung K.L., Chen X., So S., Ng I.O.L. and Fan S.T., Granulin-epithelin precursor (GEP) promotes growth and invasion of hepatocellular carcinoma (Abstract), The 6th Annual Scientific Meeting, Centre for the Study of Liver Disease, The University of Hong Kong, Hong Kong, 8 January 2005. |
| Cheung S.T., Wong S.Y., Leung K.L., Chen X., So S., Ng I.O.L. and Fan S.T., Granulin-epithelin precursor overexpression promotes growth and invasion in hepatocellular carcinoma, Clinical Cancer Research. 2004, 10(22): 7629-7636. |
| Cheung S.T., Identification of molecular markers for diagnosis and prognosis of liver cancer by microarray technology: principle and application (Invited Lecture)., COC Commissioned Training Programme 2004/05, Hospital Authority, Hong Kong, Nov 29 - Dec 1. 2004. |
| Cheung S.T., Ho J.C.Y., Leung K.L., Chen X., Fong D.Y.T., So S. and Fan S.T., Transcript AA454543 is a novel prognostic marker for hepatocellular carcinoma after curative partial hepatectomy, Neoplasia. 2005, 7(2): 91-98. |
| Ho J.C.Y., Cheung S.T., Leung K.L., Ng I.O.L. and Fan S.T., Decreased expression of cytochrome P450 2E1 is associated with poor prognosis of hepatocellular carcinoma, International Journal of Cancer. 2004, 111(4): 494-500. |
| Ho J.C.Y., Cheung S.T. and Fan S.T., Up-regulation of glycosylphatidylinositols anchor attachment protein (GAA1), a novel oncogene, in hepatocellular carcinoma (Abstract), Asian Journal of Surgery. 2005, 28(Suppl 2): S89. |
| Ho J.C.Y., Cheung S.T. and Fan S.T., Up-regulation of glycosylphatidylinositols anchor attachment protein (GAA1), a novel oncogene, in hepatocellular carcinoma (Abstract), The 4th International Meeting on Hepatocellular Carcinoma: Eastern and Western Experiences, Hong Kong, 14-16 December 2004. |
| Ho J.C.Y., Cheung S.T. and Fan S.T., Up-regulation of glycosylphatidylinositols anchor attachment protein 1 (GAA1), a novel oncogene, in hepatocellular carcinoma (Abstract), The 6th Annual Scientific Meeting, Centre for the Study of Liver Disease, The University of Hong Kong, Hong Kong, 8 January 2005. |
| Patil M.A., Chua M.S., Pan K.H., Lin R., Lih C.J., Cheung S.T., Ho C., Li R., Fan S.T., Cohen S.N., Chen X. and So S., An integrated data analysis approach to characterize genes highly expressed in hepatocellular carcinoma, Oncogene. 2005, 24(23): 3737-3747. |
| Patil M.A., Zhang J., Ho C., Cheung S.T., Fan S.T. and Chen X., Hedgehog signaling in human hepatocellular carcinoma (Abstract), Proceedings of the American Association for Cancer Research. 2005, 46: 3942. |
| Patil M.A., Zhang J., Ho C., Cheung S.T., Fan S.T. and Chen X., Hedgehog signaling in human hepatocellular carcinoma (Abstract), The 96th Annual Meeting of the American Association for Cancer Research, Anaheim, U.S.A., 16-20 April 2005. |
| Researcher : Cheung WH |
| List of Research Outputs |
| Cheung W.H., Yip W.P., Yu W.Y. and Che C.M., Oxidation of Ansioles to p-Benzoquinones Monoketals catalyzed by a Ruthenium complex of 1,4,7-Trimethyl-1, 4, 7-TriazacyclononaNe with tert-Buty1 Hydroperoxide, Canadian Jouranl of Chemistry. 2005, 83(6-7): 521-536. |
| Researcher : Chiu SW |
| List of Research Outputs |
| Gao Z., Sun H., Chiu S.W., Lau C.P. and Li G.R., Effects Of Diltiazem And Nifedipine On Transient Outward And Ultra-rapid Delayed Rectifier Potassium Currents In Human Atrial Myocytes, Br J Pharmacol. 2005, 144: 495-604. |
| Ku C.F., Lo C.Y., Chan W.F., Chiu S.W., Fan S.T. and Lam K.S.L., Resection of phaeochromocytoma extending into the right atrium in a patient with multiple endocrine neoplasia type 2A, Hong Kong Medical Journal. 2005, 11(1): 59-62. |
| Tian M., Dong M., Chiu S.W., Lau C.P. and Li G.R., Effects Of Clotrimazole On Human Cardiac Repolarization Potassium Currents, Journal of Hong Kong College Cardiology. 2004, 12(3/4): 101(P11). |
| Researcher : Choi KM |
| List of Research Outputs |
| Choi K.M., Cho C.H. and Chu K.M., Tumour infiltrating lymphocytes (TILs) - A prognostic factor for gastric adenocarcinoma, 9th Research Postgraduate Symposium, Faculty of Medicine, The University of Hong Kong, Hong Kong, 4 December 2004. |
| Researcher : Chow CK |
| List of Research Outputs |
| Au D.K.K., Hui Y., Chow C.K. and Wei W.I., 香港失聰幼兒早期人工耳蝸植入後的聽力和言語康復, Chinese Scientific Journal of Hearing and Speech Rehabilitation. 2004, 6: 14-16. |
| Au D.K.K., Chu K.M.Y., Chow C.K., Hui Y. and Wei W.I., Cognitive abilities of patients with cochlear implant in the discrimination of tone stimuli with minimal contrast, Cochlear Implant International, The Proceedings of the Fourth Asian-Pacific Symposium on Cochlear Implant and Related Sciences, Taipei, Taiwan, 2003. 2004, 5 (Suppl. 1): 179-181. |
| Au D.K.K., Hui Y. and Chow C.K., Implantable bone-anchored hearing aids to solve hearing problems, Hong Kong East & Hong Kong West Clusters Joint Rehabilitation Scientific Conference, 30 October 2004. |
| Chow C.K., Hui Y. and Au D.K.K., A rare cause of sudden hearing loss in Chinese: cochlear involvement of sarcoidosis, The Internet Journal of Otohinolaryngology. 2004, 3 (1): On-line. |
| Chow C.K., Hui Y., Au D.K.K. and Chu K.M.Y., Minimally invasive surgery for different types of cochlear implant, Cochlear Implants International, The Proceedings of the Fourth Asian-Pacific Symposium on Cochlear Implant and Related Sciences, Taipei, Taiwan, 2003. 2004, 5 (Suppl 1): 75-77. |
| Chu K.M.Y., Au D.K.K., Hui Y., Chow C.K. and Wei W.I., Short electrode insertion in cochlear implantation: Speech perception performance of Cantonese-speaking subjects, Acta Oto-Laryngologica. 2005, 125: 718-724. |
| Chu K.M.Y., Au D.K.K., Hui Y., Chow C.K., Wong R.K. and Wei W.I., Short electrode insertion on cochlear implants: performance on speech perception, Cochlear Implant International, The Proceedings of the Fourth Asian-Pacific Symposium on Cochlear Implant and Related Sciences, Taipei, Taiwan, 2003. 2004, 5 (Suppl 1): 126-128. |
| Poon D.M.Y., Chow C.K., Au D.K.K., Hui Y. and Leung M.C.P., Translation of the dizziness handicap inventory into Chinese, validation of it, and evaluation of the quality of life of patients with chronic dizziness, The Annals of Otology, Rhinology & Laryngology. 2004, 113: 12. |
| Researcher : Chow LWC |
| Project Title: | Chemosensitivity study using a breast cancer cell line |
| Investigator(s): | Chow LWC |
| Department: | Surgery |
| Source(s) of Funding: | Other Funding Scheme |
| Start Date: | 05/1996 |
| Abstract: |
| To test the effect of combination chemotherapy on cell growth in a breast cancer cell line. |
| Project Title: | Radioguided surgery and breast cancer management courses and seminars |
| Investigator(s): | Chow LWC, Kwong A. |
| Department: | Surgery |
| Source(s) of Funding: | Professional Services Development Assistance Scheme |
| Start Date: | 03/2003 |
| Abstract: |
| To host a series of workshops and seminars, once every three months for a period of two years, on the radio guided sentinel node biopsy procedure. Other breast cancer management information and techniques will also be presented. |
| Project Title: | The determination of predictive markers related to micro-metastasis in breast cancer patients |
| Investigator(s): | Chow LWC |
| Department: | Surgery |
| Source(s) of Funding: | Incentive Award for RGC CERG Fundable But Not Funded Projects |
| Start Date: | 07/2004 |
| Abstract: |
| Refer to hard copy |
| Project Title: | Chemosensitivity testing service for selection of chemotherapy in breast cancer patients |
| Investigator(s): | Chow LWC, Loo TY |
| Department: | Surgery |
| Source(s) of Funding: | S.K. Yee Medical Foundation - General Award |
| Start Date: | 10/2004 |
| Abstract: |
| To establish the proposed chemosensitivity assay as a service and be done for patients requiring chemotherapy. |
| Project Title: | Profiling DNA alterations in breast cancer by comparative genomic hybridization |
| Investigator(s): | Chow LWC |
| Department: | Surgery |
| Source(s) of Funding: | Seed Funding Programme for Basic Research |
| Start Date: | 01/2005 |
| Abstract: |
| Refer to hard copy |
| List of Research Outputs |
| Chow L.W.C., Chairman, Organizing Committee, 1st Annual Conference, Organization of Oncology and Translational Research, Hong Kong, October. 2004. |
| Chow L.W.C., Clinical experience on COX-2 inhibition in breast cancer (Invited), 1st Annual Conference, Organization for Oncology and Translational Research, Hong Kong, 15-16 October 2004. |
| Chow L.W.C., Co-chairman, Oncology Conference, Guang-chou, October. 2004. |
| Chow L.W.C., Current direction of COX-2 inhibition in breast cancer (Keynote Lecture), Second Asia Pacific Oncology Summit: Commitment to Advancing the Treatment of Solid Tumors, Suzhou, China, 8-10 October 2004. 2004. |
| Chow L.W.C., Current direction on COX-2 inhibition in breast cancer (Keynote Lecture), Second Asia Pacific Oncology Summit: Commitment to advancing the treatment of solid tumors, Suzhou, China, October. 2004. |
| Chow L.W.C., Neoadjuvant therapy for brest cancer, Tohoku University, Sendai, Japan, 1-2 July 2004 . 2004. |
| Chow L.W.C., New paradigm in the treatment of breast cancer, 2004 National Congress on the Diagnosis and Management of Breast Cancer, The Breast Society of the Chinese Medical Association, Chongqing, China, September. 2004. |
| Chow L.W.C., Paradigm shift in the management of breast cancer, Special Lecture, Shanghai Cancer Hospital, Shanghai, China, 9-10 October 2004. 2004. |
| Chow L.W.C., Sentinel lymph node biopsy - here to stay, Asian Journal of Surgery. 2004, 27: 255. |
| Lam W.W.T., Fielding R., Chan M., Chow L.W.C. and Or A., Gambling with your life: The process of breast cancer treatment decision making in Chinese women, Psycho-Oncology. Chichester, England, John Wiley & Sons, 2005, 14: 1-15. |
| Lam W.W.T., Fielding R., Chow L.W.C., Chan M., Leung G.M. and Ho E.Y.Y., The Chinese medical interview satisfaction scale-revised (C-MISS-R): Development and validation, Quality of Life Research. Dordrecht, Netherlands, Kluwer Academic, 2005, 14: 1187-1192. |
| Law M., Cheng K.C., Wu P.W., Ho W.Y. and Chow L.W.C., Effective dose in sentinel lymph node imaging, British Journal of Radiology. 2004, 77: 709. |
| Loo T.Y., Cheung M.N.B. and Chow L.W.C., Production of matrix metalloproteinases in specific subpopulations of human-patient breast cancer invading in three dimensional culture system, Life Sciences. 2004, 76: 743-752. |
| Toi M., Bando H. and Chow L.W.C., Novel insights in clinicals trials with preoperative systemic therapy for primary breast cancer, Biomedicine & Pharmacotherapy. 2004, 58: 531-535. |
| Toi M., Atiqur Rahman M., Bando H. and Chow L.W.C., Thymidine phosphorylase (platelet-derived endothelial-cell growth factor) in cancer biology and treatment, Lancet Oncology. 2005, 6: 158-166. |
| Toi M., Takebayashi Y. and Chow L.W.C., Translational research in breast cancer, Breast Cancer. 2005, 12(2): 86-90. |
| Tse E.Y.M., Loo T.Y., Cheung M.N.B., Chow L.W.C. and Cheng C.W.N., Arimidex inhibition on proliferation of human breast solid tumors measured by ATP bioluminescence, Life Sciences. 2004, 76: 827-834. |
| Zhu L., Chow L.W.C., Loo T.Y., Guan X.Y. and Toi M., Her2/neu expression predicts the response to antiaromatase neoadjuvant therapy in primary breast cancer: subgroup analysis from celecoxib antiaromatase neoadjuvant trial, Clinic Cancer Research. 2004, 10(14): 4639-4644. |
| Zhu L., Lam C.K. and Chow L.W.C., Sentinel lymph node biopsy or detection of micrometastasis in bone marrow: which might be an alternative to axillary lymph node dissection in breast cancer patients?, Asian Journal of Surgery. 2004, 27: 279-283. |
| Researcher : Chu ACH |
| List of Research Outputs |
| Chu A.C.H., Invited Chairman for the Session on "Adjuvant chemotherapy", The 6th International Gastric Cancer Congress, 4-7 May 2005, Yokohama, Japan. 2005. |
| Researcher : Chu KM |
| Project Title: | Inhibition of growth factors expression in gastric adenocarcinoma by small interfering RNAs |
| Investigator(s): | Chu KM, Leung SY, Yuen ST, Ko S |
| Department: | Surgery |
| Source(s) of Funding: | Incentive Award for RGC CERG Fundable But Not Funded Projects |
| Start Date: | 07/2003 |
| Abstract: |
| To investigate: (1) does RNAi model exist in gastric cancer cell lines?; (2) can gene specific siRNA duplexes elicit gene suppression?; (3) can in vitro results be applied to in vivo model? |
| Project Title: | The role of Id proteins in gastric cancer |
| Investigator(s): | Chu KM, Ko S |
| Department: | Surgery |
| Source(s) of Funding: | Seed Funding Programme for Basic Research |
| Start Date: | 02/2004 |
| Completion Date: | 01/2005 |
| Abstract: |
| To investigate the expression levels of mRNA and proteins of Id proteins such as Id1, Id2 and Id3 in gastric cancer. |
| Project Title: | Characterization of the effect of MAPK inhibitor PD98059 on RON-activated anti-apoptotic pathway in gastric cancer |
| Investigator(s): | Chu KM, Ko S |
| Department: | Surgery |
| Source(s) of Funding: | Seed Funding Programme for Basic Research |
| Start Date: | 02/2005 |
| Abstract: |
| Refer hard copy |
| List of Research Outputs |
| Au W.Y., Kwok J.S.Y., Chu K.M. and Ma E.S.K., Life-threatening cryoglobulinemia in HCV negative Southern Chinese and a novel association with structural aortic abnormalities, Annals of Hematology. 2005, 84: 95-98. |
| Chan O.O., Chu K.M., Sun Y., Cheung K.L., Lam S.K., Yuen R.M.F., Hui W.M. and Wong B.C.Y., The association between Interleukin 1 beta polymorphism and hypermethylation at tumor suppressor genes in gastric cancer. Conference paper at the Annual Meeting of the American Gastroenterology Associatoin, Digestive Diseases Week (DDW) Chicago, Illinois, USA. May 14-19, Gastroenterology. 2005, 128(4 Suppl 2): A399. |
| Choi K.M., Cho C.H. and Chu K.M., Tumour infiltrating lymphocytes (TILs) - A prognostic factor for gastric adenocarcinoma, 9th Research Postgraduate Symposium, Faculty of Medicine, The University of Hong Kong, Hong Kong, 4 December 2004. |
| Chok S.H., Fan J., Kwok K.F. and Chu K.M., A prospective study of patients with giant gastric ulcer, 19th World Congress of the International Society of Digestive Surgery (ISDS), Yokohama, Japan, 8-11 December 2004. Journal of Gastrointestinal Surgery . 2004, 8(7S): 193A. |
| Chok S.H., Fan J., Kwok K.F. and Chu K.M., A prospective study of patients with giant gastric ulcer, Journal of Gastrointestinal Surgery 2004. 2004, 8(7S): 193A. |
| Chu K.M., "Common gastrointestinal disorders in Hong Kong", Lecture for Master of Science in Nursing, (Subject SN581 "Primary Care Problems of Adults I"), The Hong Kong Polytechnic University, 18 October 2004, Hong Kong. 2004. |
| Chu K.M., "Gastric cancer - what you need to know in 2004", The Alimentary Disease Weekend, Faculty of Medicine, The University of Hong Kong, 18-19 September 2004, Hong Kong. 2004. |
| Chu K.M., "Gastric cancer", Preparatory Course for Exit Examination in General Surgery, The College of Surgeons of Hong Kong and Department of Surgery, The University of Hong Kong, 2 September 2005. 2005. |
| Chu K.M., "Gastric tumours", Postgraduate Course, 12th Annual Scientific Meeting, The College of Surgeons of Hong Kong, 4 June 2005, Hong Kong. 2005. |
| Chu K.M., "Gastrointestinal diseases", Core Module 14 "Biological Basis of Common Health Problems", Master of Medical Science, The University of Hong Kong, 24 March 2005, Hong Kong. 2005. |
| Chu K.M., "Gastrointestinal stromal tumour", The 10th Shanghai / Hong Kong Surgical Convention, 11 July 2005, Shanghai, China. 2005. |
| Chu K.M., "Upper GI Surgery", Post-registration Certificate Course in Peri-operative Nursing, Institute of Advanced Nursing Studies, Hospital Authority, 19 March 2005, Hong Kong. 2005. |
| Chu K.M., "Upper Gastrointestinal Surgery: Common UGI disorders and surgeries", Lecture for Diploma in Surgical Nursing (Course Code HS 34-120-00(31)), School of Professional and Continuing Education (SPACE), The University of Hong Kong, 2 April 2004, Hong Kong. 2004. |
| Chu K.M., :Laparoscopic gastrectomy for cancer - the controversies", The Hands-on Cadaver Advanced Laparoscopic Gastrointestinal Surgery Course, The University of Hong Kong, 17-18 June 2005, Hong Kong. 2005. |
| Chu K.M., Chairman for the Session on "Esophageal Surgery", Hong Kong Surgical Forum, 9-10 July 2004, Hong Kong. 2004. |
| Chu K.M., Chairman for the Session on "Gastrointestinal Cancer", The Hong Kong Surgical Forum, 8-9 July 2005, Hong Kong. 2005. |
| Chu K.M., Chairperson for Plenary Session on "Surgical Excellence 1", The Joint Meeting of the 30th Annual Scientific Meeting of the Royal College of Surgeons of Thailand and the 15th Asian Congress of Surgery, 20-23 July 2005, Pattaya, Thailand. 2005. |
| Chu K.M., Gastric rupture could result from any form of barotrauma to the stomach, British Medical Journal. 2004, on-line. |
| Chu K.M., Guest Editorship, Symposium on upper gastrointestinal surgery, Surgical Practice (The College of Surgeons of Hong Kong). 2005. |
| Chu K.M., Invited referee (1997 - present), Asian Journal of Surgery. 2005. |
| Chu K.M., Invited referee (1998, 1999, 2004), Journal of Gastroenterology and Hepathology. 2005. |
| Chu K.M., Invited referee (1999 - present), Annals of the College of Surgeons of Hong Kong. 2005. |
| Chu K.M., Invited referee (1999 - present), Digestive Surgery. 2005. |
| Chu K.M., Invited referee (2002, 2004), Hong Kong Medical Journal. 2005. |
| Chu K.M., Invited referee (2002, 2004), Surgery. 2005. |
| Chu K.M., Invited referee (2003 - present), British Journal of Cancer. 2005. |
| Chu K.M., Invited referee (2004 - present), Digestive and Liver Disease. 2005. |
| Chu K.M., Invited referee (Expert Reviewer for ICRETT (2000, 2002, 2004, 2005), International Union Against Cancer (UICC) Fellowships application. 2005. |
| Chu K.M., Invited speaker on "Management of gastric cancer in Hong Kong" and panellist in the Symposium "The best treatment for the gastric cancer between Japan and Asia", The 59th Annual Meeting of the Japanese Society of Gastroenterological Surgery, 21-23 July 2004, Kagoshima, Japan. 2004. |
| Chu K.M., Management of gastric cancer - have we made any progress? (Invited Lecture), The 6th Joint Annual Scientific Meeting on GI Diseases, The Hong Kong Society of Gastroenterology, The Hong Kong Society of Digestive Endoscopy, The Hong Kong Society of Coloproctology, The Hong Kong Association for the Study of Liver Diseases, and The Hong Kong Society of Gastrointestinal Motility, 9 October 2004, Hong Kong. 2004. |
| Chu K.M., Management of gastric cancer - have we made any progress? (Invited Plenary Lecture) , The 64th Scientific Meeting of the Taiwan Surgical Association, 26-27 March 2005, Taipei, Taiwan. 2005. |
| Chu K.M., Member of Editorial Board (2000 - present), Annals of Cancer Research and Therapy. 2005. |
| Chu K.M., Membership of Editorial Board (2003 - present), Cancer Therapy. 2005. |
| Chu K.M., Membership of Editorial Board (Associate Editor), Asian Journal of Surgery. 2005. |
| Chu K.M., Membership of Editorial Board, Cutting Edge (The College of Surgeons of Hong Kong). 2005. |
| Chu K.M., Kwok K.F., Law S.Y.K. and Wong K.H., Patients with Helicobacter pylori positive and negative duodenal ulcers have distinct clinical characteristics, World Journal of Gastroenterology . 2005, 11(23): 3518-3522. |
| Chu K.M., Video presentation of "Distal radical gastrectomy with D2 lymph node dissection", The Symposium for Inauguration of Asian Clinical Trials for Gastric Cancer, National Cancer Centre Hospital, 12-13 November 2004, Tokyo, Japan. 2004. |
| Fan J., Chok S.H., kwok K.F. and Chu K.M., Platelet count is a prognostic factor for gastric adenocarcinoma, 19th World Congress of the International Society of Digestive Surgery (ISDS), Yokohama, Japan, 8-11 December 2004. Journal of Gastrointestinal Surgery . 2004, 8(7S): 198A-199A. |
| Fan J., Chok S.H., Kwok K.F. and Chu K.M., Platelet count is a prognostic factor for gastric adenocarcinoma, Journal of Gastrointestinal Surgery 2004. 2004, 8(7S): 198A-199A. |
| He Q., Cheung Y.H., Leung S.Y., Yuen S.T., Chu K.M. and Chiu J., Diverse proteomic alterations in gastric adenocarcinoma, Proteomics. 2004, 4(10): 3276-3287. |
| Ko S., Luk J.M.C., Wong W.Y., Leung S.Y. and Chu K.M., CDX2 co-localizes with liver-intestine cadherin in intestinal metaplasia and adenocarcinoma of stomach, 6th International Gastric Cancer of Congress, Yokohama, Japan, 4-7 May 2005. |
| Ko S., Chu K.M., Luk J.M.C., Wong W.Y., Yuen S.T., Leung S.Y. and Wong J., CDX2 co-localizes with liver-intestine cadherin in intestinal metaplasia and adenocarcinoma of stomach, Journal of Pathology . 2005, 205: 615-622. |
| Law S.Y.K., Wong K.H., Kwok K.F., Chu K.M. and Wong J., Predictive factors for postoperative pulmonary complications and mortality after esophagectomy for cancer, Annals of Surgery. 2004, 240(5): 791-800. |
| Leung S.Y., Yuen S.T., Chu K.M., Mathy J.A., Li R., Chan A.S.Y., Law S.Y.K., Wong J., Chen X. and So S., Expression profiling identifies chemokine (C-C motif) ligand 18 as an independent prognostic indicator in gastric cancer, Gastroenterology. 2004, 127(2): 457-469. |
| Li V.S.W., Wong C.W., Chan T.L., Chan A.S.W., Zhao W., Chu K.M., Chen X., Yuen S.T., Leung S.Y. and So S., Mutations of PIK3CA in gastric adenocarcinoma, BioMed Central Cancer. 2005, 5: 29. |
| Ren Z., Borody T., Pang G., Dunkley M., Clancy R., Xia H.H.X., Chu K.M., Wong J. and Wong B.C.Y., Evaluation of anti-Helicobacter pylori IgG2 antibody for the diagnosis of Helicobacter pylori infection in Western and Chinese populations, Alimentary Pharmacology & Therapeutics. 2005, 21: 83-89. |
| Shin V.Y., Liu S.L.E., Ye Y., Koo M.W.L., Chu K.M. and Cho C.H., A mechanistic study of cigarette smoke and cyclooxygenase-2 on the proliferation of gastric cancer cells, Advances in GI Pharmacology, 20-22 November 2004, Shiga, Japan. 2004, 59. |
| Subramanian S., West R.B., Corless C.L., Ou W., Rubin B.P., Chu K.M., Leung S.Y., Yuen S.T., Zhu S., Hernandez-Boussard T., Montgomery K., Nielsen T.O., Patel R.M., Goldblum J.R., Heinrich M.C., Fletcher J.A. and van de Rijn M.V.D., Gastrointestinal stromal tumors (GISTs) with KIT and PDGFRA mutations have distinct gene expression profiles, Oncogene. 2004, 2004: 7780-7790. |
| Researcher : Chu KMY |
| List of Research Outputs |
| Au D.K.K., Chu K.M.Y., Chow C.K., Hui Y. and Wei W.I., Cognitive abilities of patients with cochlear implant in the discrimination of tone stimuli with minimal contrast, Cochlear Implant International, The Proceedings of the Fourth Asian-Pacific Symposium on Cochlear Implant and Related Sciences, Taipei, Taiwan, 2003. 2004, 5 (Suppl. 1): 179-181. |
| Chow C.K., Hui Y., Au D.K.K. and Chu K.M.Y., Minimally invasive surgery for different types of cochlear implant, Cochlear Implants International, The Proceedings of the Fourth Asian-Pacific Symposium on Cochlear Implant and Related Sciences, Taipei, Taiwan, 2003. 2004, 5 (Suppl 1): 75-77. |
| Chu K.M.Y., Au D.K.K., Hui Y., Chow C.K. and Wei W.I., Short electrode insertion in cochlear implantation: Speech perception performance of Cantonese-speaking subjects, Acta Oto-Laryngologica. 2005, 125: 718-724. |
| Chu K.M.Y., Au D.K.K., Hui Y., Chow C.K., Wong R.K. and Wei W.I., Short electrode insertion on cochlear implants: performance on speech perception, Cochlear Implant International, The Proceedings of the Fourth Asian-Pacific Symposium on Cochlear Implant and Related Sciences, Taipei, Taiwan, 2003. 2004, 5 (Suppl 1): 126-128. |
| Researcher : Chu KW |
| List of Research Outputs |
| Choi H.K., Law W.L., Ho J.W.C. and Chu K.W., Value of gastrografin in adhesive small bowel obstruction after unsuccessful conservative treatment: a prospective evaluation, World Journal of Gastroenterology. 2005, 11 (24): 3742-3745. |
| Law W.L. and Chu K.W., Abdominoperineal resection is associated with poor oncological outcome, British Journal of Surgery. 2004, 91(11): 1493-1499. |
| Law W.L. and Chu K.W., Anterior resection for rectal cancer with mesorectal excision: a prospective evaluation of 622 patients, Annals of Surgery. 2004, 240(2): 260-268. |
| Law W.L., Ho J.W.C., Chan T.T., Au G.K.H. and Chu K.W., Outcome of anterior resection for stage II rectal cancer without radiation: the role of adjuvant chemotherapy, Diseases of the Colon & Rectum. 2005, 48(2): 218-226. |
| Researcher : Chu SSM |
| List of Research Outputs |
| Cheung M.C., Lee F.C.W., Chu S.S.M., Leung S.Y.L., Wong B.B.W., Ho K.L. and Tam P.C., Laparoscopic nephrectomy: an early experience at Queen Mary Hospital, Hong Kong Medical Journal. 2005, 11(1): 7-11. |
| Tsu H.L., Cheung M.C., Chu S.S.M., Lee F.C.W. and Tam P.C., Laparoscopic live donor nephrectomy: is there any difference in outcome compared with its conventional open counterpart?, International Journal of Urology. 2004, 11(Suppl): A4. |
| Researcher : Chung PY |
| List of Research Outputs |
| Chung P.Y., The role of DC-SIGN in the regulation of the function and survival of dendritic cells in HIV-1 infection, Thesis, Doctor of Philosophy, The University of Hong Kong. 2005. |
| Researcher : Fan ST |
| Project Title: | S.K. Yee Medical Foundation Fellowship in hepatobiliary surgery |
| Investigator(s): | Fan ST |
| Department: | Surgery |
| Source(s) of Funding: | S.K. Yee Medical Foundation - General Award |
| Start Date: | 11/2000 |
| Abstract: |
| To train surgeons from less developed cities in China to acquire the technique and knowledge in dealing with complex hepatobiliary problems so as to benefit patients who cannot afford the cost of receiving treatment in cities like Beijing, Shanghai and Guangzhou. |
| Project Title: | Novel strategy to prevent small-for-size graft failure during liver transplantation |
| Investigator(s): | Fan ST, Man K |
| Department: | Surgery |
| Source(s) of Funding: | Competitive Earmarked Research Grants (CERG) |
| Start Date: | 11/2002 |
| Completion Date: | 05/2005 |
| Abstract: |
| The project aims at identifying the effect of a new nitric oxide donor FK 409 on hepatic sinusoids and to optimize the dosage and injection timing or route. The study will monitor the portal hemodynamics and intragraft genes expression at the early phase after reperfusion in a rat liver transplantation using different graft sizes. |
| Project Title: | Rescue of marginal liver graft from ischemia-reperfusion injury by FTY720 combined with gene therapy using Egr-1 dominant negative mutant and A20 |
| Investigator(s): | Fan ST, Man K, Xu R |
| Department: | Surgery |
| Source(s) of Funding: | Incentive Award for RGC CERG Fundable But Not Funded Projects |
| Start Date: | 07/2003 |
| Abstract: |
| To investigate the effectiveness of combined drug (FTY 720) and gene therapies (using a novel viral vectors) in improving the long-term function of marginal grafts in liver transplantation. |
| Project Title: | Clinical and genetic study of novel genes associated with early recurrence in hepatocellular carcinoma |
| Investigator(s): | Fan ST, Cheung ST |
| Department: | Surgery |
| Source(s) of Funding: | Small Project Funding |
| Start Date: | 11/2003 |
| Completion Date: | 10/2004 |
| Abstract: |
| To study the expression and structural abnormalities of the novel prognostic markers in human liver samples. |
| Project Title: | Differential proteomic analysis of biomarkers for primary and recurrent hepatocellular carcinoma |
| Investigator(s): | Fan ST, Luk JMC, Leng X.S., Peng J.R. |
| Department: | Surgery |
| Source(s) of Funding: | NSFC/RGC Joint Research Scheme |
| Start Date: | 12/2003 |
| Abstract: |
| To identify potential biomarkers for HCC in liver tissues by proteomic analysis; to detect HCC-specific protein biomarkers in serum by ProteinChip; to predict proteomic analysis of HCC patients with high-risk recurrence after surgery. |
| Project Title: | Clinical significance of claudin-10 expression in hepatocellular carcinoma |
| Investigator(s): | Fan ST |
| Department: | Surgery |
| Source(s) of Funding: | Incentive Award for RGC CERG Fundable But Not Funded Projects |
| Start Date: | 07/2004 |
| Abstract: |
| Refer to hard copy |
| Project Title: | The potential role of cytoplasmic p27kip1 on metastatic tumor pathogenesis of hepatocellular carcinoma |
| Investigator(s): | Fan ST, Wang X, Poon RTP |
| Department: | Surgery |
| Source(s) of Funding: | Seed Funding Programme for Basic Research |
| Start Date: | 01/2005 |
| Abstract: |
| Refer to hard copy |
| Project Title: | The significance of focal adhesion kinase and cell adhesion kinas &beta and their C-terminal non-kinases in liver cancer invsasion and migration |
| Investigator(s): | Fan ST, Man K |
| Department: | Surgery |
| Source(s) of Funding: | Seed Funding Programme for Basic Research |
| Start Date: | 03/2005 |
| Abstract: |
| Refer to hard copy |
| List of Research Outputs |
| Au W.Y., Liu C.L., Lo C.M., Fan S.T. and Ma E.S.K., Potential role for platelet apheresis for post-liver transplant thrombocytosis complicating portal vein thrombosis, Journal of Clinical Apheresis. 2004, 19(4): 192-196. |
| Chan S.C., Liu C.L., Lo C.M. and Fan S.T., Applicability of histidine-tryptophan-ketoglutarate solution in right lobe adult-to-adult live donor liver transplantation, Liver Transplantation. 2004, 10(11): 1415-1421. |
| Chan S.C., Liu C.L., Lo C.M. and Fan S.T., Primacy of hepatovascular flowmetry in right lobe adult-to-adult live donor liver transplantation (Abstract), The 6th Annual Scientific Meeting, Centre for the Study of Liver Disease, The University of Hong Kong, Hong Kong, 8 January 2005. |
| Chan S.C., Liu C.L., Lo C.M. and Fan S.T., Rapid onset Chilaiditi's sign on top of fulminant hepatic failure (Case Report), Hepatobiliary and Pancreatic Diseases International. 2004, 3(3): 476-477. |
| Chan S.C., Lo C.M., Liu C.L. and Fan S.T., Resurgence of biliary cast syndrome (Images in Liver Transplantation), Liver Transplantation. 2005, 11(2): 242-243. |
| Chan S.Y., Poon R.T.P., Ng K.K.C., Liu C.L., Chan R.T. and Fan S.T., Long-term survival after intraluminal brachytherapy for inoperable hilar cholangiocarcinoma: a case report (Case Report), World Journal of Gastroenterology. 2005, 11(20): 3161-3164. |
| Chan S.Y., Poon R.T.P., Ng K.K.C., Lam C.M. and Fan S.T., Management of carcinoma of gallbladder: a single-institution expereince in 16 years (Abstract), Journal of Gastrointestinal Surgery. 2004, 8(7 Suppl): 68A. |
| Chan S.Y., Poon R.T.P., Ng K.K.C., Lam C.M. and Fan S.T., Management of carcinoma of gallbladder: a single-institution expereince in 16 years (Abstract), The 19th World Congress of Digestive Surgery, Yokohama, Japan, 8-11 December 2004. |
| Chen X., Higgins J., Cheung S.T., Li R., Mason V., Montgomery K., Fan S.T., van de Rijin M. and So S., Novel endothelial cell markers in hepatocellular carcinoma, Modern Pathology. 2004, 17(10): 1198-1210. |
| Cheung S.T., Leung K.L., Ip Y.C., Chen X., Fong D.Y.T., Ng I.O.L., Fan S.T. and So S., Claudin-10 expression level is associated with recurrence of primary hepatocellular carcinoma, Clinical Cancer Research. 2005, 11(2 Pt 1): 551-556. |
| Cheung S.T., Leung K.L., Kwok H.H., Wong S.Y. and Fan S.T., DNALI1 expression and gene polymorphism are associated with disease recurrence after curative surgery in hepatocellular carcinoma (Abstract), The 96th Annual Meeting of the American Association for Cancer Research, Anaheim, California, U.S.A., 16-20 April 2005. |
| Cheung S.T. and Fan S.T., Gene expression profile of hepatocellular carcinoma (Abstract), Asian Journal of Surgery. 2005, 28(Suppl 2): S71. |
| Cheung S.T. and Fan S.T., Gene expression profile of hepatocellular carcinoma (Invited Lecture), The 4th International Meeting on Hepatocellular Carcinoma: Eastern and Western Experiences, Hong Kong, 14-16 December 2004. 2004. |
| Cheung S.T., Wong S.Y., Leung K.L., Chen X., So S., Ng I.O.L. and Fan S.T., Granulin-epithelin precursor (GEP) promotes growth and invasion of hepatocellular carcinoma (Abstract), The 6th Annual Scientific Meeting, Centre for the Study of Liver Disease, The University of Hong Kong, Hong Kong, 8 January 2005. |
| Cheung S.T., Wong S.Y., Leung K.L., Chen X., So S., Ng I.O.L. and Fan S.T., Granulin-epithelin precursor overexpression promotes growth and invasion in hepatocellular carcinoma, Clinical Cancer Research. 2004, 10(22): 7629-7636. |
| Cheung S.T., Ho J.C.Y., Leung K.L., Chen X., Fong D.Y.T., So S. and Fan S.T., Transcript AA454543 is a novel prognostic marker for hepatocellular carcinoma after curative partial hepatectomy, Neoplasia. 2005, 7(2): 91-98. |
| Chiu A., Tam S., Au W.Y., Chan S.C., Liu C.L. and Fan S.T., MARS treatment for a patient presenting with acquired hepatic glutamine synthetase deficiency after orthotopic liver transplantation (Case Report), Liver Transplantation. 2005, 11(3): 353-355. |
| Chok K.S.H., Lam C.M., Li F.K., Ng K.K.C., Poon R.T.P., Lo C.M. and Fan S.T., Management of hepatocellular carcinoma in renal transplant recipients, Journal of Surgical Oncology. 2004, 87(3): 139-142. |
| Chok K.S.H., Yuen W.K., Lau H., Lee F.C.W. and Fan S.T., Outpatient laparoscopic cholecystectomy in Hong Kong Chinese - an outcome analysis, Asian Journal of Surgery. 2004, 27(4): 313-316. |
| Chok K.S.H., Ng K.C.K., Lam C.M., Ng K.K.C., Poon R.T.P. and Fan S.T., Selection portal vein clamping for radiofrequency ablation of hepatocellular carcinoma with portal vein invasion, Journal of Gastrointestinal Surgery. 2005, 9(4): 489-493. |
| Chok S.H., Yuen W.K., Lau H., Lee F.C.W. and Fan S.T., Outpatient laparoscopic cholecystectomy - a review of 135 consecuttive patients (Abstract), Surgical Practice. 2005, 9 (Supplement): S8. |
| Fan S.T., A transplant surgeon's perspective, In: Ethical Issues in Living Donor Liver Transplantation, Workshop of the Clinical Ethics Center, Cochin Hospital, Paris, France, 8 October, 2004. 2005, 31-38. |
| Fan S.T., Adjudicator - Young Investigator Award - Clinical, The 4th International Meeting on Hepatocellular Carcinoma: Eastern and Western Experiences, Hong Kong, 14-16 December 2004. 2004. |
| Fan S.T., Adult-to-adult LDLT (Invited Lecture), Duke University Medical Center, Durham, New Carolina, U.S.A., 18-19 January 2005. 2005. |
| Fan S.T., Adult-to-adult live donor liver transplantation (Invited Lecture), The 2nd Annual McGill University Hepatopancreaticobiliary and Liver Transplant Surgery Symposium, Montreal, Canada, 11-12 November 2004. 2004. |
| Fan S.T., Advisor, The 4th International Meeting of Hepatocellular Carcinoma: Eastern and Western Experiences, Hong Kong, 14-16 December 2004. 2004. |
| Fan S.T., Associate Editor (June 2002 - present), Liver Transplantation . 2005. |
| Fan S.T., Chairperson - Donor issues - technical innovations, International Symposium on Living Donor Organ Transplantation, Essen, Germany, 2-3 September 2004. 2004. |
| Fan S.T., Chairperson - Special topic (2), The 3rd International Symposium on Hepatic Failure and Artificial Liver, Suzhou, China, 24 March 2005. 2005. |
| Fan S.T., Chairperson - Surgical morbidity and ICU treatment, The 2nd International Symposium on Small for Size in Liver Surgery, Ghent, Belgium, 11 March 2005. 2005. |
| Fan S.T., Chairperson, Liver - Hepatitis C, The 3rd International Congress on Immunosuppression, San Diego, U.S.A., 8-11 December 2004. 2004. |
| Fan S.T., Ethical issues of LDLT in Asia – a transplant surgeon's perspective (Invited Lecture), The Centre Ethique Clinique Hospital Cochin Workshop, Paris, France, 8 October 2004. |
| Fan S.T., Interactive Panel Discussion - Ruptured hepatoma: best management, The 8th Postgraduate Course, Selected Liver Diseases: Best Management Options, Penta Hospital Surgical Group, Inc., Manila, Philippines, 19-20 August 2004. |
| Fan S.T., Live donor liver transplantation (Abstract), Asian Journal of Surgery. 2005, 28(Suppl 1): S18. |
| Fan S.T., Live donor liver transplantation (Invited Lecture), The 19th Congress of the Asian Association of Paediatric Surgeons, Hong Kong, 28 November - 1 December 2004. |
| Fan S.T., Live donor liver transplantation and small-for-size graft injury (Invited Lecture), Frontiers in Biomedical Research – Clinical Application, Beiing, China, 6 December 2004. |
| Fan S.T., Live related liver transplant - pro (Invited Lecture), The 14th Biennial Conference of the Asian Pacific Association for the Study of the Liver, New Delhi, India, 11-15 December 2004. 2004. |
| Fan S.T., Liver resection in cirrhosis: the best predictor of liver function post resection (Invited Lecture), The 8th Postgraduate Course, Selected Liver Diseases: Best Management Options, Penta Hospital Surgical Group, Inc, Manila, Philippines, 19-20 August 2004. |
| Fan S.T., Liver resections: how I do it? (Invited Lecture), The 8th Postgraduate Course, Selected Liver Diseases: Best Management Options, Penta Hospital Surgical Group, Inc, Manila, Philippines, 19-20 August 2004. |
| Fan S.T., Liver tranplantation for acute on chronic liver failure (Invited Lecture), The 3rd International Symposium on Hepatic Failure and Artificial Liver, Suzhou, China, 24 March 2005. |
| Fan S.T., Liver transplantation for HBV patients (Invited Lecture), The Koichi Tanaka Symposium on Liver Transplantation, Kyoto, Japan, 3 April 2005. 2005. |
| Fan S.T., Liver transplantation in Hong Kong (Invited Lecture), The 1st Symposium of the Chinese Hepato-Pancreato-Biliary Chapter of the International Hepato-Pancreato-Biliary Association and The 2nd National Congress of Chief Surgeons in General Surgery, Wuhan, China, 3-6 December 2004. |
| Fan S.T., Liver transplantation in Hong Kong (Invited Lecture), The 9th Hong Kong Medical Forum, Department of Medicine, Faculty of Medicine, the University of Hong Kong, Hong Kong, 17-18 July 2004. |
| Fan S.T., Member of Editorial Board, 消化外科, 2005. |
| Fan S.T., Member of Editorial Board (1991 - present), Journal of Gastroenterology and Hepatology. 2005. |
| Fan S.T., Member of Editorial Board (1995 - present), Hepato-Gastroenterology. 2005. |
| Fan S.T., Member of Editorial Board (1998 - present), Archives of Surgery. 2005. |
| Fan S.T., Member of Editorial Board (2001 - present), 中國肝癌雜誌, 2005. |
| Fan S.T., Member of Editorial Board (December 1998 - present), Nutrition. 2005. |
| Fan S.T., Member of Editorial Board (December 2002 - present), 中國普外基礎與臨床雜誌, 2005. |
| Fan S.T., Member of Editorial Board (December 2003 - present), 中華外科治療學雜誌, 2005. |
| Fan S.T., Member of Editorial Board (December 2003 - present), 移植雜誌, 2005. |
| Fan S.T., Member of Editorial Board (January 1993 - present), Hong Kong Practitioner. 2005. |
| Fan S.T., Member of Editorial Board (January 1999 - present), 中華普通外科雜誌, 2005. |
| Fan S.T., Member of Editorial Board (January 2000 - present), 中華醫學雜誌, 2005. |
| Fan S.T., Member of Editorial Board (January 2000 - present), Asian Journal of Surgery. 2005. |
| Fan S.T., Member of Editorial Board (January 2000 - present), Journal of Hepatobiliary Pancreatic Surgery (Japan). 2005. |
| Fan S.T., Member of Editorial Board (January 2005 - present), Current Nutrition and Food Science. 2005. |
| Fan S.T., Member of Editorial Board (January 2005 - present), Transplantation. 2005. |
| Fan S.T., Member of Editorial Board (July 1999 - present), HPB. 2005. |
| Fan S.T., Member of Editorial Board (July 2001 - present), 中國實用外科雜誌, 2005. |
| Fan S.T., Member of Editorial Board (May 1998 - present), 中華肝膽外科雜誌, 2005. |
| Fan S.T., Member of Editorial Board (October 1999 - present), Digestive Surgery. 2005. |
| Fan S.T., Member of Editorial Board (October 2001 - present), Hepatobiliary and Pancreatic Diseases International. 2005. |
| Fan S.T., Member of Editorial Board (October 2004 - present), World Journal of Gastroenterology. 2005. |
| Fan S.T., Member of Editorial Board, British Journal of Surgery. 2005. |
| Fan S.T., Member of Editorial Board, Journal of Cancer Research and Clinical Oncology. 2005. |
| Fan S.T., Member of Liver Editorial Board, The 3rd International Congress on Immunosuppression, San Diego, U.S.A., 8-11 December 2004 . 2004. |
| Fan S.T., New strategies for management of hepatocellular carcinoma (Invited Lecture), The 6th Symposium on Liver Disease, Association for the Study of the Liver, Dhaka, Bangladesh, Dhaka, India, 1 December 2004. |
| Fan S.T., Overview of recipient surgical techniques and outcomes in adult LDLT (Invited Lecture), The 14th Biennial Conference of the Asian Pacific Association for the Study of the Liver, New Delhi, India, 12 December 2004. 2004. |
| Fan S.T., Protection of liver remnant during partial hepatectomy (Invited Lecture), The 2nd Annual McGill University Hepatopancreaticobiliary and Liver Transplant Surgery Symposium, Montreal, Canada, 11-12 November 2004. 2004. |
| Fan S.T., Protection of liver remnant in partial hepatectomy (Invited Lecture), Duke University Medical Center, Durham, New Carolina, U.S.A., 18-19 January 2005. 2005. |
| Fan S.T., Protection of the liver during partial hepatectomy (Review Article), Hepatobiliary and Pancreatic Diseases International . 2004, 3(4): 490-494. |
| Fan S.T., Reducing blood loss in liver surgery: strategies (Invited Lecture), The 14th Biennial Conference of the Asian Pacific Association for the Study of the Liver, New Delhi, India, 11-15 December 2004. 2004. |
| Fan S.T., Resecting HCC in a cirrhotic liver (Invited Lecture), The 14th Biennial Conference of the Asian Pacific Association for the Study of the Liver, New Delhi, India, 11-15 December 2004. 2004. |
| Fan S.T., Right lobe LDLT - the University of Hong Kong experience (Abstract), The Centre for Liver Disease and Transplantation of the New York Presbyterian Hospital, Columbia University College of Physicians and Surgeons, New York, U.S.A., 18 May 2005. 2005. |
| Fan S.T., The best treatment for HCC - perspective from University of Hong Kong (Invited Lecture), The 59th Annual Meeting of the Japanese Society of Gastroenterological Surgery, Kagoshima, Japan, 21-23 July 2004. |
| Fan S.T., The outflow reconstruction in LDLT (Invited Lecture), The 2nd International Symposium on Small for Size in Liver Surgery, Ghent, Belgium, 11 March 2005. 2005. |
| Fan S.T., Use of MARS dialysis in patients with liver failure in Hong Kong (Abstract), The 3rd International Symposium on Hepatic Failure and Artificial Liver, Suzhou, China, 24-27 March 2005. |
| Fan S.T., 右葉活體肝移植的膽道併發症及其預防方法 (Invited Lecture), 中國福州第十一屆全國膽道外科學術會議, 2004年11月3-7日, 2004. |
| Fan S.T., 成人右肝活體肝移植術 (Invited Lecture), 中國西安第二屆全國器官移植學術會議, 2004年10月14-15日, 2004. |
| Fan S.T. and Cai C., 如何獲取最佳肝切除術結果 (Invited Lecture), 中國成都第七屆全國普通外科中青年醫師學術交流會暨第十屆全國普通外科學術會議, 2004年9月23日, 2004. |
| Fan S.T., 肝移植前沿與爭論問題 (Invited Lecture), 中國武漢中國臨床普外科前沿與爭論高峰論壇, 2004年11月26-28日, 2004. |
| Fan S.T., 肝移植臨床新進展 (Invited Lecture), 中國天津全國臨床肝移植研討會, 2004年12月19日, 2004. |
| Fan S.T., 成人右肝活體肝移植術 (Invited Lecture), 中國沈陽中華醫學會全國器官移植學術會議, 2004年8月27-30日, 2004. |
| Fan S.T. and Chiu A., 肝移植術後病人的肝臟支持治療 (Invited Lecture), 中國蘇州第二屆國際MARS專題小組會—亞洲MARS臨床,2005年3月24日, 2005. |
| Ho D.W.Y., Luk J.M.C. and Fan S.T., Plasma proteomic profiling and identification of circulating biomarkers for monitoring fulminant hepatic failure in a porcine model (Abstract), HUPO 3rd Annual World Congress, Beijing, China, 25-27 October 2004. |
| Ho D.W.Y., Luk J.M.C. and Fan S.T., Plasma proteomic profiling and identification of circulating biomarkers for monitoring fulminant hepatic failure, Molecular and Cellular Proteomics. 2004, 3(10): S112, 8.14. |
| Ho D.W.Y., Yang Z., Lau C.K., To J.Y.T., Luk J.M.C. and Fan S.T., The therapeutic role of cardiotrophin-1 in a rat model with fulminant hepatic failure (Abstract), The 6th Annual Scientific Meeting, Centre for the Study of Liver Disease, The University of Hong Kong, Hong Kong, 8 January 2005. |
| Ho J.C.Y., Cheung S.T., Leung K.L., Ng I.O.L. and Fan S.T., Decreased expression of cytochrome P450 2E1 is associated with poor prognosis of hepatocellular carcinoma, International Journal of Cancer. 2004, 111(4): 494-500. |
| Ho J.C.Y., Cheung S.T. and Fan S.T., Up-regulation of glycosylphatidylinositols anchor attachment protein (GAA1), a novel oncogene, in hepatocellular carcinoma (Abstract), Asian Journal of Surgery. 2005, 28(Suppl 2): S89. |
| Ho J.C.Y., Cheung S.T. and Fan S.T., Up-regulation of glycosylphatidylinositols anchor attachment protein (GAA1), a novel oncogene, in hepatocellular carcinoma (Abstract), The 4th International Meeting on Hepatocellular Carcinoma: Eastern and Western Experiences, Hong Kong, 14-16 December 2004. |
| Ho J.C.Y., Cheung S.T. and Fan S.T., Up-regulation of glycosylphatidylinositols anchor attachment protein 1 (GAA1), a novel oncogene, in hepatocellular carcinoma (Abstract), The 6th Annual Scientific Meeting, Centre for the Study of Liver Disease, The University of Hong Kong, Hong Kong, 8 January 2005. |
| Ho J.W.Y., Poon R.T.P., Tong C.S.W. and Fan S.T., Clinical significance of serum vascular cell adhesion molecule-1 levels in patients with hepatocellular carcinoma, World Journal of Gastroenterology. 2004, 10(14): 2014-2018. |
| Ho J.W.Y., Poon R.T.P., Sun K.W., Xue W.C. and Fan S.T., Clinicopathological and prognostic implications of endoglin (CD105) expression in hepatocellular carcinoma and its adjacent non-tumorous liver, World Journal of Gastroenterology. 2005, 11(2): 176-181. |
| Ho J.W.Y., Man K., Sun K.W., Poon R.T.P. and Fan S.T., Effective low dose combined-drug treatment using FTY720 and Gleeve in hepatocellular carcinoma (Abstract), The 6th Annual Scientific Meeting, Centre for the Study of Liver Disease, The University of Hong Kong, Hong Kong, 8 January 2005. |
| Ho J.W.Y., Man K., Sun K.W., Poon R.T.P. and Fan S.T., Effective low dose combined-drug treatment using FTY720 and Gleevec in hepatocellular carcinoma (Abstract), Asian Journal of Surgery. 2005, 28(Suppl 2): S82. |
| Ho J.W.Y., Man K., Sun K.W., Poon R.T.P. and Fan S.T., Effective low dose combined-drug treatment using FTY720 and Gleevec in hepatocellular carcinoma (Abstract), The 4th International Meeting on Hepatocellular Carcinoma: Eastern and Western Experiences, Hong Kong, 14-16 December 2004. |
| Ku C.F., Lo C.Y., Chan W.F., Chiu S.W., Fan S.T. and Lam K.S.L., Resection of phaeochromocytoma extending into the right atrium in a patient with multiple endocrine neoplasia type 2A, Hong Kong Medical Journal. 2005, 11(1): 59-62. |
| Lam C.M., Yuen A.W., Wai A.C., Leung R.M., Lee A.Y., Ng K.K.C. and Fan S.T., Gallbladder cancer presenting with acute cholecystitis: a population-based study, Surgical Endoscopy. 2005, 19(5): 697-701. |
| Lam C.M., Fan S.T., Yuen A. and Wai A., Institutional volume determines the outcome of non-pancreatic periampullary lesions after pancreaticoduodenectomy (Abstract), HPB. 2005, 7(1 Suppl): 111. |
| Lam C.M., Ng K.K.C., Poon R.T.P., Yuen H.F. and Fan S.T., Thoracoscopic RFA (Abstract), Asian Journal of Surgery. 2005, 28(Suppl 2): S77. |
| Lam C.M., Ng K.K.C., Poon R.T.P., Yuen H.F. and Fan S.T., Thoracoscopic RFA (Invited Lecture), The 4th International Meeting on Hepatocellular Carcinoma: Eastern and Western Experiences, Hong Kong, 14-16 December 2004. |
| Lang B.H.H., Poon R.T.P., Fan S.T. and Wong J., Outcomes of patients with hepatocellular carcinoma presenting with variceal bleeding, American Journal of Gastroenterology. 2004, 99(11): 2158-2165. |
| Lee K.W., Man K., Poon R.T.P., Lo C.M., Ng I.O.L. and Fan S.T., Disruption of p53-p21/WAF1 cell cycle pathway contributes to progression and worse clinical outcome of hepatocellular carcinoma, Oncology Reports. 2004, 12(1): 25-31. |
| Lee K.W., Man K., Ho J.W.Y., Sun K.W., Ng T.P., Wang X., Wong Y.C., Ng I.O.L., Xu R. and Fan S.T., FTY720 induces apoptosis of human hepatoma cell lines through PI3-K-mediated Akt dephosphorylation, Carcinogenesis. 2004, 25(12): 2397-2405. |
| Lee K.W., Man K. and Fan S.T., Significance of Rac signaling pathway in HCC cell motility: implication for a new therapeutic treatment (Abstract), Asian Journal of Surgery. 2005, 28(Suppl 2): S90. |
| Lee K.W., Man K. and Fan S.T., Significance of Rac signaling pathway in HCC cell motility: implication for a new therapeutic treatment (Abstract), The 4th International Meeting on Hepatocellular Carcinoma: Eastern and Western Experiences, Hong Kong, 14-16 December 2004. |
| Lee K.W., Man K. and Fan S.T., Significance of Rac signaling pathway in hepatocellular carcinoma cell motility: implication for a new therapeutic treatment by FTY720 (Abstract), The 6th Annual Scientific Meeting, Centre for the Study of Liver Disease, The University of Hong Kong, Hong Kong, 8 January 2005. |
| Lee K.W., Man K., Ho J.W.Y., Wang X., Poon R.T.P., Sun K.W., Ng T.P., Ng I.O.L., Xu R. and Fan S.T., Significance of the Rac signaling pathway in HCC cell motility: implications for a new therapeutic target, Carcinogenesis. 2005, 26(3): 681-687. |
| Leung T.M., Fan S.T., Liong E.C., Fung M.L., Lau T.Y.H., Leung K.M., Tom W.M., Nanji A.A. and Tipoe G.L., Nitric oxide and fibrotic factors in chronic liver injury (Abstract), The 6th Annual Scientific Meeting, Centre for the Study of Liver Disease, The University of Hong Kong, Hong Kong, 8 January 2005. |
| Leung T.M., Tipoe G.L., Lau T.H.Y., Liong E.C., So H., Leung K.M., Leung W.M., Tom W.M., Fung M.L., Fan S.T. and Nanji A.A., Nitric oxide in an acute liver injury model, Society of Pathology Meeting, 2005 Journal of Pathology, Suppl. . 2005, 205: 11-11. |
| Li X.L., Man K., Ng K.T., Lee T.K.W., Lo C.M. and Fan S.T., Insulin in UW solution exacerbates hepatic ischemia/reperfusion injury by energy depletion through IRS-2/SREBP-1c pathway, Liver Transplantation. 2004, 10(9): 1173-1182. |
| Li X.L., Man K., Ng T.P., Sun K.W., Lo C.M. and Fan S.T., The influence of phosphatidylinositol 3-kinase/Akt pathway on the ischemic injury during rat liver graft preservation, American Journal of Transplantation. 2005, 5(6): 1264-1275. |
| Lin C.L., Fan S.T., Lo C.M. and Wong J., The role of endoscopic ultrasonography in the management of acute pancreatitis: a prospective randomized study (Invited Lecture), The 12th United European Gastroenterology Week, Prague, Czech Republic, 25-29 September 2004. |
| Liu C.L., Fan S.T., Lo C.M. and Wong J., Clinicobiochemical prediction of biliary cause for acute pancreatitis in the era of endoscopic ultrasonography (Poster Presentation), The 12th United European Gastroenterology Week, Prague, Czech Republic, 25-29 September 2004. |
| Liu C.L., Fan S.T., Lo C.M., Chan S.C., Tso W.K., Ng I.O.L. and Wong J., Hepatic resection for incidentaloma, Journal of Gastrointestinal Surgery. 2004, 8(7): 785-793. |
| Liu C.L., Fan S.T., Lo C.M., Tso W.K. and Wong J., Improved operative and survival outcomes of surgical treatment for hilar cholangiocarcinoma (Abstract), HPB. 2005, 7(1 Suppl): 129. |
| Liu C.L., Fan S.T., Lo C.M., Tso W.K. and Wong J., Improved operative and survival outcomes of surgical treatment for hilar cholangiocarcinoma (Invited Lecture), The 6th Congress of the European Hepato-Pancreato-Biliary Association, Heidelberg, Germany, 25-28 May 2005. |
| Liu C.L., Fan S.T., Lo C.M., Wei W.I., Chan S.C., Yong B.H., Lai C.L. and Wong J., Operative outcomes of adult-to-adult right lobe live donor liver transplantation: a comparative study with cadaveric whole-graft liver transplantation in a single center (Abstract), The 20th International Congress of the Transplantation Society, Vienna, Austria, 5-10 September 2004. |
| Liu C.L., Fan S.T., Lo C.M., Chan S.C., Yong B.H. and Wong J., Safety of donor right hepatectomy without abdominal drainage: a prospective evaluation in 100 consecutive liver donors, Liver Transplantation. 2005, 11(3): 314-319. |
| Liu Y., Poon R.T.P. and Fan S.T., Antitumor activity of epidermal growth factor receptor tyrosine kinase Inhibitors in human hepatocellular carcinoma cell lines (Abstract), The 44th American Society For Cell Biology Annual Meeting, Washington D.C., U.S.A., December 4-8 2004. |
| Liu Y., Poon R.T.P., Shao W. and Fan S.T., Antitumour activity of epidermal growth factor receptor tyrosine kinase inhibitors in human hepatocellular carcinoma (Abstract), Asian Journal of Surgery. 2005, 28(Suppl 2): S90. |
| Liu Y., Poon R.T.P., Shao W. and Fan S.T., Antitumour activity of epidermal growth factor receptor tyrosine kinase inhibitors in human hepatocellular carcinoma (Abstract), The 4th International Meeting on Hepatocellular Carcinoma: Eastern and Western Experiences, Hong Kong, 14-16 December 2004. |
| Liu Y., Poon R.T.P. and Fan S.T., Blockage of vascular endothelial growth factor receptors by tyrosine kinase inhibitor PTK787/ZK222584 inhibits growth of hepatocellular carcinoma with metastatic potential by angiogenesis-independent effect (Abstract), The 96th Cancer Research Annual Meeting, Anaheim, California, U.S.A., 16-20 April 2005. |
| Liu Y., Poon R.T.P., Li Q., Kok T.W., Lau C.P.Y. and Fan S.T., Both antiangiogenesis- and angiogenesis-independent effects are responsible for hepatocellular carcinoma growth arrest by tyrosine kinase inhibitor PTK787/ZK222584, Cancer Research. 2005, 65(9): 3691-3699. |
| Liu Y., Poon R.T.P., Hughes J., Feng X., Yu W.C. and Fan S.T., Chemokine receptors support infiltration of lymphocyte subpopulations in human hepatocellular carcinoma, Clinical Immunology. 2005, 114(2): 174-182. |
| Liu Y., Poon R.T.P., Hughes J., Li Q.Y., Yu W.C. and Fan S.T., Desensitization of T lymphocyte function by CXCR3 ligands in human hepatocellular carcinoma, World Journal of Gastroenterology. 2005, 11(2): 164-170. |
| Lo C.M., Liu C.L. and Fan S.T., Correction of left hepatic vein redundancy in paediatric liver transplantation, Asian Journal of Surgery. 2005, 28(1): 55-57. |
| Lo C.M., Fan S.T., Liu C.L., Yong B.H., Wong Y., Lau G., Lai C.L., Ng I.O.L. and Wong J., Lessons learned from one hundred right lobe living donor liver transplants, Annals of Surgery. 2004, 240(1): 151-158. |
| Lo C.M., Liu C.L., Lau G., Chan S.C., Ng I.O.L., Fan S.T. and Wong J., Liver transplantation for chronic hepatitis B with lamivudine-resistant YMDD mutant using add-on adefovir dipivoxil to lamivudine (Abstract), American Journal of Transplantation. 2005, 5(Suppl): 180. |
| Lo C.M., Liu C.L., Lau G., Chan S.C., Ng I.O.L., Fan S.T. and Wong J., Liver transplantation for chronic hepatitis B with lamivudine-resistant YMDD mutant using add-on adefovir dipivoxil to lamivudine (Poster Presentation), American Transplant Congress, Seattle, U.S.A., 21-25 May 2005. |
| Lo C.M., Fan S.T., Liu C.L., Chan S.C., Ng I.O.L. and Wong J., Living donor versus deceased donor liver transplantation for early unresectable hepatocellular carcinoma: same criteria, different outcome (Abstract), HPB. 2005, 7(1 Suppl): 54. |
| Lo C.M., Fan S.T., Liu C.L., Chan S.C., Ng I.O.L. and Wong J., Living donor versus deceased donor liver transplantation for early unresectable hepatocellular carcinoma: same criteria, different outcome (Invited Lecture), The 6th Congress of the European Hepato-Pancreato-Biliary Association, Heidelberg, Germany, 25-28 May 2005. |
| Lo C.M., Fan S.T. and Wong J., Living donor versus deceased donor liver transplantation for early unresectable hepatocellular carcinoma: same criteria, different outcome (Poster Presentation), Digestive Disease Week, Chicago, U.S.A., 14-19 May 2005. |
| Lo C.M., Fan S.T., Liu C.L., Chan S.C., Ng I.O.L. and Wong J., Living donor versus deceased donor liver transplantation for small unresectable hepatocellular carcinoma: same criteria, different outcome (Invited Lecture), The 6th Annual Scientific Meeting, Centre for the Study of Liver Disease, The University of Hong Kong, Hong Kong, 8 January 2005. |
| Luk J.M.C., Lam B.Y.H., Yi X., Peng J., Leng X. and Fan S.T., Applicability of proteomic biomarkers set to distinguish hepatocellular carcinoma from non-tumor and healthy liver tissues, 4th HUPO Annual Congress, Munich, Germany, 28 August - 1 September 2005. |
| Luk J.M.C., Lam B.K.Y., Yi X., Peng J., Leng X. and Fan S.T., Applicability of proteomic biomarkers set to distinguish hepatocellular carcinoma from non-tumor and healthy liver tissues, Molecular and cellular proteomics. 2005, 4(8) suppl. 13.55: S119. |
| Luk J.M.C. and Fan S.T., Applicability of proteomic biomarkers set to distinguish hepatocellular carcinoma from non-tumor and healthy liver tissues, The XXL Symposium on Molecular Control of Cancer, Cold Spring Harbor Lab, New York, U.S.A., 1-5 June 2005. |
| Luk J.M.C., Lam C.T., Lam B.H., Siu A., Che C.M. and Fan S.T., Dyregulation of chaperone proteins Hsp27, Hsp70 and Grp78 in hepatocellular carcinoma (Abstract), The 3rd HUPO Annual World Congress, Beijing, China, 25-27 October . 2004. |
| Luk J.M.C., Lam C.T., Lam B.H., Siu A., Che C.M. and Fan S.T., Dysregulation of chaperone proteins Hsp27, Hsp70 and Grp78 in hepatocellular carcinoma, Molecular and Cellular Proteomics. 2004, 3(10): S114, 8.19. |
| Luk J.M.C., Lee N.P., Ma J. and Fan S.T., Expression of recombinant integrin b2 subunit that ameliorate LPS binding activity to endothelial cell, FASEB Annual Meeting EB/IUPS Conference, San Diego, U.S.A., 21 March - 6 April 2005. |
| Luk J.M.C., Lee N.P., Klickstein L.B. and Fan S.T., Generation and application of anti-CD18mAb and Fv derivatives for preventing LPS-activated leukocyte adhesion, The Protein Engineering Summit: Phage display, recombinant antibody, and monoclonal antibody, Cambridge Health Institute, Boston, U.S.A., 16 - 20 May 2005. |
| Luk J.M.C., Wang P., Wang J. and Fan S.T., Hepatic potential of bone marrow stromal cells after co-culture with damaged liver tissues and intraportal transplantation in cirrhotic liver, The 34th Annual Scientific Meeting of the Australasian Society for Immunology and 8th International Conference on Human Leucocyte Differentiation Antigens (HLDA8), Adelaide, Australia, 12-16 December 2004. |
| Luk J.M.C., Wang P., Wang J., Lau G. and Fan S.T., Hepatocyte-like phenotypes of bone marrow stromal cells after co-culture with damaged liver tissues and intraportal transplantation in cirrhotic liver (Abstract), The 55th Annual Meeting of the American Association for the Study of Liver Diseases, Boston, USA, 29 October – 2 November 2004. |
| Luk J.M.C., Wang P.P., Wang J., Lau G.K. and Fan S.T., Hepatocyte-like phenotypes of bone marrow stromal cells after co-culture with damaged liver tissues and intraportal transplantation in cirrhotic liver, Hepatology. 2004, 40 (Supplement 1): LB-16, 733A. |
| Luk J.M.C., Peng J.R., Leng X.S. and Fan S.T., Molecular classification of hepatocellular carcinoma by proteomic expression profiling (Abstract), HUPO 3rd Annual World Congress, Beijing, China, 25-27 October 2004. |
| Luk J.M.C., Lam B.K.Y., Lam C.T., Siu F.M., Ho D.W.Y., Yu W.C., Peng J.R., Che C.M., Leng X.S. and Fan S.T., Molecular classification of hepatocellular carcinoma by proteomic expression profiling (Abstract), The 6th Annual Scientific Meeting, Centre for the Study of Liver Disease, The University of Hong Kong, Hong Kong, 8 January 2005. |
| Luk J.M.C., Peng J.R., Leng X.S. and Fan S.T., Molecular classification of hepatocellular carcinoma by proteomic expression profiling, Molecular and Cellular Proteomics. 2004, 3(10): S144, 8.18. |
| Luk J.M.C., Lee C.K.F., Su Y.C.F., Lam C.T., Hu M.Y., He Q., Lau G., Wong W.S. and Fan S.T., Proteomic identification of Ku70/Ku80 autoantigen recognized by monoclonal antibody against hepatocellular carcinoma (Abstract), HUPO 3rd Annual World Congress, Beijing, China, 25-27 October 2004. |
| Luk J.M.C., Su Y.C.F., Lam C.T., Lee C.K.F., Hu M.Y., He Q., Lau G., Wong F.W.S. and Fan S.T., Proteomic identification of Ku70/Ku80 autoantigen recognized by monoclonal antibody against hepatocellular carcinoma, Proteomics. 2005, 5(7): 1980-1986. |
| Luk J.M.C., Cheung N., Lam B.Y.H. and Fan S.T., Proteomic roadmap of mouse liver development from embryo to adult, Molecular and cellular proteomics. 2005, 4(8) Suppl 8.3: S77. |
| Luk J.M.C., Cheung N., Lam B.K.Y. and Fan S.T., Proteomic roadmap of mouse liver development from embryo to adult, The 4th HUPO Annual Congress, Munich, Germany, 28 August - 1 September 2005. |
| Luk J.M.C., Lee C.K.F., Wang X. and Fan S.T., Recognition of monoclonal antibodies against alternative splicing of liver intestine cadherin (Cdh17) in hepatocellular carcinoma , The 34th Annual Scientific Meeting of the Australasian Society for Immunology and 8th International Conference on Human Leucocyte Differentiation Antigens (HLDA8), Adelaide, Australia, 12-16 December 2004. |
| Luo Y., Lo C.M., Cheung C.K.Y., Lau G. and Fan S.T., Identification of hepatitis B virus specific lymphocytes in human liver allografts from hepatitis B virus immune donors (Abstract), The 6th Annual Scientific Meeting, Centre for the Study of Liver Disease, The University of Hong Kong, Hong Kong, 8 January 2005. |
| Luo Y., Lo C.M., Cheung C.K.Y., Lau G., Fan S.T. and Wong J., Potential role of resident intrahepatic lymphocytes in adoptive transfer of immunity to hepatitis B virus through liver transplantation (Poster Presentation), Digestive Disease Week, Chicago, U.S.A., 14-19 May 2004. |
| Man K., Lee K.W., Liang T.B., Lo C.M., Fung P.C.W., Tsui H.T., Li X.L., Ng T.P. and Fan S.T., FK409 ameliorates small-for-size liver graft injury by attenuation of portal hypertension and down-regulation of Egr-1 pathway, Annals of Surgery. 2004, 240(1): 159-168. |
| Man K., Ng T.P., Lee K.W., Lo C.M., Sun K.W., Li X., Zhao Y., Ho J.W.Y. and Fan S.T., FTY720 attenuates hepatic ischemia-reperfusion injury in normal and cirrhotic livers, American Journal of Transplantation. 2005, 5(1): 40-49. |
| Man K., Ng T.P., Lo C.M., Sun K.W., Zhao Y., Ho J.W.Y., Lee K.W. and Fan S.T., Hepatic I/R injury on small liver remnant promotes liver tumor growth and metastasis - activation of cell invasion and migration pathways (Abstract), The 20th International Congress of the Transplantation Society, Vienna, Austria, 5-10 September 2004. |
| Man K., Ng T.P. and Fan S.T., Hepatic I/R injury on small liver remnant promotes liver tumour growth and metastasis - activation of cell invasion and migration pathway (Abstract), The 4th International Meeting on Hepatocellular Carcinoma: Eastern and Western Experiences, Hong Kong, 14-16 December 2004. |
| Man K., Ng T.P. and Fan S.T., Hepatic I/R injury on small liver remnant promotes liver tumour growth and metastasis - activation of cell invasion and mirgration pathway (Abstract), Asian Journal of Surgery. 2005, 28(Suppl 2): S83. |
| Man K., Xu A., Xu A., Zhao Y., Lo C.M., Ng T.P., Sun K.W. and Fan S.T., Rescue of small-for-size fatty liver grafts injury by FTY720 and adiponectin combination therapy (Abstract), The 20th International Congress of the Transplantation Society, Vienna, Austria, 5-10 September 2004. |
| Ng K., Lam C.M., Liu C.L. and Fan S.T., Surgical treatment of colorectal liver metastases (Abstract), The 6th Annual Scientific Meeting, Centre for the Study of Liver Disease, The University of Hong Kong, Hong Kong, 8 January 2005. |
| Ng K.K.C., Poon R.T.P., Lam C.M., Yuen J., Tso W.K. and Fan S.T., Comparison of radiofrequency ablation and transarterial chemoembolization for unresectable hepatocellular carcinoma (Abstract), Journal of Gastrointestinal Surgery. 2004, 8(7 Suppl): 325A. |
| Ng K.K.C., Poon R.T.P., Lam C.M., Yuen J., Tso W.K. and Fan S.T., Comparison of radiofrequency ablation and transarterial chemoembolization for unresectable hepatocellular carcinoma (Poster Presentation), The 19th World Congress of Digestive Surgery, Yokohama, Japan, 8-11 December 2004. |
| Ng K.K.C., Lam C.M., Poon R.T.P., Shek T.W.H., To J.Y.T., Wo Y.H., Ho D.W.Y. and Fan S.T., Comparison of systemic responses of radiofrequency ablation, cryotherapy, and surgical resection in a porcine liver model, Annals of Surgical Oncology. 2004, 11(7): 650-657. |
| Ng K.K.C., Poon R.T.P., Lam C.M. and Fan S.T., Initial experience of radiofrequency ablation for ruptured hepatocellular carcinoma (Abstract), Asian Journal of Surgery. 2005, 28(Suppl 2): S93. |
| Ng K.K.C., Poon R.T.P., Lam C.M. and Fan S.T., Initial experience of radiofrequency ablation for ruptured hepatocellular carcinoma (Abstract), Journal of Gastrointestinal Surgery. 2004, 8(7 Suppl): 151A. |
| Ng K.K.C., Poon R.T.P., Lam C.M. and Fan S.T., Initial experience of radiofrequency ablation for ruptured hepatocellular carcinoma (Abstract), The 19th World Congress of Digestive Surgery, Yokohama, Japan, 8-11 December 2004. |
| Ng K.K.C., Poon R.T.P., Lam C.M. and Fan S.T., Initial experience of radiofrequency ablation for ruptured hepatocellular carcinoma (Abstract), The 4th International Meeting on Hepatocellular Carcinoma: Eastern and Western Experiences, Hong Kong, 14-16 December 2004. |
| Ng K.K.C., Vauthey J.N., Pawlik T.M., Lauwers G.Y., Regimbeau J.M., Belghiti J., Ikai I., Yamaoka Y., Curley S.A., Nagorney D.M., Ng I.O.L., Fan S.T. and Poon R.T.P., Is hepatic resection for large or multinodular hepatocellular carcinoma justified? Results from a multi-institutional database (Abstract), Asian Journal of Surgery. 2005, 28(Suppl 2). |
| Ng K.K.C., Vauthey J.N., Pawlik T.M., Lauwers G.Y., Regimbeau J.M., Belghiti J., Ikai I., Yamaoka Y., Curley S.A., Nagorney D.M., Ng I.O.L., Fan S.T. and Poon R.T.P., Is hepatic resection for large or multinodular hepatocellular carcinoma justified? Results from a multi-institutional database (Abstract), The 4th International Meeting on Hepatocellular Carcinoma: Eastern and Western Experiences, Hong Kong, 14-16 December 2004. |
| Ng K.K.C., Vauthey J.N., Pawlik T.M., Lauwers G.Y., Regimbeau J.M., Belghiti J., Ikai I., Yamaoka Y., Curley S.A., Nagorney D.M., Ng I.O.L., Fan S.T. and Poon R.T.P., Is hepatic resection for large or multinodular hepatocellular carcinoma justified? Results from a multi-institutional database, Annals of Surgical Oncology. 2005, 12(5): 364-373. |
| Ng K.K.C., Lam C.M., Poon R.T.P., Shek T.W.H., Ho D.W.Y. and Fan S.T., Maximal host tolerance to large-volume hepatic radiofrequency ablation in a rat model (Abstract), Journal of Gastrointestinal Surgery. 2004, 8( 7 Suppl): 114A. |
| Ng K.K.C., Lam C.M., Poon R.T.P., Shek T.W.H., Ho D.W.Y. and Fan S.T., Maximal host tolerance to large-volume hepatic radiofrequency ablation in a rat model (Abstract), The 19th World Congress of Digestive Surgery, Yokohama, Japan, 8-11 December 2004. |
| Ng K.K.C., Lam C.M., Poon R.T.P., Shek T.W.H., Yu W.C., To J.Y.T., Wo Y.H., Lau C.P.Y., Tang T.C.M., Ho D.W.Y. and Fan S.T., Porcine liver: morphological characteristics and cell viability at experimental radiofrequency ablation with internally cooled electrodes, Radiology. 2005, 235(2): 478-486. |
| Ng K.K.C., Poon R.T.P., Lam C.M., Yuen J., Tso W.K. and Fan S.T., Safety and efficacy of radiofrequency ablation for perivascular hepatocellular carcinoma without hepatic inflow occlusion (Abstract), The 6th Annual Scientific Meeting, Centre for the Study of Liver Disease, The University of Hong Kong, Hong Kong, 8 January 2005. |
| Ng K.K.C., Poon R.T.P., Lam C.M., Yuen J., Tso W.K. and Fan S.T., Safety and efficacy of radiofrequency ablation for perivascular hepatocellular carcinoma without inflow occlusion (Abstract), Journal of Gastrointestinal Surgery. 2004, 8(7 Suppl): 115A. |
| Ng K.K.C., Poon R.T.P., Lam C.M., Yuen J., Tso W.K. and Fan S.T., Safety and efficacy of radiofrequency ablation for perivascular hepatocellular carcinoma without inflow occlusion (Abstract), The 19th World Congress of Digestive Surgery, Yokohama, Japan, 8-11 December 2004. |
| Ng S.M., Gao Y., Lum C.T., Yang Z.F., Huang J., Lau G., Fan S.T., Kung H. and Lin M.C., Novel gene therapy by rAAV-mediated transfer of human TERTC27 polypeptide in human and rat hepatocellular carcinomas, American Association for Cancer Research Meeting. 2004. |
| Ng S.S., Gao Y., Lum C.T., Yang Z., Huang J., Lau G., Fan S.T., Kung H. and Lin M.C., Novel HCC gene therapy by rAAV-mediated transfer of human TERTC27 polypeptide in human and rat hepatocellular carcinoma (Abstract), Asian Journal of Surgery. 2005, 28(Suppl 2): S99. |
| Ng S.S., Gao Y., Lum C.T., Yang Z., Huang J., Lau G., Fan S.T., Kung H. and Lin M.C., Novel HCC gene therapy by rAAV-mediated transfer of human TERTC27 polypeptide in human and rat hepatocellular carcinoma (Abstract), The 4th International Meeting on Hepatocellular Carcinoma: Eastern and Western Experiences, Hong Kong, 14-16 December 2004. |
| Ng S.S., Gao Y., Lum C.T., Yang Z., Lau G., Fan S.T., Kung H. and Lin M.C., rAAV-mediated long-term expression of endostatin significantly inhibits the progression of HCC (Abstract), Asian Journal of Surgery. 2005, 28(Suppl 2): S100. |
| Ng S.S., Gao Y., Lum C.T., Yang Z., Lau G., Fan S.T., Kung H. and Lin M.C., rAAV-mediated long-term expression of endostatin significantly inhibits the progression of HCC (Abstract), The 4th International Meeting on Hepatocellular Carcinoma: Eastern and Western Experiences, Hong Kong, 14-16 December 2004. |
| Pang R.W.C., Lee K.W., Man K., Poon R.T.P., Fan S.T., Kwong Y.L. and Tse E.W.C., RNAi-mediated silencing of PIN1 inhibits HCC tumorigenicity (Abstract), The 96th Annual Meeting of the American Association for Cancer Research, Anaheim, California, U.S.A., 16-20 April 2005. |
| Pang W.C., Lee K.W., Man K., Poon R.T.P., Fan S.T., Kwong Y.L. and Tse E.W.C., Inhibition of hepatocellular carcinoma tumourigenicity by RNAi-mediated PIN1 silencing (Abstract), The 6th Annual Scientific Meeting, Centre for the Study of Liver Disease, The University of Hong Kong, Hong Kong, 8 January 2005. |
| Pang W.C., Lee K.W., Man K., Poon R.T.P., Fan S.T., Kwong Y.L. and Tse E.W.C., RNAi-mediated PIN1 silencing inhibits HCC trumourigenicity (Abstract), Asian Journal of Surgery. 2005, 28(Suppl 2): S84. |
| Pang W.C., Lee K.W., Man K., Poon R.T.P., Fan S.T., Kwong Y.L. and Tse E.W.C., RNAi-mediated PIN1 silencing inhibits HCC tumourigenicity (Abstract), The 4th International Meeting on Hepatocellular Carcinoma: Eastern and Western Experiences, Hong Kong, 14-16 December 2004. |
| Pang W.C., Lee K.W., Man K., Poon R.T.P., Fan S.T., Kwong Y.L. and Tse E.W.C., RNAi-mediated silencing of PIN1 inhibits HCC tumorigenicity, The 11th Hong Kong International Cancer Congress, Hong Kong, 10-12 November, 2004. |
| Patil M.A., Chua M.S., Pan K.H., Lin R., Lih C.J., Cheung S.T., Ho C., Li R., Fan S.T., Cohen S.N., Chen X. and So S., An integrated data analysis approach to characterize genes highly expressed in hepatocellular carcinoma, Oncogene. 2005, 24(23): 3737-3747. |
| Patil M.A., Zhang J., Ho C., Cheung S.T., Fan S.T. and Chen X., Hedgehog signaling in human hepatocellular carcinoma (Abstract), Proceedings of the American Association for Cancer Research. 2005, 46: 3942. |
| Patil M.A., Zhang J., Ho C., Cheung S.T., Fan S.T. and Chen X., Hedgehog signaling in human hepatocellular carcinoma (Abstract), The 96th Annual Meeting of the American Association for Cancer Research, Anaheim, U.S.A., 16-20 April 2005. |
| Poon R.T.P., Ng K.K.C. and Fan S.T., A phase I/II study of treatment of inoperable hepatocellular carcinoma using transarterial doxorubicin eluting bead embolisation (Invited Lecture), The 6th Annual Scientific Meeting, Centre for the Study of Liver Disease, The University of Hong Kong, Hong Kong, 8 January 2005. 2005. |
| Poon R.T.P. and Fan S.T., Assessment of hepatic reserve for indication of hepatic resection: how I do it, Journal of Hepato-Biliary-Pancreatic Surgery. 2005, 12(1): 31-37. |
| Poon R.T.P., Yang Z., Liu Y., Ho D.W.Y., Lau C.K. and Fan S.T., Blockade of vascular endothelial growth factor (VEGF) receptor enhances the therapeutic efficacy and chemotherapy in hepatocellular carcinoma (Abstract), The 96th Annual Meeting of the American Association for Cancer Research, Anaheim, California, U.S.A., 16-20 April 2005. |
| Poon R.T.P., Fan S.T., Lo C.M., Liu C.L., Lam C.M., Yuen W.K., Yeung C. and Wong J., Improving perioperative outcome expands the role of hepatectomy in management of benign and malignant hepatobiliary diseases: analysis of 1222 consecutive patients from a prospective database, Annals of Surgery. 2004, 240(4): 698-708. |
| Poon R.T.P. and Fan S.T., Is primary resection and salvage transplantation for hepatocellular carcinoma a reasonable strategy? (Letter to the Editor), Annals of Surgery. 2004, 240(5): 925-928. |
| Poon R.T.P., Fan S.T. and Wong J., Liver resection using a saline-linked radiofrequency dissecting sealer for transection of the liver, Journal of the American College of Surgeons. 2005, 200(2): 308-313. |
| Poon R.T.P., Ho J.W.Y., Tong C.S.W., Lau C.P.Y., Ng I.O.L. and Fan S.T., Prognostic significance of serum vascular endothelial growth factor and endostatin in patients with hepatocellular carcinoma, British Journal of Surgery. 2004, 91(10): 1354-1360. |
| Poon R.T.P., Xia F. and Fan S.T., 原發性肝癌的治療原則, In: 芮靜安, 現代癌診斷治療學, 清華大學出版社, 2004, 205-220. |
| Qian Y.B., Liu C.L., Lo C.M. and Fan S.T., Risk factors for biliary complications after liver transplantation, Archives of Surgery. 2004, 139(10): 1101-1105. |
| Sun X., Krissansen G.W., Fung P.C.W., Xu S., Shi J., Man K., Fan S.T. and Xu R., Anti-angiogenic therapy subsequent to adeno-associated-virus-mediated immunotherapy eradicates lymphomas that disseminate to the liver, International Journal of Cancer. 2004, 113(4): 670-677. |
| Tang T.C.M., Poon R.T.P., Guan X.Y. and Fan S.T., Celecoxib suppresses HCC development via the cell cycle arrest pathway (Poster Presentation), The 96th Annual Meeting of the American Association for Cancer Research, Anaheim, California, U.S.A., 16-20 April 2005. |
| Tang T.C.M., Poon R.T.P., Lau C.P.Y., Xie D. and Fan S.T., Cytosolic cyclooxygenase-2 levels correlate with cytosolic vascular endothelial growth factor levels and tumor invasiveness in human hepatocellular carcinoma (Abstract), The 1st Annual Conference for the Organisation for Oncology and Translational Research, Hong Kong, 15-16 October 2004. |
| Tang T.C.M., Poon R.T.P., Guan X.Y. and Fan S.T., The significance of cyclooxygenase-2 in hepatocellular carcinoma (Abstract), The 6th Annual Scientific Meeting, Centre for the Study of Liver Disease, The University of Hong Kong, Hong Kong, 8 January 2005. |
| Tang T.C.M., Poon R.T.P., Lau C.P.Y., Xie D. and Fan S.T., Tumor cyclooxygenase-2 levels correlate with tumor invasiveness in human hepatocellular carcinoma, World Journal of Gastroenterology. 2005, 11(13): 1896-1902. |
| Tian M.G., Tso W.K., Lo C.M., Liu C.L. and Fan S.T., Treatment of hepatic artery thrombosis after orthotopic liver transplantation, Asian Journal of Surgery. 2004, 27(3): 213-217. |
| Wang P.P., Wang J.H., Yan Z.P., Hu M., Lau G., Fan S.T. and Luk J.M.C., Expression of hepatocyte-like phenotypes in bone marrow stromal cells after HGF induction, Biochemical and Biophysical Research Communications. 2004, 320(3): 712-716. |
| Wang X., Luk J.M.C., Leung P.L., Wong W.Y., Stanbridge E.J. and Fan S.T., Alternative mRNA splicing of liver intestine-cadherin in hepatocellular carcinoma, Clinical Cancer Research. 2005, 11(2 Pt 1): 483-489. |
| Wang X., Luk J.M.C., Leung P.L., Ho D.W.Y. and Fan S.T., Overexpressing LI-cadherin genetic polymorphisms (651C/T, IVS6+35A/G) is associated with susceptibility to HCC (Abstract), The 4th International Meeting on Hepatocellular Carcinoma: Eastern and Western Experiences, Hong Kong, 14-16 December 2004. |
| Wang X., Luk J.M.C., Leung P.L., Ho D.W.Y. and Fan S.T., Overexpression LI-cadherin genetic polymorphisms (651C/T, IVS6+35A/G) is associated with susceptibility to HCC (Abstract), Asian Journal of Surgery. 2005, 28(Suppl 2): S107. |
| Wang X., Luk J.M.C., Leung P.L. and Fan S.T., Overexpression of LI-cadherin genetic polymorphisms (651C/T, IVS6+35A/G) is associated with susceptibility to hepatocellular carcinoma (Abstract), The 6th Annual Scientific Meeting, Centre for the Study of Liver Disease, The University of Hong Kong, Hong Kong, 8 January 2005. |
| Wong S.M.Y., Ng K.K.C., Poon R.T.P., Lam C.M., Yuen J., Tso W.K. and Fan S.T., Comparison of radiofrequency ablation and transarterial chemoembolisation for unresectable hepatocellular carcinoma (Abstract), Asian Journal of Surgery. 2005, 28(Suppl 2): S105. |
| Wong S.M.Y., Ng K.K.C., Poon R.T.P., Lam C.M., Yuen J., Tso W.K. and Fan S.T., Comparison of radiofrequency ablation and transarterial chemoembolisation for unresectable hepatocellular carcinoma (Abstract), The 4th International Meeting on Hepatocellular Carcinoma: Eastern and Western Experiences, Hong Kong, 14-16 December 2004. |
| Wu W.H., Wan Y.L., Lee L., Yang Y.M., Huang Y.T., Chen C.L. and Fan S.T., First two cases of living related liver transplantation with complicated anatomy of blood vessels in Beijing, World Journal of Gastroenterology. 2004, 10(19): 2854-2858. |
| Yang Z., Ho D.W.Y., Lam C.T., Luk J.M.C., Lum C.T., Yu W.C., Poon R.T.P. and Fan S.T., Identification of brain-derived neurotrophic factor (BDNF) as a potential therapeutic target in hepatocellular carcinoma (Abstract), The 4th International Meeting on Hepatocellular Carcinoma: Eastern and Western Experiences, Hong Kong, 14-16 December 2004. |
| Yang Z., Ho D.W.Y., Lam C.T., Luk J.M.C., Yu W.C., Lo C.M., Poon R.T.P. and Fan S.T., Identification of brain-derived neurotrophic factor (BDNF) in hepatocellular carcinoma - from animal study to clinical management (Abstract), The 6th Annual Scientific Meeting, Centre for the Study of Liver Disease, The University of Hong Kong, Hong Kong, 8 January 2005. |
| Yang Z., Ho D.W.Y., Lam C.T., Luk J.M.C., Lum C.T., Yu W.C., Poon R.T.P. and Fan S.T., Identification of brain-derived neurotrophic factor as a novel functional protein in hepatocellular carcinoma, Cancer Research. 2005, 65(1): 219-225. |
| Yang Z., Ho D.W.Y., Lam C.T., Luk J.M.C., Poon R.T.P. and Fan S.T., The potential role of allograft inflammatory factor 1 (AIF-1) in macrophage activation in small-for-size liver transplantation, The 20th International Congress of the Transplantation Society, Vienna, Austria, 5-10 September 2004. |
| Yang Z., Poon R.T.P., To J.Y.T., Ho D.W.Y. and Fan S.T., The potential role of hypoxia inducible factor 1a in tumor progression after hypoxia and chemotherapy in hepatocellular carcinoma, Cancer Research. 2004, 64(15): 5496-5503. |
| Yang Z., Poon R.T.P., Luo Y., Cheung C.K.Y., Ho D.W.Y., Lo C.M. and Fan S.T., Up-regulation of vascualr endothelial growth factor (VEGF) in small-for-size liver grafts enhances macrophage activities through VEGF receptor 2-dependent pathway, Journal of Immunology. 2004, 173(4): 2507-2515. |
| Yau T.O., Chan C.Y., Chan K.L., Lee M.F., Wong C.M., Fan S.T. and Ng I.O.L., Frequent down-regulation of HDPR1, a novel inhibitor of WNT/beta-catenin signaling, in hepatocellular carcinoma (Abstract), The 6th Annual Scientific Meeting, Centre for the Study of Liver Disease, The University of Hong Kong, Hong Kong, 8 January 2005. |
| Yau T.O., Chan C.Y., Chan K.L., Lee M.F., Wong C.M., Fan S.T. and Ng I.O.L., HDPR1, a novel inhibitor of WNT/b-catenin signaling, is down-regulated in hepatocellular carcinoma: involvement of promoter hypermethylation, AACR Special Conference in Cancer Research “Chromatin, chromosomes and cancer epigenetics”, Hawaii, USA, November 2004. |
| Yau T.O., Chan C.Y., Chan K.L., Lee M.F., Wong C.M., Fan S.T. and Ng I.O.L., HDPR1, a novel inhibitor of the WNT/beta-catenin signaling, is frequently downregulated in hepatocellular carcinoma: involvement of methylation-mediated gene silencing, Oncogene. 2005, 24(9): 1607-1614. |
| Yau T.O., Chan C.Y., Chan K.L., Lee M.F., Wong C.M., Fan S.T. and Ng I.O.L., Under-expression of HDPR1, a novel inhibitor of WNT/b-catenin signaling pathway, in hepatocellular carcinoma (Abstract), Asian Journal of Surgery. 2005, 28(Suppl 2): S84. |
| Yau T.O., Chan P.C.Y., Chan K.L., Lee M.F., Wong C.M., Fan S.T. and Ng I.O.L., Under-expression of HDPR1, a novel inhibitor of WNT/b-catenin signaling pathway, in hepatocellular carcinoma (Abstract), The 4th International Meeting on Hepatocellular Carcinoma: Eastern and Western Experiences, Hong Kong, 14-16 December 2004. |
| Yong J.L., Lam C.M., Chan O.O., Poon R.T.P., Liu C.L., Lo C.M. and Fan S.T., Better survival in female patients with hepatocellular carcinoma (Abstract), Asian Journal of Surgery. 2005, 28(Suppl 2): S94. |
| Yong J.L., Lam C.M., Chan O.O., Poon R.T.P., Liu C.L., Lo C.M. and Fan S.T., Better survival in female patients with hepatocellular carcinoma (Abstract), The 4th International Meeting on Hepatocellular Carcinoma: Eastern and Western Experiences, Hong Kong, 14-16 December 2004. |
| Yuen M.F., Ng I.O.L., Fan S.T., Yuan H., Wong D.K.H., Yuen J.C.H., Sum S.M., Chan O.O. and Lai C.L., Significance of HBV DNA levels in liver histology of HBeAg and anti-HBe positive patients with chronic hepatitis B, American Journal of Gastroenterology. 2004, 99(10): 2032-2037. |
| Yuen R.M.F., Tanaka K., Mizokami M., Yuen J.C.H., Hui C.K., Wong D.K.H., Yuan H., Sum S.M., Chan O.O., Wong B.C.Y., Fan S.T. and Lai C.L., Role of hepatitis B virus genotypes Ba and C, core promoter and precore mutations on hepatocellular carcinoma: a case control study, Carcinogenesis. 2004, 25(9): 1593-1598. |
| Zhao Y., Man K., Lo C.M., Ng T.P., Li X.L., Sun K.W., Lee K.W., Dai X.W. and Fan S.T., Attenuation of small-for-size liver graft injury by FTY720: significance of cell-survival Akt signaling pathway, American Journal of Transplantation. 2004, 4(9): 1399-1407. |
| Researcher : Fan YW |
| List of Research Outputs |
| Chan T.K.T., Lui W.M. and Fan Y.W., Review of endovascular stent-assisted embolization for management of intracranial aneurysms, 11th Annual Scientific Meeting, The Hong Kong Neurosurgical Society, Hong Kong, 3-4 December 2004. |
| Leung G.K.K., Tsui H.Y., Lee K.K. and Fan Y.W., Experience with post-operative CRH stimulation test in predicting the outcome of surgery for Cushing disease, 11th Annual Scientific Meeting, The Hong Kong Neurosurgical Society, Hong Kong, 3-4 December 2004. |
| Leung G.K.K., Fung P.C., Kwan Y.M., Leung S.H., Li M.W. and Fan Y.W., External ventricular drain with an extended subcutaneous tunnel - its applications and outcome, 11th Annual Scientific Meeting, The Hong Kong Neurosurgical Society, Hong Kong, 3-4 December 2004. |
| Leung G.K.K., Poon S.K., Wong C.K., Chan Y.Y., Tsang W.Y. and Fan Y.W., Protocol-directed ventilator weaning in neurosurgical patients - an on-going pilot study, 11th Annual Scientific Meeting, The Hong Kong Neurosurgical Society, Hong Kong, 3-4 December 2004. |
| Leung G.K.K., Lee W.C., Lui W.M. and Fan Y.W., The APACHE III prognostic system in poor grade subarachnoid haemorrhage, 11th Annual Scientific Meeting, The Hong Kong Neurosurgical Society, Hong Kong, 3-4 December 2004. |
| Leung K.Y., Tang M.H.Y., Lam T.P.W., Fan Y.W., Shek T.W.H., Wong K.Y. and Ngai C.S.W., Prenatal diagnosis of a cavernous angioma associated with intracranial hemorrhag: report of one case and review of the literature, Ultrasound in Obstetrics & Gynecology. John Wiley & Sons, Ltd, 2004, 24(7): 797-804. |
| Lui W.M. and Fan Y.W., Extracranial-intracranial bypass surgery for intracranial aneurysms, 11th Annual Scientific Meeting, The Hong Kong Neurosurgical Society, Hong Kong, 3-4 December 2004. |
| Wong D.Y.H., Leung G.K.K. and Fan Y.W., The significance of incidental culture-positive hardwares in shunt revision procedures, 11th Annual Scientific Meeitng, The Hong Kong Neurosurgical Society, Hong Kong, 3-4 December 2004. |
| Wong S.T., Yung A. and Fan Y.W., Hemispherectomy for epilepsy: Queen Mary Hospital experience, 11th Annual Scientific Meeting, The Hong Kong Neurosurgical Society, Hong Kong, 3-4 December 2004. |
| Yung A.W.Y., Leung C., Sze A., Khong P.L., Ho W.Y., Yuen S.M. and Fan Y.W., Surgical Outcome in 4 Patients Who Had Undergone Epilepsy Surgery, Ruby Jubilee Scientific Meeting, HK, 24-26 Sepember 2004 (Abstract in Hong Kong Journal of Paediatrics (new series). Hong Kong, Medcom Limited, 2004, 9 (suppl): 61. |
| Researcher : Feng X |
| List of Research Outputs |
| Liu Y., Poon R.T.P., Hughes J., Feng X., Yu W.C. and Fan S.T., Chemokine receptors support infiltration of lymphocyte subpopulations in human hepatocellular carcinoma, Clinical Immunology. 2005, 114(2): 174-182. |
| Researcher : Fu M |
| List of Research Outputs |
| Chan K.K., Chen Y.S., Yau T.O., Fu M., Lui V.C.H., Tam P.K.H. and Sham M.H., Hoxb3 vagal neural crest-specific enhancer element for controlling enteric nervous system development, Developmental Dynamics. 2005, 233: 473-483. |
| Fu M., Lui V.C.H., Sham M.H., Pachnis V. and Tam P.K.H., Sonic hedgehog regulates the proliferation, differentiation, and migration of enteric neural crest cells in gut., The Journal of Cell Biology. 2004, 166(5): 673-684. |
| Garcia-Barcelo M.M., Lui V.C.H., Fu M., Li L., Scherer S., Herbrick M.A., Van Heurn E. and Tam P.K.H., New HLBX9 mutations in Currarino patients, XXI Annual International Congress of the British Association of Paediatric Surgeons. Oxford, UK, July 27-30, 2004. |
| Garcia-Barcelo M.M., Ganster R.W., Lui V.C.H., Leon Y.Y., So M.T., Lau A.M.F., Fu M., Sham M.H., Knight J., Zannini M.S., Sham P.C. and Tam P.K.H., TTF-1 and RET promoter SNPs: regulation of RET transcription in Hirschsprung's disease, Human Molecular Genetics. 2005, 14(2): 191-204. |
| Lui V.C.H., Fu M., Sham M.H. and Tam P.K.H., Sonic hedgehog (SHH) promotes proliferation and maintains multi-potency of enteric neural crest stem cells (NCSCs), 51st Annual International Congress of British Association of Paediatric Surgeons, Oxford, U.K. 27-30 July 2004. |
| Lui V.C.H., Fu M., Sham M.H. and Tam P.K.H., Sonic hedgehog (SHH) regulates the migration and differentiation of the enteric neural crest stem cells (NCSCs) in gastrointestinal tract, 51st Annual International Congress of British Association of Paediatric Surgeons, Oxford, U.K. 27-30 July 2004. |
| Researcher : Fu M |
| List of Research Outputs |
| Chan K.K., Chen Y.S., Yau T.O., Fu M., Lui V.C.H., Tam P.K.H. and Sham M.H., Hoxb3 vagal neural crest-specific enhancer element for controlling enteric nervous system development, Developmental Dynamics. 2005, 233: 473-483. |
| Fu M., Lui V.C.H., Sham M.H., Pachnis V. and Tam P.K.H., Sonic hedgehog regulates the proliferation, differentiation, and migration of enteric neural crest cells in gut., The Journal of Cell Biology. 2004, 166(5): 673-684. |
| Garcia-Barcelo M.M., Lui V.C.H., Fu M., Li L., Scherer S., Herbrick M.A., Van Heurn E. and Tam P.K.H., New HLBX9 mutations in Currarino patients, XXI Annual International Congress of the British Association of Paediatric Surgeons. Oxford, UK, July 27-30, 2004. |
| Garcia-Barcelo M.M., Ganster R.W., Lui V.C.H., Leon Y.Y., So M.T., Lau A.M.F., Fu M., Sham M.H., Knight J., Zannini M.S., Sham P.C. and Tam P.K.H., TTF-1 and RET promoter SNPs: regulation of RET transcription in Hirschsprung's disease, Human Molecular Genetics. 2005, 14(2): 191-204. |
| Lui V.C.H., Fu M., Sham M.H. and Tam P.K.H., Sonic hedgehog (SHH) promotes proliferation and maintains multi-potency of enteric neural crest stem cells (NCSCs), 51st Annual International Congress of British Association of Paediatric Surgeons, Oxford, U.K. 27-30 July 2004. |
| Lui V.C.H., Fu M., Sham M.H. and Tam P.K.H., Sonic hedgehog (SHH) regulates the migration and differentiation of the enteric neural crest stem cells (NCSCs) in gastrointestinal tract, 51st Annual International Congress of British Association of Paediatric Surgeons, Oxford, U.K. 27-30 July 2004. |
| Researcher : Ganster RW |
| Project Title: | Regulation of gene transcription by NF-kB and stats downstream of the ret receptor tyrosine kinase in hirschsprung disease and thyroid cancer |
| Investigator(s): | Ganster RW, Tam PKH |
| Department: | Surgery |
| Source(s) of Funding: | Merit Award for RGC CERG Funded Projects |
| Start Date: | 09/2003 |
| Completion Date: | 03/2005 |
| Abstract: |
| To understand the patho-physiological functions of RET receptor tyrosine kinase in Hirschsprung disease (HD) and in thyroid cancers, specifically; Multiple Endocrine Neuroplasia type 2A and 2B (MEN2A/2B), Medullary Thyroid Carcinoma (MTC), and Papillary Thyroid Carcinoma (PTC). |
| Project Title: | Regulation of gene transcription by NF-kB and stats downstream of the ret receptor tyrosine kinase in hirschsprung disease and thyroid cancer |
| Investigator(s): | Ganster RW, Tam PKH |
| Department: | Surgery |
| Source(s) of Funding: | Competitive Earmarked Research Grants (CERG) |
| Start Date: | 09/2003 |
| Completion Date: | 03/2005 |
| Abstract: |
| To understand the patho-physiological functions of RET receptor tyrosine kinase in Hirschsprung disease (HD) and in thyroid cancers, specifically; Multiple Endocrine Neuroplasia type 2A and 2B (MEN2A/2B), Medullary Thyroid Carcinoma (MTC), and Papillary Thyroid Carcinoma (PTC). |
| List of Research Outputs |
| Garcia-Barcelo M.M., Ganster R.W., Lui V.C.H., Leon Y.Y., So M.T., Lau A.M.F., Fu M., Sham M.H., Knight J., Zannini M.S., Sham P.C. and Tam P.K.H., TTF-1 and RET promoter SNPs: regulation of RET transcription in Hirschsprung's disease, Human Molecular Genetics. 2005, 14(2): 191-204. |
| Researcher : Garcia-Barcelo MM |
| Project Title: | Role of RET regulatory polymorphisms in Hirschsprung's disease |
| Investigator(s): | Garcia-Barcelo MM, Tam PKH, Ganster RW |
| Department: | Surgery |
| Source(s) of Funding: | Seed Funding Programme for Basic Research |
| Start Date: | 02/2004 |
| Abstract: |
| To identify and functionally test a RET susceptibility locus which may predispose to disease more than 60% of the Chinese HSCR patients and to replicate our findings in an extended sample. |
| Project Title: | RET regulatory polymorphisms and susceptibility to Hirschsprung's disease |
| Investigator(s): | Garcia-Barcelo MM, Tam PKH, Ganster RW, Sham P.C. |
| Department: | Surgery |
| Source(s) of Funding: | Competitive Earmarked Research Grants (CERG) |
| Start Date: | 09/2004 |
| Abstract: |
| To study the effect of the RET promoter SNPs on transcription, independently and in conjection with other 5' cis-regulatory elements; to identify the transcription factor functioning at the SNPs site; to investigate whether there is functional and/or physical interactions between PHOX2B and the RET promoter; to test our genetic observations on a larger sample of Chinese HSCR patients; to investigate whether there is association between the transmission of HSCR-susceptibility RET haplotypes and PHOX2B-associated polymorphisms in affected individuals. |
| Project Title: | RET regulatory polymorphisms and susceptibility to Hirschsprung's disease |
| Investigator(s): | Garcia-Barcelo MM |
| Department: | Surgery |
| Source(s) of Funding: | Merit Award for RGC CERG Funded Projects |
| Start Date: | 01/2005 |
| Abstract: |
| Refer to hard copy |
| Project Title: | Study of the molecular basis of anorectal malformations |
| Investigator(s): | Garcia-Barcelo MM, Tam PKH, Lui VCH |
| Department: | Surgery |
| Source(s) of Funding: | Seed Funding Programme for Basic Research |
| Start Date: | 01/2005 |
| Abstract: |
| Refer to hard copy |
| List of Research Outputs |
| Garcia-Barcelo M.M., Lui V.C.H., Fu M., Li L., Scherer S., Herbrick M.A., Van Heurn E. and Tam P.K.H., New HLBX9 mutations in Currarino patients, XXI Annual International Congress of the British Association of Paediatric Surgeons. Oxford, UK, July 27-30, 2004. |
| Garcia-Barcelo M.M., Ganster R.W., Lui V.C.H., Leon Y.Y., So M.T., Lau A.M.F., Fu M., Sham M.H., Knight J., Zannini M.S., Sham P.C. and Tam P.K.H., TTF-1 and RET promoter SNPs: regulation of RET transcription in Hirschsprung's disease, Human Molecular Genetics. 2005, 14(2): 191-204. |
| Tam P.K.H. and Garcia-Barcelo M.M., Molecular genetics of Hirschsprung's disease, Seminars in Pediatric Surgery. 2004, 13(4): 236-248. |
| Researcher : He Q |
| Project Title: | Molecular dynamics of iron transport |
| Investigator(s): | He Q |
| Department: | Chemistry |
| Source(s) of Funding: | Competitive Earmarked Research Grants (CERG) |
| Start Date: | 12/2002 |
| Abstract: |
| (1) How the chemical properties of the critical metal-binding ligands affect iron binding and release from transferrin in vitro. (2) How a depleted level of transferrin (and iron) in living cells affects the expression of related proteins in the iron-transport pathway. (3) Study the cellular trafficking of transferrin as a possible pathway for delivering drugs and nano-particles besides iron. |
| Project Title: | Identification of biomarkers for the diagnosis and therapy of Hepatitis B virus (HBV) infection and HBV-induced hepatocellular carcinoma |
| Investigator(s): | He Q, Lau G, Chiu J |
| Department: | Chemistry |
| Source(s) of Funding: | Seed Funding Programme for Applied Research |
| Start Date: | 08/2003 |
| Completion Date: | 09/2004 |
| Abstract: |
| To identify the protein markers associated with HBV inflammation and HBV-related HCC liver cancer by using proteomic technology. |
| Project Title: | Structure-function of the lipoprotein MtsA in MtsABC responsible for iron transport in S. pyogenes bacteria |
| Investigator(s): | He Q |
| Department: | Chemistry |
| Source(s) of Funding: | Seed Funding Programme for Basic Research |
| Start Date: | 03/2004 |
| Completion Date: | 02/2005 |
| Abstract: |
| To study the structure-function of the lipoprotein MtsA and further to characterize the protein's property in the Mts ABC complex as an entire system. |
| Project Title: | Proteomic study of hepatitis B virus (HBV) infection and HBV-related liver necroinflammation |
| Investigator(s): | He Q |
| Department: | Chemistry |
| Source(s) of Funding: | Incentive Award for RGC CERG Fundable But Not Funded Projects |
| Start Date: | 07/2004 |
| Abstract: |
| Refer to hard copy |
| Project Title: | Proteomic profiling of cellular responses to chromium (Cr) cytotoxicity |
| Investigator(s): | He Q |
| Department: | Chemistry |
| Source(s) of Funding: | Seed Funding Programme for Basic Research |
| Start Date: | 04/2005 |
| Abstract: |
| Refer hard copy |
| Researcher : Ho DWY |
| List of Research Outputs |
| Ho D.W.Y., Luk J.M.C. and Fan S.T., Plasma proteomic profiling and identification of circulating biomarkers for monitoring fulminant hepatic failure in a porcine model (Abstract), HUPO 3rd Annual World Congress, Beijing, China, 25-27 October 2004. |
| Ho D.W.Y., Luk J.M.C. and Fan S.T., Plasma proteomic profiling and identification of circulating biomarkers for monitoring fulminant hepatic failure, Molecular and Cellular Proteomics. 2004, 3(10): S112, 8.14. |
| Ho D.W.Y., Yang Z., Lau C.K., To J.Y.T., Luk J.M.C. and Fan S.T., The therapeutic role of cardiotrophin-1 in a rat model with fulminant hepatic failure (Abstract), The 6th Annual Scientific Meeting, Centre for the Study of Liver Disease, The University of Hong Kong, Hong Kong, 8 January 2005. |
| Luk J.M.C., Lam B.K.Y., Lam C.T., Siu F.M., Ho D.W.Y., Yu W.C., Peng J.R., Che C.M., Leng X.S. and Fan S.T., Molecular classification of hepatocellular carcinoma by proteomic expression profiling (Abstract), The 6th Annual Scientific Meeting, Centre for the Study of Liver Disease, The University of Hong Kong, Hong Kong, 8 January 2005. |
| Ng K.K.C., Lam C.M., Poon R.T.P., Shek T.W.H., To J.Y.T., Wo Y.H., Ho D.W.Y. and Fan S.T., Comparison of systemic responses of radiofrequency ablation, cryotherapy, and surgical resection in a porcine liver model, Annals of Surgical Oncology. 2004, 11(7): 650-657. |
| Ng K.K.C., Lam C.M., Poon R.T.P., Shek T.W.H., Ho D.W.Y. and Fan S.T., Maximal host tolerance to large-volume hepatic radiofrequency ablation in a rat model (Abstract), Journal of Gastrointestinal Surgery. 2004, 8( 7 Suppl): 114A. |
| Ng K.K.C., Lam C.M., Poon R.T.P., Shek T.W.H., Ho D.W.Y. and Fan S.T., Maximal host tolerance to large-volume hepatic radiofrequency ablation in a rat model (Abstract), The 19th World Congress of Digestive Surgery, Yokohama, Japan, 8-11 December 2004. |
| Ng K.K.C., Lam C.M., Poon R.T.P., Shek T.W.H., Yu W.C., To J.Y.T., Wo Y.H., Lau C.P.Y., Tang T.C.M., Ho D.W.Y. and Fan S.T., Porcine liver: morphological characteristics and cell viability at experimental radiofrequency ablation with internally cooled electrodes, Radiology. 2005, 235(2): 478-486. |
| Poon R.T.P., Yang Z., Liu Y., Ho D.W.Y., Lau C.K. and Fan S.T., Blockade of vascular endothelial growth factor (VEGF) receptor enhances the therapeutic efficacy and chemotherapy in hepatocellular carcinoma (Abstract), The 96th Annual Meeting of the American Association for Cancer Research, Anaheim, California, U.S.A., 16-20 April 2005. |
| Wang X., Luk J.M.C., Leung P.L., Ho D.W.Y. and Fan S.T., Overexpressing LI-cadherin genetic polymorphisms (651C/T, IVS6+35A/G) is associated with susceptibility to HCC (Abstract), The 4th International Meeting on Hepatocellular Carcinoma: Eastern and Western Experiences, Hong Kong, 14-16 December 2004. |
| Wang X., Luk J.M.C., Leung P.L., Ho D.W.Y. and Fan S.T., Overexpression LI-cadherin genetic polymorphisms (651C/T, IVS6+35A/G) is associated with susceptibility to HCC (Abstract), Asian Journal of Surgery. 2005, 28(Suppl 2): S107. |
| Yang Z., Ho D.W.Y., Lam C.T., Luk J.M.C., Lum C.T., Yu W.C., Poon R.T.P. and Fan S.T., Identification of brain-derived neurotrophic factor (BDNF) as a potential therapeutic target in hepatocellular carcinoma (Abstract), The 4th International Meeting on Hepatocellular Carcinoma: Eastern and Western Experiences, Hong Kong, 14-16 December 2004. |
| Yang Z., Ho D.W.Y., Lam C.T., Luk J.M.C., Yu W.C., Lo C.M., Poon R.T.P. and Fan S.T., Identification of brain-derived neurotrophic factor (BDNF) in hepatocellular carcinoma - from animal study to clinical management (Abstract), The 6th Annual Scientific Meeting, Centre for the Study of Liver Disease, The University of Hong Kong, Hong Kong, 8 January 2005. |
| Yang Z., Ho D.W.Y., Lam C.T., Luk J.M.C., Lum C.T., Yu W.C., Poon R.T.P. and Fan S.T., Identification of brain-derived neurotrophic factor as a novel functional protein in hepatocellular carcinoma, Cancer Research. 2005, 65(1): 219-225. |
| Yang Z., Ho D.W.Y., Lam C.T., Luk J.M.C., Poon R.T.P. and Fan S.T., The potential role of allograft inflammatory factor 1 (AIF-1) in macrophage activation in small-for-size liver transplantation, The 20th International Congress of the Transplantation Society, Vienna, Austria, 5-10 September 2004. |
| Yang Z., Poon R.T.P., To J.Y.T., Ho D.W.Y. and Fan S.T., The potential role of hypoxia inducible factor 1a in tumor progression after hypoxia and chemotherapy in hepatocellular carcinoma, Cancer Research. 2004, 64(15): 5496-5503. |
| Yang Z., Poon R.T.P., Luo Y., Cheung C.K.Y., Ho D.W.Y., Lo C.M. and Fan S.T., Up-regulation of vascualr endothelial growth factor (VEGF) in small-for-size liver grafts enhances macrophage activities through VEGF receptor 2-dependent pathway, Journal of Immunology. 2004, 173(4): 2507-2515. |
| Researcher : Ho JCY |
| List of Research Outputs |
| Cheung S.T., Ho J.C.Y., Leung K.L., Chen X., Fong D.Y.T., So S. and Fan S.T., Transcript AA454543 is a novel prognostic marker for hepatocellular carcinoma after curative partial hepatectomy, Neoplasia. 2005, 7(2): 91-98. |
| Ho J.C.Y., Cheung S.T., Leung K.L., Ng I.O.L. and Fan S.T., Decreased expression of cytochrome P450 2E1 is associated with poor prognosis of hepatocellular carcinoma, International Journal of Cancer. 2004, 111(4): 494-500. |
| Ho J.C.Y., Cheung S.T. and Fan S.T., Up-regulation of glycosylphatidylinositols anchor attachment protein (GAA1), a novel oncogene, in hepatocellular carcinoma (Abstract), Asian Journal of Surgery. 2005, 28(Suppl 2): S89. |
| Ho J.C.Y., Cheung S.T. and Fan S.T., Up-regulation of glycosylphatidylinositols anchor attachment protein (GAA1), a novel oncogene, in hepatocellular carcinoma (Abstract), The 4th International Meeting on Hepatocellular Carcinoma: Eastern and Western Experiences, Hong Kong, 14-16 December 2004. |
| Ho J.C.Y., Cheung S.T. and Fan S.T., Up-regulation of glycosylphatidylinositols anchor attachment protein 1 (GAA1), a novel oncogene, in hepatocellular carcinoma (Abstract), The 6th Annual Scientific Meeting, Centre for the Study of Liver Disease, The University of Hong Kong, Hong Kong, 8 January 2005. |
| Researcher : Ho JWC |
| Project Title: | The Hereditary Gastrointestinal Cancer Registry - a programme for the people of Hong Kong |
| Investigator(s): | Ho JWC, Yuen ST, Chung LP, Kwan KYM |
| Department: | Surgery |
| Source(s) of Funding: | Terry Fox Fellowship |
| Start Date: | 06/2000 |
| Abstract: |
| To achieve colorectal cancer prevention in high risk families through early detection and timely treatment; to raise awareness of hereditary colorectal cancer through education of the public and the health care profession so as to ensure proper referral of these families to our Registry for the delivery of proper preventive service; to establish support services to improve psychosocial well beings of affected individuals and their at-risk family members; to improve the understanding of hereditary colorectal cancer and its management. |
| List of Research Outputs |
| Cheung T.T., Law W.L., Ho J.W.C., Lee Y.M., Seto C.L. and Choi H.K., Outcome of synchronous cystectomy in patients with advanced primary colorectal cancer, 19th World Congress of ISDS, Yokohama, Japan, 8-11 December 2004. |
| Cheung T.T., Law W.L., Ho J.W.C., Lee Y.M., Seto C.L. and Choi H.K., Outcome of synchronous cystectomy in patients with advanced primary colorectal cancer, Journal of Gastrointestinal Surgery. 2004, 8, No. 7S: 191A-P60. |
| Chim J.C.S., Ho J.W.C., Ooi C.G.C., Choy C. and Liang R.H.S., Primary anaplastic large cell lymphoma of the pancreas, Leukaemia & Lymphoma. 2005, 46(3): 457-9. |
| Choi H.K., Law W.L., Ho J.W.C. and Chu K.W., Value of gastrografin in adhesive small bowel obstruction after unsuccessful conservative treatment: a prospective evaluation, World Journal of Gastroenterology. 2005, 11 (24): 3742-3745. |
| Ho J.W.C., Colorectal cancer - environmental and hereditary factors, Hong Kong Anti-Cancer Society: Cancer Talk, Hong Kong, 28 August 2004. |
| Ho J.W.C., Colorectal cancer and lifestyle, Manulife Health Talk, Hong Kong, 13 November 2004. |
| Ho J.W.C., Colorectal cancer: prevention and screening. Symposium for medical & health professionals: colorectal cancer - prevention & care in 21 Century, Hong Kong Anti-Cancer Society, Hong Kong, 17 April 2005. |
| Ho J.W.C., Early-onset colorectal cancer in Hong Kong Chinese: epidemiology, genetic and clinical studies, Research Meeting, Centre for Academic Surgery, Royal London Hospital, London, UK, 20 September 2004. |
| Ho J.W.C., Epidemiology and screening of colorecal cancer, "Care for the Ostomates: Transdisciplinary Collaboration" Symposium, 25th Anniversary of the Hong Kong Stoma Association, Hong Kong, 20 November 2004. |
| Ho J.W.C., Explaining genetic cancer risk: a cultural crash course. Eastern promise, First Conference of InSiGHT, Newcastle upon Tyne, UK, 14-17 June 2005. |
| Ho J.W.C., Impact of Hereditary GI Cancer Registry, International Colorectal Disease Symposium, Hong Kong, February 2005. |
| Ho J.W.C., Ho M.Y., Wong K., Chan C.L.W., Chan E. and Yuen S.T., Psychological profile of colorectal cancer genetic testing recipitnes in Hong Kong, Familial Cancer. 2005, 4 (Supp 1): 50 (F33). |
| Ho J.W.C., Ho M.Y., Wong K., Chan C.L.W., Chan E. and Yuen S.T., Psychological profile of colorectal cancer genetic testing recipitnes in Hong Kong, First Conference of InSiGHT, Newcastle upon Tyne, UK, 14-17 June 2005. |
| Ho J.W.C., Screening for colon cancer, are we ready in Hong Kong?, Alimentary Disease Weekend, The University of Hong Kong, Hong Kong, 18-19 September 2004. |
| Law W.L., Ho J.W.C., Chan T.T., Au G.K.H. and Chu K.W., Outcome of anterior resection for stage II rectal cancer without radiation: the role of adjuvant chemotherapy, Diseases of the Colon & Rectum. 2005, 48(2): 218-226. |
| Law W.L., Ng K.C., Lee Y.M., Ho J.W.C., Choi H.K. and Seto C.L., Self-expanding metallic stent as a bridge to surgery versus emergency operation for obstructing left sided colorectal cancer: a case-matched study, Digestive Disease Week, Chicago, USA, 16-19 May 2005. |
| Law W.L., Ng K.C., Ng K.C., Lee Y.M., Ho J.W.C., Choi H.K. and Seto C.L., Self-expanding metallic stent as a bridge to surgery versus emergency operation for obstructing left sided colorectal cancer: a case-matched study, Gastroenterology. 2005, 128 (4): A799, Suppl. 2. |
| Lee A.M., Tang V.Y.H., Chan C.L.W., Leung P.P.Y. and Ho J.W.C., Younger patients with colorectal cancer are more distressed: the role of body image and negative support, 11th Hong Kong International Cancer Congress, Hong Kong, November 2004. |
| Pun T.C. and Ho J.W.C., Case Reports - LAVH after low anterior resection, Gynecology Surgery. Springer-Verlag Berlin, 2004, 1: 207-208. |
| Tang V.Y.H., Lee A.M., Chan C.L.W., Leung P.P.Y. and Ho J.W.C., Disorientation and Reconstruction: Dynamic Adaptation of Patients with Colorectal Cancer, 11th Hong Kong International Cancer Congress. Hong Kong, 2004. |
| Researcher : Ho JWY |
| List of Research Outputs |
| Chua C.W., Lee T.W., Ling M.T., Man K., Ho J.W.Y., Ho J.W.Y., Ho J.W.Y., Ho J.W.Y., Ho J.W.Y., Wang X. and Wong Y.C., FTY720, a fungus metabolite, inhibits in vivo growth of androgen-independent prostate cancer, International Journal of Cancer. 2005, Equib ahead of print. |
| Ho J.W.Y., Poon R.T.P., Tong C.S.W. and Fan S.T., Clinical significance of serum vascular cell adhesion molecule-1 levels in patients with hepatocellular carcinoma, World Journal of Gastroenterology. 2004, 10(14): 2014-2018. |
| Ho J.W.Y., Poon R.T.P., Sun K.W., Xue W.C. and Fan S.T., Clinicopathological and prognostic implications of endoglin (CD105) expression in hepatocellular carcinoma and its adjacent non-tumorous liver, World Journal of Gastroenterology. 2005, 11(2): 176-181. |
| Ho J.W.Y., Man K., Sun K.W., Poon R.T.P. and Fan S.T., Effective low dose combined-drug treatment using FTY720 and Gleeve in hepatocellular carcinoma (Abstract), The 6th Annual Scientific Meeting, Centre for the Study of Liver Disease, The University of Hong Kong, Hong Kong, 8 January 2005. |
| Ho J.W.Y., Man K., Sun K.W., Poon R.T.P. and Fan S.T., Effective low dose combined-drug treatment using FTY720 and Gleevec in hepatocellular carcinoma (Abstract), Asian Journal of Surgery. 2005, 28(Suppl 2): S82. |
| Ho J.W.Y., Man K., Sun K.W., Poon R.T.P. and Fan S.T., Effective low dose combined-drug treatment using FTY720 and Gleevec in hepatocellular carcinoma (Abstract), The 4th International Meeting on Hepatocellular Carcinoma: Eastern and Western Experiences, Hong Kong, 14-16 December 2004. |
| Lee K.W., Man K., Ho J.W.Y., Sun K.W., Ng T.P., Wang X., Wong Y.C., Ng I.O.L., Xu R. and Fan S.T., FTY720 induces apoptosis of human hepatoma cell lines through PI3-K-mediated Akt dephosphorylation, Carcinogenesis. 2004, 25(12): 2397-2405. |
| Lee K.W., Man K., Ho J.W.Y., Wang X., Poon R.T.P., Sun K.W., Ng T.P., Ng I.O.L., Xu R. and Fan S.T., Significance of the Rac signaling pathway in HCC cell motility: implications for a new therapeutic target, Carcinogenesis. 2005, 26(3): 681-687. |
| Man K., Ng T.P., Lee K.W., Lo C.M., Sun K.W., Li X., Zhao Y., Ho J.W.Y. and Fan S.T., FTY720 attenuates hepatic ischemia-reperfusion injury in normal and cirrhotic livers, American Journal of Transplantation. 2005, 5(1): 40-49. |
| Man K., Ng T.P., Lo C.M., Sun K.W., Zhao Y., Ho J.W.Y., Lee K.W. and Fan S.T., Hepatic I/R injury on small liver remnant promotes liver tumor growth and metastasis - activation of cell invasion and migration pathways (Abstract), The 20th International Congress of the Transplantation Society, Vienna, Austria, 5-10 September 2004. |
| Poon R.T.P., Ho J.W.Y., Tong C.S.W., Lau C.P.Y., Ng I.O.L. and Fan S.T., Prognostic significance of serum vascular endothelial growth factor and endostatin in patients with hepatocellular carcinoma, British Journal of Surgery. 2004, 91(10): 1354-1360. |
| Researcher : Ho KMT |
| List of Research Outputs |
| Ho K.M.T., Li A.Z., Yiu M.K., Lee K.C., Lui V.C.H., Fung P.C.W., Yiu T.F. and Tam P.K.H., Altered expression of aquaporin-2 in human explants with chronic renal allograft dysfunction, BJU International. 2005, 95: 1104-1108. |
| Researcher : Ho WK |
| Project Title: | Effect of chemotherapy on cochlear function |
| Investigator(s): | Ho WK |
| Department: | Surgery |
| Source(s) of Funding: | Other Funding Scheme |
| Start Date: | 06/1996 |
| Abstract: |
| To assess the severity of cochlear damage in patient receiving chemotherapy for cancer. |
| Project Title: | Evaluation of a novel electronic device in screening for obstructive sleep syndrome in snore |
| Investigator(s): | Ho WK, Chung KF |
| Department: | Surgery |
| Source(s) of Funding: | Other Funding Scheme |
| Start Date: | 03/2002 |
| Abstract: |
| To evaluate the accuracy of the SleepStrip as a tool for obstructive sleep apnea screening insnorers. |
| Project Title: | Middle ear effusion in nasopharyngeal carcinoma: conservative versus aggressive treatment; and fluid analysis for underlying mechanism |
| Investigator(s): | Ho WK, Au DKK |
| Department: | Surgery |
| Source(s) of Funding: | Incentive Award for RGC CERG Fundable But Not Funded Projects |
| Start Date: | 07/2003 |
| Abstract: |
| To test the hypothesis of conservative management of middle ear effusion in NPC is as good as aggressive management with myringotomy and grommet insertion in terms of hearing outcome; to investigate the hypothesis of tumor involvement, inflammatory response, infection play significant roles in underlying mechanism in OME in NPC. |
| Project Title: | Study of changes in upper airway pressure in patients before and after upper airway surgery for sleep-related breathing disorders: identification of levels of collapse and prediction of surgical response |
| Investigator(s): | Ho WK, Wei WI |
| Department: | Surgery |
| Source(s) of Funding: | Small Project Funding |
| Start Date: | 11/2003 |
| Abstract: |
| To evaluate the using of multi-level pressure measurements to correlate with the result of surgical treatment. |
| List of Research Outputs |
| Ho W.K., A cure for snoring ?, Medical Tribune, Hong Kong Focus. 2004. |
| Ho W.K., An innovation to treat disturbing snoring: the soft palate implant, Scientific Meeting. The Hong Kong College of Otorhinolaryngologists. Hong Kong, 2004. |
| Ho W.K., Double-blind randomized controlled trial comparing merocel with rapid rhino nasal packs after routine nasal surgery (Letter to the Editor), Rhinology. 2004, 42(4): 255. |
| Ho W.K., Ng W.M. and Wei W.I., Laryngectomy for thyroid cancer involving the upper aerodigestive tract. , 6th International Conference on Head and Neck Cancer. . Washington, USA, 2004. |
| Ho W.K., Ng W.M., Wei W.I. and Yuen P.W., Ortner’s Syndrome: A radiological diagnosis. Poster presentation, 12th Annual Scientific Meeting, Hong Kong College of Radiologists. . Hong Kong, 2004. |
| Ho W.K., Sleep-related breathing disorders_Snoring and Sleep Apnea. , CME lecture for Watson’s Pharmacists.. Hong Kong, 2005. |
| Ho W.K., Snoring and Obstructive Sleep Apnea Syndrome. , TV Program. City Leisure, Channel Jade, Television Broadcasting Ltd.. Hong Kong, 2004. |
| Ho W.K., Snoring and Obstructive Sleep Apnea Syndrome. , Radio Program. RadioTelevision Hong Kong. Channel 1.Smart at 1 o-clock. Hong Kong, 2005. |
| Ho W.K., Surgical Salvage for recurrent nasopharyngeal carcinoma. Mini- symposium. , 5th European Congress of Oto-rhino-laryngology Head and Neck Surgery. Rodos, Greece, 2004. |
| Ho W.K., The new surgery for snoring developed by the University of Hong Kong, Radio Program. RadioTelevision Hong Kong. Channel 1.Smart at 1 o'clock. . Hong Kong, 2004. |
| Hui Y., Wong S.Y., Ho W.K. and Wei W.I., (2) OT 43 A prospective controlled double-blind trial of great auricular nerve preservation at parotidectomy. Am J Surg. 2003 Jun;185(6):574-9, In: Paparella MM, Otto RA, Keefe MA, Year Book of Otolaryngology-Head and Neck Surgery 2004. Mosby, 2004, (2) OT 43. |
| Ng W.M., Koh A.J.H. and Ho W.K., Endoscopic sural nerve harvesting for facial nerve reconstruction How I do it. A targeted problem and its solution., Laryngoscope. 2005, 115: 925. |
| Wei W.I. and Ho W.K., Management of the N0 neck-reference or preference (Epub ahead of print), Oral Oncology. Epub ahead of print, 2005, internet publication. |
| Wei W.I. and Ho W.K., Palatal implant for snoring, Media Interview . Faculty of Medicine, the University of Hong Kongand Health columns in major Hong Kong newspapers and TV channels. Hong Kong, 2004. |
| Wei W.I., Yuen P.W., Ng W.M., Ho W.K., Kwong D.L.W. and Sham J.S.T., Quantitative analysis of plasma cell-free epstein-barr virus DNA in nasopharyngeal carcinoma after salvage nasopharyngectomy: a prospective study, Head & Neck. 2004, 26: 878-883. |
| Wei W.I. and Ho W.K., Surgery for snoring, Medical Progress. 2004, 31: 538-542. |
| Researcher : Ho WY |
| List of Research Outputs |
| Ho W.Y., Selective plasma filtration as the liver support system for patients with fulminant hepatic failure, Thesis, Master of Philosophy, The University of Hong Kong,. 2004. |
| Researcher : Hu M |
| List of Research Outputs |
| Wang P.P., Wang J.H., Yan Z.P., Hu M., Lau G., Fan S.T. and Luk J.M.C., Expression of hepatocyte-like phenotypes in bone marrow stromal cells after HGF induction, Biochemical and Biophysical Research Communications. 2004, 320(3): 712-716. |
| Researcher : Huang X |
| List of Research Outputs |
| Ren Y., Lin C.L., Li Z., Chen X.Y., Huang X., Lui V.C.H., Nicholls J.M., Lan H.Y. and Tam P.K.H., Up-regulation of macrophage migration inhibitory factor in infants with acute neonatal necrotizing enterocolitis, Histopathology. 2005, 46(6): 659-667. |
| Researcher : Hui Y |
| List of Research Outputs |
| Au D.K.K., Hui Y., Chow C.K. and Wei W.I., 香港失聰幼兒早期人工耳蝸植入後的聽力和言語康復, Chinese Scientific Journal of Hearing and Speech Rehabilitation. 2004, 6: 14-16. |
| Au D.K.K., Chu K.M.Y., Chow C.K., Hui Y. and Wei W.I., Cognitive abilities of patients with cochlear implant in the discrimination of tone stimuli with minimal contrast, Cochlear Implant International, The Proceedings of the Fourth Asian-Pacific Symposium on Cochlear Implant and Related Sciences, Taipei, Taiwan, 2003. 2004, 5 (Suppl. 1): 179-181. |
| Au D.K.K., Hui Y. and Chow C.K., Implantable bone-anchored hearing aids to solve hearing problems, Hong Kong East & Hong Kong West Clusters Joint Rehabilitation Scientific Conference, 30 October 2004. |
| Chan Y.E.T., Ng D.K.K., Chong A.S.F., Hui Y. and Fu Y.M., Congenital nasal pyriform aperture stenosis with semilobar holoprosencephaly, International Journal of Pediatric Otorhinolaryngology. 2005, 69: 93-96. |
| Chow C.K., Hui Y. and Au D.K.K., A rare cause of sudden hearing loss in Chinese: cochlear involvement of sarcoidosis, The Internet Journal of Otohinolaryngology. 2004, 3 (1): On-line. |
| Chow C.K., Hui Y., Au D.K.K. and Chu K.M.Y., Minimally invasive surgery for different types of cochlear implant, Cochlear Implants International, The Proceedings of the Fourth Asian-Pacific Symposium on Cochlear Implant and Related Sciences, Taipei, Taiwan, 2003. 2004, 5 (Suppl 1): 75-77. |
| Chu K.M.Y., Au D.K.K., Hui Y., Chow C.K. and Wei W.I., Short electrode insertion in cochlear implantation: Speech perception performance of Cantonese-speaking subjects, Acta Oto-Laryngologica. 2005, 125: 718-724. |
| Chu K.M.Y., Au D.K.K., Hui Y., Chow C.K., Wong R.K. and Wei W.I., Short electrode insertion on cochlear implants: performance on speech perception, Cochlear Implant International, The Proceedings of the Fourth Asian-Pacific Symposium on Cochlear Implant and Related Sciences, Taipei, Taiwan, 2003. 2004, 5 (Suppl 1): 126-128. |
| Hui Y., Wong S.Y., Ho W.K. and Wei W.I., (2) OT 43 A prospective controlled double-blind trial of great auricular nerve preservation at parotidectomy. Am J Surg. 2003 Jun;185(6):574-9, In: Paparella MM, Otto RA, Keefe MA, Year Book of Otolaryngology-Head and Neck Surgery 2004. Mosby, 2004, (2) OT 43. |
| Hui Y., Bone Anchored Hearing Aid, To members of HK operating theatre & Sterile Supply Nurses Association May 9, 2005, HAHO. 2005. |
| Hui Y., Bone anchored hearing aid, Deaf school teachers, Hong Kong Society for the Deaf, 26 August 2004. 2004. |
| Hui Y., Common Pediatric ENT problems and management, Government family physicians of Macau, Macau, 3 July 2004. 2004. |
| Hui Y., Management of allergic rhinitis and sinusitis in children - the surgeon's perspective, Postgraduate Diploma in Child and Adolescent Medicine Organized by the Department of Pediatrics and Adolescent Medicine, University of Hong Kong, May 5, 2005, Queen Mary Hospital. 2005. |
| Hui Y., Member of Editorial Board (March 2001 - present), 中國耳鼻喉顱底外科雜誌, 2005. |
| Hui Y., Member of Editorial Board (September 2003 - present), 中國聽力語言康復科學雜誌, 2005. |
| Hui Y., Shanghai International Pediatric Forum, June 16-18 2005. |
| Hui Y., Technique of Rigid Endoscopy, International Pediatric Respiratory, Allergy and Immunology Congress 2004 (IPRAC) July 10-13, 2004 Hong Kong. 2004. |
| Hui Y., Technique of rigid endoscopy, Pre-congress Course on "Pediatric Bronchoscopy", International Pediatric Respiratory, Allergy and Immunology Congress 2004, Hong Kong, 10-13 July 2004 . 2004. |
| Hui Y., surgical Management of Drooloing, Hong Kong Society of Child Neurology and Developmental Pediatrics Annual Scientific Meeting, November 20 2004. Queen Elizabeth Hospial. 2004. |
| Hui Y., 喉嚨發炎, 精靈一點點, 健康一點點, Feb 8 2005. 2005. |
| Hui Y., 常見小兒阻塞性上呼吸道疾病之冶療, 小兒流涎之手術冶療, National Pediatric ENT conference, October 24-26, 2004, Xiamen China. 2004. |
| Hui Y., 電子耳蝸手術併發症之預防及治療, 中華醫學會遼寧省耳鼻咽喉分會第十九次學術會議, May 20-21 2005 Shenyang. 2005. |
| Lee S.L. and Hui Y., Outcome of severe congenital laryngomalacia (Poster Presentation), International Pediatric Respiratory, Allergy and Immunology Congress, Hong Kong, 10-13 July 2004. 2004. |
| Poon D.M.Y., Chow C.K., Au D.K.K., Hui Y. and Leung M.C.P., Translation of the dizziness handicap inventory into Chinese, validation of it, and evaluation of the quality of life of patients with chronic dizziness, The Annals of Otology, Rhinology & Laryngology. 2004, 113: 12. |
| Wong Y.K., Hui Y., Au D.K.K., Jin H. and Wei W.I., 人工耳蝸植入術的經濟學價值, Chinese Journal of Otorhinolaryngology. 2004, 39(12): 755-756. |
| Researcher : Ip YC |
| List of Research Outputs |
| Cheung S.T., Leung K.L., Ip Y.C., Chen X., Fong D.Y.T., Ng I.O.L., Fan S.T. and So S., Claudin-10 expression level is associated with recurrence of primary hepatocellular carcinoma, Clinical Cancer Research. 2005, 11(2 Pt 1): 551-556. |
| Ip Y.C., MT1-MMP in relation to metastasis of hepatocellular carcinoma , Thesis, Doctor of Philosophy, The University of Hong Kong. 2005. |
| Researcher : Jiang G |
| List of Research Outputs |
| Ren Y., Chen Y., Li W., Jiang G., Liu Q., Chan H.M. and Tam P.K.H., Anti-sense gene therapy for human neuroblastoma by targeting disruption of macrophage migration inhibitory factor (MIF): in vitro and nude mice studies, 51st Annual International Congress of British Association of Paediatric Surgeons, Oxford, U.K. 27-30 July 2004. |
| Researcher : Jin H |
| List of Research Outputs |
| Jin H., Perioperative strategies to improve the benefit of cochlear implantation in a Cantonese speaking population, Thesis, Master of Philosophy, The University of Hong Kong. 2004. |
| Wong Y.K., Hui Y., Au D.K.K., Jin H. and Wei W.I., 人工耳蝸植入術的經濟學價值, Chinese Journal of Otorhinolaryngology. 2004, 39(12): 755-756. |
| Researcher : Jin H |
| List of Research Outputs |
| Jin H., Perioperative strategies to improve the benefit of cochlear implantation in a Cantonese speaking population, Thesis, Master of Philosophy, The University of Hong Kong. 2004. |
| Wong Y.K., Hui Y., Au D.K.K., Jin H. and Wei W.I., 人工耳蝸植入術的經濟學價值, Chinese Journal of Otorhinolaryngology. 2004, 39(12): 755-756. |
| Researcher : Ko S |
| List of Research Outputs |
| Ko S., Luk J.M.C., Wong W.Y., Leung S.Y. and Chu K.M., CDX2 co-localizes with liver-intestine cadherin in intestinal metaplasia and adenocarcinoma of stomach, 6th International Gastric Cancer of Congress, Yokohama, Japan, 4-7 May 2005. |
| Ko S., Chu K.M., Luk J.M.C., Wong W.Y., Yuen S.T., Leung S.Y. and Wong J., CDX2 co-localizes with liver-intestine cadherin in intestinal metaplasia and adenocarcinoma of stomach, Journal of Pathology . 2005, 205: 615-622. |
| Researcher : Koh AJH |
| List of Research Outputs |
| Ng W.M., Koh A.J.H. and Ho W.K., Endoscopic sural nerve harvesting for facial nerve reconstruction How I do it. A targeted problem and its solution., Laryngoscope. 2005, 115: 925. |
| Researcher : Kok TW |
| List of Research Outputs |
| Liu Y., Poon R.T.P., Li Q., Kok T.W., Lau C.P.Y. and Fan S.T., Both antiangiogenesis- and angiogenesis-independent effects are responsible for hepatocellular carcinoma growth arrest by tyrosine kinase inhibitor PTK787/ZK222584, Cancer Research. 2005, 65(9): 3691-3699. |
| Researcher : Kwok HH |
| List of Research Outputs |
| Cheung S.T., Leung K.L., Kwok H.H., Wong S.Y. and Fan S.T., DNALI1 expression and gene polymorphism are associated with disease recurrence after curative surgery in hepatocellular carcinoma (Abstract), The 96th Annual Meeting of the American Association for Cancer Research, Anaheim, California, U.S.A., 16-20 April 2005. |
| Researcher : Lam BKY |
| List of Research Outputs |
| Luk J.M.C., Lam B.K.Y., Yi X., Peng J., Leng X. and Fan S.T., Applicability of proteomic biomarkers set to distinguish hepatocellular carcinoma from non-tumor and healthy liver tissues, Molecular and cellular proteomics. 2005, 4(8) suppl. 13.55: S119. |
| Luk J.M.C., Lam B.K.Y., Lam C.T., Siu F.M., Ho D.W.Y., Yu W.C., Peng J.R., Che C.M., Leng X.S. and Fan S.T., Molecular classification of hepatocellular carcinoma by proteomic expression profiling (Abstract), The 6th Annual Scientific Meeting, Centre for the Study of Liver Disease, The University of Hong Kong, Hong Kong, 8 January 2005. |
| Luk J.M.C., Cheung N., Lam B.K.Y. and Fan S.T., Proteomic roadmap of mouse liver development from embryo to adult, The 4th HUPO Annual Congress, Munich, Germany, 28 August - 1 September 2005. |
| Researcher : Lam BYH |
| List of Research Outputs |
| Luk J.M.C., Lam B.Y.H., Yi X., Peng J., Leng X. and Fan S.T., Applicability of proteomic biomarkers set to distinguish hepatocellular carcinoma from non-tumor and healthy liver tissues, 4th HUPO Annual Congress, Munich, Germany, 28 August - 1 September 2005. |
| Luk J.M.C., Cheung N., Lam B.Y.H. and Fan S.T., Proteomic roadmap of mouse liver development from embryo to adult, Molecular and cellular proteomics. 2005, 4(8) Suppl 8.3: S77. |
| Researcher : Lam CM |
| List of Research Outputs |
| Chan S.Y., Poon R.T.P., Ng K.K.C., Lam C.M. and Fan S.T., Management of carcinoma of gallbladder: a single-institution expereince in 16 years (Abstract), Journal of Gastrointestinal Surgery. 2004, 8(7 Suppl): 68A. |
| Chan S.Y., Poon R.T.P., Ng K.K.C., Lam C.M. and Fan S.T., Management of carcinoma of gallbladder: a single-institution expereince in 16 years (Abstract), The 19th World Congress of Digestive Surgery, Yokohama, Japan, 8-11 December 2004. |
| Chok K.S.H., Lam C.M., Li F.K., Ng K.K.C., Poon R.T.P., Lo C.M. and Fan S.T., Management of hepatocellular carcinoma in renal transplant recipients, Journal of Surgical Oncology. 2004, 87(3): 139-142. |
| Chok K.S.H., Ng K.C.K., Lam C.M., Ng K.K.C., Poon R.T.P. and Fan S.T., Selection portal vein clamping for radiofrequency ablation of hepatocellular carcinoma with portal vein invasion, Journal of Gastrointestinal Surgery. 2005, 9(4): 489-493. |
| Lai A.T.Y., Lam C.M., Ng K.K.C., Yeung C., Ho W.L., Poon L.T. and Ng I.O.L., Hepatic actinomycosis presenting as a liver tumour: Case report and literature review, Asian Journal of Surgery. 2004, 27(4): 345-347. |
| Lam C.M., Yuen A.W., Wai A.C., Leung R.M., Lee A.Y., Ng K.K.C. and Fan S.T., Gallbladder cancer presenting with acute cholecystitis: a population-based study, Surgical Endoscopy. 2005, 19(5): 697-701. |
| Lam C.M., Fan S.T., Yuen A. and Wai A., Institutional volume determines the outcome of non-pancreatic periampullary lesions after pancreaticoduodenectomy (Abstract), HPB. 2005, 7(1 Suppl): 111. |
| Lam C.M., Institutional volume determines the outcome of non-pancreatic periampullary lesions after pancreaticoduodenectomy (Invited Lecture), The 6th Congress of the European Hepato-Pancreato-Biliary Association, Heidelberg, Germany, 25-28 May 2005. |
| Lam C.M., Ng K.K.C., Poon R.T.P., Yuen H.F. and Fan S.T., Thoracoscopic RFA (Abstract), Asian Journal of Surgery. 2005, 28(Suppl 2): S77. |
| Lam C.M., Ng K.K.C., Poon R.T.P., Yuen H.F. and Fan S.T., Thoracoscopic RFA (Invited Lecture), The 4th International Meeting on Hepatocellular Carcinoma: Eastern and Western Experiences, Hong Kong, 14-16 December 2004. |
| Ng K., Lam C.M., Liu C.L. and Fan S.T., Surgical treatment of colorectal liver metastases (Abstract), The 6th Annual Scientific Meeting, Centre for the Study of Liver Disease, The University of Hong Kong, Hong Kong, 8 January 2005. |
| Ng K.K.C., Poon R.T.P., Lam C.M., Yuen J., Tso W.K. and Fan S.T., Comparison of radiofrequency ablation and transarterial chemoembolization for unresectable hepatocellular carcinoma (Abstract), Journal of Gastrointestinal Surgery. 2004, 8(7 Suppl): 325A. |
| Ng K.K.C., Poon R.T.P., Lam C.M., Yuen J., Tso W.K. and Fan S.T., Comparison of radiofrequency ablation and transarterial chemoembolization for unresectable hepatocellular carcinoma (Poster Presentation), The 19th World Congress of Digestive Surgery, Yokohama, Japan, 8-11 December 2004. |
| Ng K.K.C., Lam C.M., Poon R.T.P., Shek T.W.H., To J.Y.T., Wo Y.H., Ho D.W.Y. and Fan S.T., Comparison of systemic responses of radiofrequency ablation, cryotherapy, and surgical resection in a porcine liver model, Annals of Surgical Oncology. 2004, 11(7): 650-657. |
| Ng K.K.C., Poon R.T.P., Lam C.M. and Fan S.T., Initial experience of radiofrequency ablation for ruptured hepatocellular carcinoma (Abstract), Asian Journal of Surgery. 2005, 28(Suppl 2): S93. |
| Ng K.K.C., Poon R.T.P., Lam C.M. and Fan S.T., Initial experience of radiofrequency ablation for ruptured hepatocellular carcinoma (Abstract), Journal of Gastrointestinal Surgery. 2004, 8(7 Suppl): 151A. |
| Ng K.K.C., Poon R.T.P., Lam C.M. and Fan S.T., Initial experience of radiofrequency ablation for ruptured hepatocellular carcinoma (Abstract), The 19th World Congress of Digestive Surgery, Yokohama, Japan, 8-11 December 2004. |
| Ng K.K.C., Poon R.T.P., Lam C.M. and Fan S.T., Initial experience of radiofrequency ablation for ruptured hepatocellular carcinoma (Abstract), The 4th International Meeting on Hepatocellular Carcinoma: Eastern and Western Experiences, Hong Kong, 14-16 December 2004. |
| Ng K.K.C., Lam C.M., Poon R.T.P., Shek T.W.H., Ho D.W.Y. and Fan S.T., Maximal host tolerance to large-volume hepatic radiofrequency ablation in a rat model (Abstract), Journal of Gastrointestinal Surgery. 2004, 8( 7 Suppl): 114A. |
| Ng K.K.C., Lam C.M., Poon R.T.P., Shek T.W.H., Ho D.W.Y. and Fan S.T., Maximal host tolerance to large-volume hepatic radiofrequency ablation in a rat model (Abstract), The 19th World Congress of Digestive Surgery, Yokohama, Japan, 8-11 December 2004. |
| Ng K.K.C., Lam C.M., Poon R.T.P., Shek T.W.H., Yu W.C., To J.Y.T., Wo Y.H., Lau C.P.Y., Tang T.C.M., Ho D.W.Y. and Fan S.T., Porcine liver: morphological characteristics and cell viability at experimental radiofrequency ablation with internally cooled electrodes, Radiology. 2005, 235(2): 478-486. |
| Ng K.K.C., Poon R.T.P., Lam C.M., Yuen J., Tso W.K. and Fan S.T., Safety and efficacy of radiofrequency ablation for perivascular hepatocellular carcinoma without hepatic inflow occlusion (Abstract), The 6th Annual Scientific Meeting, Centre for the Study of Liver Disease, The University of Hong Kong, Hong Kong, 8 January 2005. |
| Ng K.K.C., Poon R.T.P., Lam C.M., Yuen J., Tso W.K. and Fan S.T., Safety and efficacy of radiofrequency ablation for perivascular hepatocellular carcinoma without inflow occlusion (Abstract), Journal of Gastrointestinal Surgery. 2004, 8(7 Suppl): 115A. |
| Ng K.K.C., Poon R.T.P., Lam C.M., Yuen J., Tso W.K. and Fan S.T., Safety and efficacy of radiofrequency ablation for perivascular hepatocellular carcinoma without inflow occlusion (Abstract), The 19th World Congress of Digestive Surgery, Yokohama, Japan, 8-11 December 2004. |
| Poon R.T.P., Fan S.T., Lo C.M., Liu C.L., Lam C.M., Yuen W.K., Yeung C. and Wong J., Improving perioperative outcome expands the role of hepatectomy in management of benign and malignant hepatobiliary diseases: analysis of 1222 consecutive patients from a prospective database, Annals of Surgery. 2004, 240(4): 698-708. |
| Tsang J., Ng K.K.C., Tung H., Yuen J., Poon R.T.P. and Lam C.M., Comparison of percutaneous RFA and hepatic resection for recurrent HCC (Abstract), The 12th Annual Scientific Meeting of Hong Kong College of Radiologists, Hong Kong, 30-31 October 2004. |
| Wong S.M.Y., Ng K.K.C., Poon R.T.P., Lam C.M., Yuen J., Tso W.K. and Fan S.T., Comparison of radiofrequency ablation and transarterial chemoembolisation for unresectable hepatocellular carcinoma (Abstract), Asian Journal of Surgery. 2005, 28(Suppl 2): S105. |
| Wong S.M.Y., Ng K.K.C., Poon R.T.P., Lam C.M., Yuen J., Tso W.K. and Fan S.T., Comparison of radiofrequency ablation and transarterial chemoembolisation for unresectable hepatocellular carcinoma (Abstract), The 4th International Meeting on Hepatocellular Carcinoma: Eastern and Western Experiences, Hong Kong, 14-16 December 2004. |
| Yong J.L., Lam C.M., Chan O.O., Poon R.T.P., Liu C.L., Lo C.M. and Fan S.T., Better survival in female patients with hepatocellular carcinoma (Abstract), Asian Journal of Surgery. 2005, 28(Suppl 2): S94. |
| Yong J.L., Lam C.M., Chan O.O., Poon R.T.P., Liu C.L., Lo C.M. and Fan S.T., Better survival in female patients with hepatocellular carcinoma (Abstract), The 4th International Meeting on Hepatocellular Carcinoma: Eastern and Western Experiences, Hong Kong, 14-16 December 2004. |
| Researcher : Lam CT |
| List of Research Outputs |
| Luk J.M.C., Lam C.T., Lam B.H., Siu A., Che C.M. and Fan S.T., Dyregulation of chaperone proteins Hsp27, Hsp70 and Grp78 in hepatocellular carcinoma (Abstract), The 3rd HUPO Annual World Congress, Beijing, China, 25-27 October . 2004. |
| Luk J.M.C., Lam C.T., Lam B.H., Siu A., Che C.M. and Fan S.T., Dysregulation of chaperone proteins Hsp27, Hsp70 and Grp78 in hepatocellular carcinoma, Molecular and Cellular Proteomics. 2004, 3(10): S114, 8.19. |
| Luk J.M.C., Lam B.K.Y., Lam C.T., Siu F.M., Ho D.W.Y., Yu W.C., Peng J.R., Che C.M., Leng X.S. and Fan S.T., Molecular classification of hepatocellular carcinoma by proteomic expression profiling (Abstract), The 6th Annual Scientific Meeting, Centre for the Study of Liver Disease, The University of Hong Kong, Hong Kong, 8 January 2005. |
| Luk J.M.C., Lee C.K.F., Su Y.C.F., Lam C.T., Hu M.Y., He Q., Lau G., Wong W.S. and Fan S.T., Proteomic identification of Ku70/Ku80 autoantigen recognized by monoclonal antibody against hepatocellular carcinoma (Abstract), HUPO 3rd Annual World Congress, Beijing, China, 25-27 October 2004. |
| Luk J.M.C., Su Y.C.F., Lam C.T., Lee C.K.F., Hu M.Y., He Q., Lau G., Wong F.W.S. and Fan S.T., Proteomic identification of Ku70/Ku80 autoantigen recognized by monoclonal antibody against hepatocellular carcinoma, Proteomics. 2005, 5(7): 1980-1986. |
| Yang Z., Ho D.W.Y., Lam C.T., Luk J.M.C., Lum C.T., Yu W.C., Poon R.T.P. and Fan S.T., Identification of brain-derived neurotrophic factor (BDNF) as a potential therapeutic target in hepatocellular carcinoma (Abstract), The 4th International Meeting on Hepatocellular Carcinoma: Eastern and Western Experiences, Hong Kong, 14-16 December 2004. |
| Yang Z., Ho D.W.Y., Lam C.T., Luk J.M.C., Yu W.C., Lo C.M., Poon R.T.P. and Fan S.T., Identification of brain-derived neurotrophic factor (BDNF) in hepatocellular carcinoma - from animal study to clinical management (Abstract), The 6th Annual Scientific Meeting, Centre for the Study of Liver Disease, The University of Hong Kong, Hong Kong, 8 January 2005. |
| Yang Z., Ho D.W.Y., Lam C.T., Luk J.M.C., Lum C.T., Yu W.C., Poon R.T.P. and Fan S.T., Identification of brain-derived neurotrophic factor as a novel functional protein in hepatocellular carcinoma, Cancer Research. 2005, 65(1): 219-225. |
| Yang Z., Ho D.W.Y., Lam C.T., Luk J.M.C., Poon R.T.P. and Fan S.T., The potential role of allograft inflammatory factor 1 (AIF-1) in macrophage activation in small-for-size liver transplantation, The 20th International Congress of the Transplantation Society, Vienna, Austria, 5-10 September 2004. |
| Researcher : Lam LK |
| List of Research Outputs |
| Chan H.H.L., Wong S.Y., Ho W.S., Lam L.K. and Wei W.I., The use of pulsed dye laser for the prevention and treatment of hypertrophic scars in Chinese persons, Dermatologic Surgery. 2004, 30: 987-994. |
| Lam L.K., Annual Scientific Meeting/AGM2005. |
| Lam L.K., Hands-on workshop - facial fracture plating, International Comprehensive Head and Neck Course 2004, Guiyang, Guizhou, China, November 2004. |
| Lam L.K., Latissimus dorsi myocutaneous flap, Hong Kong Master Class in Plastic Reconstructive and Aesthetic Surgery, Hong Kong, April 2005. |
| Lam L.K., Live Surgery demonstration - myocutaneous or deltopectoral flap, Hong Kong Master Class in Plastic Reconstructive and Aesthetic Surgery, Hong Kong April 2005. |
| Lam L.K., Member of Editorial Board, Chinese Journal of Burns - (Zhonghua Shaoshang Zazhi), Chinese Medical Association. 2005. |
| Lam L.K., Mucosal melanoma of the head and neck in a chinese population, SVIII IFOS World Congress, Rome, Italy, June 2005. |
| Lam L.K., PM flap complication and results, Hong Kong Master Class in Plastic Reconstructive and Aesthetic Surgery, Hong Kong, April 2005. |
| Lam L.K., PM flap technique, Hong Kong Master Class in Plastic Reconstructive and Aesthetic Surgery, Hong Kong, April 2005. |
| Lam L.K., Reconstruction & Rehabilitation in Head & Neck Surgery - Pedicle Flaps, Hong Kong, June 2005, Head & Neck Course 2005. |
| Lam L.K., Surgical treatment for late effects of radiotheraphy in soft tissues and bones, Head and Neck Society Scientific Meeting, Hong Kong, September 2004. |
| Lam L.K., Lam L.K. and Lam L.K., Tips and Tricks in Head and Neck Reconstruction, The 2005 Hong Kong Master Class in Plastic Reconstructive and Aewsthetic Surgery Hong Kong, April 2005. |
| Lam L.K., Tips and tricks in head and neck reconstruction, International Comprehensive Head and Neck Course 2004, Guiyang uizhou, China, November 2004. |
| Lam L.K., Trapezius myocutaneous flap, Hong Kong Master Class in Plastic Reconstructive and Aesthetic Surgery, Hong Kong, April 2005. |
| Researcher : Lamb JR |
| List of Research Outputs |
| Chan V.S.F., Chau S.Y., Tian L., Kwong S.K.Y., Quackenbush J., Dallman M., Lamb J.R. and Tam P.K.H., Sonic hedgehog promotes CD4+ T lymphocyte proliferation by modulating a subset of CD28-targeted genes, 9th Basic Science Symposium of the Transplantation Society, LaBaule, France, 19-22 June 2005. |
| Li X., Tian L., Lamb J.R. and Tam P.K.H., Anti-TGF-beta prevents chronic rejection in a rat orthotopic small bowel transplantation model, IXth International Small Bowel Transplantation Symposium, Brussels, Belgium, 30 June - 2 July 2005. |
| Tam P.K.H., Tian L., Li X. and Lamb J.R., Inhibition of sonic hedgehog signaling reduces chronic allograft rejection in rat small bowel transplantation, IXth International Small Bowel Transplantation Symposium, Brussels, Belgium, 30 June - 2 July 2005. |
| Tam P.K.H., Tian L., Li X., Dallman M. and Lamb J.R., Inhibition of sonic hedgehog singaling reduces chronic allograft rejection in rat small bowel transplantation, 9th Basic Science Symposium of the Transplantation Society, LaBaule, France, 19-22 June 2005. |
| Tian L., Yuan Z., Cai Q., Lui Y., Thompson P., Tam P.K.H. and Lamb J.R., Combined treatment with cyclosporin A and rosiglitazone prevents chronic allograft rejection, 9th Basic Science Symposium of the Transplantation Society, LaBaule, France, 19-22 June 2005. |
| Tian L., Lui Y., Lamb J.R. and Tam P.K.H., The effect of blocking CD28 and CD134 co-stimulatory pathways in rat cardiac transplant, 9th Basic Science Symposium of the Transplantation Society, LaBaule, France, 19-22 June 2005. |
| Researcher : Lau AMF |
| List of Research Outputs |
| Garcia-Barcelo M.M., Ganster R.W., Lui V.C.H., Leon Y.Y., So M.T., Lau A.M.F., Fu M., Sham M.H., Knight J., Zannini M.S., Sham P.C. and Tam P.K.H., TTF-1 and RET promoter SNPs: regulation of RET transcription in Hirschsprung's disease, Human Molecular Genetics. 2005, 14(2): 191-204. |
| Lau A.M.F., Regulation of gene expression by NF-kB and stats downstream of ret receptor tyrosine kinase in Hirschsprung's disease and thyroid cancer, Thesis, Master of Philosophy, The University of Hong Kong. 2004. |
| Researcher : Lau CK |
| List of Research Outputs |
| Ho D.W.Y., Yang Z., Lau C.K., To J.Y.T., Luk J.M.C. and Fan S.T., The therapeutic role of cardiotrophin-1 in a rat model with fulminant hepatic failure (Abstract), The 6th Annual Scientific Meeting, Centre for the Study of Liver Disease, The University of Hong Kong, Hong Kong, 8 January 2005. |
| Poon R.T.P., Yang Z., Liu Y., Ho D.W.Y., Lau C.K. and Fan S.T., Blockade of vascular endothelial growth factor (VEGF) receptor enhances the therapeutic efficacy and chemotherapy in hepatocellular carcinoma (Abstract), The 96th Annual Meeting of the American Association for Cancer Research, Anaheim, California, U.S.A., 16-20 April 2005. |
| Researcher : Lau CPY |
| List of Research Outputs |
| Lau C.P.Y., SPARC and SPARC-like 1 are associated with Tumor Angiogenesis in Hepatocellular Carcinoma, Thesis, Master of Philosophy, The University of Hong Kong. 2004. |
| Liu Y., Poon R.T.P., Li Q., Kok T.W., Lau C.P.Y. and Fan S.T., Both antiangiogenesis- and angiogenesis-independent effects are responsible for hepatocellular carcinoma growth arrest by tyrosine kinase inhibitor PTK787/ZK222584, Cancer Research. 2005, 65(9): 3691-3699. |
| Ng K.K.C., Lam C.M., Poon R.T.P., Shek T.W.H., Yu W.C., To J.Y.T., Wo Y.H., Lau C.P.Y., Tang T.C.M., Ho D.W.Y. and Fan S.T., Porcine liver: morphological characteristics and cell viability at experimental radiofrequency ablation with internally cooled electrodes, Radiology. 2005, 235(2): 478-486. |
| Poon R.T.P., Ho J.W.Y., Tong C.S.W., Lau C.P.Y., Ng I.O.L. and Fan S.T., Prognostic significance of serum vascular endothelial growth factor and endostatin in patients with hepatocellular carcinoma, British Journal of Surgery. 2004, 91(10): 1354-1360. |
| Tang T.C.M., Poon R.T.P., Lau C.P.Y., Xie D. and Fan S.T., Cytosolic cyclooxygenase-2 levels correlate with cytosolic vascular endothelial growth factor levels and tumor invasiveness in human hepatocellular carcinoma (Abstract), The 1st Annual Conference for the Organisation for Oncology and Translational Research, Hong Kong, 15-16 October 2004. |
| Tang T.C.M., Poon R.T.P., Lau C.P.Y., Xie D. and Fan S.T., Tumor cyclooxygenase-2 levels correlate with tumor invasiveness in human hepatocellular carcinoma, World Journal of Gastroenterology. 2005, 11(13): 1896-1902. |
| Researcher : Lau H |
| List of Research Outputs |
| Chok K.S.H., Yuen W.K., Lau H., Lee F.C.W. and Fan S.T., Outpatient laparoscopic cholecystectomy in Hong Kong Chinese - an outcome analysis, Asian Journal of Surgery. 2004, 27(4): 313-316. |
| Chok S.H., Yuen W.K., Lau H., Lee F.C.W. and Fan S.T., Outpatient laparoscopic cholecystectomy - a review of 135 consecuttive patients (Abstract), Surgical Practice. 2005, 9 (Supplement): S8. |
| Chok S.H., Yuen W.K., Lau H. and Lee F.C.W., Outpatient laparoscopic cholecystectomy: a reivew of 135 consecutive patients, Endoscopic & Laparoscopic Surgeons of Asia Regional Meeting and 4th World Congress of Gasless Laparoscopic Surgery, Bali, Indonesia, 26-29 September 2004. |
| Lau H., 2nd Best Winner, Ibrahim Abmadsyah Best Post Award, Endoscopic & Laparoscopic Surgeons of Asia Regional Meeting and 4th World Congress of Gasless Laparoscopic Surgery, Bali, Indonesia, 26 - 29 September 2004. 2004. |
| Lau H., A prospective comparative study of endoscopic totally extraperitoneal inguinal hernioplasty for primary and recurrent hernia, Endoscopic & Laparoscopic Surgeons of Asia Regional Meeting and 4th World Congress of Gasless Laparoscopic Surgery, Bali, Indonesia, 26 - 29 September 2004. |
| Lau H., A systemic review of early versus late laparoscopic cholecystectomy for acute cholecystitis (poster), 2005 Annual Meeting, Society of American Gastrointestinal Endoscopic Surgeons (SAGES), Florida, U.S.A., 12-16 April 2005. |
| Lau H., Chairman, 19th World Congress of International Society for Digestive Surgery, Pacifico Yokohama Conference Center, Yokohama, Japan, 9-11 December 2004. 2004. |
| Lau H., Controversies of laparoscopic versus open inguinal hernioplasty (Invited), 2005 Annual Symposium of Macao Surgery Association, Macau, 19 June 2005. |
| Lau H., Council Member (2004 - 2005), Hong Kong Association of Day Surgery. 2005. |
| Lau H., Council Member (2004 - 2005), Hong Kong Society of Minimal Access Surgery. 2005. |
| Lau H., Day case laparoscopic cholecystectomy: keys to success (Invited Keynote Lecture), 19th World Congress of International Society for Digestive Surgery, Yokohama, Japan, 8-11 December 2004. |
| Lau H., Day case laparoscopic cholecystectomy: keys to success, Journal of Gastrointestinal Surgery. 2004, 8: 56A. |
| Lau H., Early versus delayed interval laparoscopic cholecystectomy for acute cholecystitis; a meta-analysis (Abstract), Surgical Endoscopy. 2005, 19: S247. |
| Lau H., Endoscopic totally extraperitoneal inguinal hernioplasty for recurrence after open repair, Australian New Zealand Journal of Surgery. 2004, 74: 877-880. |
| Lau H., Wong C., Chu K. and Patil N.G., Endoscopic totally extraperitoneal inguinal hernioplasty under general anesthesia, Endoscopic & Laparoscopic Surgeons of Asia Regional Meeting and 4th World Congress of Gasless Laparoscopic Surgery, Bali, Indonesia, 26 - 29 September 2004. |
| Lau H., Wong C., Chu K. and Patil N.G., Endoscopic totally extraperitoneal inguinal hernioplasty under spinal anesthesia, Journal of Laparoendoscopic & Advanced Surgical Techniques. 2005, 15(2): 121-124. |
| Lau H., Faculty Member, Basic Laparoscopic Surgery Course, Hospital Authority, Pamela Youde Nethersole Eastern Hospital, 2-3 November 2004. 2004. |
| Lau H., Fibrin sealant vs mechanical stapling for mesh fixation during endoscopic inguinal hernioplasty; a prospective randomized trial, 90th Annual Clinical Congress of American College of Surgeons, New Orleans, U.S.A., 10-14 October 2004. |
| Lau H., Hernia repair (Invited), Postgraduate Course, Surgical Practice 2005, 12th Annual Scientific Meeting, The Colleg e of Surgeons of Hong Kong, Hong Kong, 4-5 June 2005. |
| Lau H. and Patil N.G., Impact of previous appendectomy on the outcomes of endoscopic totally extraperitoneal inguinal hernioplasty, Surgical Laparoscopy, Endoscopy & Percutaneous Techniques. 2004, 14(5): 257-259. |
| Lau H., Is endoscopic totally extraperitoneal hernioplasty (TEP) justified for the repair of groin hernia in female patients? (Abstract), Surgical Endoscopy. 2005, 19: S193. |
| Lau H., Is endoscopic totally extraperitoneal hernioplasty justified for the repair of groin hernia in female patients? (oral), 2005 Annual Meeting, Society of American Gastrointestinal Endoscopic Surgeons (SAGES), Florida, U.S.A., 12-16 April 2005. |
| Lau H., Laparoscopic repair of incisional hernia, Symposium on "Incisional Hernia", The College of Surgeons of Hong Kong, Hong Kong, 4 October 2004. |
| Lau H., Laparoscopic repair of perforated peptic ulcer. A meta-analysis, Surgical Endoscopy. 2004, 18: 1013-1021. |
| Lau H., Management of postoperative urinary retention: a randomized trial of in-out versus overnight catheterization, Australian and New Zealand Journal of Surgery. 2004, 74: 658-661. |
| Lau H., Member (2004 - present), Committee for Coordination of Minimal Access Surgery Training, Hospital Authority. 2005. |
| Lau H., Member of Editorial Board, Cutting Edge, College of Surgeons of Hong Kong. 2005. |
| Lau H., Operative techniques for the closure of peritoneal tear during endoscopic totally experitoneal inguinal hernioplasty (video), 2005 Annual Meeting, Society of American Gastrointestinal Endoscopic Surgeons (SAGES), Florida, U.S.A., 12-16 April 2005. |
| Lau H., Organizer, Advanced Laparoscopic Gastrointestinal Surgery Course with Hands-on Cadaver Dissection, in collaboration with Department of Anatomy, The University of Hong Kong, Hong Kong, 17-18 June 2005. 2005. |
| Lau H., Organizing Committee Member (2004 - 2005), 7th Asian Pacific Congress of Endoscopic Surgery, ELSA 2005, Hong Kong, 17-19 August 2005. 2005. |
| Lau H., Outcomes of 1,000 consecutive endoscopic totally extraperitoneal inguinal hernioplasty, Asian Journal of Surgery. 2005, 28 (Supplement I): 26. |
| Lau H., Patil N.G. and Yuen W.K., Outcomes of laparoscopic incisional hernia repair: A prospective evaluation, Surgical Practice. 2005, 9: 13-17. |
| Lau H., Patients' perception of open and endoscopic extraperitoneal inguinal hernioplasty, Surgical Laparoscopic Endoscopic Percutaneous Technology. 2004, 14(4): 219-221. |
| Lau H., Reviewer , Asian Journal of Surgery. 2005. |
| Lau H., Reviewer, Annals of the College of Surgeons of Hong Kong. 2004. |
| Lau H., Reviewer, Surgical Practice. 2005. |
| Lau H., Tutor, Intercollegiate Basic Surgical Skills Course, Princess Margaret Hospital, Hong Kong, 16-18 September 2004. 2004. |
| Lau H., Which hernia repair for your patient?, Surgical Practice. 2005, 9: 12. |
| Lau H., 應用Goretex Dualmesh的腹腔切口疝根治術(Abstract), Proceedings of 廣東省醫學會微創外科第二屆學術研討會暨深圳市微創外科第三屆年會, 2005. |
| Researcher : Law SYK |
| Project Title: | The use of combined Lutetium Oxyorthosilicate (LSO) Positron Emission Scan and CT scan in staging of esophageal cancer. |
| Investigator(s): | Law SYK, Sham JST, Ooi CGC, Kwong DLW, Wong J, Yau Y.Y., Yeung A. |
| Department: | Surgery |
| Source(s) of Funding: | Other Funding Scheme |
| Start Date: | 03/2002 |
| Abstract: |
| To analysis the use of combined Lutetium Oxyorthosilicate (LSO) Positron Emission Scan and CT scan in staging of esophageal cancer. |
| List of Research Outputs |
| Chen C.T.H. and Law S.Y.K., Prognostic factors for long-term survival in patients with cancer of the gastric cardia (Dissertation), Master Degree in Medical Sciences, The University of Hong Kong, August. 2004. |
| Cheng W., Poon K.H., Lui V.C.H., Yong J.L., Law S.Y.K., So K.T., Tse K. and Tam P.K.H., Esophageal atresia and achalasia like esophageal dysmotility, Journal of Pediatric Surgery. 2004, 39(10): 1581-1583. |
| Chu K.M., Kwok K.F., Law S.Y.K. and Wong K.H., Patients with Helicobacter pylori positive and negative duodenal ulcers have distinct clinical characteristics, World Journal of Gastroenterology . 2005, 11(23): 3518-3522. |
| Fatima S., Hui K.S., Wong M.M., Tang W.K., Chui C.H., Wong J., Law S.Y.K., Tsao G.S.W., Lam K.Y., Srivastava G., Ho K.P. and Tang J.C.O., Study of transforming capacity of two novel genes JS-1 and JS-2 in chromosome 5p and their overexpression in human esophageal squamous cell carcinoma, 96th Annual Meeting of the American Association for Cancer Research, Anaheim, California, USA, 16-20 April. 2005. |
| Ferri L.E., Lee J.K.T., Law S.Y.K., Wong K.H., Kwok K.F. and Wong J., Management of spontaneous perforation of esophageal cancer with covered self expanding metallic stents (Case Report), Diseases of the Esophagus. 2005, 18(1): 67-69. |
| Ferri L.E., Law S.Y.K., Wong K.H., Kwok K.F. and Wong J., The impact of technical complications on short term adverse outcomes and survival after esophagectomy (Abstract), 19th World Congress of International Society for Digestive Surgery, Yokohama, Japan, 8-11 December. 2004. |
| Ferri L.E., Law S.Y.K., Wong K.H., Kwok K.F. and Wong J., The impact of technical complications on short term adverse outcomes and survival after esophagectomy (Abstract), Journal of Gastrointestinal Surgery. 2004, 8(Supplement 7S): 76A. |
| Law S.Y.K., Suen D.T.K., Wong K.H., Kwok K.F. and Wong J., A single-layer, continuous, hand-sewn method for esophageal anastomosis - prospective evaluation in 218 patients, Archives of Surgery. 2005, 140(1): 33-39. |
| Law S.Y.K., Achalasia - current management (Abstract), Asian Pacific Digestive Week 2004, Beijing, China, 4-7 October. 2004. |
| Law S.Y.K., Carcinoma of the esophagus - evidence-based surgery (Abstract), Asian Pacific Digestive Week 2004, Beijing, China, 4-7 October. 2004. |
| Law S.Y.K., Chemoradiation therapy for esophageal cancer: impact on management (Abstract), 60th Clinical Congress of the Philippine College of Surgeons, Mandaluyong City, 5-8 Decmeber. 2004. |
| Law S.Y.K., Combined modality treatments for esophageal cancer: current status, Joint Beijing / Hong Kong Surgical Forum, Beijing Union Hospital, Chinese Academy of Medicine, Beijing, China, 11-12 July. 2004. |
| Law S.Y.K., Combined modality treatments for esophageal cancer: current status, Lecture on "Esophageal Cancer Treatment" in Toranomon Hospital, Tokyo, Japan, 17 August. 2004. |
| Law S.Y.K., Complications after esophagectomy, inevitable but salvageable (Interactive Workshop), 31st Annual Toronto Thoracic Surgery Refresher Course, Toronto, Canada, 27-28 May. 2005. |
| Law S.Y.K. and Wong J., Complications of esophageal resection: not preventable but not fatal (Abstract), 59th Annual Meeting of the Japanese Society of Gastroenterological Surgery, Kagoshima, Japan, 21-23 July. 2004. |
| Law S.Y.K. and Wong J., Complications of esophageal resection: not preventable but not fatal (Abstract), The Japanese Journal of Gastroenterological Surgery. 2004, 37(7): 195. |
| Law S.Y.K. and Wong J., Current management of esophageal cancer (Review Article), Journal of Gastrointestinal Surgery. 2005, 9(2): 291-310. |
| Law S.Y.K., Current status of combined modality treatments for esophageal cancer, Hong Kong Surgical Forum, Department of Surgery, University of Hong Kong Medical Centre, Hong Kong, 9-10 July. 2004. |
| Law S.Y.K. and Wong J., Current status of esophageal cancer treatment in Asia, Esophagus. 2004, 1(4): 169-176. |
| Law S.Y.K., Endoscopic stenting for esophageal cancer, 31st Annual Toronto Thoracic Surgery Refresher Course, Toronto, Canada, 27-28 May. 2005. |
| Law S.Y.K., Esophageal Surgery, Certificate Course in ICU Nursing, HKU SPACE, The University of Hong Kong, June. 2005. |
| Law S.Y.K., Esophageal Surgery, Post-Registration Certificate Course in Peri-operative Nursing, Hospital Authority, April. 2005. |
| Law S.Y.K. and Wong J., Esophageal cancer surgery: lessons from 1,200 resections, Hawaii Medical Journal. 2004, 63(7): 203-205. |
| Law S.Y.K., Esophageal cancer: update in management (Abstract), Alimentary Disease Weekend, Department of Surgery, University of Hong Kong Medical Centre, Hong Kong, 18-19 September. 2004. |
| Law S.Y.K., Evolving strategies in the treatment of esophageal cancer (Special Symposium), 59th Annual Meeting of the Japanese Society of Gastroenterological Surgery, Kagoshima, Japan, 21-23 July. 2004. |
| Law S.Y.K., GB Ong Traveling Fellowship, The University of Hong Kong. 2004. |
| Law S.Y.K., Management of complicated cases of esophageal cancer (Abstract), 60th Clinical Congress of the Philippine College of Surgeons, Mandaluyong City, 5-8 December. 2004. |
| Law S.Y.K., Management of complications after esophagectomy, 31st Annual Toronto Thoracic Surgery Refresher Course, Toronto, Canada, 27-28 May. 2005. |
| Law S.Y.K., Management of patients with esophageal cancer, Post-Registration Certificate Course in Intensive Care Nursing, Hospital Authority, April. 2005. |
| Law S.Y.K., Member of Editorial Board (1999 - present), Diseases of the Esophagus. 2005. |
| Law S.Y.K., Member of Editorial Board (2002 - present), Chinese Journal of Gastrointestinal Surgery. 2005. |
| Law S.Y.K., Member of Editorial Board (2005 - present), World Journal of Surgery. 2005. |
| Law S.Y.K., Member, International Advisory Board (2003 - present), Esophagus. 2005. |
| Law S.Y.K., Minimally invasive esophagectomy: current evidence, Advanced Laparoscopic Gastrointestinal Surgery Course, Department of Surgery, University of Hong Kong Medical Centre, Queen Mary Hospital, 17-18 June. 2005. |
| Law S.Y.K., Neoadjuvant therapy for carcinoma of the esophagus (Royal College of Physicians and Surgeons of Canada Lecture), 31st Annual Toronto Thoracic Surgery Refresher Course, Toronto, Canada, 27-28 May. 2005. |
| Law S.Y.K., Kwong D.L.W., Wong K.H., Kwok K.F., Sham J.S.T. and Wong J., Oesophageal cancer located above the tracheal bifurcation is an independent poor prognostic factor. Neoadjuvant chemoradiation improves survival (Abstract), Gut. 2004, 53 (Supplement VI): A279-A280. |
| Law S.Y.K., Kwong D.L.W., Wong K.H., Kwok K.F., Sham J.S.T. and Wong J., Oesophageal cancer located above the tracheal bifurcation is an independent poor prognostic factor. Neoadjuvant chemoradiation improves survival (Abstract), The 12th United European Gastroenterology Week, Prague, Czech Republic, 25-29 September. 2004. |
| Law S.Y.K., Wong K.H., Kwok K.F., Chu K.M. and Wong J., Predictive factors for postoperative pulmonary complications and mortality after esophagectomy for cancer, Annals of Surgery. 2004, 240(5): 791-800. |
| Law S.Y.K., Thoracoscopic esophagectomy for esophageal cancer (Abstract), 19th World Congress of International Society for Digestive Surgery, Yokohama, Japan, 8-11 December. 2004. |
| Law S.Y.K., Thoracoscopic esophagectomy for esophageal cancer (Abstract), Journal of Gastrointestinal Surgery. 2004, 8(Supplement 7S): 25A. |
| Law S.Y.K., Treatment strategy of esophageal cancer (Seminar Panel Discussion), 19th World Congress of International Society for Digestive Surgery, Yokohama, Japan, 8-11 December. 2004. |
| Law S.Y.K., Upper gastrointestinal anastomosis (Symposium on GI anastomosis), The College of Surgeons of Hong Kong, Hospital Authority, July. 2004. |
| Law S.Y.K., 食管癌: Understanding the treatments and its care for cancer of the esophagus, Cancer Centre, Queen Mary Hospital, May. 2005. |
| Leung S.Y., Yuen S.T., Chu K.M., Mathy J.A., Li R., Chan A.S.Y., Law S.Y.K., Wong J., Chen X. and So S., Expression profiling identifies chemokine (C-C motif) ligand 18 as an independent prognostic indicator in gastric cancer, Gastroenterology. 2004, 127(2): 457-469. |
| Mok V.W.K., Ting A.C.W., Law S.Y.K., Wong K.H., Cheng S.W.K. and Wong J., Combined endovascular stent grafting and endoscopic injection of fibrin sealant for aortoenteric fistula complicating esophagectomy, Journal of Vascular Surgery. 2004, 40(6): 1234-1237. |
| Yang L., Leung A.C.C., Ko J.M.Y., Lo P.H.Y., Tang J.C.O., Srivastava G., Oshimura M., Stanbridge E.J., Daigo Y., Nakamura Y., Tang C.M.C., Lau K.W., Law S.Y.K. and Lung M.L., Tumor suppressive role of a 2.4 Mb 9q33-q34 critical region and DEC1 in esophageal squamous cell carcinoma, Oncogene. 2005, 24(4): 697-705. |
| Researcher : Law WL |
| Project Title: | Self-expanding metallic stents for the poor patients with malignant colorectal obstruction |
| Investigator(s): | Law WL, Chu KW |
| Department: | Surgery |
| Source(s) of Funding: | S.K. Yee Medical Foundation - General Award |
| Start Date: | 04/2004 |
| Abstract: |
| To provide the insertion of self-expanding metallic stents to the poor patients who cannot afford the devices. |
| List of Research Outputs |
| Cheung T.T., Law W.L., Ho J.W.C., Lee Y.M., Seto C.L. and Choi H.K., Outcome of synchronous cystectomy in patients with advanced primary colorectal cancer, 19th World Congress of ISDS, Yokohama, Japan, 8-11 December 2004. |
| Cheung T.T., Law W.L., Ho J.W.C., Lee Y.M., Seto C.L. and Choi H.K., Outcome of synchronous cystectomy in patients with advanced primary colorectal cancer, Journal of Gastrointestinal Surgery. 2004, 8, No. 7S: 191A-P60. |
| Chik B. and Law W.L., Stapled hemorrhoidectomy is associated with a lower incidence of urinary retention, 19th World Congress of ISDS, Yokohama, Japan, 8-11 December 2004. |
| Chik B. and Law W.L., Stapled hemorrhoidectomy is associated with a lower incidence of urinary retention, Journal of Gastrointestinal Surgery. 2004, 8, No. 7S: 191A-P62. |
| Choi H.K., Law W.L., Ho J.W.C. and Chu K.W., Value of gastrografin in adhesive small bowel obstruction after unsuccessful conservative treatment: a prospective evaluation, World Journal of Gastroenterology. 2005, 11 (24): 3742-3745. |
| Law W.L. and Chu K.W., Abdominoperineal resection is associated with poor oncological outcome, British Journal of Surgery. 2004, 91(11): 1493-1499. |
| Law W.L. and Chu K.W., Anterior resection for rectal cancer with mesorectal excision: a prospective evaluation of 622 patients, Annals of Surgery. 2004, 240(2): 260-268. |
| Law W.L., Controversies in surgical treatment of rectal cancer - low anterior resection with TME/PME: role of radiation or chemotherapy, 2005 Yonsei Colorectal Cancer International Symposium, Souel, Korea, 18 May 2005. |
| Law W.L., Current evidence of laparoscopic resection for colorectal cancer, Advanced Laparoscopic Gastrointestinal Surgery Course, Department of Surgery, Hong Kong, 16-17 June 2005. |
| Law W.L., Laparoscopic rectal surgery, Advanced Laparoscopic Gastrointestinal Surgery Course, Department of Surgery, Hong Kong, 16-17 June 2005. |
| Law W.L., Ho J.W.C., Chan T.T., Au G.K.H. and Chu K.W., Outcome of anterior resection for stage II rectal cancer without radiation: the role of adjuvant chemotherapy, Diseases of the Colon & Rectum. 2005, 48(2): 218-226. |
| Law W.L., Rectal cancer today: Asian experiences, 2005 Yonsei Colorectal Cancer International Symposium, Souel, Korea, 18 May 2005. |
| Law W.L., Ng K.C., Lee Y.M., Ho J.W.C., Choi H.K. and Seto C.L., Self-expanding metallic stent as a bridge to surgery versus emergency operation for obstructing left sided colorectal cancer: a case-matched study, Digestive Disease Week, Chicago, USA, 16-19 May 2005. |
| Law W.L., Ng K.C., Ng K.C., Lee Y.M., Ho J.W.C., Choi H.K. and Seto C.L., Self-expanding metallic stent as a bridge to surgery versus emergency operation for obstructing left sided colorectal cancer: a case-matched study, Gastroenterology. 2005, 128 (4): A799, Suppl. 2. |
| Law W.L., Temporary ileostomy versus temporary colostomy: a meta-analysis of complications (Invited commentary), Asian Journal of Surgery. 2004, 27(3): 211-212. |
| Law W.L., Tutor, hand on cadaver course, Advanced Laparoscopic Gastrointestinal Surgery Course, Department of Surgery, Hong Kong, 16-17 June 2005. |
| Lee Y.M. and Law W.L., Survival and pattern of recurrence after curative resection of colorectal cancer: review of 1064 patients in a single institution, 19th World Congress of ISDS, Yokohama, Japan, 8-11 December 2004. |
| Lee Y.M. and Law W.L., Survival and pattern of recurrence after curative resection of colorectal cancer: review of 1064 patients in a single institution, Journal of Gastrointestinal Surgery. 2004, 8, No. 7S: 102A-FP134. |
| Lo S.H. and Law W.L., Laparoscopic resection for colorectal polyps not suitable for colonoscopic removal, 19th World Congress of ISDS, Yokohama, Japan, 8-11 December 2004. |
| Lo S.H. and Law W.L., Laparoscopic resection for colorectal polyps not suitable for colonoscopic removal, Journal of Gastrointestinal Surgery. 2004, 8, No. 7S: 284A-P-387. |
| Poon J., Chan B. and Law W.L., Evaluation of P-possum in surgery for obstructing colorectal cancer and correlation of the predicted mortality with different surgical options, Diseases of the Colon & Rectum. 2005, 48(3): 493-498. |
| Researcher : Lee CKF |
| List of Research Outputs |
| Luk J.M.C., Lee C.K.F., Su Y.C.F., Lam C.T., Hu M.Y., He Q., Lau G., Wong W.S. and Fan S.T., Proteomic identification of Ku70/Ku80 autoantigen recognized by monoclonal antibody against hepatocellular carcinoma (Abstract), HUPO 3rd Annual World Congress, Beijing, China, 25-27 October 2004. |
| Luk J.M.C., Su Y.C.F., Lam C.T., Lee C.K.F., Hu M.Y., He Q., Lau G., Wong F.W.S. and Fan S.T., Proteomic identification of Ku70/Ku80 autoantigen recognized by monoclonal antibody against hepatocellular carcinoma, Proteomics. 2005, 5(7): 1980-1986. |
| Luk J.M.C., Lee C.K.F., Wang X. and Fan S.T., Recognition of monoclonal antibodies against alternative splicing of liver intestine cadherin (Cdh17) in hepatocellular carcinoma , The 34th Annual Scientific Meeting of the Australasian Society for Immunology and 8th International Conference on Human Leucocyte Differentiation Antigens (HLDA8), Adelaide, Australia, 12-16 December 2004. |
| Researcher : Lee FCW |
| List of Research Outputs |
| Cheung M.C., Lee F.C.W., Chu S.S.M., Leung S.Y.L., Wong B.B.W., Ho K.L. and Tam P.C., Laparoscopic nephrectomy: an early experience at Queen Mary Hospital, Hong Kong Medical Journal. 2005, 11(1): 7-11. |
| Chok K.S.H., Yuen W.K., Lau H., Lee F.C.W. and Fan S.T., Outpatient laparoscopic cholecystectomy in Hong Kong Chinese - an outcome analysis, Asian Journal of Surgery. 2004, 27(4): 313-316. |
| Chok S.H., Yuen W.K., Lau H., Lee F.C.W. and Fan S.T., Outpatient laparoscopic cholecystectomy - a review of 135 consecuttive patients (Abstract), Surgical Practice. 2005, 9 (Supplement): S8. |
| Chok S.H., Yuen W.K., Lau H. and Lee F.C.W., Outpatient laparoscopic cholecystectomy: a reivew of 135 consecutive patients, Endoscopic & Laparoscopic Surgeons of Asia Regional Meeting and 4th World Congress of Gasless Laparoscopic Surgery, Bali, Indonesia, 26-29 September 2004. |
| Leung S.Y.L., Wong B.B.W., Cheung M.C., Lee F.C.W. and Tam P.C., A phase II trial of continuous, oral low-dose estramustine and etoposide chemotherapy in the treatment of symptomatic hormone-refractory prostate cancer (HRCP), International Journal of Urology. 2004, 11(Suppl): A16. |
| Leung S.Y.L., Wong B.B.W., Cheung M.C., Lee F.C.W. and Tam P.C., Day case transurethral resection - vaporization of the prostate (TURVP) for the treatment of benign prostatic hyperplasia - a prospective trial, International Journal of Urology. 2004, 11(Suppl): A13. |
| Leung S.Y.L., Chan A.C.Y., Wong B.B.W., Cheung M.C., Lee F.C.W. and Tam P.C., Management of febrile urinary tract infections (UTI) complicating transrectal ultrasound guided biopsy of the prostate (TRUSBx), International Journal of Urology. 2004, 11(Suppl): A19. |
| Leung S.Y.L., Wong B.B.W., Ho K.L., Cheung M.C., Lee F.C.W. and Tam P.C., Prospective double-blind randomized controlled trial on intrarectal administration of lidocaine gel vs. plain lubricant gel for pain control during transrectal ultrasound guided extensive 10-core prostate biopsy, International Journal of Urology. 2004, 11(Suppl): A9. |
| Leung S.Y.L., Cheung M.C., Wong B.B.W., Lee F.C.W. and Tam P.C., Transurethral ethanol ablation of the prostate (TEAP) for the management of acute retention of urine in patients with compromised medical risks, International Journal of Urology. 2004, 11(Suppl): A48-A49. |
| Tsu H.L., Cheung M.C., Chu S.S.M., Lee F.C.W. and Tam P.C., Laparoscopic live donor nephrectomy: is there any difference in outcome compared with its conventional open counterpart?, International Journal of Urology. 2004, 11(Suppl): A4. |
| Wong B.B.W., Cheung M.C., Leung S.Y.L., Lee F.C.W. and Tam P.C., A prospective, randomized study comparing transurethral resection of prostate (TURP) with transurethral resection - vaporization of prostate (TURVP) on treatment for acute urinary retention, International Journal of Urology. 2004, 11(Suppl): A11-A12. |
| Researcher : Lee KW |
| List of Research Outputs |
| Lee K.W., Man K., Poon R.T.P., Lo C.M., Ng I.O.L. and Fan S.T., Disruption of p53-p21/WAF1 cell cycle pathway contributes to progression and worse clinical outcome of hepatocellular carcinoma, Oncology Reports. 2004, 12(1): 25-31. |
| Lee K.W., Man K., Ho J.W.Y., Sun K.W., Ng T.P., Wang X., Wong Y.C., Ng I.O.L., Xu R. and Fan S.T., FTY720 induces apoptosis of human hepatoma cell lines through PI3-K-mediated Akt dephosphorylation, Carcinogenesis. 2004, 25(12): 2397-2405. |
| Lee K.W., Man K. and Fan S.T., Significance of Rac signaling pathway in HCC cell motility: implication for a new therapeutic treatment (Abstract), Asian Journal of Surgery. 2005, 28(Suppl 2): S90. |
| Lee K.W., Man K. and Fan S.T., Significance of Rac signaling pathway in HCC cell motility: implication for a new therapeutic treatment (Abstract), The 4th International Meeting on Hepatocellular Carcinoma: Eastern and Western Experiences, Hong Kong, 14-16 December 2004. |
| Lee K.W., Man K. and Fan S.T., Significance of Rac signaling pathway in hepatocellular carcinoma cell motility: implication for a new therapeutic treatment by FTY720 (Abstract), The 6th Annual Scientific Meeting, Centre for the Study of Liver Disease, The University of Hong Kong, Hong Kong, 8 January 2005. |
| Lee K.W., Man K., Ho J.W.Y., Wang X., Poon R.T.P., Sun K.W., Ng T.P., Ng I.O.L., Xu R. and Fan S.T., Significance of the Rac signaling pathway in HCC cell motility: implications for a new therapeutic target, Carcinogenesis. 2005, 26(3): 681-687. |
| Man K., Lee K.W., Liang T.B., Lo C.M., Fung P.C.W., Tsui H.T., Li X.L., Ng T.P. and Fan S.T., FK409 ameliorates small-for-size liver graft injury by attenuation of portal hypertension and down-regulation of Egr-1 pathway, Annals of Surgery. 2004, 240(1): 159-168. |
| Man K., Ng T.P., Lee K.W., Lo C.M., Sun K.W., Li X., Zhao Y., Ho J.W.Y. and Fan S.T., FTY720 attenuates hepatic ischemia-reperfusion injury in normal and cirrhotic livers, American Journal of Transplantation. 2005, 5(1): 40-49. |
| Man K., Ng T.P., Lo C.M., Sun K.W., Zhao Y., Ho J.W.Y., Lee K.W. and Fan S.T., Hepatic I/R injury on small liver remnant promotes liver tumor growth and metastasis - activation of cell invasion and migration pathways (Abstract), The 20th International Congress of the Transplantation Society, Vienna, Austria, 5-10 September 2004. |
| Pang R.W.C., Lee K.W., Man K., Poon R.T.P., Fan S.T., Kwong Y.L. and Tse E.W.C., RNAi-mediated silencing of PIN1 inhibits HCC tumorigenicity (Abstract), The 96th Annual Meeting of the American Association for Cancer Research, Anaheim, California, U.S.A., 16-20 April 2005. |
| Pang W.C., Lee K.W., Man K., Poon R.T.P., Fan S.T., Kwong Y.L. and Tse E.W.C., Inhibition of hepatocellular carcinoma tumourigenicity by RNAi-mediated PIN1 silencing (Abstract), The 6th Annual Scientific Meeting, Centre for the Study of Liver Disease, The University of Hong Kong, Hong Kong, 8 January 2005. |
| Pang W.C., Lee K.W., Man K., Poon R.T.P., Fan S.T., Kwong Y.L. and Tse E.W.C., RNAi-mediated PIN1 silencing inhibits HCC trumourigenicity (Abstract), Asian Journal of Surgery. 2005, 28(Suppl 2): S84. |
| Pang W.C., Lee K.W., Man K., Poon R.T.P., Fan S.T., Kwong Y.L. and Tse E.W.C., RNAi-mediated PIN1 silencing inhibits HCC tumourigenicity (Abstract), The 4th International Meeting on Hepatocellular Carcinoma: Eastern and Western Experiences, Hong Kong, 14-16 December 2004. |
| Pang W.C., Lee K.W., Man K., Poon R.T.P., Fan S.T., Kwong Y.L. and Tse E.W.C., RNAi-mediated silencing of PIN1 inhibits HCC tumorigenicity, The 11th Hong Kong International Cancer Congress, Hong Kong, 10-12 November, 2004. |
| Zhao Y., Man K., Lo C.M., Ng T.P., Li X.L., Sun K.W., Lee K.W., Dai X.W. and Fan S.T., Attenuation of small-for-size liver graft injury by FTY720: significance of cell-survival Akt signaling pathway, American Journal of Transplantation. 2004, 4(9): 1399-1407. |
| Researcher : Lee KY |
| List of Research Outputs |
| Lee K.Y., The Ret gene in the enteric nervous system: expression analysis and generation of Ret deficient mice, Thesis, Doctor of Philosophy, The University of Hong Kong. 2005. |
| Researcher : Lee PY |
| Project Title: | Tight-junction claudin-19 in kidney development and renal disease |
| Investigator(s): | Lee PY, Luk JMC, Tam PC |
| Department: | Surgery |
| Source(s) of Funding: | Small Project Funding |
| Start Date: | 11/2004 |
| Abstract: |
| To isolate, identify and characterize a novel tight-junction molecule, claudin 19, which was initially found highly expressed in kidney. |
| List of Research Outputs |
| Researcher : Leon YY |
| List of Research Outputs |
| Garcia-Barcelo M.M., Ganster R.W., Lui V.C.H., Leon Y.Y., So M.T., Lau A.M.F., Fu M., Sham M.H., Knight J., Zannini M.S., Sham P.C. and Tam P.K.H., TTF-1 and RET promoter SNPs: regulation of RET transcription in Hirschsprung's disease, Human Molecular Genetics. 2005, 14(2): 191-204. |
| Researcher : Leung KL |
| List of Research Outputs |
| Cheung S.T., Leung K.L., Ip Y.C., Chen X., Fong D.Y.T., Ng I.O.L., Fan S.T. and So S., Claudin-10 expression level is associated with recurrence of primary hepatocellular carcinoma, Clinical Cancer Research. 2005, 11(2 Pt 1): 551-556. |
| Cheung S.T., Leung K.L., Kwok H.H., Wong S.Y. and Fan S.T., DNALI1 expression and gene polymorphism are associated with disease recurrence after curative surgery in hepatocellular carcinoma (Abstract), The 96th Annual Meeting of the American Association for Cancer Research, Anaheim, California, U.S.A., 16-20 April 2005. |
| Cheung S.T., Wong S.Y., Leung K.L., Chen X., So S., Ng I.O.L. and Fan S.T., Granulin-epithelin precursor (GEP) promotes growth and invasion of hepatocellular carcinoma (Abstract), The 6th Annual Scientific Meeting, Centre for the Study of Liver Disease, The University of Hong Kong, Hong Kong, 8 January 2005. |
| Cheung S.T., Wong S.Y., Leung K.L., Chen X., So S., Ng I.O.L. and Fan S.T., Granulin-epithelin precursor overexpression promotes growth and invasion in hepatocellular carcinoma, Clinical Cancer Research. 2004, 10(22): 7629-7636. |
| Cheung S.T., Ho J.C.Y., Leung K.L., Chen X., Fong D.Y.T., So S. and Fan S.T., Transcript AA454543 is a novel prognostic marker for hepatocellular carcinoma after curative partial hepatectomy, Neoplasia. 2005, 7(2): 91-98. |
| Ho J.C.Y., Cheung S.T., Leung K.L., Ng I.O.L. and Fan S.T., Decreased expression of cytochrome P450 2E1 is associated with poor prognosis of hepatocellular carcinoma, International Journal of Cancer. 2004, 111(4): 494-500. |
| Researcher : Leung PL |
| List of Research Outputs |
| Wang X., Luk J.M.C., Leung P.L., Wong W.Y., Stanbridge E.J. and Fan S.T., Alternative mRNA splicing of liver intestine-cadherin in hepatocellular carcinoma, Clinical Cancer Research. 2005, 11(2 Pt 1): 483-489. |
| Wang X., Luk J.M.C., Leung P.L., Ho D.W.Y. and Fan S.T., Overexpressing LI-cadherin genetic polymorphisms (651C/T, IVS6+35A/G) is associated with susceptibility to HCC (Abstract), The 4th International Meeting on Hepatocellular Carcinoma: Eastern and Western Experiences, Hong Kong, 14-16 December 2004. |
| Wang X., Luk J.M.C., Leung P.L., Ho D.W.Y. and Fan S.T., Overexpression LI-cadherin genetic polymorphisms (651C/T, IVS6+35A/G) is associated with susceptibility to HCC (Abstract), Asian Journal of Surgery. 2005, 28(Suppl 2): S107. |
| Wang X., Luk J.M.C., Leung P.L. and Fan S.T., Overexpression of LI-cadherin genetic polymorphisms (651C/T, IVS6+35A/G) is associated with susceptibility to hepatocellular carcinoma (Abstract), The 6th Annual Scientific Meeting, Centre for the Study of Liver Disease, The University of Hong Kong, Hong Kong, 8 January 2005. |
| Researcher : Leung SYL |
| List of Research Outputs |
| Cheung M.C., Lee F.C.W., Chu S.S.M., Leung S.Y.L., Wong B.B.W., Ho K.L. and Tam P.C., Laparoscopic nephrectomy: an early experience at Queen Mary Hospital, Hong Kong Medical Journal. 2005, 11(1): 7-11. |
| Ho K.L., Wong B.B.W., Leung S.Y.L. and Tam P.C., Clinico-pathological correlations of incidental and symptomatic renal cell carcinoma (RCC), International Journal of Urology. 2004, 11(Suppl): A7. |
| Ho K.L., Tsu H.L., Wong B.B.W., Leung S.Y.L. and Tam P.C., Oncological outcomes of upper urinary tract transitional cell carcinoma (TCC), International Journal of Urology. 2004, 11(Suppl): A8. |
| Leung S.Y.L., Wong B.B.W., Cheung M.C., Lee F.C.W. and Tam P.C., A phase II trial of continuous, oral low-dose estramustine and etoposide chemotherapy in the treatment of symptomatic hormone-refractory prostate cancer (HRCP), International Journal of Urology. 2004, 11(Suppl): A16. |
| Leung S.Y.L., Wong B.B.W., Cheung M.C., Lee F.C.W. and Tam P.C., Day case transurethral resection - vaporization of the prostate (TURVP) for the treatment of benign prostatic hyperplasia - a prospective trial, International Journal of Urology. 2004, 11(Suppl): A13. |
| Leung S.Y.L., Chan A.C.Y., Wong B.B.W., Cheung M.C., Lee F.C.W. and Tam P.C., Management of febrile urinary tract infections (UTI) complicating transrectal ultrasound guided biopsy of the prostate (TRUSBx), International Journal of Urology. 2004, 11(Suppl): A19. |
| Leung S.Y.L., Wong B.B.W., Ho K.L., Cheung M.C., Lee F.C.W. and Tam P.C., Prospective double-blind randomized controlled trial on intrarectal administration of lidocaine gel vs. plain lubricant gel for pain control during transrectal ultrasound guided extensive 10-core prostate biopsy, International Journal of Urology. 2004, 11(Suppl): A9. |
| Leung S.Y.L., Cheung M.C., Wong B.B.W., Lee F.C.W. and Tam P.C., Transurethral ethanol ablation of the prostate (TEAP) for the management of acute retention of urine in patients with compromised medical risks, International Journal of Urology. 2004, 11(Suppl): A48-A49. |
| Tam P.C., Leung S.Y.L. and Wong B.B.W., Radical cystectomy; refining the techniques, BIU International. 2004, 94(Suppl2): 109-110. |
| Wong B.B.W., Cheung M.C., Leung S.Y.L., Lee F.C.W. and Tam P.C., A prospective, randomized study comparing transurethral resection of prostate (TURP) with transurethral resection - vaporization of prostate (TURVP) on treatment for acute urinary retention, International Journal of Urology. 2004, 11(Suppl): A11-A12. |
| Researcher : Li AZ |
| List of Research Outputs |
| Ho K.M.T., Li A.Z., Yiu M.K., Lee K.C., Lui V.C.H., Fung P.C.W., Yiu T.F. and Tam P.K.H., Altered expression of aquaporin-2 in human explants with chronic renal allograft dysfunction, BJU International. 2005, 95: 1104-1108. |
| Researcher : Li Q |
| List of Research Outputs |
| Liu Y., Poon R.T.P., Li Q., Kok T.W., Lau C.P.Y. and Fan S.T., Both antiangiogenesis- and angiogenesis-independent effects are responsible for hepatocellular carcinoma growth arrest by tyrosine kinase inhibitor PTK787/ZK222584, Cancer Research. 2005, 65(9): 3691-3699. |
| Researcher : Li W |
| List of Research Outputs |
| Ren Y., Chen Y., Li W., Jiang G., Liu Q., Chan H.M. and Tam P.K.H., Anti-sense gene therapy for human neuroblastoma by targeting disruption of macrophage migration inhibitory factor (MIF): in vitro and nude mice studies, 51st Annual International Congress of British Association of Paediatric Surgeons, Oxford, U.K. 27-30 July 2004. |
| Ren Y., Li W., Liu Q., Yu W.Y., Sun R.W.Y., Che C.M. and Tam P.K.H., Gold (III) porphyrines: a novel chemotherapeutic agent for human neuroblastoma, 51st Annual International Congress of British Association of Paediatric Surgeons, Oxford, U.K. 27-30 July. 2004. |
| Researcher : Li X |
| List of Research Outputs |
| Li X., Tian L., Lamb J.R. and Tam P.K.H., Anti-TGF-beta prevents chronic rejection in a rat orthotopic small bowel transplantation model, IXth International Small Bowel Transplantation Symposium, Brussels, Belgium, 30 June - 2 July 2005. |
| Man K., Ng T.P., Lee K.W., Lo C.M., Sun K.W., Li X., Zhao Y., Ho J.W.Y. and Fan S.T., FTY720 attenuates hepatic ischemia-reperfusion injury in normal and cirrhotic livers, American Journal of Transplantation. 2005, 5(1): 40-49. |
| Tam P.K.H., Tian L., Li X. and Lamb J.R., Inhibition of sonic hedgehog signaling reduces chronic allograft rejection in rat small bowel transplantation, IXth International Small Bowel Transplantation Symposium, Brussels, Belgium, 30 June - 2 July 2005. |
| Tam P.K.H., Tian L., Li X., Dallman M. and Lamb J.R., Inhibition of sonic hedgehog singaling reduces chronic allograft rejection in rat small bowel transplantation, 9th Basic Science Symposium of the Transplantation Society, LaBaule, France, 19-22 June 2005. |
| Researcher : Li X |
| List of Research Outputs |
| Li X., Tian L., Lamb J.R. and Tam P.K.H., Anti-TGF-beta prevents chronic rejection in a rat orthotopic small bowel transplantation model, IXth International Small Bowel Transplantation Symposium, Brussels, Belgium, 30 June - 2 July 2005. |
| Man K., Ng T.P., Lee K.W., Lo C.M., Sun K.W., Li X., Zhao Y., Ho J.W.Y. and Fan S.T., FTY720 attenuates hepatic ischemia-reperfusion injury in normal and cirrhotic livers, American Journal of Transplantation. 2005, 5(1): 40-49. |
| Tam P.K.H., Tian L., Li X. and Lamb J.R., Inhibition of sonic hedgehog signaling reduces chronic allograft rejection in rat small bowel transplantation, IXth International Small Bowel Transplantation Symposium, Brussels, Belgium, 30 June - 2 July 2005. |
| Tam P.K.H., Tian L., Li X., Dallman M. and Lamb J.R., Inhibition of sonic hedgehog singaling reduces chronic allograft rejection in rat small bowel transplantation, 9th Basic Science Symposium of the Transplantation Society, LaBaule, France, 19-22 June 2005. |
| Researcher : Li X |
| List of Research Outputs |
| Li X., Tian L., Lamb J.R. and Tam P.K.H., Anti-TGF-beta prevents chronic rejection in a rat orthotopic small bowel transplantation model, IXth International Small Bowel Transplantation Symposium, Brussels, Belgium, 30 June - 2 July 2005. |
| Man K., Ng T.P., Lee K.W., Lo C.M., Sun K.W., Li X., Zhao Y., Ho J.W.Y. and Fan S.T., FTY720 attenuates hepatic ischemia-reperfusion injury in normal and cirrhotic livers, American Journal of Transplantation. 2005, 5(1): 40-49. |
| Tam P.K.H., Tian L., Li X. and Lamb J.R., Inhibition of sonic hedgehog signaling reduces chronic allograft rejection in rat small bowel transplantation, IXth International Small Bowel Transplantation Symposium, Brussels, Belgium, 30 June - 2 July 2005. |
| Tam P.K.H., Tian L., Li X., Dallman M. and Lamb J.R., Inhibition of sonic hedgehog singaling reduces chronic allograft rejection in rat small bowel transplantation, 9th Basic Science Symposium of the Transplantation Society, LaBaule, France, 19-22 June 2005. |
| Researcher : Li Z |
| List of Research Outputs |
| Ren Y., Lin C.L., Li Z., Chen X.Y., Huang X., Lui V.C.H., Nicholls J.M., Lan H.Y. and Tam P.K.H., Up-regulation of macrophage migration inhibitory factor in infants with acute neonatal necrotizing enterocolitis, Histopathology. 2005, 46(6): 659-667. |
| Yi C., Li Z., Yuan K., Qu X., Chen J., Wang G., Zhang H., Luo H., Zhu L., Jiang P., Chen L., Shen Y., Luo M., Zuo G., Hu J., Duan D., Nie Y., Shi X., Wang W., Han Y., Li T., Liu Y., Ding M., Deng H. and Xu X., Small molecules blocking the entry of SARS-Co V into host, Journal of Virology. 2004, 78(2)): 11334-11339. |
| Researcher : Li ZLA |
| List of Research Outputs |
| Li Z.L.A., Aquaporins in kidney development and disease, Thesis, Master of Philosophy, The University of Hong Kong. 2004. |
| Researcher : Lin C |
| Project Title: | Discovery and clinical evaluation of novel immunogenic peptides for immunotherapy of nasopharyngeal carcinoma |
| Investigator(s): | Lin CL, Yu WY |
| Department: | Surgery |
| Source(s) of Funding: | Innovation and Technology Support Programme |
| Start Date: | 06/2002 |
| Abstract: |
| To prepare MAP/polyepitope of the LMP1/LMP2 native peptides; to identify highly immunogenic MAPs of the LMP1/LMP2 native peptides by in vitro immunoassays and in reactivating the CTL lines from asymptomatic carriers or NPC patients; to prepare LMP1/LMP2 templated peptide libraries; to identify highly immunogenic peptides from the synthetic peptide libraries by in vitro immunoassays and in reactivating the CTL lines from asymptomatic carriers or NPC patients; to prepare MAP/polyepitope of the synthetic peptide(s) for amplification of immunogenecity; to identify novel peptide candidates for clinical studies; to formulate studies of immunogenic peptides and MAPs; to pulse the dendritic cells from NPC patents with the lead peptides/MAP, followed by intradonal injection into the patients; to evaluate tumor growth in patients with local recurrence or metastasis. |
| Project Title: | The role of DC-SIGN in the regulation of dendritic cell function and T cell responses: from HIV immunopathology to the induction of peripheral T cell tolerance |
| Investigator(s): | Lin CL, Xu S.N., Austyn J.M. |
| Department: | Surgery |
| Source(s) of Funding: | Competitive Earmarked Research Grants (CERG) |
| Start Date: | 11/2002 |
| Abstract: |
| The project attempts to characterize the role of DC-DIGN in the regulation of dendritic cell function, and to evaluate the inhibitory effect of DC-SIGN-modulated DC on T cell responses to primary and recall antigens in vitro and in vivo. This study will provide critical insights into the molecular mechanisms whereby DC-SIGN contributes to immunosuppression or peripheral tolerance, which may allow us to design more effective strategies for antiviral therapies and the induction of transplantation tolerance. |
| Project Title: | Development of heat shock protein-based cancer vaccine against hepatitis B virus-induced hepatocellular carcinoma |
| Investigator(s): | Lin CL, Tam PKH, Fan ST, Yu WY, Chen Y |
| Department: | Surgery |
| Source(s) of Funding: | Seed Funding Programme for Applied Research |
| Start Date: | 06/2003 |
| Abstract: |
| To examine the effect of heat shock protein (hsp) gp96 with hepatitis B virus (HBV)-specific antigen YVNTNMG (YVN) in the induction of peptide-specific cytotoxic T cell immunity in vivo; to conduct a dendritic cell-based immunotherapy trial on patients with unresectable HBV-related hepatocellular carcinoma (HCC); to search and discover novel peptide analogues to enhance the antigenecity of hsp-peptide complex through creation of combinatorial peptide library and phage display method. |
| Project Title: | The effect of SARS-associated coronavirus Spike protein on immune regulation of SARS |
| Investigator(s): | Lin CL, Chan VSF |
| Department: | Surgery |
| Source(s) of Funding: | VCO SARS Research Fund |
| Start Date: | 07/2003 |
| Abstract: |
| To delineate the immune regulatory mechanisms in the afferent and efferent phases of immune responses against SARS-CoV (Severe Acute Respiratory Syndrome Coronavirus) infection. |
| Project Title: | Development of DNA and viral vector vaccines against Epstein-Barr virus-positive nasopharyngeal carcinoma |
| Investigator(s): | Lin CL, Xu X.N., Austyn J.M. |
| Department: | Surgery |
| Source(s) of Funding: | Merit Award for RGC CERG Funded Projects |
| Start Date: | 09/2003 |
| Abstract: |
| To design and parpare DNA vaccine encoding EBNA1 and LMP2, and the MVA vaccine encoding the cytokine GM-CSF, the chemokine RANTES, the EBV- specific lytic antigen EBNA-1, and EBV-specific latent antigen LMP2; to identify the efficacy of these vaccines in vitro on their capacity in attracting dendritic cells and also in the induction of EBNA-1 specific CD4+T cell response and LMP2-specific CTL immunity; to verify the efficacy of these vaccines in a mouse NPC and a B cell lymphoma model, including the potency of CD4+ and CTL immunity, and also to test the effect of the dosage, route, and the effect of combinational use of both the DNA and MVA vaccines. |
| Project Title: | Development of DNA and viral vector vaccines against Epstein-Barr virus-positive nasopharyngeal carcinoma |
| Investigator(s): | Lin CL, Xu X.N., Austyn J.M. |
| Department: | Surgery |
| Source(s) of Funding: | Competitive Earmarked Research Grants (CERG) |
| Start Date: | 09/2003 |
| Abstract: |
| To design and parpare DNA vaccine encoding EBNA1 and LMP2, and the MVA vaccine encoding the cytokine GM-CSF, the chemokine RANTES, the EBV- specific lytic antigen EBNA-1, and EBV-specific latent antigen LMP2; to identify the efficacy of these vaccines in vitro on their capacity in attracting dendritic cells and also in the induction of EBNA-1 specific CD4+T cell response and LMP2-specific CTL immunity; to verify the efficacy of these vaccines in a mouse NPC and a B cell lymphoma model, including the potency of CD4+ and CTL immunity, and also to test the effect of the dosage, route, and the effect of combinational use of both the DNA and MVA vaccines. |
| Project Title: | Development and clinical evaluation of peptide vaccines for immunotherapy of Epstein-Barr virus-positive nasopharyngeal carcinoma |
| Investigator(s): | Lin CL, Wang XN, Tam PKH, Che CM, Guo Z.H., Zeng YX, Meng MG |
| Department: | Surgery |
| Source(s) of Funding: | NSFC/RGC Joint Research Scheme |
| Start Date: | 12/2004 |
| Abstract: |
| To design and prepare peptide vaccines composed of novel peptide analogues of the Epstein-Barr virus (EBV)-specific antigen latent membrane protein 2 (LMP2), EBV-specific nuclear antigen type 1 (EBNA1), the DC-specific monocyte-derived chemokine (MDC), and the dendritic cell (DC) activator CD40 ligand; to assess the efficacy of this peptide vaccine in vitro and in vivo in a NOD/SCID mouse model in terms of the capacity in attracting DCs and inducing LMP2- and EBNA1-specific T cell immunity; to conduct a phase I clinical trial to verify in vivo the efficacy of peptide vaccine in human subjects, including the safety and toxicity, the EBV-specific CD4 and CD8 T cell responsiveness, and the effect of the dosage and regimen in boosting and maintaining the longevity of effective T cell immunity. |
| List of Research Outputs |
| Researcher : Lin CL |
| Project Title: | Discovery and clinical evaluation of novel immunogenic peptides for immunotherapy of nasopharyngeal carcinoma |
| Investigator(s): | Lin CL, Yu WY |
| Department: | Surgery |
| Source(s) of Funding: | Innovation and Technology Support Programme |
| Start Date: | 06/2002 |
| Abstract: |
| To prepare MAP/polyepitope of the LMP1/LMP2 native peptides; to identify highly immunogenic MAPs of the LMP1/LMP2 native peptides by in vitro immunoassays and in reactivating the CTL lines from asymptomatic carriers or NPC patients; to prepare LMP1/LMP2 templated peptide libraries; to identify highly immunogenic peptides from the synthetic peptide libraries by in vitro immunoassays and in reactivating the CTL lines from asymptomatic carriers or NPC patients; to prepare MAP/polyepitope of the synthetic peptide(s) for amplification of immunogenecity; to identify novel peptide candidates for clinical studies; to formulate studies of immunogenic peptides and MAPs; to pulse the dendritic cells from NPC patents with the lead peptides/MAP, followed by intradonal injection into the patients; to evaluate tumor growth in patients with local recurrence or metastasis. |
| Project Title: | The role of DC-SIGN in the regulation of dendritic cell function and T cell responses: from HIV immunopathology to the induction of peripheral T cell tolerance |
| Investigator(s): | Lin CL, Xu S.N., Austyn J.M. |
| Department: | Surgery |
| Source(s) of Funding: | Competitive Earmarked Research Grants (CERG) |
| Start Date: | 11/2002 |
| Abstract: |
| The project attempts to characterize the role of DC-DIGN in the regulation of dendritic cell function, and to evaluate the inhibitory effect of DC-SIGN-modulated DC on T cell responses to primary and recall antigens in vitro and in vivo. This study will provide critical insights into the molecular mechanisms whereby DC-SIGN contributes to immunosuppression or peripheral tolerance, which may allow us to design more effective strategies for antiviral therapies and the induction of transplantation tolerance. |
| Project Title: | Development of heat shock protein-based cancer vaccine against hepatitis B virus-induced hepatocellular carcinoma |
| Investigator(s): | Lin CL, Tam PKH, Fan ST, Yu WY, Chen Y |
| Department: | Surgery |
| Source(s) of Funding: | Seed Funding Programme for Applied Research |
| Start Date: | 06/2003 |
| Abstract: |
| To examine the effect of heat shock protein (hsp) gp96 with hepatitis B virus (HBV)-specific antigen YVNTNMG (YVN) in the induction of peptide-specific cytotoxic T cell immunity in vivo; to conduct a dendritic cell-based immunotherapy trial on patients with unresectable HBV-related hepatocellular carcinoma (HCC); to search and discover novel peptide analogues to enhance the antigenecity of hsp-peptide complex through creation of combinatorial peptide library and phage display method. |
| Project Title: | The effect of SARS-associated coronavirus Spike protein on immune regulation of SARS |
| Investigator(s): | Lin CL, Chan VSF |
| Department: | Surgery |
| Source(s) of Funding: | VCO SARS Research Fund |
| Start Date: | 07/2003 |
| Abstract: |
| To delineate the immune regulatory mechanisms in the afferent and efferent phases of immune responses against SARS-CoV (Severe Acute Respiratory Syndrome Coronavirus) infection. |
| Project Title: | Development of DNA and viral vector vaccines against Epstein-Barr virus-positive nasopharyngeal carcinoma |
| Investigator(s): | Lin CL, Xu X.N., Austyn J.M. |
| Department: | Surgery |
| Source(s) of Funding: | Merit Award for RGC CERG Funded Projects |
| Start Date: | 09/2003 |
| Abstract: |
| To design and parpare DNA vaccine encoding EBNA1 and LMP2, and the MVA vaccine encoding the cytokine GM-CSF, the chemokine RANTES, the EBV- specific lytic antigen EBNA-1, and EBV-specific latent antigen LMP2; to identify the efficacy of these vaccines in vitro on their capacity in attracting dendritic cells and also in the induction of EBNA-1 specific CD4+T cell response and LMP2-specific CTL immunity; to verify the efficacy of these vaccines in a mouse NPC and a B cell lymphoma model, including the potency of CD4+ and CTL immunity, and also to test the effect of the dosage, route, and the effect of combinational use of both the DNA and MVA vaccines. |
| Project Title: | Development of DNA and viral vector vaccines against Epstein-Barr virus-positive nasopharyngeal carcinoma |
| Investigator(s): | Lin CL, Xu X.N., Austyn J.M. |
| Department: | Surgery |
| Source(s) of Funding: | Competitive Earmarked Research Grants (CERG) |
| Start Date: | 09/2003 |
| Abstract: |
| To design and parpare DNA vaccine encoding EBNA1 and LMP2, and the MVA vaccine encoding the cytokine GM-CSF, the chemokine RANTES, the EBV- specific lytic antigen EBNA-1, and EBV-specific latent antigen LMP2; to identify the efficacy of these vaccines in vitro on their capacity in attracting dendritic cells and also in the induction of EBNA-1 specific CD4+T cell response and LMP2-specific CTL immunity; to verify the efficacy of these vaccines in a mouse NPC and a B cell lymphoma model, including the potency of CD4+ and CTL immunity, and also to test the effect of the dosage, route, and the effect of combinational use of both the DNA and MVA vaccines. |
| Project Title: | Development and clinical evaluation of peptide vaccines for immunotherapy of Epstein-Barr virus-positive nasopharyngeal carcinoma |
| Investigator(s): | Lin CL, Wang XN, Tam PKH, Che CM, Guo Z.H., Zeng YX, Meng MG |
| Department: | Surgery |
| Source(s) of Funding: | NSFC/RGC Joint Research Scheme |
| Start Date: | 12/2004 |
| Abstract: |
| To design and prepare peptide vaccines composed of novel peptide analogues of the Epstein-Barr virus (EBV)-specific antigen latent membrane protein 2 (LMP2), EBV-specific nuclear antigen type 1 (EBNA1), the DC-specific monocyte-derived chemokine (MDC), and the dendritic cell (DC) activator CD40 ligand; to assess the efficacy of this peptide vaccine in vitro and in vivo in a NOD/SCID mouse model in terms of the capacity in attracting DCs and inducing LMP2- and EBNA1-specific T cell immunity; to conduct a phase I clinical trial to verify in vivo the efficacy of peptide vaccine in human subjects, including the safety and toxicity, the EBV-specific CD4 and CD8 T cell responsiveness, and the effect of the dosage and regimen in boosting and maintaining the longevity of effective T cell immunity. |
| List of Research Outputs |
| Lan L.C.L., Lin C.L. and Tam P.K.H., Central venous catheterization in children for parenteral nutrition delivery carry a higher risk for infection - experience in a tertiary referring hospital, 19th Congress of the Asian Association of Paediatric Surgeons, Hong Kong, 28 November - 1 December 2004. |
| Lan L.C.L., Lin C.L., Wong K.K.Y. and Tam P.K.H., Parenteral nutrition is a major risk factor for children undergoing central venous catheterization, 38th Annual Meeting of the Pacific Association of Pediatric Surgery, Vancouver, Canada, 22-26 May 2005. |
| Lan L.C.L., Lee K.K., Lin C.L., Wong K.K.Y. and Tam P.K.H., Placement of percutaneous endoscopic gastrostomy in children with ventriculoperitoneal shunt, 38th Annual Meeting of the Pacific Association of Pediatric Surgery, Vancouver, Canada, 22-26 May 2005. |
| Lin C.L., Fan S.T., Lo C.M. and Wong J., The role of endoscopic ultrasonography in the management of acute pancreatitis: a prospective randomized study (Invited Lecture), The 12th United European Gastroenterology Week, Prague, Czech Republic, 25-29 September 2004. |
| Ren Y., Lin C.L., Li Z., Chen X.Y., Huang X., Lui V.C.H., Nicholls J.M., Lan H.Y. and Tam P.K.H., Up-regulation of macrophage migration inhibitory factor in infants with acute neonatal necrotizing enterocolitis, Histopathology. 2005, 46(6): 659-667. |
| Wong K.K.Y., Fan A.H., Lan L.C.L., Lin C.L. and Tam P.K.H., Effective antibiotic regime for postoperative acute cholangitis in biliary atresia - an evolving scene, Journal of Pediatric Surgery. 2004, 39(12): 1800-1802. |
| Wong K.K.Y., Lan L.C.L., Lin C.L., Chan A.W.S. and Tam P.K.H., Mucous fistula refeeding in premature neonates with enterostomies, Journal of Pediatric Gastroenterology and Nutrition. 2004, 39: 43-45. |
| Wong K.K.Y., Khong P.L., Lin C.L., Lam W.W.M., Lan L.C.L. and Tam P.K.H., Post-operative magnetic resonance evaluation of children after laparoscopic anorectoplasty for imperforate anus, International Journal of Colorectal Disease. 2005, 20(1): 33-37. |
| Wong K.K.Y., Lan L.C.L., Lin C.L. and Tam P.K.H., Superior mesenteric artery syndrome: are we over-diagnosing in children?, 19th Congress of the Asian Association of Paediatric Surgeons, Hong Kong, 28 November - 1 December 2004. |
| Wong K.K.Y., Lan L.C.L., Lin C.L. and Tam P.K.H., The electronic surgical unit: a stride into the 21st century, 19th Congress of the Asian Association of Paediatric Surgeons, Hong Kong, 28 November - 1 December 2004. |
| Wong K.K.Y., Lan L.C.L., Lin C.L. and Tam P.K.H., The use of positron emission tomography in detecting hepatoblastoma recurrence - a cautionary tale, Journal of Pediatric Surgery. 2004, 39(12): 1779-1781. |
| Wong K.K.Y., Chung P.H.Y., Lan L.C.L., Lin C.L. and Tam P.K.H., Trends in the prevalence of H. pylori in symptomatic children in the era of eradication, 38th Annual Meeting of the Pacific Association of Pediatric Surgery, Vancouver, Canada, 22-26 May 2005. |
| Researcher : Liu CL |
| Project Title: | Health-related quality of life of donors in live donor liver transplantation |
| Investigator(s): | Liu CL, Fan ST |
| Department: | Surgery |
| Source(s) of Funding: | Small Project Funding |
| Start Date: | 11/2002 |
| Abstract: |
| To determine the HRQL of donors in LDLT. From a utilitarian point of view, these data could be incorporated into the process of balancing the risks and benefits of LDLT; to identify factors which are predictors of good quality of life of donors. |
| Project Title: | The significance of intra-graft expression profile and ultrastructural features at early phase after liver transplantation-a prospective study of liver transplantation using cadaver and live donors |
| Investigator(s): | Liu CL, Man K |
| Department: | Surgery |
| Source(s) of Funding: | Small Project Funding |
| Start Date: | 11/2003 |
| Abstract: |
| To investigate the gene expression profiles of the donor and graft at the early phase after liver transplantation associated with hepatic ultrastructural features in liver transplantation using cadaver and live donors; to study the correlation of graft status, gene expression patterns with early and late clinical outcome functionally and morphologically. |
| Project Title: | Portal vein embolization before major right hepatic resection for hepatocellular carcinoma: a prospective randomized study |
| Investigator(s): | Liu CL |
| Department: | Surgery |
| Source(s) of Funding: | Incentive Award for RGC CERG Fundable But Not Funded Projects |
| Start Date: | 07/2004 |
| Abstract: |
| Refer to hard copy |
| List of Research Outputs |
| Au W.Y. and Liu C.L., Growth of giant hepatic hemangioma after triplet pregnancy , Hepatology. 2005, 42(5): 781. |
| Au W.Y., Liu C.L., Lo C.M., Fan S.T. and Ma E.S.K., Potential role for platelet apheresis for post-liver transplant thrombocytosis complicating portal vein thrombosis, Journal of Clinical Apheresis. 2004, 19(4): 192-196. |
| Chan S.C., Liu C.L., Lo C.M. and Fan S.T., Applicability of histidine-tryptophan-ketoglutarate solution in right lobe adult-to-adult live donor liver transplantation, Liver Transplantation. 2004, 10(11): 1415-1421. |
| Chan S.C., Liu C.L., Lo C.M. and Fan S.T., Primacy of hepatovascular flowmetry in right lobe adult-to-adult live donor liver transplantation (Abstract), The 6th Annual Scientific Meeting, Centre for the Study of Liver Disease, The University of Hong Kong, Hong Kong, 8 January 2005. |
| Chan S.C., Liu C.L., Lo C.M. and Fan S.T., Rapid onset Chilaiditi's sign on top of fulminant hepatic failure (Case Report), Hepatobiliary and Pancreatic Diseases International. 2004, 3(3): 476-477. |
| Chan S.C., Lo C.M., Liu C.L. and Fan S.T., Resurgence of biliary cast syndrome (Images in Liver Transplantation), Liver Transplantation. 2005, 11(2): 242-243. |
| Chan S.Y., Poon R.T.P., Ng K.K.C., Liu C.L., Chan R.T. and Fan S.T., Long-term survival after intraluminal brachytherapy for inoperable hilar cholangiocarcinoma: a case report (Case Report), World Journal of Gastroenterology. 2005, 11(20): 3161-3164. |
| Chiu A., Tam S., Au W.Y., Chan S.C., Liu C.L. and Fan S.T., MARS treatment for a patient presenting with acquired hepatic glutamine synthetase deficiency after orthotopic liver transplantation (Case Report), Liver Transplantation. 2005, 11(3): 353-355. |
| Liu C.L., Abdominal drainage in liver surgery (Invited Lecture), Beijing-Hong Kong Joint Forum on General Surgery, Beijing, China, 12 July 2004. 2004. |
| Liu C.L., Advances in living donor liver transplantation (Invited Lecture), Stanford University - The University of Hong Kong Transplantation Symposium, Hong Kong, China, 22 January 2005. 2005. |
| Liu C.L., Anterior approach hepatic resection for hepatocellular carcinoma (Invited Lecture), The 4th International Meeting on Hepatocellular Carcinoma: Eastern and Western Experiences, Hong Kong, 14-16 December 2004. |
| Liu C.L., Chairman of Local Organizing Committee, The 4th International Meeting on Hepatocellular Carcinoma: Eastern and Western Experiences, Hong Kong, 14-16 December 2004. 2004. |
| Liu C.L., Fan S.T., Lo C.M. and Wong J., Clinicobiochemical prediction of biliary cause for acute pancreatitis in the era of endoscopic ultrasonography (Poster Presentation), The 12th United European Gastroenterology Week, Prague, Czech Republic, 25-29 September 2004. |
| Liu C.L., Hepatic resection for hepatocellular carcinoma (Invited Lecture), Visiting Fellow (Li Koon Chun Surgical Travelling Fellowship) to Department of General, Visceral and Transplantation Surgery, Charite-Campus Virchow Klinikum, Humboldt University Berlin, Berlin, Germany, 19-24 July 2004. 2004. |
| Liu C.L., Hepatic resection for hepatocellular carcinoma: the Queen Mary Hospital experience (Invited Lecture), Visiting Fellow (Li Koon Chun Surgical Travelling Fellowship) to Department of Surgery, Memorial Sloan-Kettering Cancer Center, New York, U.S.A., 15-19 November 2004 . 2004. |
| Liu C.L., Fan S.T., Lo C.M., Chan S.C., Tso W.K., Ng I.O.L. and Wong J., Hepatic resection for incidentaloma, Journal of Gastrointestinal Surgery. 2004, 8(7): 785-793. |
| Liu C.L., Immunology and immunotherapy, 19th Congress of the Asian Association of Paediatric Surgeons, Hong Kong, 28 November - 1 December 2004. |
| Liu C.L., Fan S.T., Lo C.M., Tso W.K. and Wong J., Improved operative and survival outcomes of surgical treatment for hilar cholangiocarcinoma (Abstract), HPB. 2005, 7(1 Suppl): 129. |
| Liu C.L., Fan S.T., Lo C.M., Tso W.K. and Wong J., Improved operative and survival outcomes of surgical treatment for hilar cholangiocarcinoma (Invited Lecture), The 6th Congress of the European Hepato-Pancreato-Biliary Association, Heidelberg, Germany, 25-28 May 2005. |
| Liu C.L., Live donor liver transplantation – The current status (Invited Lecture), Frontiers in Biomedical Research - Clinical Application, Beijing, China, 3 December 2004. |
| Liu C.L., Liver transplantation in Hong Kong (Invited Lecture), The 6th Annual Scientific Meeting, Centre for the Study of Liver Disease, The University of Hong Kong, Hong Kong, 8 January 2005. |
| Liu C.L., Member of Organizing Committee, Digestive Disease Weekend, Hong Kong, 18-19 September 2004. 2004. |
| Liu C.L., Fan S.T., Lo C.M., Wei W.I., Chan S.C., Yong B.H., Lai C.L. and Wong J., Operative outcomes of adult-to-adult right lobe live donor liver transplantation: a comparative study with cadaveric whole-graft liver transplantation in a single center (Abstract), The 20th International Congress of the Transplantation Society, Vienna, Austria, 5-10 September 2004. |
| Liu C.L., Right lobe live donor liver transplantation - the Hong Kong experience (Invited Lecture), First Nanjing - Hong Kong Living Donor Liver Transplantation Symposium, Nanjing, China, 22 April 2005. 2005. |
| Liu C.L., Fan S.T., Lo C.M., Chan S.C., Yong B.H. and Wong J., Safety of donor right hepatectomy without abdominal drainage: a prospective evaluation in 100 consecutive liver donors, Liver Transplantation. 2005, 11(3): 314-319. |
| Liu C.L., Therapeutic options for hepatocellular carcinoma (Invited Lecture), Frontiers in Biomedical Research - Clinical Application, Beijing, Hong Kong, 3 December 2004. |
| Lo C.M., Liu C.L. and Fan S.T., Correction of left hepatic vein redundancy in paediatric liver transplantation, Asian Journal of Surgery. 2005, 28(1): 55-57. |
| Lo C.M., Fan S.T., Liu C.L., Yong B.H., Wong Y., Lau G., Lai C.L., Ng I.O.L. and Wong J., Lessons learned from one hundred right lobe living donor liver transplants, Annals of Surgery. 2004, 240(1): 151-158. |
| Lo C.M., Liu C.L., Lau G., Chan S.C., Ng I.O.L., Fan S.T. and Wong J., Liver transplantation for chronic hepatitis B with lamivudine-resistant YMDD mutant using add-on adefovir dipivoxil to lamivudine (Abstract), American Journal of Transplantation. 2005, 5(Suppl): 180. |
| Lo C.M., Liu C.L., Lau G., Chan S.C., Ng I.O.L., Fan S.T. and Wong J., Liver transplantation for chronic hepatitis B with lamivudine-resistant YMDD mutant using add-on adefovir dipivoxil to lamivudine (Poster Presentation), American Transplant Congress, Seattle, U.S.A., 21-25 May 2005. |
| Lo C.M., Fan S.T., Liu C.L., Chan S.C., Ng I.O.L. and Wong J., Living donor versus deceased donor liver transplantation for early unresectable hepatocellular carcinoma: same criteria, different outcome (Abstract), HPB. 2005, 7(1 Suppl): 54. |
| Lo C.M., Fan S.T., Liu C.L., Chan S.C., Ng I.O.L. and Wong J., Living donor versus deceased donor liver transplantation for early unresectable hepatocellular carcinoma: same criteria, different outcome (Invited Lecture), The 6th Congress of the European Hepato-Pancreato-Biliary Association, Heidelberg, Germany, 25-28 May 2005. |
| Lo C.M., Fan S.T., Liu C.L., Chan S.C., Ng I.O.L. and Wong J., Living donor versus deceased donor liver transplantation for small unresectable hepatocellular carcinoma: same criteria, different outcome (Invited Lecture), The 6th Annual Scientific Meeting, Centre for the Study of Liver Disease, The University of Hong Kong, Hong Kong, 8 January 2005. |
| Ng K., Lam C.M., Liu C.L. and Fan S.T., Surgical treatment of colorectal liver metastases (Abstract), The 6th Annual Scientific Meeting, Centre for the Study of Liver Disease, The University of Hong Kong, Hong Kong, 8 January 2005. |
| Poon R.T.P., Fan S.T., Lo C.M., Liu C.L., Lam C.M., Yuen W.K., Yeung C. and Wong J., Improving perioperative outcome expands the role of hepatectomy in management of benign and malignant hepatobiliary diseases: analysis of 1222 consecutive patients from a prospective database, Annals of Surgery. 2004, 240(4): 698-708. |
| Qian Y.B., Liu C.L., Lo C.M. and Fan S.T., Risk factors for biliary complications after liver transplantation, Archives of Surgery. 2004, 139(10): 1101-1105. |
| Tian M.G., Tso W.K., Lo C.M., Liu C.L. and Fan S.T., Treatment of hepatic artery thrombosis after orthotopic liver transplantation, Asian Journal of Surgery. 2004, 27(3): 213-217. |
| Yong J.L., Lam C.M., Chan O.O., Poon R.T.P., Liu C.L., Lo C.M. and Fan S.T., Better survival in female patients with hepatocellular carcinoma (Abstract), Asian Journal of Surgery. 2005, 28(Suppl 2): S94. |
| Yong J.L., Lam C.M., Chan O.O., Poon R.T.P., Liu C.L., Lo C.M. and Fan S.T., Better survival in female patients with hepatocellular carcinoma (Abstract), The 4th International Meeting on Hepatocellular Carcinoma: Eastern and Western Experiences, Hong Kong, 14-16 December 2004. |
| Researcher : Liu Y |
| List of Research Outputs |
| Lin X., Xu X., Huang Q.L., Liu Y., Zheng D.L., Chen W.N. and Lin J.Y., Biological impacts of the "hot-spot" mutations on hepatitis B virus X proteins are genotype B and C differentiated, World Journal of Gastroenterology. 2005, 11(30): 4703-4708. |
| Liu Y., Poon R.T.P. and Fan S.T., Antitumor activity of epidermal growth factor receptor tyrosine kinase Inhibitors in human hepatocellular carcinoma cell lines (Abstract), The 44th American Society For Cell Biology Annual Meeting, Washington D.C., U.S.A., December 4-8 2004. |
| Liu Y., Poon R.T.P., Shao W. and Fan S.T., Antitumour activity of epidermal growth factor receptor tyrosine kinase inhibitors in human hepatocellular carcinoma (Abstract), Asian Journal of Surgery. 2005, 28(Suppl 2): S90. |
| Liu Y., Poon R.T.P., Shao W. and Fan S.T., Antitumour activity of epidermal growth factor receptor tyrosine kinase inhibitors in human hepatocellular carcinoma (Abstract), The 4th International Meeting on Hepatocellular Carcinoma: Eastern and Western Experiences, Hong Kong, 14-16 December 2004. |
| Liu Y., Poon R.T.P. and Fan S.T., Blockage of vascular endothelial growth factor receptors by tyrosine kinase inhibitor PTK787/ZK222584 inhibits growth of hepatocellular carcinoma with metastatic potential by angiogenesis-independent effect (Abstract), The 96th Cancer Research Annual Meeting, Anaheim, California, U.S.A., 16-20 April 2005. |
| Liu Y., Poon R.T.P., Li Q., Kok T.W., Lau C.P.Y. and Fan S.T., Both antiangiogenesis- and angiogenesis-independent effects are responsible for hepatocellular carcinoma growth arrest by tyrosine kinase inhibitor PTK787/ZK222584, Cancer Research. 2005, 65(9): 3691-3699. |
| Liu Y., Poon R.T.P., Hughes J., Feng X., Yu W.C. and Fan S.T., Chemokine receptors support infiltration of lymphocyte subpopulations in human hepatocellular carcinoma, Clinical Immunology. 2005, 114(2): 174-182. |
| Liu Y., Poon R.T.P., Hughes J., Li Q.Y., Yu W.C. and Fan S.T., Desensitization of T lymphocyte function by CXCR3 ligands in human hepatocellular carcinoma, World Journal of Gastroenterology. 2005, 11(2): 164-170. |
| Poon R.T.P., Yang Z., Liu Y., Ho D.W.Y., Lau C.K. and Fan S.T., Blockade of vascular endothelial growth factor (VEGF) receptor enhances the therapeutic efficacy and chemotherapy in hepatocellular carcinoma (Abstract), The 96th Annual Meeting of the American Association for Cancer Research, Anaheim, California, U.S.A., 16-20 April 2005. |
| Xu Y., Sun H.C., Liu Y., Poon R.T.P. and Tang Z.Y., A specific peptide to human hepatocellular carcinoma vasculature selected by modified in vitro phage display (Abstract), Asian Journal of Surgery. 2005, 28(Suppl): S91. |
| Xu Y., Sun H.C., Liu Y., Poon R.T.P. and Tang Z.Y., A specific peptide to human hepatocellular carcinoma vasculature selected by modified in vitro phage display (Abstract), The 4th International Meeting on Hepatocellular Carcinoma: Eastern and Western Experiences, Hong Kong, 14-16 December 2004. |
| Yi C., Li Z., Yuan K., Qu X., Chen J., Wang G., Zhang H., Luo H., Zhu L., Jiang P., Chen L., Shen Y., Luo M., Zuo G., Hu J., Duan D., Nie Y., Shi X., Wang W., Han Y., Li T., Liu Y., Ding M., Deng H. and Xu X., Small molecules blocking the entry of SARS-Co V into host, Journal of Virology. 2004, 78(2)): 11334-11339. |
| Researcher : Lo CM |
| Project Title: | Post-operative adjuvant therapy with recombinant interferon-[alpha] following curative resection of hepatocellular carcinoma: a randomised dose-response controlled trial |
| Investigator(s): | Lo CM, Fan ST |
| Department: | Surgery |
| Source(s) of Funding: | Other Funding Scheme |
| Start Date: | 02/1999 |
| Abstract: |
| To assess the efficacy and safety of interferon [alpha]-2b in reducing the incidence of recurrence after resection of hepatocellular carcinoma. |
| Project Title: | Development of anti-HBsAb in patients with chronic hepatitis B after liver transplantation using lamivudine prophylaxis: the possible role of adoptive immunity |
| Investigator(s): | Lo CM |
| Department: | Surgery |
| Source(s) of Funding: | Other Funding Scheme |
| Start Date: | 01/2000 |
| Abstract: |
| To investigate effects of donor immune status on the development of anti-HBsAb in patients with chronic hepatitis B after liver transplantation. |
| Project Title: | Hepatitis B virus-specific immune response after liver transplantation for chronic hepatitis B using lamivudine prophylaxis |
| Investigator(s): | Lo CM, Fan ST, Lau G |
| Department: | Surgery |
| Source(s) of Funding: | Competitive Earmarked Research Grants (CERG) |
| Start Date: | 10/2002 |
| Abstract: |
| The project attempts to prospectively study the serial changes in HBV-specific immune response after liver transplantation for chronic hepatitis B. This HBV-specific immune response will be correlated with the donor's HBV immune status to clarify the possibility of adoptive immunity transfer through the liver graft. |
| Project Title: | The effect of FTY720 on hepatic ischemia-reperfusion injury in normal and cirrhotic liver |
| Investigator(s): | Lo CM, Man K |
| Department: | Surgery |
| Source(s) of Funding: | Small Project Funding |
| Start Date: | 11/2003 |
| Abstract: |
| To study the effect of a novel immunosuppressive drug FTY720 on hepatic ischemia-reperfusion injury in normal and cirrhotic livers by investigation of (1) cell signalling pathways related to acute phase inflammatory responses, cell survival and apoptosis; (2) hepatic ultrastructural features; and (3) liver function. |
| Project Title: | The significance of hepatic stellate cell activation in marginal liver graft injury |
| Investigator(s): | Lo CM, Man K |
| Department: | Surgery |
| Source(s) of Funding: | Small Project Funding |
| Start Date: | 11/2004 |
| Abstract: |
| To investigate the significance of activation of hepatic stellate cell at the early phase after liver transplantation in marginal graft injury. |
| List of Research Outputs |
| Au W.Y., Liu C.L., Lo C.M., Fan S.T. and Ma E.S.K., Potential role for platelet apheresis for post-liver transplant thrombocytosis complicating portal vein thrombosis, Journal of Clinical Apheresis. 2004, 19(4): 192-196. |
| Chan S.C., Liu C.L., Lo C.M. and Fan S.T., Applicability of histidine-tryptophan-ketoglutarate solution in right lobe adult-to-adult live donor liver transplantation, Liver Transplantation. 2004, 10(11): 1415-1421. |
| Chan S.C., Liu C.L., Lo C.M. and Fan S.T., Primacy of hepatovascular flowmetry in right lobe adult-to-adult live donor liver transplantation (Abstract), The 6th Annual Scientific Meeting, Centre for the Study of Liver Disease, The University of Hong Kong, Hong Kong, 8 January 2005. |
| Chan S.C., Liu C.L., Lo C.M. and Fan S.T., Rapid onset Chilaiditi's sign on top of fulminant hepatic failure (Case Report), Hepatobiliary and Pancreatic Diseases International. 2004, 3(3): 476-477. |
| Chan S.C., Lo C.M., Liu C.L. and Fan S.T., Resurgence of biliary cast syndrome (Images in Liver Transplantation), Liver Transplantation. 2005, 11(2): 242-243. |
| Chok K.S.H., Lam C.M., Li F.K., Ng K.K.C., Poon R.T.P., Lo C.M. and Fan S.T., Management of hepatocellular carcinoma in renal transplant recipients, Journal of Surgical Oncology. 2004, 87(3): 139-142. |
| Erasmo A.A., Crisostomo A.C., Yan L.N., Hong Y.S., Lee K.U. and Lo C.M., Randomized comparison of piperacillin/tazobactam versus imipenem/cilastatin in the treatment of patients with intra-abdominal infection, Asian Journal of Surgery. 2004, 27(3): 227-235. |
| Lee K.W., Man K., Poon R.T.P., Lo C.M., Ng I.O.L. and Fan S.T., Disruption of p53-p21/WAF1 cell cycle pathway contributes to progression and worse clinical outcome of hepatocellular carcinoma, Oncology Reports. 2004, 12(1): 25-31. |
| Li X.L., Man K., Ng K.T., Lee T.K.W., Lo C.M. and Fan S.T., Insulin in UW solution exacerbates hepatic ischemia/reperfusion injury by energy depletion through IRS-2/SREBP-1c pathway, Liver Transplantation. 2004, 10(9): 1173-1182. |
| Li X.L., Man K., Ng T.P., Sun K.W., Lo C.M. and Fan S.T., The influence of phosphatidylinositol 3-kinase/Akt pathway on the ischemic injury during rat liver graft preservation, American Journal of Transplantation. 2005, 5(6): 1264-1275. |
| Lin C.L., Fan S.T., Lo C.M. and Wong J., The role of endoscopic ultrasonography in the management of acute pancreatitis: a prospective randomized study (Invited Lecture), The 12th United European Gastroenterology Week, Prague, Czech Republic, 25-29 September 2004. |
| Liu C.L., Fan S.T., Lo C.M. and Wong J., Clinicobiochemical prediction of biliary cause for acute pancreatitis in the era of endoscopic ultrasonography (Poster Presentation), The 12th United European Gastroenterology Week, Prague, Czech Republic, 25-29 September 2004. |
| Liu C.L., Fan S.T., Lo C.M., Chan S.C., Tso W.K., Ng I.O.L. and Wong J., Hepatic resection for incidentaloma, Journal of Gastrointestinal Surgery. 2004, 8(7): 785-793. |
| Liu C.L., Fan S.T., Lo C.M., Tso W.K. and Wong J., Improved operative and survival outcomes of surgical treatment for hilar cholangiocarcinoma (Abstract), HPB. 2005, 7(1 Suppl): 129. |
| Liu C.L., Fan S.T., Lo C.M., Tso W.K. and Wong J., Improved operative and survival outcomes of surgical treatment for hilar cholangiocarcinoma (Invited Lecture), The 6th Congress of the European Hepato-Pancreato-Biliary Association, Heidelberg, Germany, 25-28 May 2005. |
| Liu C.L., Fan S.T., Lo C.M., Wei W.I., Chan S.C., Yong B.H., Lai C.L. and Wong J., Operative outcomes of adult-to-adult right lobe live donor liver transplantation: a comparative study with cadaveric whole-graft liver transplantation in a single center (Abstract), The 20th International Congress of the Transplantation Society, Vienna, Austria, 5-10 September 2004. |
| Liu C.L., Fan S.T., Lo C.M., Chan S.C., Yong B.H. and Wong J., Safety of donor right hepatectomy without abdominal drainage: a prospective evaluation in 100 consecutive liver donors, Liver Transplantation. 2005, 11(3): 314-319. |
| Lo C.M., Advances in living donor liver transplantation (Invited Lecture), Alimentary Disease Weekend, The University of Hong Kong, Hong Kong, 18-19 September 2004. 2004. |
| Lo C.M., Asian experience in living donor liver transplantation (Abstract), Transplantation Proceedings. 2004, 36(Suppl): 590S. |
| Lo C.M., Asian experience in living donor liver transplantation (Invited Lecture), Transplant Asia, Singapore, 1-4 December 2004. |
| Lo C.M., Asian experience in living donor liver transplantation, Transplant Asia 2004, Singapore. 2004. |
| Lo C.M., Associate Director (1994 - present), Liver Transplant Centre, Queen Mary Hospital, Hospital Authority, Hong Kong. 2005. |
| Lo C.M., Associate Editor (2001 - present), Digestive Surgery. 2005. |
| Lo C.M., Liu C.L. and Fan S.T., Correction of left hepatic vein redundancy in paediatric liver transplantation, Asian Journal of Surgery. 2005, 28(1): 55-57. |
| Lo C.M., Council Member (1997 - present), Hong Kong Society of Transplantation. 2005. |
| Lo C.M., Council Member (2005 - present), The College of Surgeons of Hong Kong. 2005. |
| Lo C.M., Examiner in Licentiate Examination, the Licentiate Committee (1995 - present), Medical Council of Hong Kong. 2005. |
| Lo C.M., Executive Committee Member (1998 - present), International Society for Digestive Surgery. 2005. |
| Lo C.M., Guest Professor (2002 - present), The Peking University Health Science Centre, Peking University First Hospital, China. 2005. |
| Lo C.M., Guest Professor (2004 - present), Army Institute of Hepatobiliary Surgery, Southwest Hospital, Third Military Medical University, China. 2005. |
| Lo C.M., Hepatocellular carcinoma (Invited Lecture), International Symposium on Living Donor Organ Transplantation, Essen, Germany, 2-3 September 2004. 2004. |
| Lo C.M., Hepatocellular carcinoma, International Symposium on Living Donor Organ Transplantation, Essen, Germany. 2004. |
| Lo C.M., Honorary Consultant (1998 - present), Queen Mary Hospital, Hospital Authority, Hong Kong. 2005. |
| Lo C.M., Honorary Consultant (2002 - present), King Faisal Hospital & Research Centre, Kingdom of Saudi Arabia. 2005. |
| Lo C.M., Honorary Consultant (2005 - present), Hong Kong Sanatorium and Hospital, Hong Kong. 2005. |
| Lo C.M., Honorary Senior Consultant (2002 - present), Tung Wah Hospital, Hospital Authority, Hong Kong. 2005. |
| Lo C.M., Fan S.T., Liu C.L., Yong B.H., Wong Y., Lau G., Lai C.L., Ng I.O.L. and Wong J., Lessons learned from one hundred right lobe living donor liver transplants, Annals of Surgery. 2004, 240(1): 151-158. |
| Lo C.M., Liu C.L., Lau G., Chan S.C., Ng I.O.L., Fan S.T. and Wong J., Liver transplantation for chronic hepatitis B with lamivudine-resistant YMDD mutant using add-on adefovir dipivoxil to lamivudine (Abstract), American Journal of Transplantation. 2005, 5(Suppl): 180. |
| Lo C.M., Liu C.L., Lau G., Chan S.C., Ng I.O.L., Fan S.T. and Wong J., Liver transplantation for chronic hepatitis B with lamivudine-resistant YMDD mutant using add-on adefovir dipivoxil to lamivudine (Poster Presentation), American Transplant Congress, Seattle, U.S.A., 21-25 May 2005. |
| Lo C.M., Living donor liver transplantation (Invited Lecture), Asian Pacific Digestive Week, Beijing, China, 4-7 October 2004. |
| Lo C.M., Living donor liver transplantation for hepatocellular carcinoma (Abstract), Asian Journal of Surgery. 2005, 28(Suppl 2): S72. |
| Lo C.M., Living donor liver transplantation for hepatocellular carcinoma (Invited Lecture), The 4th International Meeting on Hepatocellular Carcinoma: Eastern and Western Experiences, Hong Kong, 14-16 December 2004. |
| Lo C.M., Living donor liver transplantation, Asian Pacific Digestive Week 2004, Beijing, China. 2004. |
| Lo C.M., Fan S.T., Liu C.L., Chan S.C., Ng I.O.L. and Wong J., Living donor versus deceased donor liver transplantation for early unresectable hepatocellular carcinoma: same criteria, different outcome (Abstract), HPB. 2005, 7(1 Suppl): 54. |
| Lo C.M., Fan S.T., Liu C.L., Chan S.C., Ng I.O.L. and Wong J., Living donor versus deceased donor liver transplantation for early unresectable hepatocellular carcinoma: same criteria, different outcome (Invited Lecture), The 6th Congress of the European Hepato-Pancreato-Biliary Association, Heidelberg, Germany, 25-28 May 2005. |
| Lo C.M., Fan S.T. and Wong J., Living donor versus deceased donor liver transplantation for early unresectable hepatocellular carcinoma: same criteria, different outcome (Poster Presentation), Digestive Disease Week, Chicago, U.S.A., 14-19 May 2005. |
| Lo C.M., Fan S.T., Liu C.L., Chan S.C., Ng I.O.L. and Wong J., Living donor versus deceased donor liver transplantation for small unresectable hepatocellular carcinoma: same criteria, different outcome (Invited Lecture), The 6th Annual Scientific Meeting, Centre for the Study of Liver Disease, The University of Hong Kong, Hong Kong, 8 January 2005. |
| Lo C.M., Member of Editorial Board (2002 - present), Surgery. 2005. |
| Lo C.M., Member of Editorial Board (2004 - present), World Journal of Surgery. 2005. |
| Lo C.M., Member of Scientific Committee (1998 - present), Cheng Si Yuan China-International Hepatitis Research Foundation . 2005. |
| Lo C.M., Member, Board of Examiners (2002 - present), The College of Surgeons of Hong Kong. 2005. |
| Lo C.M., Member, Exemptions Sub-Committee, the Licentiate Committee (2003 - present), Medical Council of Hong Kong. 2005. |
| Lo C.M., Member, Panel of Assessors (2004 - present), Medical Council of Hong Kong. 2005. |
| Lo C.M., National Delegate (1998 - present), International Society for Digestive Surgery. 2005. |
| Lo C.M., President (2003 - present), Hong Kong Society of Transplantation. 2005. |
| Lo C.M., President (2004 - present), International Society for Digestive Surgery. 2005. |
| Lo C.M., Prevention of hepatitis B after liver transplantation (Abstract), Journal of Gastrointestinal Surgery. 2004, 8(Suppl): 39A. |
| Lo C.M., Prevention of hepatitis B after liver transplantation (Abstract), The 19th World Congress of Digestive Surgery, Yokohama, Japan, 8-11 December 2004. |
| Lo C.M., Program Committee Member (1997 - present), International Society for Digestive Surgery. 2005. |
| Lo C.M., Reviewer, UICC Fellowship Selection Committee (1997 - present), Internaional Union Against Cancer. 2005. |
| Lo C.M., Reviewer, Annals of Surgery. 2005. |
| Lo C.M., Reviewer, Annals of the College of Surgeons of Hong Kong. 2005. |
| Lo C.M., Reviewer, Asian Journal of Surgery. 2005. |
| Lo C.M., Reviewer, British Journal of Surgery. 2005. |
| Lo C.M., Reviewer, Endoscopy. 2005. |
| Lo C.M., Reviewer, Hong Kong Medical Journal. 2005. |
| Lo C.M., Reviewer, Liver Transplantation. 2005. |
| Lo C.M., Steering Committee Member (2002 - present), Asian Pacific Digestive Week. 2005. |
| Lo C.M., Surgical resection for hepatocellular carcinoma (Invited Lecture), The 17th Annual Scientific Meeting of the Hong Kong Association for the Study of Liver Diseases, Hong Kong, 26-27 November 2004. |
| Lo C.M., Surgical resection for hepatocellular carcinoma, International Symposium on Hepatology 2004, the Seventeenth Annual Scientific Meeting of The Hong Kong Association for the Study of Liver Diseases, Hong Kong . 2004. |
| Lo C.M., Technical issues involving the middle hepatic vein, Controversies in Transplantation, Colorado, Denver, USA. 2005. |
| Lo C.M., Technical refinements (Invited Lecture), American Transplant Congress, Seattle, U.S.A., 21-25 May 2005. 2005. |
| Lo C.M., Technical refinements, American Transplant Congress 2005, Seattle, USA . 2005. |
| Lo C.M., World Journal of Surgery, Associate Editor. 2005. |
| Lo C.M., 肝移植術後乙肝復發的預防 (Invited Lecture), 中國廣州南中國區肝臟移植學術研討會, 2004年12月23日, 2004. |
| Lo C.M., 右半肝活體肝移植 (Invited Lecture), 中國北京第四屆21世紀國際外科研討會, 2005年6月10-13日, 2005. |
| Luo Y., Lo C.M., Cheung C.K.Y., Lau G. and Fan S.T., Identification of hepatitis B virus specific lymphocytes in human liver allografts from hepatitis B virus immune donors (Abstract), The 6th Annual Scientific Meeting, Centre for the Study of Liver Disease, The University of Hong Kong, Hong Kong, 8 January 2005. |
| Luo Y., Lo C.M., Cheung C.K.Y., Lau G., Fan S.T. and Wong J., Potential role of resident intrahepatic lymphocytes in adoptive transfer of immunity to hepatitis B virus through liver transplantation (Poster Presentation), Digestive Disease Week, Chicago, U.S.A., 14-19 May 2004. |
| Man K., Lee K.W., Liang T.B., Lo C.M., Fung P.C.W., Tsui H.T., Li X.L., Ng T.P. and Fan S.T., FK409 ameliorates small-for-size liver graft injury by attenuation of portal hypertension and down-regulation of Egr-1 pathway, Annals of Surgery. 2004, 240(1): 159-168. |
| Man K., Ng T.P., Lee K.W., Lo C.M., Sun K.W., Li X., Zhao Y., Ho J.W.Y. and Fan S.T., FTY720 attenuates hepatic ischemia-reperfusion injury in normal and cirrhotic livers, American Journal of Transplantation. 2005, 5(1): 40-49. |
| Man K., Ng T.P., Lo C.M., Sun K.W., Zhao Y., Ho J.W.Y., Lee K.W. and Fan S.T., Hepatic I/R injury on small liver remnant promotes liver tumor growth and metastasis - activation of cell invasion and migration pathways (Abstract), The 20th International Congress of the Transplantation Society, Vienna, Austria, 5-10 September 2004. |
| Man K., Xu A., Xu A., Zhao Y., Lo C.M., Ng T.P., Sun K.W. and Fan S.T., Rescue of small-for-size fatty liver grafts injury by FTY720 and adiponectin combination therapy (Abstract), The 20th International Congress of the Transplantation Society, Vienna, Austria, 5-10 September 2004. |
| Poon R.T.P., Fan S.T., Lo C.M., Liu C.L., Lam C.M., Yuen W.K., Yeung C. and Wong J., Improving perioperative outcome expands the role of hepatectomy in management of benign and malignant hepatobiliary diseases: analysis of 1222 consecutive patients from a prospective database, Annals of Surgery. 2004, 240(4): 698-708. |
| Qian Y.B., Liu C.L., Lo C.M. and Fan S.T., Risk factors for biliary complications after liver transplantation, Archives of Surgery. 2004, 139(10): 1101-1105. |
| Tian M.G., Tso W.K., Lo C.M., Liu C.L. and Fan S.T., Treatment of hepatic artery thrombosis after orthotopic liver transplantation, Asian Journal of Surgery. 2004, 27(3): 213-217. |
| Yang Z., Ho D.W.Y., Lam C.T., Luk J.M.C., Yu W.C., Lo C.M., Poon R.T.P. and Fan S.T., Identification of brain-derived neurotrophic factor (BDNF) in hepatocellular carcinoma - from animal study to clinical management (Abstract), The 6th Annual Scientific Meeting, Centre for the Study of Liver Disease, The University of Hong Kong, Hong Kong, 8 January 2005. |
| Yang Z., Poon R.T.P., Luo Y., Cheung C.K.Y., Ho D.W.Y., Lo C.M. and Fan S.T., Up-regulation of vascualr endothelial growth factor (VEGF) in small-for-size liver grafts enhances macrophage activities through VEGF receptor 2-dependent pathway, Journal of Immunology. 2004, 173(4): 2507-2515. |
| Yong J.L., Lam C.M., Chan O.O., Poon R.T.P., Liu C.L., Lo C.M. and Fan S.T., Better survival in female patients with hepatocellular carcinoma (Abstract), Asian Journal of Surgery. 2005, 28(Suppl 2): S94. |
| Yong J.L., Lam C.M., Chan O.O., Poon R.T.P., Liu C.L., Lo C.M. and Fan S.T., Better survival in female patients with hepatocellular carcinoma (Abstract), The 4th International Meeting on Hepatocellular Carcinoma: Eastern and Western Experiences, Hong Kong, 14-16 December 2004. |
| Zhang H.Y., Nanji A.A., Luk J.M.C., Huang X.R., Lo C.M., Chen Y.X., Yuen S.T., Lan H.Y. and Lau G., Macrophage migration inhibitory factor expression correlates with inflammatory changes in human chronic hepatitis B infection, Liver International. 2005, 25(3): 571-579. |
| Zhao Y., Man K., Lo C.M., Ng T.P., Li X.L., Sun K.W., Lee K.W., Dai X.W. and Fan S.T., Attenuation of small-for-size liver graft injury by FTY720: significance of cell-survival Akt signaling pathway, American Journal of Transplantation. 2004, 4(9): 1399-1407. |
| Researcher : Lo CY |
| Project Title: | Expressing patterns of p16 and CDK4 in thyroid carcinoma |
| Investigator(s): | Lo CY, Lam K.Y. |
| Department: | Surgery |
| Source(s) of Funding: | Seed Funding Programme for Basic Research |
| Start Date: | 02/2004 |
| Completion Date: | 01/2005 |
| Abstract: |
| To identify the expression of p16 and CDK4 in thyroid carcinoma. |
| Project Title: | Establishment of a comprehensive service and registry for hereditary familial endocrinopathy syndromes in Hong Kong |
| Investigator(s): | Lo CY, Lam KSL, Tam S.C.F. |
| Department: | Surgery |
| Source(s) of Funding: | S.K. Yee Medical Foundation - General Award |
| Start Date: | 01/2005 |
| Abstract: |
| To provide a comprehensive clinical, genetic and counseling services for the diagnosis, management, screening and education of familial endocrinopathy syndromes; to establish a registry on all index patients as well as their family members with familial endocrinopathy syndromes in Hong Kong with respect to detailed information including the type of endocrinopathy sydromes, familial pedigrees, patients' demographics, presentation, surgical treatment, pathology of tumours, genetic changes, outcome and follow-up; to improve the standard of care for patients with familial endocrinopathy syndromes through this program; to educate the public and the medical professions advance and the role of genetics in management of these hereditary conditions; to conduct on-going research on familial endocrine diseases by establishing a tissue and serum bank from patients and relatives with familial endocrinopathy sydromes. |
| List of Research Outputs |
| Chan W.F., Lo C.Y., Lam K.Y. and Wan K.Y., The clinicopathologic features and outcome of patients with well-differentiated thryoid carcinoma presenting with recurrent laryngeal nerve palsy, World Journal of Surgery. 2004, 28: 1093-1098. |
| Chang A., Chan W.F., Lo C.Y. and Lam K.S.L., Multiple endocrine neoplasia type 2 in Chinese families, Hong Kong Medical Journal. 2004, 10: 206-9. |
| Ku C.F., Lo C.Y., Chan W.F., Chiu S.W., Fan S.T. and Lam K.S.L., Resection of phaeochromocytoma extending into the right atrium in a patient with multiple endocrine neoplasia type 2A, Hong Kong Medical Journal. 2005, 11(1): 59-62. |
| Ku C.F., Lo C.Y., Chan W.F., Kung A.W.C. and Lam K.S.L., Total thyroidectomy replaces subtotal thyroidectomy as the preferred surgical treatment for Graves' disease, ANZ Journal of Surgery. 2005, 75: 528-531. |
| Lam A., Lo C.Y., Leung P. and Luk J.M.C., High prevalence of cyclooxgenase 2 expression in papillary thyroid carcinoma (Abstract), Pathology Intern. 2004, 54: Suppl A64. |
| Lam K.Y., Lo C.Y. and Wei W.I., Warthin-like tumor variant of the papillary thyroid carcinoma: a case with dedifferentiation (anaplastic changes) and aggressive biological behavior, Endocrine Pathology. 2005, 16: 83-89. |
| Lo C.Y., Ad-hoc reviewer, Annals of College of Surgeons of Hong Kong. 2005. |
| Lo C.Y., Ad-hoc reviewer, Asian Journal of Surgery. 2005. |
| Lo C.Y., Ad-hoc reviewer, Australasian & New Zealand Journal of Surgery. 2005. |
| Lo C.Y., Ad-hoc reviewer, Endoscopy. 2005. |
| Lo C.Y., Ad-hoc reviewer, Expert Reviews of Molecular Diagnostics. 2005. |
| Lo C.Y., Ad-hoc reviewer, Hong Kong Medical Journal. 2005. |
| Lo C.Y., Ad-hoc reviewer, Surgery. 2005. |
| Lo C.Y., Ad-hoc reviewer, The Lancet Oncology. 2005. |
| Lo C.Y., Ad-hoc reviewer, World Journal of Surgery. 2005. |
| Lo C.Y., Ad-hoc reviewers, British Journal of Surgery. 2005. |
| Lo C.Y., Chan W.F., Leung P. and Luk J.M.C., Applicability of tissue aspirate for quick parathyroid hormone assay to confirm parathyroid tissue identity during parathyroidectomy for primary hyperparathyroidism, Archives of Surgery. 2005, 140: 146-149. |
| Lo C.Y., Corresponding member (1998 - present), American Association of Endocrine Surgeons. 2005. |
| Lo C.Y., Council Member (2005 - 2007), International Association of Endocrine Surgeons. 2005. |
| Lo C.Y., Council member (1996 - present), Asian Association of Endocrine Surgeons. 2005. |
| Lo C.Y., Course organizer and speaker, Laparoscopic pancreatectomy, Advanced Laparoscopic GI Surgery Course and Cadaveric Dissection, Queen Mary Hospital and Faculty of Medicine, Hong Kong, 17-18 June 2005. 2005. |
| Lo C.Y., Departmental representative (2001 - present), Pathology Services Subcommittee, Queen Mary Hospital. 2005. |
| Lo C.Y., Lam K.Y., Leung P.P. and Luk J.M.C., High prevalence of cyclooxygenase 2 expression in papillary thyroid carcinoma, European Journal of Endocrinology. 2005, 152(4): 545-550. |
| Lo C.Y., Honorary Consultant (2002 - 2005), Department of Surgery, Queen Mary Hospital, Hong Kong . 2005. |
| Lo C.Y., Honorary Consultant (2005 - present), Department of Surgery, Tung Wah Hospital, Hong Kong West Cluster. 2005. |
| Lo C.Y., Honorary Consultant (2005- present), Hong Kong Sanatorium & Hospital, Happy Valley, Hong Kong. 2005. |
| Lo C.Y., Hyperparathyroidism: Surgical therapeutic options (Invited guest faculty and speaker), 3rd Annual Kuwait Postgraduate Assembly in Surgery, Kuwait, 11-15 December 2004. |
| Lo C.Y., International expert panel, Minimally Invasive Centre, National University Singapore. 2004. |
| Lo C.Y., Invited Speaker, Symposium of "International perspectives in Surgery: Endocrine Surgery in Hong Kong", American College of Surgeons Annual Scientific Congress, New Orleans, U.S.A., 9-15 October 2004. |
| Lo C.Y., Invited faculty, Thyroid Workshop, Putrajaya, Malaysia, November 2004. 2004. |
| Lo C.Y., Invited guest faculty and speaker: • Optimizing the outcome of thyroid surgery: towards zero morbidity• Parathyroid preservation and autotransplantation in thyroid surgery• Papillary thyroid cancers in childhood• Well-differentiated in thyroid cancers• Thyrotoxicosis: Surgery or Radioiodine• MEN II syndrome, 3rd Thyroid workshop organized by Hospital Putrajaya & College of Surgeons, Academy of Medicine, Malaysia (29-30 November, 2004 Hospital Putrajaya, Malaysia). 2004. |
| Lo C.Y., Invited guest faculty and speaker: • Management strategy in Multiple Endocrine Neoplasia (MEN)• Thyrotoxicosis: Surgery or radioactive iodine• Management of multinodular goitre• Hyperparathyroidism: Surgical therapeutic options, 3rd Annual Kuwait Postgraduate Assembly in Surgery. (11-15 December, 2004, Arab Fund for Economic and Social Development Building, Kuwait). 2004. |
| Lo C.Y., Invited guest faculty, The 3rd Annual Kuwait Postgraduate Assembly in Surgery, Kuwait, 11-15 December 2004. 2004. |
| Lo C.Y., Invited speaker in symposium “International perspectives in Surgery: Endocrine Surgery in Hong Kong. , (American College of Surgeons Annual Scientific Congress, New Orleans 9-15 October, 2004). 2004. |
| Lo C.Y., Invited speaker: Laparoscopic pancreatectomy for islet cell tumours , Annual Scientific Meeting Society of Minimal Invasive Surgery (December, 2004 Baptist Hospital, Hong Kong). 2004. |
| Lo C.Y., Invited speaker: Laparoscopy in pancreatic tumor (insulinomas) , ELSA Regional meeting and World Congress of Gasless Laparoscopic Surgery. 26-29 September, 2004, Bali, Indonesia). 2004. |
| Lo C.Y., Invited speaker: Localisation and laparoscopic approach to pancreatic neuroendocrine tumours , Beijing / Hong Kong Joint Forum on General Surgery 2004 , 12 July 2004. 2004. |
| Lo C.Y., Invited speaker: Localisation and laparoscopic approach to pancreatic neuroendocrine tumours , Hong Kong Surgical Summer 2004, 10 July 2004. 2004. |
| Lo C.Y., Invited speaker: “Laparoscopic resection for pancreatic neuroendocrine tumours”. , Laboratory meeting in Division of Endocrine Surgery, University of California at San Francisco, 29 October, 2004). 2004. |
| Lo C.Y., Laparoscopic pancreatectomy (Course organizer and speaker), Advanced Laparoscopic GI Surgery Course and Cadaveric Dissection, Skills Development Centre, Queen Mary Hospital and Faculty of Medicine, 17-18 June 2005. |
| Lo C.Y., Laparoscopic pancreatectomy for islet cell tumours (Invited), Annual Scientific Meeting Society of Minimal Invasive Surgery, Hong Kong Baptist Hospital, Hong Kong, December 2004. |
| Lo C.Y., Laparoscopic resection for pancreatic neuroendocrine tumours (Invited), Laboratory Meeting in Division of Endocrine Surgery, University of California at San Francisco, San Francisco, U.S.A., 29 October 2004. |
| Lo C.Y., Laparoscopy in pancreatic tumor (insulinomas) (Invited), ELSA Regional Meeting and World Congress of Gasless Laparoscopic Surgery, Bali, Indonesia, 26-29 September 2004. |
| Lo C.Y., Localisation and laparoscopic approach to pancreatic neuroendocrine tumours (Invited), Beijing/Hong Kong Joint Forum on General Surgery 2004, Hong Kong, 12 July 2004. |
| Lo C.Y., Localisation and laparoscopic approach to pancreatic neuroendocrine tumours (Invited), Hong Kong Surgical Summer 2004, Hong Kong, 10 July 2004. |
| Lo C.Y., MEN II Syndrome (Invited guest faculty and speaker), 3rd Thyroid Workshop organized by Hospital Putrajaya & College of Surgeons, Academy of Medicine, Malaysia, 29-30 November 2004. |
| Lo C.Y., Management of multinodular goitre (Invited guest faculty and speaker), 3rd Annual Kuwait Postgraduate Assembly in Surgery, Kuwait, 11-15 December 2004. |
| Lo C.Y., Management of primary hyperparathyroidism, Proceeding of The 3rd National Congress of Endocrine and Breast Surgery, Guangzhou, China, 15-19 June 2005. |
| Lo C.Y., Management strategy in Multiple Endocrine Neoplasia (MEN) (Invited guest faculty and speaker), 3rd Annual Kuwait Postgraduate Assembly in Surgery, Kuwait, 11-15 December 2004. |
| Lo C.Y., Membe, Local Organizing Committee, Scientific Subcommittee, 3rd National Congress of Endocrine and Breast Surgery, Guangzhou, China . 2005. |
| Lo C.Y., Member (1987 - present), Hong Kong Medical Association. 2005. |
| Lo C.Y., Member (1992 - present), Asian Surgical Association. 2005. |
| Lo C.Y., Member (1992 - present), Society of Minimal Invasive Surgery. 2005. |
| Lo C.Y., Member (1995 - present), International Association of Endocrine Surgeons. 2005. |
| Lo C.Y., Member (1995 - present), International Surgical Society. 2005. |
| Lo C.Y., Member (1995 - present), Public Doctors' Association. 2005. |
| Lo C.Y., Member (2002 - present), Continued Medical Education Subcommittee, Hong Kong Medical Association. 2005. |
| Lo C.Y., Member (2003 - present), Hospital Authority HK West Institution Review Board. 2005. |
| Lo C.Y., Member (2004 - present), Accreditation Committee, The College of Surgeons of Hong Kong. 2005. |
| Lo C.Y., Member (2004 - present), Minimal Access Surgery Training Coordination Committee, The College of Surgeons of Hong Kong. 2005. |
| Lo C.Y., Member (2004 - present), Scientific Committee, The College of Surgeons of Hong Kong. 2005. |
| Lo C.Y., Member (2004 - present), The Task force for Subspecialty training in General Surgery. 2005. |
| Lo C.Y., Member of Editorial Board (1 February 2002 - present), Asian Journal of Surgery. 2005. |
| Lo C.Y., Member of International Advisory Board (2002 - present), Chinese Journal of Endocrine Surgery. 2005. |
| Lo C.Y., Optimizing the outcome of thyroid surgery: towards zero morbidity (Invited guest faculty and speaker), 3rd Thyroid Workshop by Hospital Putrajaya & College of Surgeons, Academy of Medicine, Malaysia, 29-30 November 2004. |
| Lo C.Y., Chan W.F., Lam K.Y. and Wan K.Y., Optimizing the treatment of AMES high-risk papillary thyroid carcinoma, World Journal of Surgery. 2004, 28: 1103-1109. |
| Lo C.Y., Papillary thyroid cancers in childhood (Invited guest faculty and speaker), 3d Thyroid Workshop oragnized by Hospital Putrajaya & College of Surgeons, Academy of Medicine, Malaysia, 29-30 November 2004. |
| Lo C.Y., Parathyroid preservation and autotransplantation in thyroid surgery (Invited guest faculty and speaker), 3rd Thyroid Workshop organized by Hospital Putrajaya & College of Surgeons, Academy of Medicine, Malaysia, 29-30 November 2004 . 2004. |
| Lo C.Y., President (2004 - 2006), 10th Congress Asian Association fo Endocrine Surgeons. 2005. |
| Lo C.Y., Special lecture: Management of primary hyperparathyroidism , The 3rd National Congress of Endocrine and Breast Surgery, Guangzhou, China, 15-19 June, 2005. 2005. |
| Lo C.Y., Thyrotoxicosis: Surgery or Radioiodine (Invited guest faculty and speaker), 3rd Thyroid Workshop organized by Hospital Putrajaya & College of Surgeons, Academy of Medicine, Malaysia, 29-30 November 2004. |
| Lo C.Y., Thyrotoxicosis: Surgery or radioactive iodine (Invited guest faculty and speaker), 3rd Annual Kuwait Postgraduate Assembly in Surgery, Kuwait, 11-15 December 2004. |
| Lo C.Y., Well-differentiated in thyroid cancers (Invited guest faculty and speaker), 3rd Thyroid Workshop organized by Hospital Putrajaya & College of Surgeons, Academy of Medicine, Malaysia, 29-30 November 2004. |
| Yu X.M., Lo C.Y., Chan W.F., Lam K.Y., Leung P. and Luk J.M.C., Increased expression of Vascular Endothelial Growth Factor-C in papillary thyroid carcinoma predicts cervical lymph node metastasis, Proceedings of the annual meeting of American Association for Cancer Research, Anaheim, California, U.S.A., 16-20 April 2005. |
| Researcher : Loo TY |
| List of Research Outputs |
| Loo T.Y., Cheung M.N.B. and Chow L.W.C., Production of matrix metalloproteinases in specific subpopulations of human-patient breast cancer invading in three dimensional culture system, Life Sciences. 2004, 76: 743-752. |
| Tse E.Y.M., Loo T.Y., Cheung M.N.B., Chow L.W.C. and Cheng C.W.N., Arimidex inhibition on proliferation of human breast solid tumors measured by ATP bioluminescence, Life Sciences. 2004, 76: 827-834. |
| Zhu L., Chow L.W.C., Loo T.Y., Guan X.Y. and Toi M., Her2/neu expression predicts the response to antiaromatase neoadjuvant therapy in primary breast cancer: subgroup analysis from celecoxib antiaromatase neoadjuvant trial, Clinic Cancer Research. 2004, 10(14): 4639-4644. |
| Researcher : Lui VCH |
| Project Title: | Engrailed-Hoxb5 chimaeric transcription repressor: a novel approach to investigate Hoxb5 function in enteric neurons and gut development in transgenic mice |
| Investigator(s): | Lui VCH, Tam PKH, Sham MH |
| Department: | Surgery |
| Source(s) of Funding: | Competitive Earmarked Research Grants (CERG) |
| Start Date: | 09/2002 |
| Abstract: |
| By using the Cre/loxP recombinase technology in transgenic mice, the project team will try to express the en-Hoxb5 repressor gene in mouse embryos and analyse the transgenic mouse embryos for anomalies in the enteric nervous system (ENS) development. This approach will circumvent the problem of functional redundancy such that the function of a specific Hox gene is masked by others, and allow us to address directly the functional role of Hoxb5 in the development of the ENS. |
| Project Title: | Sonic hedgehog in neural crest cell development in gut: a mechanistic study |
| Investigator(s): | Lui VCH, Tam PKH, Sham MH, Vassilis P. |
| Department: | Surgery |
| Source(s) of Funding: | Incentive Award for RGC CERG Fundable But Not Funded Projects |
| Start Date: | 07/2003 |
| Abstract: |
| To investigate the direct and indirect mechanisms by which Sonic Hedgehog (Shh) controls the migration and differentiation of neural crest cells (NCCs) in gut. |
| Project Title: | Cre-inducible disruption of Hedgehog signaling in neural crest cell: a novel approach to study roles of Hedgehog in enteric nerous system development |
| Investigator(s): | Lui VCH, Tam PKH, Sham MH |
| Department: | Surgery |
| Source(s) of Funding: | Small Project Funding |
| Start Date: | 11/2003 |
| Abstract: |
| To generate a DNA construct for Cre-inducible expression of a Ptc1[Delta]loop2 protein; to generate transgenic mice carrying the Ptc1[Delta]loop2 DNA construct by microinjection; transgenic mice will be crossed with a vagal NCC specific Cre mouse strain; to analysis of abnormal phenotypes in the devleoping ENS of the transgenic mutant mice. |
| Project Title: | Conditional knockout of Patched gene in enteric neural crest cells: functional study of the role of Hedgehog signaling in enteric nervous system development |
| Investigator(s): | Lui VCH, Tam PKH, Sham MH, Hui C.C. |
| Department: | Surgery |
| Source(s) of Funding: | Competitive Earmarked Research Grants (CERG) |
| Start Date: | 10/2004 |
| Abstract: |
| To cross floxed Ptc1 mice with a vagal NCC specific Cre mouse strain (b3-IIIa-cre); to analyze the abnormal phenotypes in the developing ENS of the transgenic mutant mice; to analyze the effects of mesenchyme-derived factors on NCCs of the transgenic mutant mice. |
| Project Title: | Investigation of Hoxb5 functions in enteric neurons in late gestation and neonatal period |
| Investigator(s): | Lui VCH, Sham MH, Tam PKH |
| Department: | Surgery |
| Source(s) of Funding: | Small Project Funding |
| Start Date: | 11/2004 |
| Abstract: |
| To investigate the functions of Homeobox gene Hoxb5 in enteric neurons. |
| Project Title: | Conditional knockout of Patched gene in enteric neural crest cells: functional study of the role of Hedgehog signaling in enteric nervous system development |
| Investigator(s): | Lui VCH |
| Department: | Surgery |
| Source(s) of Funding: | Merit Award for RGC CERG Funded Projects |
| Start Date: | 01/2005 |
| Abstract: |
| Refer to hard copy |
| List of Research Outputs |
| Chan K.K., Chen Y.S., Yau T.O., Fu M., Lui V.C.H., Tam P.K.H. and Sham M.H., Hoxb3 vagal neural crest-specific enhancer element for controlling enteric nervous system development, Developmental Dynamics. 2005, 233: 473-483. |
| Chen Y., Lui V.C.H., Rooijen N.V. and Tam P.K.H., Depletion of intestinal resident macrophages prevents ischaemia reperfusion injury in gut, Gut. 2004, 53(12): 1772-1780. |
| Cheng W., Poon K.H., Lui V.C.H., Yong J.L., Law S.Y.K., So K.T., Tse K. and Tam P.K.H., Esophageal atresia and achalasia like esophageal dysmotility, Journal of Pediatric Surgery. 2004, 39(10): 1581-1583. |
| Fu M., Lui V.C.H., Sham M.H., Pachnis V. and Tam P.K.H., Sonic hedgehog regulates the proliferation, differentiation, and migration of enteric neural crest cells in gut., The Journal of Cell Biology. 2004, 166(5): 673-684. |
| Garcia-Barcelo M.M., Lui V.C.H., Fu M., Li L., Scherer S., Herbrick M.A., Van Heurn E. and Tam P.K.H., New HLBX9 mutations in Currarino patients, XXI Annual International Congress of the British Association of Paediatric Surgeons. Oxford, UK, July 27-30, 2004. |
| Garcia-Barcelo M.M., Ganster R.W., Lui V.C.H., Leon Y.Y., So M.T., Lau A.M.F., Fu M., Sham M.H., Knight J., Zannini M.S., Sham P.C. and Tam P.K.H., TTF-1 and RET promoter SNPs: regulation of RET transcription in Hirschsprung's disease, Human Molecular Genetics. 2005, 14(2): 191-204. |
| Ho K.M.T., Li A.Z., Yiu M.K., Lee K.C., Lui V.C.H., Fung P.C.W., Yiu T.F. and Tam P.K.H., Altered expression of aquaporin-2 in human explants with chronic renal allograft dysfunction, BJU International. 2005, 95: 1104-1108. |
| Law M.L., Ngan E.S.W., Lui V.C.H., Tam P.K.H. and Sham M.H., The role of Sox 10 on survival and proliferation of enteric neural crest stem cells, 3rd Annual Meeting of International Society for Stem Cell Research.. 2005. |
| Lui V.C.H., Fu M., Sham M.H. and Tam P.K.H., Sonic hedgehog (SHH) promotes proliferation and maintains multi-potency of enteric neural crest stem cells (NCSCs), 51st Annual International Congress of British Association of Paediatric Surgeons, Oxford, U.K. 27-30 July 2004. |
| Lui V.C.H., Fu M., Sham M.H. and Tam P.K.H., Sonic hedgehog (SHH) regulates the migration and differentiation of the enteric neural crest stem cells (NCSCs) in gastrointestinal tract, 51st Annual International Congress of British Association of Paediatric Surgeons, Oxford, U.K. 27-30 July 2004. |
| Ren Y., Lin C.L., Li Z., Chen X.Y., Huang X., Lui V.C.H., Nicholls J.M., Lan H.Y. and Tam P.K.H., Up-regulation of macrophage migration inhibitory factor in infants with acute neonatal necrotizing enterocolitis, Histopathology. 2005, 46(6): 659-667. |
| Researcher : Lui WM |
| List of Research Outputs |
| Chan K.H., Cheung R.T.F., Lui W.M., Mak W. and Ho S.L., Cerebral venous thrombosis in a gentleman with fever, convulsion and frontotemporal haemorrhages, Journal of Clinical Neuroscience. 2005, 12: 186-188. |
| Researcher : Luk JMC |
| Project Title: | Prevention of endotoxin-mediated liver injury by recombinant integrin subunit (RIS), Anti-CD18 Fv and TW-PS22 |
| Investigator(s): | Luk JMC, Fan ST |
| Department: | Surgery |
| Source(s) of Funding: | Competitive Earmarked Research Grants (CERG) |
| Start Date: | 09/2002 |
| Abstract: |
| The project attempts to exploit new approaches for preventing endotoxin-mediated liver injury in experimental sepsis and ischemia/reperfusion (I/R) animal models. |
| Project Title: | Structural and functional of VAD1.3-a novel testis-specific gene in spermatogenesis |
| Investigator(s): | Luk JMC, Ngan ESW, Yeung WSB |
| Department: | Surgery |
| Source(s) of Funding: | Incentive Award for RGC CERG Fundable But Not Funded Projects |
| Start Date: | 07/2003 |
| Abstract: |
| To characterize the structure and function of VAD1.3, a novel gene that has not been studied before, by employing immunological, structural and transgenic approaches; to elucidate its physiologic function(s) in the regulatory mechanisms of spermatogenesis. |
| Project Title: | Adrenomedullin peptide in hepatic cirrhosis: regulatory mechanism in hemodynamic changes |
| Investigator(s): | Luk JMC, Hwang ISS, Tang F |
| Department: | Surgery |
| Source(s) of Funding: | Seed Funding Programme for Basic Research |
| Start Date: | 02/2004 |
| Completion Date: | 01/2005 |
| Abstract: |
| To study the gene expression, level of AM and receptor mRNA in liver and the vasculature of cirrhotic rat; to determine the correlation between AM and parameters of ascites formation in cirrhotic rat (plasma renin activity, aldosterone concentration and sympathetic nervous system activity); to identify the types of cells that secret AM in rat liver and the morphological changes of AM antigen in cirrhotic liver; to study the relationship between changes in AM and nitric oxide (NO) generation (and carbon dioxide generation) in cirrhotic rat model. |
| Project Title: | Target delivery of glyrrhetinic acid to hepatic stellate cells in liver injury |
| Investigator(s): | Luk JMC |
| Department: | Surgery |
| Source(s) of Funding: | Small Project Funding |
| Start Date: | 11/2004 |
| Abstract: |
| To synthesize M6P26-HSA conjugated with GA as a carrier for HSC; to determine the organ distribution of the GA and its localization at HSCs in situ and in vitro; to evaluate the anti-fribotic activities of the neoglycoconjugate GA in HSC. |
| Project Title: | Development of Proteomic SELDI-based immunoassay for early detection and screening of liver malignancy |
| Investigator(s): | Luk JMC, Fan S T, Che CM |
| Department: | Surgery |
| Source(s) of Funding: | Seed Funding Programme for Applied Research |
| Start Date: | 06/2005 |
| Abstract: |
| Hepatocellular carcinoma (HCC) is the fifth most common cancer worldwide, with about half a million new cases and almost as many deaths per year. Early diagnosis has been proven to be important for prognosis. However, there is no reliable diagnosis prior to late stages of disease and no hope for cure except surgery.Objectives & Deliverables:1. To identify and characterize potential biomarkers for HCC by proteomic technology. 2. To generate monoclonal antibodies directed against biomarkers specific for cirrhotic liver and/or HCC.3. To develop SELDI-based immuno-diagnostic test for early detection of HCC as well as for disease monitoring. |
| List of Research Outputs |
| Ho D.W.Y., Luk J.M.C. and Fan S.T., Plasma proteomic profiling and identification of circulating biomarkers for monitoring fulminant hepatic failure in a porcine model (Abstract), HUPO 3rd Annual World Congress, Beijing, China, 25-27 October 2004. |
| Ho D.W.Y., Luk J.M.C. and Fan S.T., Plasma proteomic profiling and identification of circulating biomarkers for monitoring fulminant hepatic failure, Molecular and Cellular Proteomics. 2004, 3(10): S112, 8.14. |
| Ho D.W.Y., Yang Z., Lau C.K., To J.Y.T., Luk J.M.C. and Fan S.T., The therapeutic role of cardiotrophin-1 in a rat model with fulminant hepatic failure (Abstract), The 6th Annual Scientific Meeting, Centre for the Study of Liver Disease, The University of Hong Kong, Hong Kong, 8 January 2005. |
| Ko S., Luk J.M.C., Wong W.Y., Leung S.Y. and Chu K.M., CDX2 co-localizes with liver-intestine cadherin in intestinal metaplasia and adenocarcinoma of stomach, 6th International Gastric Cancer of Congress, Yokohama, Japan, 4-7 May 2005. |
| Ko S., Chu K.M., Luk J.M.C., Wong W.Y., Yuen S.T., Leung S.Y. and Wong J., CDX2 co-localizes with liver-intestine cadherin in intestinal metaplasia and adenocarcinoma of stomach, Journal of Pathology . 2005, 205: 615-622. |
| Lam A., Lo C.Y., Leung P. and Luk J.M.C., High prevalence of cyclooxgenase 2 expression in papillary thyroid carcinoma (Abstract), Pathology Intern. 2004, 54: Suppl A64. |
| Lee C.Y.L., Xu J., Lee C.K.F., Luk J.M.C., Lee W.W.M. and Yeung W.S.B., Mechanism of actions of human oviduct derived embryotrophic factor-3 (ETF3) or iC3b on mouse preimplantation embryo development, The 37th Annual Meeting of The Society For The Study of Reproduction, University of British Columbia, Vancouver, Canada, August 1-4, 2004. |
| Lin M.C., Lee N., Zheng N., Yang P.H., Wong O.G., Kung H.F., Luk J.M.C. and Lau G., Tumor necrosis factor-alpha-induced protein 1 and immunity to hepatitis B virus, World J Gastroenterol. 2005. |
| Lo C.Y., Chan W.F., Leung P. and Luk J.M.C., Applicability of tissue aspirate for quick parathyroid hormone assay to confirm parathyroid tissue identity during parathyroidectomy for primary hyperparathyroidism, Archives of Surgery. 2005, 140: 146-149. |
| Lo C.Y., Lam K.Y., Leung P.P. and Luk J.M.C., High prevalence of cyclooxygenase 2 expression in papillary thyroid carcinoma, European Journal of Endocrinology. 2005, 152(4): 545-550. |
| Luk J.M.C., Lam B.Y.H., Yi X., Peng J., Leng X. and Fan S.T., Applicability of proteomic biomarkers set to distinguish hepatocellular carcinoma from non-tumor and healthy liver tissues, 4th HUPO Annual Congress, Munich, Germany, 28 August - 1 September 2005. |
| Luk J.M.C., Lam B.K.Y., Yi X., Peng J., Leng X. and Fan S.T., Applicability of proteomic biomarkers set to distinguish hepatocellular carcinoma from non-tumor and healthy liver tissues, Molecular and cellular proteomics. 2005, 4(8) suppl. 13.55: S119. |
| Luk J.M.C., Applicability of proteomic biomarkers set to distinguish hepatocellular carcinoma from non-tumor and healthy liver tissues, The 1st International Congress of Comprehensive Diagnosis and Interventional Therapy on Hepatocellular Carcinoma (HCC), Shanghai, China, 25-26 June 2005. |
| Luk J.M.C. and Fan S.T., Applicability of proteomic biomarkers set to distinguish hepatocellular carcinoma from non-tumor and healthy liver tissues, The XXL Symposium on Molecular Control of Cancer, Cold Spring Harbor Lab, New York, U.S.A., 1-5 June 2005. |
| Luk J.M.C., Course Coordinator and Organizer (2002 - present), MMPH6138 & SURG CM016 Module, Laboratory Animal Handling & Surgical Techniques, Faculty of Medicine, The University of Hong Kong. 2005. |
| Luk J.M.C., Lam C.T., Lam B.H., Siu A., Che C.M. and Fan S.T., Dyregulation of chaperone proteins Hsp27, Hsp70 and Grp78 in hepatocellular carcinoma (Abstract), The 3rd HUPO Annual World Congress, Beijing, China, 25-27 October . 2004. |
| Luk J.M.C., Lam C.T., Lam B.H., Siu A., Che C.M. and Fan S.T., Dysregulation of chaperone proteins Hsp27, Hsp70 and Grp78 in hepatocellular carcinoma, Molecular and Cellular Proteomics. 2004, 3(10): S114, 8.19. |
| Luk J.M.C., Lee N.P., Ma J. and Fan S.T., Expression of recombinant integrin b2 subunit that ameliorate LPS binding activity to endothelial cell, FASEB Annual Meeting EB/IUPS Conference, San Diego, U.S.A., 21 March - 6 April 2005. |
| Luk J.M.C., Lee N.P., Klickstein L.B. and Fan S.T., Generation and application of anti-CD18mAb and Fv derivatives for preventing LPS-activated leukocyte adhesion, The Protein Engineering Summit: Phage display, recombinant antibody, and monoclonal antibody, Cambridge Health Institute, Boston, U.S.A., 16 - 20 May 2005. |
| Luk J.M.C., Wang P., Wang J. and Fan S.T., Hepatic potential of bone marrow stromal cells after co-culture with damaged liver tissues and intraportal transplantation in cirrhotic liver, The 34th Annual Scientific Meeting of the Australasian Society for Immunology and 8th International Conference on Human Leucocyte Differentiation Antigens (HLDA8), Adelaide, Australia, 12-16 December 2004. |
| Luk J.M.C., Wang P., Wang J., Lau G. and Fan S.T., Hepatocyte-like phenotypes of bone marrow stromal cells after co-culture with damaged liver tissues and intraportal transplantation in cirrhotic liver (Abstract), The 55th Annual Meeting of the American Association for the Study of Liver Diseases, Boston, USA, 29 October – 2 November 2004. |
| Luk J.M.C., Wang P.P., Wang J., Lau G.K. and Fan S.T., Hepatocyte-like phenotypes of bone marrow stromal cells after co-culture with damaged liver tissues and intraportal transplantation in cirrhotic liver, Hepatology. 2004, 40 (Supplement 1): LB-16, 733A. |
| Luk J.M.C., Peng J.R., Leng X.S. and Fan S.T., Molecular classification of hepatocellular carcinoma by proteomic expression profiling (Abstract), HUPO 3rd Annual World Congress, Beijing, China, 25-27 October 2004. |
| Luk J.M.C., Lam B.K.Y., Lam C.T., Siu F.M., Ho D.W.Y., Yu W.C., Peng J.R., Che C.M., Leng X.S. and Fan S.T., Molecular classification of hepatocellular carcinoma by proteomic expression profiling (Abstract), The 6th Annual Scientific Meeting, Centre for the Study of Liver Disease, The University of Hong Kong, Hong Kong, 8 January 2005. |
| Luk J.M.C., Peng J.R., Leng X.S. and Fan S.T., Molecular classification of hepatocellular carcinoma by proteomic expression profiling, Molecular and Cellular Proteomics. 2004, 3(10): S144, 8.18. |
| Luk J.M.C., Organizer, Genomics, Proteomics and Therapeutics in Cancer Research Conference, Centre of Cancer Research, Faculty of Medicine, The University of Hong Kong, 20-21 October 2004. 2004. |
| Luk J.M.C., Lee C.K.F., Su Y.C.F., Lam C.T., Hu M.Y., He Q., Lau G., Wong W.S. and Fan S.T., Proteomic identification of Ku70/Ku80 autoantigen recognized by monoclonal antibody against hepatocellular carcinoma (Abstract), HUPO 3rd Annual World Congress, Beijing, China, 25-27 October 2004. |
| Luk J.M.C., Su Y.C.F., Lam C.T., Lee C.K.F., Hu M.Y., He Q., Lau G., Wong F.W.S. and Fan S.T., Proteomic identification of Ku70/Ku80 autoantigen recognized by monoclonal antibody against hepatocellular carcinoma, Proteomics. 2005, 5(7): 1980-1986. |
| Luk J.M.C., Cheung N., Lam B.Y.H. and Fan S.T., Proteomic roadmap of mouse liver development from embryo to adult, Molecular and cellular proteomics. 2005, 4(8) Suppl 8.3: S77. |
| Luk J.M.C., Cheung N., Lam B.K.Y. and Fan S.T., Proteomic roadmap of mouse liver development from embryo to adult, The 4th HUPO Annual Congress, Munich, Germany, 28 August - 1 September 2005. |
| Luk J.M.C., Lee C.K.F., Wang X. and Fan S.T., Recognition of monoclonal antibodies against alternative splicing of liver intestine cadherin (Cdh17) in hepatocellular carcinoma , The 34th Annual Scientific Meeting of the Australasian Society for Immunology and 8th International Conference on Human Leucocyte Differentiation Antigens (HLDA8), Adelaide, Australia, 12-16 December 2004. |
| Luk J.M.C., Reviewer (1997 - present), Journal of Immunology. 2005. |
| Luk J.M.C., Reviewer (2003 - present), Asian Journal of Surgery. 2005. |
| Luk J.M.C., Reviewer (2004 - present), American Journal of Phsyiology. 2005. |
| Luk J.M.C., Reviewer (2004 - present), Analytical Biochemistry. 2005. |
| Luk J.M.C., Reviewer (2004 - present), FEBS Letters. 2005. |
| Luk J.M.C., Reviewer (2004 - present), Journal of Biomedical Science. 2005. |
| Luk J.M.C., Reviewer (2004 - present), Journal of Gastroenterology & Hepatology. 2005. |
| Luk J.M.C., Reviewer (2004 - present), Journal of Hepatology. 2005. |
| Luk J.M.C., Reviewer (2004 - present), Liver International. 2005. |
| Luk J.M.C., Reviewer (2005 - present), Cancer Investigation. 2005. |
| Luk J.M.C., Reviewer (2005 - present), Oncogene. 2005. |
| Luk J.M.C., Reviewer (2005 - present), Proteomics. 2005. |
| Luk J.M.C., Tong M.K., Mok B.B.W., Tam P.C., Yeung W.S.B. and Lee C.K.F., Sp 1 site is crucial for the mouse claudin-19 gene expression in the kidney cells, FEBS Letters . 2004, 578: 251-256. |
| Wang P.P., Wang J.H., Yan Z.P., Hu M., Lau G., Fan S.T. and Luk J.M.C., Expression of hepatocyte-like phenotypes in bone marrow stromal cells after HGF induction, Biochemical and Biophysical Research Communications. 2004, 320(3): 712-716. |
| Wang X., Luk J.M.C., Leung P.L., Wong W.Y., Stanbridge E.J. and Fan S.T., Alternative mRNA splicing of liver intestine-cadherin in hepatocellular carcinoma, Clinical Cancer Research. 2005, 11(2 Pt 1): 483-489. |
| Wang X., Luk J.M.C., Leung P.L., Ho D.W.Y. and Fan S.T., Overexpressing LI-cadherin genetic polymorphisms (651C/T, IVS6+35A/G) is associated with susceptibility to HCC (Abstract), The 4th International Meeting on Hepatocellular Carcinoma: Eastern and Western Experiences, Hong Kong, 14-16 December 2004. |
| Wang X., Luk J.M.C., Leung P.L., Ho D.W.Y. and Fan S.T., Overexpression LI-cadherin genetic polymorphisms (651C/T, IVS6+35A/G) is associated with susceptibility to HCC (Abstract), Asian Journal of Surgery. 2005, 28(Suppl 2): S107. |
| Wang X., Luk J.M.C., Leung P.L. and Fan S.T., Overexpression of LI-cadherin genetic polymorphisms (651C/T, IVS6+35A/G) is associated with susceptibility to hepatocellular carcinoma (Abstract), The 6th Annual Scientific Meeting, Centre for the Study of Liver Disease, The University of Hong Kong, Hong Kong, 8 January 2005. |
| Xu J., Lee C.Y.L., Lee C.K.F., Kwok K.L., Lee W.W.M., Luk J.M.C. and Yeung W.S.B., Embryotrophic factor-3 from human oviductal cells enhances proliferation, suppresses apoptosis and stimulates the expression of the b1 submit of sodium-potassium ATPase in mouse embryos, Human Reproduction. 2004, 19(12): 2919-2926. |
| Yang Z., Ho D.W.Y., Lam C.T., Luk J.M.C., Lum C.T., Yu W.C., Poon R.T.P. and Fan S.T., Identification of brain-derived neurotrophic factor (BDNF) as a potential therapeutic target in hepatocellular carcinoma (Abstract), The 4th International Meeting on Hepatocellular Carcinoma: Eastern and Western Experiences, Hong Kong, 14-16 December 2004. |
| Yang Z., Ho D.W.Y., Lam C.T., Luk J.M.C., Yu W.C., Lo C.M., Poon R.T.P. and Fan S.T., Identification of brain-derived neurotrophic factor (BDNF) in hepatocellular carcinoma - from animal study to clinical management (Abstract), The 6th Annual Scientific Meeting, Centre for the Study of Liver Disease, The University of Hong Kong, Hong Kong, 8 January 2005. |
| Yang Z., Ho D.W.Y., Lam C.T., Luk J.M.C., Lum C.T., Yu W.C., Poon R.T.P. and Fan S.T., Identification of brain-derived neurotrophic factor as a novel functional protein in hepatocellular carcinoma, Cancer Research. 2005, 65(1): 219-225. |
| Yang Z., Ho D.W.Y., Lam C.T., Luk J.M.C., Poon R.T.P. and Fan S.T., The potential role of allograft inflammatory factor 1 (AIF-1) in macrophage activation in small-for-size liver transplantation, The 20th International Congress of the Transplantation Society, Vienna, Austria, 5-10 September 2004. |
| Yu X.M., Lo C.Y., Chan W.F., Lam K.Y., Leung P. and Luk J.M.C., Increased expression of Vascular Endothelial Growth Factor-C in papillary thyroid carcinoma predicts cervical lymph node metastasis, Proceedings of the annual meeting of American Association for Cancer Research, Anaheim, California, U.S.A., 16-20 April 2005. |
| Zhang H.Y., Nanji A.A., Luk J.M.C., Huang X.R., Lo C.M., Chen Y.X., Yuen S.T., Lan H.Y. and Lau G., Macrophage migration inhibitory factor expression correlates with inflammatory changes in human chronic hepatitis B infection, Liver International. 2005, 25(3): 571-579. |
| Researcher : Luo Y |
| List of Research Outputs |
| Luo Y., Lo C.M., Cheung C.K.Y., Lau G. and Fan S.T., Identification of hepatitis B virus specific lymphocytes in human liver allografts from hepatitis B virus immune donors (Abstract), The 6th Annual Scientific Meeting, Centre for the Study of Liver Disease, The University of Hong Kong, Hong Kong, 8 January 2005. |
| Luo Y., Lo C.M., Cheung C.K.Y., Lau G., Fan S.T. and Wong J., Potential role of resident intrahepatic lymphocytes in adoptive transfer of immunity to hepatitis B virus through liver transplantation (Poster Presentation), Digestive Disease Week, Chicago, U.S.A., 14-19 May 2004. |
| Yang Z., Poon R.T.P., Luo Y., Cheung C.K.Y., Ho D.W.Y., Lo C.M. and Fan S.T., Up-regulation of vascualr endothelial growth factor (VEGF) in small-for-size liver grafts enhances macrophage activities through VEGF receptor 2-dependent pathway, Journal of Immunology. 2004, 173(4): 2507-2515. |
| Researcher : Ma J |
| List of Research Outputs |
| Luk J.M.C., Lee N.P., Ma J. and Fan S.T., Expression of recombinant integrin b2 subunit that ameliorate LPS binding activity to endothelial cell, FASEB Annual Meeting EB/IUPS Conference, San Diego, U.S.A., 21 March - 6 April 2005. |
| Researcher : Man K |
| Project Title: | The anit-cancer effect of FTY720 on liver tumors in vitro and in vivo |
| Investigator(s): | Man K, Fan ST, Ho JWY |
| Department: | Surgery |
| Source(s) of Funding: | Seed Funding Programme for Basic Research |
| Start Date: | 02/2004 |
| Abstract: |
| To investigate the anti-cancer effect of FTY720 on liver tumors in vitro and in vivo by detection of different cell signalling pathways including cell survival, apoptosis, and cell invasion and migration, as well as the comparison of tumor growth and metastasis. |
| Project Title: | The significance of graft size on tumor recurrence after liver transplantation |
| Investigator(s): | Man K, Fan ST, Lo CM |
| Department: | Surgery |
| Source(s) of Funding: | Competitive Earmarked Research Grants (CERG) |
| Start Date: | 09/2004 |
| Abstract: |
| To test the hypothesis that small-for-size grafts are more susceptible to tumor recurrence after liver transplantation in a rat liver transplantation model; to clarify the mechanism of tumor recurrence. |
| Project Title: | The significance of graft size on tumor recurrence after liver transplantation |
| Investigator(s): | Man K |
| Department: | Surgery |
| Source(s) of Funding: | Merit Award for RGC CERG Funded Projects |
| Start Date: | 01/2005 |
| Abstract: |
| Refer to hard copy |
| Project Title: | The effect of Rapamycin on ischemia/reperfusion injury in liver transplantation using small-for-size grafts in a cirrhotic rat model - the investigation of the hepatic stellate cell activation and ROCK pathway |
| Investigator(s): | Man K, Lo CM, Fan ST |
| Department: | Surgery |
| Source(s) of Funding: | Seed Funding Programme for Basic Research |
| Start Date: | 01/2005 |
| Abstract: |
| Refer to hard copy |
| List of Research Outputs |
| Chua C.W., Lee T.W., Ling M.T., Man K., Ho J.W.Y., Ho J.W.Y., Ho J.W.Y., Ho J.W.Y., Ho J.W.Y., Wang X. and Wong Y.C., FTY720, a fungus metabolite, inhibits in vivo growth of androgen-independent prostate cancer, International Journal of Cancer. 2005, Equib ahead of print. |
| Ho J.W.Y., Man K., Sun K.W., Poon R.T.P. and Fan S.T., Effective low dose combined-drug treatment using FTY720 and Gleeve in hepatocellular carcinoma (Abstract), The 6th Annual Scientific Meeting, Centre for the Study of Liver Disease, The University of Hong Kong, Hong Kong, 8 January 2005. |
| Ho J.W.Y., Man K., Sun K.W., Poon R.T.P. and Fan S.T., Effective low dose combined-drug treatment using FTY720 and Gleevec in hepatocellular carcinoma (Abstract), Asian Journal of Surgery. 2005, 28(Suppl 2): S82. |
| Ho J.W.Y., Man K., Sun K.W., Poon R.T.P. and Fan S.T., Effective low dose combined-drug treatment using FTY720 and Gleevec in hepatocellular carcinoma (Abstract), The 4th International Meeting on Hepatocellular Carcinoma: Eastern and Western Experiences, Hong Kong, 14-16 December 2004. |
| Lee K.W., Man K., Poon R.T.P., Lo C.M., Ng I.O.L. and Fan S.T., Disruption of p53-p21/WAF1 cell cycle pathway contributes to progression and worse clinical outcome of hepatocellular carcinoma, Oncology Reports. 2004, 12(1): 25-31. |
| Lee K.W., Man K., Ho J.W.Y., Sun K.W., Ng T.P., Wang X., Wong Y.C., Ng I.O.L., Xu R. and Fan S.T., FTY720 induces apoptosis of human hepatoma cell lines through PI3-K-mediated Akt dephosphorylation, Carcinogenesis. 2004, 25(12): 2397-2405. |
| Lee K.W., Man K. and Fan S.T., Significance of Rac signaling pathway in HCC cell motility: implication for a new therapeutic treatment (Abstract), Asian Journal of Surgery. 2005, 28(Suppl 2): S90. |
| Lee K.W., Man K. and Fan S.T., Significance of Rac signaling pathway in HCC cell motility: implication for a new therapeutic treatment (Abstract), The 4th International Meeting on Hepatocellular Carcinoma: Eastern and Western Experiences, Hong Kong, 14-16 December 2004. |
| Lee K.W., Man K. and Fan S.T., Significance of Rac signaling pathway in hepatocellular carcinoma cell motility: implication for a new therapeutic treatment by FTY720 (Abstract), The 6th Annual Scientific Meeting, Centre for the Study of Liver Disease, The University of Hong Kong, Hong Kong, 8 January 2005. |
| Lee K.W., Man K., Ho J.W.Y., Wang X., Poon R.T.P., Sun K.W., Ng T.P., Ng I.O.L., Xu R. and Fan S.T., Significance of the Rac signaling pathway in HCC cell motility: implications for a new therapeutic target, Carcinogenesis. 2005, 26(3): 681-687. |
| Li X.L., Man K., Ng K.T., Lee T.K.W., Lo C.M. and Fan S.T., Insulin in UW solution exacerbates hepatic ischemia/reperfusion injury by energy depletion through IRS-2/SREBP-1c pathway, Liver Transplantation. 2004, 10(9): 1173-1182. |
| Li X.L., Man K., Ng T.P., Sun K.W., Lo C.M. and Fan S.T., The influence of phosphatidylinositol 3-kinase/Akt pathway on the ischemic injury during rat liver graft preservation, American Journal of Transplantation. 2005, 5(6): 1264-1275. |
| Man K., Lee K.W., Liang T.B., Lo C.M., Fung P.C.W., Tsui H.T., Li X.L., Ng T.P. and Fan S.T., FK409 ameliorates small-for-size liver graft injury by attenuation of portal hypertension and down-regulation of Egr-1 pathway, Annals of Surgery. 2004, 240(1): 159-168. |
| Man K., Ng T.P., Lee K.W., Lo C.M., Sun K.W., Li X., Zhao Y., Ho J.W.Y. and Fan S.T., FTY720 attenuates hepatic ischemia-reperfusion injury in normal and cirrhotic livers, American Journal of Transplantation. 2005, 5(1): 40-49. |
| Man K., Ng T.P., Lo C.M., Sun K.W., Zhao Y., Ho J.W.Y., Lee K.W. and Fan S.T., Hepatic I/R injury on small liver remnant promotes liver tumor growth and metastasis - activation of cell invasion and migration pathways (Abstract), The 20th International Congress of the Transplantation Society, Vienna, Austria, 5-10 September 2004. |
| Man K., Ng T.P. and Fan S.T., Hepatic I/R injury on small liver remnant promotes liver tumour growth and metastasis - activation of cell invasion and migration pathway (Abstract), The 4th International Meeting on Hepatocellular Carcinoma: Eastern and Western Experiences, Hong Kong, 14-16 December 2004. |
| Man K., Ng T.P. and Fan S.T., Hepatic I/R injury on small liver remnant promotes liver tumour growth and metastasis - activation of cell invasion and mirgration pathway (Abstract), Asian Journal of Surgery. 2005, 28(Suppl 2): S83. |
| Man K., Xu A., Xu A., Zhao Y., Lo C.M., Ng T.P., Sun K.W. and Fan S.T., Rescue of small-for-size fatty liver grafts injury by FTY720 and adiponectin combination therapy (Abstract), The 20th International Congress of the Transplantation Society, Vienna, Austria, 5-10 September 2004. |
| Pang R.W.C., Lee K.W., Man K., Poon R.T.P., Fan S.T., Kwong Y.L. and Tse E.W.C., RNAi-mediated silencing of PIN1 inhibits HCC tumorigenicity (Abstract), The 96th Annual Meeting of the American Association for Cancer Research, Anaheim, California, U.S.A., 16-20 April 2005. |
| Pang W.C., Lee K.W., Man K., Poon R.T.P., Fan S.T., Kwong Y.L. and Tse E.W.C., Inhibition of hepatocellular carcinoma tumourigenicity by RNAi-mediated PIN1 silencing (Abstract), The 6th Annual Scientific Meeting, Centre for the Study of Liver Disease, The University of Hong Kong, Hong Kong, 8 January 2005. |
| Pang W.C., Lee K.W., Man K., Poon R.T.P., Fan S.T., Kwong Y.L. and Tse E.W.C., RNAi-mediated PIN1 silencing inhibits HCC trumourigenicity (Abstract), Asian Journal of Surgery. 2005, 28(Suppl 2): S84. |
| Pang W.C., Lee K.W., Man K., Poon R.T.P., Fan S.T., Kwong Y.L. and Tse E.W.C., RNAi-mediated PIN1 silencing inhibits HCC tumourigenicity (Abstract), The 4th International Meeting on Hepatocellular Carcinoma: Eastern and Western Experiences, Hong Kong, 14-16 December 2004. |
| Pang W.C., Lee K.W., Man K., Poon R.T.P., Fan S.T., Kwong Y.L. and Tse E.W.C., RNAi-mediated silencing of PIN1 inhibits HCC tumorigenicity, The 11th Hong Kong International Cancer Congress, Hong Kong, 10-12 November, 2004. |
| Sun X., Krissansen G.W., Fung P.C.W., Xu S., Shi J., Man K., Fan S.T. and Xu R., Anti-angiogenic therapy subsequent to adeno-associated-virus-mediated immunotherapy eradicates lymphomas that disseminate to the liver, International Journal of Cancer. 2004, 113(4): 670-677. |
| Zhao Y., Man K., Lo C.M., Ng T.P., Li X.L., Sun K.W., Lee K.W., Dai X.W. and Fan S.T., Attenuation of small-for-size liver graft injury by FTY720: significance of cell-survival Akt signaling pathway, American Journal of Transplantation. 2004, 4(9): 1399-1407. |
| Zhou C., Ling M.T., Lee T.K.W., Man K., Wang X. and Wong Y.C., FTY720, a fungus metabolite, inhibits invasion ability of androgen independent prostate cancer cells through inactivation of RhoA-GTPase, Proceedings of the American Association for Cancer Research, April 2005. 46: Abstract No. 669. |
| Researcher : Ng KCK |
| List of Research Outputs |
| Ng K.C.K., Local and systemic effects of hepatic radiofrequency ablation in animal models, Thesis, Doctor of Philosophy, The University of Hong Kong. 2004. |
| Researcher : Ng TP |
| List of Research Outputs |
| Lee K.W., Man K., Ho J.W.Y., Sun K.W., Ng T.P., Wang X., Wong Y.C., Ng I.O.L., Xu R. and Fan S.T., FTY720 induces apoptosis of human hepatoma cell lines through PI3-K-mediated Akt dephosphorylation, Carcinogenesis. 2004, 25(12): 2397-2405. |
| Lee K.W., Man K., Ho J.W.Y., Wang X., Poon R.T.P., Sun K.W., Ng T.P., Ng I.O.L., Xu R. and Fan S.T., Significance of the Rac signaling pathway in HCC cell motility: implications for a new therapeutic target, Carcinogenesis. 2005, 26(3): 681-687. |
| Li X.L., Man K., Ng T.P., Sun K.W., Lo C.M. and Fan S.T., The influence of phosphatidylinositol 3-kinase/Akt pathway on the ischemic injury during rat liver graft preservation, American Journal of Transplantation. 2005, 5(6): 1264-1275. |
| Man K., Lee K.W., Liang T.B., Lo C.M., Fung P.C.W., Tsui H.T., Li X.L., Ng T.P. and Fan S.T., FK409 ameliorates small-for-size liver graft injury by attenuation of portal hypertension and down-regulation of Egr-1 pathway, Annals of Surgery. 2004, 240(1): 159-168. |
| Man K., Ng T.P., Lee K.W., Lo C.M., Sun K.W., Li X., Zhao Y., Ho J.W.Y. and Fan S.T., FTY720 attenuates hepatic ischemia-reperfusion injury in normal and cirrhotic livers, American Journal of Transplantation. 2005, 5(1): 40-49. |
| Man K., Ng T.P., Lo C.M., Sun K.W., Zhao Y., Ho J.W.Y., Lee K.W. and Fan S.T., Hepatic I/R injury on small liver remnant promotes liver tumor growth and metastasis - activation of cell invasion and migration pathways (Abstract), The 20th International Congress of the Transplantation Society, Vienna, Austria, 5-10 September 2004. |
| Man K., Ng T.P. and Fan S.T., Hepatic I/R injury on small liver remnant promotes liver tumour growth and metastasis - activation of cell invasion and migration pathway (Abstract), The 4th International Meeting on Hepatocellular Carcinoma: Eastern and Western Experiences, Hong Kong, 14-16 December 2004. |
| Man K., Ng T.P. and Fan S.T., Hepatic I/R injury on small liver remnant promotes liver tumour growth and metastasis - activation of cell invasion and mirgration pathway (Abstract), Asian Journal of Surgery. 2005, 28(Suppl 2): S83. |
| Man K., Xu A., Xu A., Zhao Y., Lo C.M., Ng T.P., Sun K.W. and Fan S.T., Rescue of small-for-size fatty liver grafts injury by FTY720 and adiponectin combination therapy (Abstract), The 20th International Congress of the Transplantation Society, Vienna, Austria, 5-10 September 2004. |
| Zhao Y., Man K., Lo C.M., Ng T.P., Li X.L., Sun K.W., Lee K.W., Dai X.W. and Fan S.T., Attenuation of small-for-size liver graft injury by FTY720: significance of cell-survival Akt signaling pathway, American Journal of Transplantation. 2004, 4(9): 1399-1407. |
| Researcher : Ng WM |
| List of Research Outputs |
| Ho W.K., Ng W.M. and Wei W.I., Laryngectomy for thyroid cancer involving the upper aerodigestive tract. , 6th International Conference on Head and Neck Cancer. . Washington, USA, 2004. |
| Ho W.K., Ng W.M., Wei W.I. and Yuen P.W., Ortner’s Syndrome: A radiological diagnosis. Poster presentation, 12th Annual Scientific Meeting, Hong Kong College of Radiologists. . Hong Kong, 2004. |
| Ng W.M. and Wei W.I., Elimination of palatal fistula after the mazillary swing procedure, Head & Neck. 2005, 27: 608-612. |
| Ng W.M., Koh A.J.H. and Ho W.K., Endoscopic sural nerve harvesting for facial nerve reconstruction How I do it. A targeted problem and its solution., Laryngoscope. 2005, 115: 925. |
| Wei W.I., Yuen P.W., Ng W.M., Ho W.K., Kwong D.L.W. and Sham J.S.T., Quantitative analysis of plasma cell-free epstein-barr virus DNA in nasopharyngeal carcinoma after salvage nasopharyngectomy: a prospective study, Head & Neck. 2004, 26: 878-883. |
| Researcher : Ngan ESW |
| Project Title: | Sonic hedgehog (Shh) signaling in the enteric neural crest cells |
| Investigator(s): | Ngan ESW, Sham MH, Lui VCH, Tam PKH |
| Department: | Surgery |
| Source(s) of Funding: | Seed Funding Programme for Basic Research |
| Start Date: | 01/2005 |
| Abstract: |
| Refer hard copy |
| List of Research Outputs |
| Law M.L., Ngan E.S.W., Lui V.C.H., Tam P.K.H. and Sham M.H., The role of Sox 10 on survival and proliferation of enteric neural crest stem cells, 3rd Annual Meeting of International Society for Stem Cell Research.. 2005. |
| Researcher : Patil NG |
| Project Title: | Audit of deaths and complications in surgical patients admitted to university surgical unit |
| Investigator(s): | Patil NG |
| Department: | Surgery |
| Source(s) of Funding: | Other Funding Scheme |
| Start Date: | 01/1992 |
| Abstract: |
| To assess: (1) quality and standard of care; (2) educational value; (3) reporting of complications; (4) incidence and prevalence of life threatening surgical conditions; (5) improvements in surgical techniques, investigation procedures, clinical practice and infrastructure. |
| Project Title: | Risk factors for inguinal hernia in adults: a case-control study |
| Investigator(s): | Patil NG, Lau H |
| Department: | Surgery |
| Source(s) of Funding: | Small Project Funding |
| Start Date: | 11/2002 |
| Abstract: |
| To evaluate and identify the risk factors for the development of inguinal hernia in adults. |
| Project Title: | Risk factors for hernia development in patients receiving continuous ambulatory peritoneal dialysis (CAPD) |
| Investigator(s): | Patil NG, Lau H |
| Department: | Surgery |
| Source(s) of Funding: | Small Project Funding |
| Start Date: | 11/2003 |
| Abstract: |
| To evaluate the incidence of and identify the risk factors for the development of hernia in patients who are undergoing CAPD. |
| List of Research Outputs |
| Lau H., Wong C., Chu K. and Patil N.G., Endoscopic totally extraperitoneal inguinal hernioplasty under general anesthesia, Endoscopic & Laparoscopic Surgeons of Asia Regional Meeting and 4th World Congress of Gasless Laparoscopic Surgery, Bali, Indonesia, 26 - 29 September 2004. |
| Lau H., Wong C., Chu K. and Patil N.G., Endoscopic totally extraperitoneal inguinal hernioplasty under spinal anesthesia, Journal of Laparoendoscopic & Advanced Surgical Techniques. 2005, 15(2): 121-124. |
| Lau H. and Patil N.G., Impact of previous appendectomy on the outcomes of endoscopic totally extraperitoneal inguinal hernioplasty, Surgical Laparoscopy, Endoscopy & Percutaneous Techniques. 2004, 14(5): 257-259. |
| Lau H., Patil N.G. and Yuen W.K., Outcomes of laparoscopic incisional hernia repair: A prospective evaluation, Surgical Practice. 2005, 9: 13-17. |
| Patil N.G., Assessment in problem-based learning: strength and weakness , 2nd Asia-Pacific Medical Education Conference, Singapore, 7-10 December 2004. |
| Patil N.G., Clinical PBL-making it work, 2nd Indonesian Medical Education Meeting and Expo, Bandung, Indonesia, 23-27 April 2005. |
| Patil N.G., Differential diagnosis and patient access to information, Academic Medicine. 2004, (online). |
| Patil N.G., Editor, Curriculum Reform: Foundation to Consolidation (Monograph), Institute of Medical and Health Sciences Education. 2004. |
| Patil N.G., Integration of basic and clinical disciplines in medical education, Frontier in Biomedical Research, Hong Kong, 3 December 2004. |
| Patil N.G., Intern assessment, Symposium and Workshop on "Assessment in Medical Education: Asian and International Perspectives", Hong Kong, 29-31 October 2004. |
| Patil N.G., International perspectives on national core curriculum: Hong Kong scenario, 2nd Indonesian Medical Education Meeting and Expo, Bandung, Indonesia, 23-27 April 2005. |
| Patil N.G., Invited Speaker, 2nd Asia-Pacific Medical Education Conference, Singapore, 7-10 December 2004. 2004. |
| Patil N.G., Invited Speaker, 2nd Indonesian Medical Education Meeting and Expo, Bandung, Indonesia, 23-27 April 2005. 2005. |
| Patil N.G., Invited Speaker, Frontier in Biomedical Research, The University of Hong Kong, 3 December 2004. 2004. |
| Patil N.G., Invited Speaker, Symposium and Workshop on "Assessment in Medical Education: Asian and International Perspectives", The University of Hong Kong, 29-31 October 2004. 2004. |
| Patil N.G., OSCE for practical skills, 2nd Indonesian Medical Education Meeting and Expo, Bandung, Indonesia, 23-27 April 2005. |
| Patil N.G., Presentations on behalf of Faculty of Medicine, The University of Hong Kong on 'Teaching of Anatomy' and 'Telehealth', Universitas 21 Health Sciences Annual Meeting of Deans/Heads, Queensland, Australia, 27 September-1 October 2004. 2004. |
| Patil N.G., Lee P.P.W. and Lo C.S., Student humour: the hidden message, Medical Education (The Clinical Teacher issue). 2005, 2(1): 5-9. |
| Patil N.G. and Ip M.S.M., The curriculum journey - where are we now?, Curriculum Reform: Foundation to Consolidation. The University of Hong Kong, 2004, 25-34. |
| Patil N.G., The postgraduate curriculum, A Practical Guide for Medical Teachers. U.K., Elsevier, 2005, 2nd edition: 28-37. |
| Patil N.G., U21 White Paper Professional Portability, Global e-Health: Identification of Opportunities of Technological Innovations to Address Issues of Global Health - U21 White Paper. 2004. |
| Patil N.G., University Teaching Fellowship for Excellence in Teaching, The University of Hong Kong. 2004. |
| Researcher : Poon RTP |
| Project Title: | Study of clinical significance of Endoglin (CD105) and vascular cell adhesion molecule-1 (VCAM-1) expression in hepatocellular carcinoma (HCC) |
| Investigator(s): | Poon RTP, Ho JWY |
| Department: | Surgery |
| Source(s) of Funding: | Small Project Funding |
| Start Date: | 11/2002 |
| Abstract: |
| To evaluate the clinical significance of the angiogenesis related factors, endoglin and VCAM-1, in terms of their prognostic implications in HCC patients after hepatectomy. |
| Project Title: | Prospective randomized trial of radiofrequency ablation versus hepatic resection for hepatocellular carcinoma <= 5 cm |
| Investigator(s): | Poon RTP, Fan ST |
| Department: | Surgery |
| Source(s) of Funding: | Competitive Earmarked Research Grants (CERG) |
| Start Date: | 12/2002 |
| Abstract: |
| The project attempts to compare the immediate and long-term outcomes between radiofrequency ablation (RFA) nad hepatic resection for patients with hepatocellular carcinoma (HCC) less than or equal to 5 cm. |
| Project Title: | Genetic analysis of epidermal growth factor receptor (EGFR) in hepatocellular carcinoma (HCC) and anti-cancer effect of the selective EGFR-tyrosine kinase inhibitor Iressa (ZD1839) in HCC cell lines |
| Investigator(s): | Poon RTP, Ho JWY |
| Department: | Surgery |
| Source(s) of Funding: | Small Project Funding |
| Start Date: | 11/2003 |
| Abstract: |
| To analyse the genetic expression of EGFR and its receptor family in HCC, and to evaluate the anti-cancer effect of EGFR tyrosine kinase inhibitor ZD1839 (Iressa) in HCC. |
| Project Title: | Effects of combined drug therapy using gleveec and FTY720 on angiogenesis and tumor growth in hepatocellular carcinoma |
| Investigator(s): | Poon RTP, Man K, Ho JWY |
| Department: | Surgery |
| Source(s) of Funding: | Small Project Funding |
| Start Date: | 11/2004 |
| Abstract: |
| To study the effect of combined drug therapy using Gleveec and FTY720 on tumor angiogenesis and tumor growth in hepatocellular carcinoma (HCC) using a nude mice model. |
| List of Research Outputs |
| Abdalla E.K., Pawlik T.M., Poon R.T.P., Zorzi D., Ikai I., Curley S.A., Nagorney D.M., Belghiti J., Ng I.O.L., Yamaoka Y., Lauwers G.Y. and Vauthey J.N., Critical appraisal of the clinical and pathological predictors of survival after resection of large hepatocellular carcinoma (Abstract), Asian Journal of Surgery. 2005, 28(Suppl): S87. |
| Abdalla E.K., Pawlik T.M., Poon R.T.P., Zorzi D., Ikai I., Curley S.A., Nagorney D.M., Belghiti J., Ng I.O.L., Yamaoka Y., Lauwers G.Y. and Vauthey J.N., Critical appraisal of the clinical and pathological predictors of survival after resection of large hepatocellular carcinoma (Abstract), The 4th International Meeting on Hepatocellular Carcinoma: Eastern and Western Experiences, Hong Kong, 14-16 December 2004. |
| Abdalla E.K., Pawlik T.M., Poon R.T.P., Sarmiento J.M., Ikai I., Curley S.A., Nagorney D.M., Belghiti J., Ng I.O.L., Yamaoka Y., Lauwers G.Y. and Vauthey J.N., Hepatitis serology defines tumor and liver disease characteristics but not prognosis after resection of hepatocellular carcinoma (Abstract), Asian Journal of Surgery. 2005, 28(Suppl): S81. |
| Abdalla E.K., Pawlik T.M., Poon R.T.P., Sarmiento J.M., Ikai I., Curley S.A., Nagorney D.M., Belghiti J., Ng I.O.L., Yamaoka Y., Lauwers G.Y. and Vauthey J.N., Hepatitis serology defines tumor and liver disease characteristics but not prognosis after resection of hepatocellular carcinoma (Abstract), The 4th International Meeting on Hepatocellular Carcinoma: Eastern and Western Experiences, Hong Kong, 14-16 December 2004. |
| Blazeby J.M., Currie E., Zee B.C., Chie W.C., Poon R.T.P. and Garden J.O., Development of a questionnaire module to supplement the EORTC QLQ-C30 to assess quality of life in patients with hepatocellular carcinoma, the EORTC QLQ-HCC18, European Journal of Cancer. 2004, 40(16): 2439-2444. |
| Chan S.Y., Poon R.T.P., Ng K.K.C., Liu C.L., Chan R.T. and Fan S.T., Long-term survival after intraluminal brachytherapy for inoperable hilar cholangiocarcinoma: a case report (Case Report), World Journal of Gastroenterology. 2005, 11(20): 3161-3164. |
| Chan S.Y., Poon R.T.P., Ng K.K.C., Lam C.M. and Fan S.T., Management of carcinoma of gallbladder: a single-institution expereince in 16 years (Abstract), Journal of Gastrointestinal Surgery. 2004, 8(7 Suppl): 68A. |
| Chan S.Y., Poon R.T.P., Ng K.K.C., Lam C.M. and Fan S.T., Management of carcinoma of gallbladder: a single-institution expereince in 16 years (Abstract), The 19th World Congress of Digestive Surgery, Yokohama, Japan, 8-11 December 2004. |
| Cheng P.N.M., Lo T., Leung T. and Poon R.T.P., Pegylated recombinant human hepatic arginase I (rhArg-peg 5,000 mw) inhibits human hepatocellular carcinoma in vitro and in vivo (Abstract), The 4th International Meeting on Hepatocellular Carcinoma: Eastern and Western Experiences, Hong Kong, 14-16 December 2004. |
| Cheng P.N.M., Leung T., Lo T. and Poon R.T.P., Remission of hepatocellular carcinoma with Arginine depletion induced by systemic release of endogenous hepatic arginase due to transheaptic embolization augmented by high-dose insulin: arginase as a potential drug candidate for hepatocellular carcinoma (Abstract), Asian Journal of Surgery. 2005, 28(Suppl): S85. |
| Cheng P.N.M., Leung T., Lo T. and Poon R.T.P., Remission of hepatocellular carcinoma with Arginine depletion induced by systemic release of endogenous hepatic arginase due to transheaptic embolization augmented by high-dose insulin: arginase as a potential drug candidate for hepatocellular carcinoma (Abstract), The 4th International Meeting on Hepatocellular Carcinoma: Eastern and Western Experiences, Hong Kong, 14-16 December 2004. |
| Cheung S.T. and Poon R.T.P., Cyclins and CDKs in liver diseases, In: Dufour J.F., Clavien P.A., Signaling Pathways in Liver Diseases. Heidelberg, Springer-Verlag, 2005, 325-331. |
| Chok K.S.H., Lam C.M., Li F.K., Ng K.K.C., Poon R.T.P., Lo C.M. and Fan S.T., Management of hepatocellular carcinoma in renal transplant recipients, Journal of Surgical Oncology. 2004, 87(3): 139-142. |
| Chok K.S.H., Ng K.C.K., Lam C.M., Ng K.K.C., Poon R.T.P. and Fan S.T., Selection portal vein clamping for radiofrequency ablation of hepatocellular carcinoma with portal vein invasion, Journal of Gastrointestinal Surgery. 2005, 9(4): 489-493. |
| Ho J.W.Y., Poon R.T.P., Tong C.S.W. and Fan S.T., Clinical significance of serum vascular cell adhesion molecule-1 levels in patients with hepatocellular carcinoma, World Journal of Gastroenterology. 2004, 10(14): 2014-2018. |
| Ho J.W.Y., Poon R.T.P., Sun K.W., Xue W.C. and Fan S.T., Clinicopathological and prognostic implications of endoglin (CD105) expression in hepatocellular carcinoma and its adjacent non-tumorous liver, World Journal of Gastroenterology. 2005, 11(2): 176-181. |
| Ho J.W.Y., Man K., Sun K.W., Poon R.T.P. and Fan S.T., Effective low dose combined-drug treatment using FTY720 and Gleeve in hepatocellular carcinoma (Abstract), The 6th Annual Scientific Meeting, Centre for the Study of Liver Disease, The University of Hong Kong, Hong Kong, 8 January 2005. |
| Ho J.W.Y., Man K., Sun K.W., Poon R.T.P. and Fan S.T., Effective low dose combined-drug treatment using FTY720 and Gleevec in hepatocellular carcinoma (Abstract), Asian Journal of Surgery. 2005, 28(Suppl 2): S82. |
| Ho J.W.Y., Man K., Sun K.W., Poon R.T.P. and Fan S.T., Effective low dose combined-drug treatment using FTY720 and Gleevec in hepatocellular carcinoma (Abstract), The 4th International Meeting on Hepatocellular Carcinoma: Eastern and Western Experiences, Hong Kong, 14-16 December 2004. |
| Lam C.M., Ng K.K.C., Poon R.T.P., Yuen H.F. and Fan S.T., Thoracoscopic RFA (Abstract), Asian Journal of Surgery. 2005, 28(Suppl 2): S77. |
| Lam C.M., Ng K.K.C., Poon R.T.P., Yuen H.F. and Fan S.T., Thoracoscopic RFA (Invited Lecture), The 4th International Meeting on Hepatocellular Carcinoma: Eastern and Western Experiences, Hong Kong, 14-16 December 2004. |
| Lang B.H.H., Poon R.T.P., Fan S.T. and Wong J., Outcomes of patients with hepatocellular carcinoma presenting with variceal bleeding, American Journal of Gastroenterology. 2004, 99(11): 2158-2165. |
| Lee K.W., Man K., Poon R.T.P., Lo C.M., Ng I.O.L. and Fan S.T., Disruption of p53-p21/WAF1 cell cycle pathway contributes to progression and worse clinical outcome of hepatocellular carcinoma, Oncology Reports. 2004, 12(1): 25-31. |
| Lee K.W., Man K., Ho J.W.Y., Wang X., Poon R.T.P., Sun K.W., Ng T.P., Ng I.O.L., Xu R. and Fan S.T., Significance of the Rac signaling pathway in HCC cell motility: implications for a new therapeutic target, Carcinogenesis. 2005, 26(3): 681-687. |
| Liu Y., Poon R.T.P. and Fan S.T., Antitumor activity of epidermal growth factor receptor tyrosine kinase Inhibitors in human hepatocellular carcinoma cell lines (Abstract), The 44th American Society For Cell Biology Annual Meeting, Washington D.C., U.S.A., December 4-8 2004. |
| Liu Y., Poon R.T.P., Shao W. and Fan S.T., Antitumour activity of epidermal growth factor receptor tyrosine kinase inhibitors in human hepatocellular carcinoma (Abstract), Asian Journal of Surgery. 2005, 28(Suppl 2): S90. |
| Liu Y., Poon R.T.P., Shao W. and Fan S.T., Antitumour activity of epidermal growth factor receptor tyrosine kinase inhibitors in human hepatocellular carcinoma (Abstract), The 4th International Meeting on Hepatocellular Carcinoma: Eastern and Western Experiences, Hong Kong, 14-16 December 2004. |
| Liu Y., Poon R.T.P. and Fan S.T., Blockage of vascular endothelial growth factor receptors by tyrosine kinase inhibitor PTK787/ZK222584 inhibits growth of hepatocellular carcinoma with metastatic potential by angiogenesis-independent effect (Abstract), The 96th Cancer Research Annual Meeting, Anaheim, California, U.S.A., 16-20 April 2005. |
| Liu Y., Poon R.T.P., Li Q., Kok T.W., Lau C.P.Y. and Fan S.T., Both antiangiogenesis- and angiogenesis-independent effects are responsible for hepatocellular carcinoma growth arrest by tyrosine kinase inhibitor PTK787/ZK222584, Cancer Research. 2005, 65(9): 3691-3699. |
| Liu Y., Poon R.T.P., Hughes J., Feng X., Yu W.C. and Fan S.T., Chemokine receptors support infiltration of lymphocyte subpopulations in human hepatocellular carcinoma, Clinical Immunology. 2005, 114(2): 174-182. |
| Liu Y., Poon R.T.P., Hughes J., Li Q.Y., Yu W.C. and Fan S.T., Desensitization of T lymphocyte function by CXCR3 ligands in human hepatocellular carcinoma, World Journal of Gastroenterology. 2005, 11(2): 164-170. |
| Ng K.K.C., Poon R.T.P., Lam C.M., Yuen J., Tso W.K. and Fan S.T., Comparison of radiofrequency ablation and transarterial chemoembolization for unresectable hepatocellular carcinoma (Abstract), Journal of Gastrointestinal Surgery. 2004, 8(7 Suppl): 325A. |
| Ng K.K.C., Poon R.T.P., Lam C.M., Yuen J., Tso W.K. and Fan S.T., Comparison of radiofrequency ablation and transarterial chemoembolization for unresectable hepatocellular carcinoma (Poster Presentation), The 19th World Congress of Digestive Surgery, Yokohama, Japan, 8-11 December 2004. |
| Ng K.K.C., Lam C.M., Poon R.T.P., Shek T.W.H., To J.Y.T., Wo Y.H., Ho D.W.Y. and Fan S.T., Comparison of systemic responses of radiofrequency ablation, cryotherapy, and surgical resection in a porcine liver model, Annals of Surgical Oncology. 2004, 11(7): 650-657. |
| Ng K.K.C., Poon R.T.P., Lam C.M. and Fan S.T., Initial experience of radiofrequency ablation for ruptured hepatocellular carcinoma (Abstract), Asian Journal of Surgery. 2005, 28(Suppl 2): S93. |
| Ng K.K.C., Poon R.T.P., Lam C.M. and Fan S.T., Initial experience of radiofrequency ablation for ruptured hepatocellular carcinoma (Abstract), Journal of Gastrointestinal Surgery. 2004, 8(7 Suppl): 151A. |
| Ng K.K.C., Poon R.T.P., Lam C.M. and Fan S.T., Initial experience of radiofrequency ablation for ruptured hepatocellular carcinoma (Abstract), The 19th World Congress of Digestive Surgery, Yokohama, Japan, 8-11 December 2004. |
| Ng K.K.C., Poon R.T.P., Lam C.M. and Fan S.T., Initial experience of radiofrequency ablation for ruptured hepatocellular carcinoma (Abstract), The 4th International Meeting on Hepatocellular Carcinoma: Eastern and Western Experiences, Hong Kong, 14-16 December 2004. |
| Ng K.K.C., Vauthey J.N., Pawlik T.M., Lauwers G.Y., Regimbeau J.M., Belghiti J., Ikai I., Yamaoka Y., Curley S.A., Nagorney D.M., Ng I.O.L., Fan S.T. and Poon R.T.P., Is hepatic resection for large or multinodular hepatocellular carcinoma justified? Results from a multi-institutional database (Abstract), Asian Journal of Surgery. 2005, 28(Suppl 2). |
| Ng K.K.C., Vauthey J.N., Pawlik T.M., Lauwers G.Y., Regimbeau J.M., Belghiti J., Ikai I., Yamaoka Y., Curley S.A., Nagorney D.M., Ng I.O.L., Fan S.T. and Poon R.T.P., Is hepatic resection for large or multinodular hepatocellular carcinoma justified? Results from a multi-institutional database (Abstract), The 4th International Meeting on Hepatocellular Carcinoma: Eastern and Western Experiences, Hong Kong, 14-16 December 2004. |
| Ng K.K.C., Vauthey J.N., Pawlik T.M., Lauwers G.Y., Regimbeau J.M., Belghiti J., Ikai I., Yamaoka Y., Curley S.A., Nagorney D.M., Ng I.O.L., Fan S.T. and Poon R.T.P., Is hepatic resection for large or multinodular hepatocellular carcinoma justified? Results from a multi-institutional database, Annals of Surgical Oncology. 2005, 12(5): 364-373. |
| Ng K.K.C., Lam C.M., Poon R.T.P., Shek T.W.H., Ho D.W.Y. and Fan S.T., Maximal host tolerance to large-volume hepatic radiofrequency ablation in a rat model (Abstract), Journal of Gastrointestinal Surgery. 2004, 8( 7 Suppl): 114A. |
| Ng K.K.C., Lam C.M., Poon R.T.P., Shek T.W.H., Ho D.W.Y. and Fan S.T., Maximal host tolerance to large-volume hepatic radiofrequency ablation in a rat model (Abstract), The 19th World Congress of Digestive Surgery, Yokohama, Japan, 8-11 December 2004. |
| Ng K.K.C., Lam C.M., Poon R.T.P., Shek T.W.H., Yu W.C., To J.Y.T., Wo Y.H., Lau C.P.Y., Tang T.C.M., Ho D.W.Y. and Fan S.T., Porcine liver: morphological characteristics and cell viability at experimental radiofrequency ablation with internally cooled electrodes, Radiology. 2005, 235(2): 478-486. |
| Ng K.K.C., Poon R.T.P., Lam C.M., Yuen J., Tso W.K. and Fan S.T., Safety and efficacy of radiofrequency ablation for perivascular hepatocellular carcinoma without hepatic inflow occlusion (Abstract), The 6th Annual Scientific Meeting, Centre for the Study of Liver Disease, The University of Hong Kong, Hong Kong, 8 January 2005. |
| Ng K.K.C., Poon R.T.P., Lam C.M., Yuen J., Tso W.K. and Fan S.T., Safety and efficacy of radiofrequency ablation for perivascular hepatocellular carcinoma without inflow occlusion (Abstract), Journal of Gastrointestinal Surgery. 2004, 8(7 Suppl): 115A. |
| Ng K.K.C., Poon R.T.P., Lam C.M., Yuen J., Tso W.K. and Fan S.T., Safety and efficacy of radiofrequency ablation for perivascular hepatocellular carcinoma without inflow occlusion (Abstract), The 19th World Congress of Digestive Surgery, Yokohama, Japan, 8-11 December 2004. |
| Pang R.W.C., Lee K.W., Man K., Poon R.T.P., Fan S.T., Kwong Y.L. and Tse E.W.C., RNAi-mediated silencing of PIN1 inhibits HCC tumorigenicity (Abstract), The 96th Annual Meeting of the American Association for Cancer Research, Anaheim, California, U.S.A., 16-20 April 2005. |
| Pang W.C., Lee K.W., Man K., Poon R.T.P., Fan S.T., Kwong Y.L. and Tse E.W.C., Inhibition of hepatocellular carcinoma tumourigenicity by RNAi-mediated PIN1 silencing (Abstract), The 6th Annual Scientific Meeting, Centre for the Study of Liver Disease, The University of Hong Kong, Hong Kong, 8 January 2005. |
| Pang W.C., Lee K.W., Man K., Poon R.T.P., Fan S.T., Kwong Y.L. and Tse E.W.C., RNAi-mediated PIN1 silencing inhibits HCC trumourigenicity (Abstract), Asian Journal of Surgery. 2005, 28(Suppl 2): S84. |
| Pang W.C., Lee K.W., Man K., Poon R.T.P., Fan S.T., Kwong Y.L. and Tse E.W.C., RNAi-mediated PIN1 silencing inhibits HCC tumourigenicity (Abstract), The 4th International Meeting on Hepatocellular Carcinoma: Eastern and Western Experiences, Hong Kong, 14-16 December 2004. |
| Pang W.C., Lee K.W., Man K., Poon R.T.P., Fan S.T., Kwong Y.L. and Tse E.W.C., RNAi-mediated silencing of PIN1 inhibits HCC tumorigenicity, The 11th Hong Kong International Cancer Congress, Hong Kong, 10-12 November, 2004. |
| Pawlik T.M., Poon R.T.P., Abdalla E.K., Zorzi D., Ikai I., Curley S.A., Nagorney D.M., Belghiti J., Ng I.O.L., Yamaoka Y., Lauwers G.Y. and Vauthey J.N., Critical appraisal of the clinical and pathologic predictors of survival after resection of large hepatocellular carcinoma, Archives of Surgery. 2005, 140(5): 450-457. |
| Pawlik T.M., Poon R.T.P., Abdalla E.K., Zorzi D., Ikai I., Curley S.A., Nagorney D.M., Belghiti J., Ng I.O.L., Yamaoka Y., Lauwers G.Y. and Vauthey J.N., Critical appraisal of the clinical and pathological predictors of survival after resection of large hepatocellular carcinoma (Abstract), The 112th Scientific Session of the Western Surgical Association; Las Vegas, U.S.A., 9 November, 2004. |
| Pawlik T.M., Poon R.T.P., Abdalla E.K., Ikai I., Nagorney D.M., Belghiti J., Kianmanesh R., Ng I.O.L., Curley S.A., Yamaoka Y., Lauwers G.Y. and Vauthey J.N., Hepatectomy for hepatocellular carcinoma with major portal or hepatic vein invasion: results of a multicenter study, Surgery. 2005, 137(4): 403-410. |
| Pawlik T.M., Poon R.T.P., Abdalla E.K., Sarmiento J.M., Ikai I., Curley S.A., Nagorney D.M., Belghiti J., Ng I.O.L., Yamaoka Y., Lauwers G.Y. and Vauthey J.N., Hepatitis serology predicts tumor and liver disease characteristics but not prognosis after resection of hepatocellular carcinoma, Journal of Gastrointestinal Surgery. 2004, 9(7): 794-805. |
| Poon R.T.P., Ng K.K.C. and Fan S.T., A phase I/II study of treatment of inoperable hepatocellular carcinoma using transarterial doxorubicin eluting bead embolisation (Invited Lecture), The 6th Annual Scientific Meeting, Centre for the Study of Liver Disease, The University of Hong Kong, Hong Kong, 8 January 2005. 2005. |
| Poon R.T.P., Adult to adult live liver transplantation (State-of-the-Art Lecture), International Forum on Liver Transplantation and Artificial Liver, Nanjing, China, 29 November 2004. 2004. |
| Poon R.T.P., Aggressive management of recurrent HCC: from local ablation to salvage transplantation (Invited Lecture), The 4th International Meeting on Hepatocellular Carcinoma: Eastern and Western Experiences, Hong Kong, 14-16 December 2004. 2004. |
| Poon R.T.P., Aggressive management of recurrent hepatocellular carcinoma: from local ablation to salvage transplantation (Invited Lecture), The 8th Congress of Asian Hepatobiliary and Pancreatic Surgery Society, Manila, Philippines, 10 February 2005. 2005. |
| Poon R.T.P., Anti-angiogenesis therapy for HCC (Invited Lecture), "Cancer Therapeutic" Symposium, "Genomics, Proteomics and Therapeutics in Cancer Research" Conference, Faculty of Medicine, The University of Hong Kong, 20-21 October 2004. 2004. |
| Poon R.T.P., Anti-angiogenesis therapy for hepatocellular carcinoma (Invited Lecture), The 11th Hong Kong International Cancer Congress, Hong Kong, 10-12 November 2004. 2004. |
| Poon R.T.P., Antiangiogenic therapy (Invited Lecture), The 4th International Meeting on Hepatocellular Carcinoma: Eastern and Western Experiences, Hong Kong, 14-16 December 2004. 2004. |
| Poon R.T.P. and Fan S.T., Assessment of hepatic reserve for indication of hepatic resection: how I do it, Journal of Hepato-Biliary-Pancreatic Surgery. 2005, 12(1): 31-37. |
| Poon R.T.P., Associate Editor (July 2003 - present), Cancer Reviews: Asia-Pacific. 2005. |
| Poon R.T.P., Yang Z., Liu Y., Ho D.W.Y., Lau C.K. and Fan S.T., Blockade of vascular endothelial growth factor (VEGF) receptor enhances the therapeutic efficacy and chemotherapy in hepatocellular carcinoma (Abstract), The 96th Annual Meeting of the American Association for Cancer Research, Anaheim, California, U.S.A., 16-20 April 2005. |
| Poon R.T.P., Chairman - Cancer therapeutic symposium, "Genomics, Proteomics and Therapeutics in Cancer Research" Conference. Faculty of Medicine, The University of Hong Kong, Hong Kong, 20-21 October 2004 . 2004. |
| Poon R.T.P., Chairman - Debate session "Large hepatocellular carcinoma with vascular invasion: to treat or not to treat?", The 4th International Meeting on Hepatocellular Carcinoma: Eastern and Western Experiences, Hong Kong, 14-16 December 2004. 2004. |
| Poon R.T.P., Chairman - Free paper session "Perioperative management of liver tumor", The 19th World Congress of Digestive Surgery, Yokohama, Japan, 8-11 December 2004. 2004. |
| Poon R.T.P., Chairman - Genomics and surgical oncology symposium, Hong Kong Surgical Forum, Hong Kong, 9 July 2004. 2004. |
| Poon R.T.P., Chairman - Lecture "Biological principles of anti-VEGF therapy", The 11th Hong Kong International Cancer Congress, Hong Kong, 10-12 November 2004. 2004. |
| Poon R.T.P., Chairman - Symposium "Novel therapies for hepatocellular carcinoma", The 4th International Meeting on Hepatocellular Carcinoma: Eastern and Western Experiences, Hong Kong, 14-16 December 2004. 2004. |
| Poon R.T.P., Chairman - Symposium on applied physiology in surgery, Hong Kong Surgical Forum, Hong Kong, 15 January 2005. 2005. |
| Poon R.T.P., Chairman - Symposium on cancer, Frontiers in Biomedical Research, The University of Hong Kong, Hong Kong, 3 December 2004. 2004. |
| Poon R.T.P., Chairman of Organizing Committee, The 4th International Meeting on Hepatocellular Carcinoma: Eastern and Western Experiences, Hong Kong, 14-16 December 2004. 2004. |
| Poon R.T.P., Clinical implications of angiogenesis in hepatocellular carcinoma (Visiting Professor Lecture), Chiba University, Chiba, Japan, 3 June 2005. 2005. |
| Poon R.T.P., Clinical implications of angiogenesis in hepatocellular carcinoma (Visiting Professor Lecture), Third Military Medical University of China, Southwest Hospital of Hepatobiliary Surgery, Chongqing, China, 21-22 March 2005. 2005. |
| Poon R.T.P., Clinical implications of cancer angiogenesis (Visiting Professor Lecture), The University of Belgrade, Belgrade, Yugoslavia, 9 May 2005. 2005. |
| Poon R.T.P., Current issues of liver transplantation for hepatocellular carcinoma (Invited Lecture), The 8th Congress of Asian Hepatobiliary and Pancreatic Surgery Society, Manila, Philippines, 10 February 2005. 2005. |
| Poon R.T.P., Current management of hepatocellular carcinoma (Sate-of-the-Art Lecture), Conference on Liver Transplantation of European Association of Hepatobiliary Pancreatic Association, Belgrade, Yugoslavia, 10 May 2005. 2005. |
| Poon R.T.P., Current surgical management of hepatocellular carcinoma (Visiting Professor Lecture), Chiba University, Chiba, Japan, 3 June 2005. 2005. |
| Poon R.T.P., Editor (January 2001 - December 2004), Hong Kong Medical Journal. 2004. |
| Poon R.T.P., Epidemiology of hepatocellular carcinoma (Invited Lecture), The 4th International Meeting on Hepatocellular Carcinoma: Eastern and Western Experiences, Hong Kong, 14-16 December 2004. 2004. |
| Poon R.T.P., Evaluation of a novel intra-arterial delivery system for the treatment of hepatocellular carcinoma (Invited Lecture), The 1st Interventional Congress of Comprehensive Diagnosis and Interventional Therapy of Hepatocellular Carcinoma, Shanghai, China, 25-26 June 2005. 2005. |
| Poon R.T.P., Hepatic resection using TissueLink Dissecting Sealer (Invited Lecture), Liver Resection Workshop, The Chinese University of Hong Kong, Hong Kong, 17 December 2004. 2004. |
| Poon R.T.P., How to improve long-term survival after resection of hepatocellular carcinoma? (Visiting Professor Lecture), Third Military Medical University of China, Southwest Hospital of Hepatobiliary Surgery, Chongqing, China, 21-22 March 2005. 2005. |
| Poon R.T.P., Impact of RFA in an experienced surgical centre (Invited Lecture), The 4th International Conference on Image-Guided Ablation Therapies of Neoplastic Diseases, Milan, Italy, 14-16 October 2004. 2004. |
| Poon R.T.P., Impact of radiofrequency ablation on management of liver tumors (Invited Lecture), The 8th Congress of Asian Hepatobiliary and Pancreatic Surgery Society, Manila, Philippines, 10 February 2005. 2005. |
| Poon R.T.P., Fan S.T., Lo C.M., Liu C.L., Lam C.M., Yuen W.K., Yeung C. and Wong J., Improving perioperative outcome expands the role of hepatectomy in management of benign and malignant hepatobiliary diseases: analysis of 1222 consecutive patients from a prospective database, Annals of Surgery. 2004, 240(4): 698-708. |
| Poon R.T.P. and Fan S.T., Is primary resection and salvage transplantation for hepatocellular carcinoma a reasonable strategy? (Letter to the Editor), Annals of Surgery. 2004, 240(5): 925-928. |
| Poon R.T.P., Fan S.T. and Wong J., Liver resection using a saline-linked radiofrequency dissecting sealer for transection of the liver, Journal of the American College of Surgeons. 2005, 200(2): 308-313. |
| Poon R.T.P., Liver transplantation for hepatocellular cancer (Invited Lecture), The 2nd Multidisciplinary Management of Gastrointestinal Malignancies (MD Anderson Cancer Center), Hawaii, U.S.A.,13-17 November 2004. 2004. |
| Poon R.T.P., Liver transplantation for hepatocellular carcinoma (Invited Lecture), International Forum on Liver Transplantation and Artificial Liver, Nanjing, China, 29 November 2004. 2004. |
| Poon R.T.P., Looregional therapy for hepatocellular carcinoma: from bench to clinic (Invited Lecture), Innovation in Cancer Therapies: First International Conference. London, United Kingdom, 1 May 2005. 2005. |
| Poon R.T.P., Member of Editorial Board (March 2003 - present), Cancer Therapy. 2005. |
| Poon R.T.P., Member of Editorial Board (November 2002 - present), 消化外科, 2005. |
| Poon R.T.P., Member of Organizing Committee, Frontiers in Biomedical Research, The University of Hong Kong, Hong Kong, 3 December 2004. 2004. |
| Poon R.T.P., New horizons in the management of hepatocellular carcinoma (State-of-the-Art Lecture), Surgical Symposium of the Hong Kong Sanatorium and Hospital, Hong Kong, 5 November 2004. 2004. |
| Poon R.T.P., Optimizing long-term survival after resection of hepatocellular carcinoma (Invited Lecture), The 8th Congress of Asian Hepatobiliary and Pancreatic Surgery Society, Manila, Philippines, 10 February 2005. 2005. |
| Poon R.T.P., Prognostic impact of diabetes mellitus on patients with hepatocellular carcinoma (Editorial), American Journal of Gastroenterology. 2004, 99: 1488-1489. |
| Poon R.T.P., Ho J.W.Y., Tong C.S.W., Lau C.P.Y., Ng I.O.L. and Fan S.T., Prognostic significance of serum vascular endothelial growth factor and endostatin in patients with hepatocellular carcinoma, British Journal of Surgery. 2004, 91(10): 1354-1360. |
| Poon R.T.P., Randomized trial in progress: RFA vs surgery for small HCC (Invited Lecture), The 4th International Conference on Image-Guided Ablation Therapies of Neoplastic Diseases, Milan, Italy, 14-16 October 2004. 2004. |
| Poon R.T.P., Recent advances in techniques of liver resection, Surgical Technology International. 2004, 13: 71-77. |
| Poon R.T.P., Role of nutrient therapy for patients with hepatocellular carcinoma (Plenary Lecture), The 41st Annual Meeting of the Japan Study Group of Liver Cancer, Chiba, Japan, 2-3 June 2005. 2005. |
| Poon R.T.P., Transarterial chemoembolization for hepatocellular carcinoma using drug eluting microspheres (Invited Lecture), Annual Congress of Cardiovascular and Interventional Radiological Society of Europe, Barcelona, Spain, 25-29 September 2004. 2004. |
| Poon R.T.P., Transarterial chemoembolization for liver cancer (Invited Lecture), The 19th World Congress of International Society of Digestive Surgery, Yokohama, Japan, 8-11 December 2004. 2004. |
| Poon R.T.P., Treatment of HCC: what Level of consensus can be achieved? (Invited Lecture), The 4th International Conference on Image-Guided Ablation Therapies of Neoplastic Diseases, Milan, Italy, 14-16 October 2004. 2004. |
| Poon R.T.P., Vice-Chairman of Organizing Committee, The 11th Hong Kong International Cancer Congress, Hong Kong, 10-12 November 2004. 2004. |
| Poon R.T.P., Xia F. and Fan S.T., 原發性肝癌的治療原則, In: 芮靜安, 現代癌診斷治療學, 清華大學出版社, 2004, 205-220. |
| Sabherwal Y., Rothman V., Poon R.T.P. and Tuszynski G., Clinical significance of serum angiocidin levels in hepatocellular carcinoma (Abstract), The 96th Annual Meeting of the American Association for Cancer Research, Anaheim, California, U.S.A., 16-20 April 2005. |
| Tang T.C.M., Poon R.T.P., Guan X.Y. and Fan S.T., Celecoxib suppresses HCC development via the cell cycle arrest pathway (Poster Presentation), The 96th Annual Meeting of the American Association for Cancer Research, Anaheim, California, U.S.A., 16-20 April 2005. |
| Tang T.C.M., Poon R.T.P., Lau C.P.Y., Xie D. and Fan S.T., Cytosolic cyclooxygenase-2 levels correlate with cytosolic vascular endothelial growth factor levels and tumor invasiveness in human hepatocellular carcinoma (Abstract), The 1st Annual Conference for the Organisation for Oncology and Translational Research, Hong Kong, 15-16 October 2004. |
| Tang T.C.M., Poon R.T.P., Guan X.Y. and Fan S.T., The significance of cyclooxygenase-2 in hepatocellular carcinoma (Abstract), The 6th Annual Scientific Meeting, Centre for the Study of Liver Disease, The University of Hong Kong, Hong Kong, 8 January 2005. |
| Tang T.C.M., Poon R.T.P., Lau C.P.Y., Xie D. and Fan S.T., Tumor cyclooxygenase-2 levels correlate with tumor invasiveness in human hepatocellular carcinoma, World Journal of Gastroenterology. 2005, 11(13): 1896-1902. |
| To Y.F., Ip E.W.K., Chong W.P., Yuen M.F., Poon R.T.P., Wong W.H.S., Lai C.L. and Lau Y.L., Mannose Binding Lectin in Chronic Hepatitis B Virus Infection, Ruby Jubilee Scientific Meeting, HK, 24-26 Sepember 2004. Abstract in Hong Kong Journal of Paediatrics (new series). 2004, 9 (suppl): 47. |
| Tsang J., Ng K.K.C., Tung H., Yuen J., Poon R.T.P. and Lam C.M., Comparison of percutaneous RFA and hepatic resection for recurrent HCC (Abstract), The 12th Annual Scientific Meeting of Hong Kong College of Radiologists, Hong Kong, 30-31 October 2004. |
| Wong S.M.Y., Ng K.K.C., Poon R.T.P., Lam C.M., Yuen J., Tso W.K. and Fan S.T., Comparison of radiofrequency ablation and transarterial chemoembolisation for unresectable hepatocellular carcinoma (Abstract), Asian Journal of Surgery. 2005, 28(Suppl 2): S105. |
| Wong S.M.Y., Ng K.K.C., Poon R.T.P., Lam C.M., Yuen J., Tso W.K. and Fan S.T., Comparison of radiofrequency ablation and transarterial chemoembolisation for unresectable hepatocellular carcinoma (Abstract), The 4th International Meeting on Hepatocellular Carcinoma: Eastern and Western Experiences, Hong Kong, 14-16 December 2004. |
| Xu Y., Sun H.C., Liu Y., Poon R.T.P. and Tang Z.Y., A specific peptide to human hepatocellular carcinoma vasculature selected by modified in vitro phage display (Abstract), Asian Journal of Surgery. 2005, 28(Suppl): S91. |
| Xu Y., Sun H.C., Liu Y., Poon R.T.P. and Tang Z.Y., A specific peptide to human hepatocellular carcinoma vasculature selected by modified in vitro phage display (Abstract), The 4th International Meeting on Hepatocellular Carcinoma: Eastern and Western Experiences, Hong Kong, 14-16 December 2004. |
| Yang Z., Ho D.W.Y., Lam C.T., Luk J.M.C., Lum C.T., Yu W.C., Poon R.T.P. and Fan S.T., Identification of brain-derived neurotrophic factor (BDNF) as a potential therapeutic target in hepatocellular carcinoma (Abstract), The 4th International Meeting on Hepatocellular Carcinoma: Eastern and Western Experiences, Hong Kong, 14-16 December 2004. |
| Yang Z., Ho D.W.Y., Lam C.T., Luk J.M.C., Yu W.C., Lo C.M., Poon R.T.P. and Fan S.T., Identification of brain-derived neurotrophic factor (BDNF) in hepatocellular carcinoma - from animal study to clinical management (Abstract), The 6th Annual Scientific Meeting, Centre for the Study of Liver Disease, The University of Hong Kong, Hong Kong, 8 January 2005. |
| Yang Z., Ho D.W.Y., Lam C.T., Luk J.M.C., Lum C.T., Yu W.C., Poon R.T.P. and Fan S.T., Identification of brain-derived neurotrophic factor as a novel functional protein in hepatocellular carcinoma, Cancer Research. 2005, 65(1): 219-225. |
| Yang Z., Ho D.W.Y., Lam C.T., Luk J.M.C., Poon R.T.P. and Fan S.T., The potential role of allograft inflammatory factor 1 (AIF-1) in macrophage activation in small-for-size liver transplantation, The 20th International Congress of the Transplantation Society, Vienna, Austria, 5-10 September 2004. |
| Yang Z., Poon R.T.P., To J.Y.T., Ho D.W.Y. and Fan S.T., The potential role of hypoxia inducible factor 1a in tumor progression after hypoxia and chemotherapy in hepatocellular carcinoma, Cancer Research. 2004, 64(15): 5496-5503. |
| Yang Z., Poon R.T.P., Luo Y., Cheung C.K.Y., Ho D.W.Y., Lo C.M. and Fan S.T., Up-regulation of vascualr endothelial growth factor (VEGF) in small-for-size liver grafts enhances macrophage activities through VEGF receptor 2-dependent pathway, Journal of Immunology. 2004, 173(4): 2507-2515. |
| Yong J.L., Lam C.M., Chan O.O., Poon R.T.P., Liu C.L., Lo C.M. and Fan S.T., Better survival in female patients with hepatocellular carcinoma (Abstract), Asian Journal of Surgery. 2005, 28(Suppl 2): S94. |
| Yong J.L., Lam C.M., Chan O.O., Poon R.T.P., Liu C.L., Lo C.M. and Fan S.T., Better survival in female patients with hepatocellular carcinoma (Abstract), The 4th International Meeting on Hepatocellular Carcinoma: Eastern and Western Experiences, Hong Kong, 14-16 December 2004. |
| Researcher : Ren Y |
| Project Title: | Lipopolysaccharide (LPS) potentiates phagocyte clearance of neutrophils undergoing apoptosis |
| Investigator(s): | Ren Y, Savill J. |
| Department: | Surgery |
| Source(s) of Funding: | Competitive Earmarked Research Grants (CERG) |
| Start Date: | 01/2003 |
| Completion Date: | 12/2004 |
| Abstract: |
| The project aims at dissecting the role of lipopolysaccharide (LPS) in modulating phagocytosis of apoptotic neutrophils (PMN) by macophage. |
| Project Title: | Proteomics computational analysis of Severe Acute Respiratory Syndrome |
| Investigator(s): | Ren Y, Tam PKH, Peiris JSM, He Q, Fan J.Q. |
| Department: | Surgery |
| Source(s) of Funding: | VCO SARS Research Fund |
| Start Date: | 07/2003 |
| Abstract: |
| To investigate by using proteomics approach, combining Western blotting and ELISA: (a) identification of specific pattern in serum for the diagnosis and prognosis, (b) detection of immune-relevant proteins in SARS, (c) detection of proteins in different stages of SARS patients, (d) proteome analysis of SCV (proteome maps), (e) detection of expression patterns in virus infected cells. |
| Project Title: | Combined laser capture microdissection and proteomic approaches for the identification of invasiveness and metastasis-specific protein markers in esophageal squamous cell carcinoma |
| Investigator(s): | Ren Y, Law SYK, Wong J |
| Department: | Surgery |
| Source(s) of Funding: | Seed Funding Programme for Basic Research |
| Start Date: | 02/2004 |
| Completion Date: | 01/2005 |
| Abstract: |
| To apply LCM to procure esophageal carcinoma cells from primary, invasive and metastatic tumor tissues, respectively, and to define invasive and metastatic - specific and normal-specific protein markers by proteomics. Such studies would greatly facilitate our understanding of invasiveness and metastatic properties of ESCC. |
| List of Research Outputs |
| He Q., Zhu R., Ren Y., Tam P.K.H. and Chiu J., Serological protein profiling of neuroblastoma by proteinchip SELDI-TOF technology, Journal of Cellular Biochemistry. 2005, 95: 165-172. |
| Lau W.C.S., Yeung J.S.L., Chan W.K. and Ren Y., Diminished macrophage (Mac) clearance of apoptotic polymorphonuclear cells (PMN) in patients with rheumatoid arthritis (RA), 11th APLAR Bi-annual Congress, Jeju, Korea 11-16 Septemer 2004. |
| Ren Y., Chen Y., Li W., Jiang G., Liu Q., Chan H.M. and Tam P.K.H., Anti-sense gene therapy for human neuroblastoma by targeting disruption of macrophage migration inhibitory factor (MIF): in vitro and nude mice studies, 51st Annual International Congress of British Association of Paediatric Surgeons, Oxford, U.K. 27-30 July 2004. |
| Ren Y., Li W., Liu Q., Yu W.Y., Sun R.W.Y., Che C.M. and Tam P.K.H., Gold (III) porphyrines: a novel chemotherapeutic agent for human neuroblastoma, 51st Annual International Congress of British Association of Paediatric Surgeons, Oxford, U.K. 27-30 July. 2004. |
| Ren Y., He Q., Fan J.Q., Jones B., Zhou Y., Xie Y., Cheung C.Y., Wu A.Y.Y., Chiu J., Peiris J.S.M. and Tam P.K.H., The use of proteomics in the discovery of serum biomarkers from patients with severe acute respiratory syndrome, Proteomics. 2004, 4: 3477-3484. |
| Ren Y., Lin C.L., Li Z., Chen X.Y., Huang X., Lui V.C.H., Nicholls J.M., Lan H.Y. and Tam P.K.H., Up-regulation of macrophage migration inhibitory factor in infants with acute neonatal necrotizing enterocolitis, Histopathology. 2005, 46(6): 659-667. |
| Researcher : Shao W |
| List of Research Outputs |
| Liu Y., Poon R.T.P., Shao W. and Fan S.T., Antitumour activity of epidermal growth factor receptor tyrosine kinase inhibitors in human hepatocellular carcinoma (Abstract), Asian Journal of Surgery. 2005, 28(Suppl 2): S90. |
| Researcher : Shi X |
| List of Research Outputs |
| Yi C., Li Z., Yuan K., Qu X., Chen J., Wang G., Zhang H., Luo H., Zhu L., Jiang P., Chen L., Shen Y., Luo M., Zuo G., Hu J., Duan D., Nie Y., Shi X., Wang W., Han Y., Li T., Liu Y., Ding M., Deng H. and Xu X., Small molecules blocking the entry of SARS-Co V into host, Journal of Virology. 2004, 78(2)): 11334-11339. |
| Researcher : Shum KY |
| List of Research Outputs |
| Shum K.Y., Molecular cloning and characterization of a novel germ cell-specific gene, VAD1.3, in spermatogenesis, Thesis, Master of Philiosophy, The University of Hong Kong. 2004. |
| Researcher : Su YCF |
| Project Title: | A reassessment of the taxonomic relationships of Petalolophus and Pseuduvaria (Annonaceae) |
| Investigator(s): | Su YCF, Saunders RMK |
| Department: | Ecology and Biodiversity |
| Source(s) of Funding: | Small Project Funding |
| Start Date: | 11/2004 |
| Abstract: |
| To reassess the taxonomic status of Petalolophus and Pseuduvaria, which are believed to be phylogentically close. |
| List of Research Outputs |
| Luk J.M.C., Lee C.K.F., Su Y.C.F., Lam C.T., Hu M.Y., He Q., Lau G., Wong W.S. and Fan S.T., Proteomic identification of Ku70/Ku80 autoantigen recognized by monoclonal antibody against hepatocellular carcinoma (Abstract), HUPO 3rd Annual World Congress, Beijing, China, 25-27 October 2004. |
| Luk J.M.C., Su Y.C.F., Lam C.T., Lee C.K.F., Hu M.Y., He Q., Lau G., Wong F.W.S. and Fan S.T., Proteomic identification of Ku70/Ku80 autoantigen recognized by monoclonal antibody against hepatocellular carcinoma, Proteomics. 2005, 5(7): 1980-1986. |
| Researcher : Sun KW |
| List of Research Outputs |
| Ho J.W.Y., Poon R.T.P., Sun K.W., Xue W.C. and Fan S.T., Clinicopathological and prognostic implications of endoglin (CD105) expression in hepatocellular carcinoma and its adjacent non-tumorous liver, World Journal of Gastroenterology. 2005, 11(2): 176-181. |
| Ho J.W.Y., Man K., Sun K.W., Poon R.T.P. and Fan S.T., Effective low dose combined-drug treatment using FTY720 and Gleeve in hepatocellular carcinoma (Abstract), The 6th Annual Scientific Meeting, Centre for the Study of Liver Disease, The University of Hong Kong, Hong Kong, 8 January 2005. |
| Ho J.W.Y., Man K., Sun K.W., Poon R.T.P. and Fan S.T., Effective low dose combined-drug treatment using FTY720 and Gleevec in hepatocellular carcinoma (Abstract), Asian Journal of Surgery. 2005, 28(Suppl 2): S82. |
| Ho J.W.Y., Man K., Sun K.W., Poon R.T.P. and Fan S.T., Effective low dose combined-drug treatment using FTY720 and Gleevec in hepatocellular carcinoma (Abstract), The 4th International Meeting on Hepatocellular Carcinoma: Eastern and Western Experiences, Hong Kong, 14-16 December 2004. |
| Lee K.W., Man K., Ho J.W.Y., Sun K.W., Ng T.P., Wang X., Wong Y.C., Ng I.O.L., Xu R. and Fan S.T., FTY720 induces apoptosis of human hepatoma cell lines through PI3-K-mediated Akt dephosphorylation, Carcinogenesis. 2004, 25(12): 2397-2405. |
| Lee K.W., Man K., Ho J.W.Y., Wang X., Poon R.T.P., Sun K.W., Ng T.P., Ng I.O.L., Xu R. and Fan S.T., Significance of the Rac signaling pathway in HCC cell motility: implications for a new therapeutic target, Carcinogenesis. 2005, 26(3): 681-687. |
| Li X.L., Man K., Ng T.P., Sun K.W., Lo C.M. and Fan S.T., The influence of phosphatidylinositol 3-kinase/Akt pathway on the ischemic injury during rat liver graft preservation, American Journal of Transplantation. 2005, 5(6): 1264-1275. |
| Man K., Ng T.P., Lee K.W., Lo C.M., Sun K.W., Li X., Zhao Y., Ho J.W.Y. and Fan S.T., FTY720 attenuates hepatic ischemia-reperfusion injury in normal and cirrhotic livers, American Journal of Transplantation. 2005, 5(1): 40-49. |
| Man K., Ng T.P., Lo C.M., Sun K.W., Zhao Y., Ho J.W.Y., Lee K.W. and Fan S.T., Hepatic I/R injury on small liver remnant promotes liver tumor growth and metastasis - activation of cell invasion and migration pathways (Abstract), The 20th International Congress of the Transplantation Society, Vienna, Austria, 5-10 September 2004. |
| Man K., Xu A., Xu A., Zhao Y., Lo C.M., Ng T.P., Sun K.W. and Fan S.T., Rescue of small-for-size fatty liver grafts injury by FTY720 and adiponectin combination therapy (Abstract), The 20th International Congress of the Transplantation Society, Vienna, Austria, 5-10 September 2004. |
| Zhao Y., Man K., Lo C.M., Ng T.P., Li X.L., Sun K.W., Lee K.W., Dai X.W. and Fan S.T., Attenuation of small-for-size liver graft injury by FTY720: significance of cell-survival Akt signaling pathway, American Journal of Transplantation. 2004, 4(9): 1399-1407. |
| Researcher : Tam PC |
| List of Research Outputs |
| Cheung M.C., Lee F.C.W., Chu S.S.M., Leung S.Y.L., Wong B.B.W., Ho K.L. and Tam P.C., Laparoscopic nephrectomy: an early experience at Queen Mary Hospital, Hong Kong Medical Journal. 2005, 11(1): 7-11. |
| Ho K.L., Wong B.B.W., Leung S.Y.L. and Tam P.C., Clinico-pathological correlations of incidental and symptomatic renal cell carcinoma (RCC), International Journal of Urology. 2004, 11(Suppl): A7. |
| Ho K.L., Tsu H.L., Wong B.B.W., Leung S.Y.L. and Tam P.C., Oncological outcomes of upper urinary tract transitional cell carcinoma (TCC), International Journal of Urology. 2004, 11(Suppl): A8. |
| Leung S.Y.L., Wong B.B.W., Cheung M.C., Lee F.C.W. and Tam P.C., A phase II trial of continuous, oral low-dose estramustine and etoposide chemotherapy in the treatment of symptomatic hormone-refractory prostate cancer (HRCP), International Journal of Urology. 2004, 11(Suppl): A16. |
| Leung S.Y.L., Wong B.B.W., Cheung M.C., Lee F.C.W. and Tam P.C., Day case transurethral resection - vaporization of the prostate (TURVP) for the treatment of benign prostatic hyperplasia - a prospective trial, International Journal of Urology. 2004, 11(Suppl): A13. |
| Leung S.Y.L., Chan A.C.Y., Wong B.B.W., Cheung M.C., Lee F.C.W. and Tam P.C., Management of febrile urinary tract infections (UTI) complicating transrectal ultrasound guided biopsy of the prostate (TRUSBx), International Journal of Urology. 2004, 11(Suppl): A19. |
| Leung S.Y.L., Wong B.B.W., Ho K.L., Cheung M.C., Lee F.C.W. and Tam P.C., Prospective double-blind randomized controlled trial on intrarectal administration of lidocaine gel vs. plain lubricant gel for pain control during transrectal ultrasound guided extensive 10-core prostate biopsy, International Journal of Urology. 2004, 11(Suppl): A9. |
| Leung S.Y.L., Cheung M.C., Wong B.B.W., Lee F.C.W. and Tam P.C., Transurethral ethanol ablation of the prostate (TEAP) for the management of acute retention of urine in patients with compromised medical risks, International Journal of Urology. 2004, 11(Suppl): A48-A49. |
| Luk J.M.C., Tong M.K., Mok B.B.W., Tam P.C., Yeung W.S.B. and Lee C.K.F., Sp 1 site is crucial for the mouse claudin-19 gene expression in the kidney cells, FEBS Letters . 2004, 578: 251-256. |
| Tam P.C., A large scale nocturia survey in Hong Kong (Invited), Asian Nocturia Forum, Cebu, Phillippines, 8 January 2005. |
| Tam P.C., Board Member (2002 - present), Asia Pacific Continence Advisory Panel. 2005. |
| Tam P.C., Chairman (2002 - present), Urology Board, The College of Surgeons of Hong Kong. 2005. |
| Tam P.C., Co-Director (1998 - present), Combined Renal Service, Queen Mary Hospital. 2005. |
| Tam P.C., Consultant & Chief (March 1997 - present), Department of Surgery, University of Hong Kong Medical Centre, Queen Mary Hospital. 2005. |
| Tam P.C., Corresponding Member (1996 - present), American Urological Association. 2005. |
| Tam P.C., Council Member (2004- present), Asia Pacific Society of Sexual Medicine. 2005. |
| Tam P.C., Council Member (2005 - present), The College of Surgeons of Hong Kong. 2005. |
| Tam P.C., Deputy Secretary General (1996 - present), Asian Surgical Association. 2005. |
| Tam P.C., Examiner in Conjoint Urology Fellowship Examination, College of Surgeons of Hong Kong & Royal College of Surgeons of Edinburgh. 2004. |
| Tam P.C., Honorary Consultant (1996 - present), Sexual Rehabilitation Service ReHabAid. 2005. |
| Tam P.C., Honorary Consultant (Urology) (1998 - present), Tung Wah Hospital. 2005. |
| Tam P.C. and Tam P.C., Male infertility: the role of urologist in the age of ICSI (Invited), 7th Asian Congress of Urology, Urological Association of Asia, Hong Kong, 4 November 2004. |
| Tam P.C., Management of erectile dysfunction: new trends and perspectives (Invited), The Federation's Annual Scientific Meeting 2004 - Men's Health, The Federation of Medical Societies of Hong Kong, Hong Kong, 18 December 2004. |
| Tam P.C., Management of male infertility: role of the urologist, Postgraduate Study Day, Department of Obstetrics & Gynaecology, Queen Mary Hospital, Hong Kong, 12 April 2005. |
| Tam P.C., Member (1990 - present), Central Renal Committee, Hospital Authority (Fomerly Hospital Service Department). 2005. |
| Tam P.C., Member (2000 - present), Working Group on Male Sexual and Reproductive Health, The Family Planning Association of Hong Kong. 2005. |
| Tam P.C., Member of Editorial Board (2005 - present), Hong Kong Medcial Journal. 2005. |
| Tam P.C., New advances in erectile dysfunction therapy (Invited), 9th Hong Kong Medical Forum, Hong Kong, 17 July 2004. |
| Tam P.C., Nocturia survey in Hong Kong, The Hong Kong Medical Diary. 2005, 10(7): 13. |
| Tam P.C., Optimizing the amangement of erectile dysfunction (Invited), 11th Annual Symposium on Male & Femal Dysfunction, Department of Obstetrics and Gynaecology, National University of Singapore & National University of Singapore, Singapore, 28 August 2004. |
| Tam P.C., Optimizing the management of erectile dysfunction (Invited), Advances in Therapeutics Course, organised by the British Medical Association, Hong Kong, 14 March 2005. 2005. |
| Tam P.C., Leung S.Y.L. and Wong B.B.W., Radical cystectomy; refining the techniques, BIU International. 2004, 94(Suppl2): 109-110. |
| Tam P.C., Transurethral resection of the prostate: reaffirming the gold standard, Hong Kong Medical Journal. 2005, 11(2): 76-78. |
| Tam P.C., Vice-Chairman (2003- present), Specialty Group in Urology Service, Hospital Authority. 2005. |
| Tam P.C., Visitiong Urologist (1992 - present), MacLehose Medical Rehabilitation Centre. 2005. |
| Tam P.C., 前列腺癌之成因及治療方法(Invited), Joint Prostate Cancer Seminar, organised by CK Cancer Institute and Plasmagene Limited, Hong Kong, 11 December 2004. |
| Tsu H.L., Cheung M.C., Chu S.S.M., Lee F.C.W. and Tam P.C., Laparoscopic live donor nephrectomy: is there any difference in outcome compared with its conventional open counterpart?, International Journal of Urology. 2004, 11(Suppl): A4. |
| Wong B.B.W., Cheung M.C., Leung S.Y.L., Lee F.C.W. and Tam P.C., A prospective, randomized study comparing transurethral resection of prostate (TURP) with transurethral resection - vaporization of prostate (TURVP) on treatment for acute urinary retention, International Journal of Urology. 2004, 11(Suppl): A11-A12. |
| Researcher : Tam PKH |
| Project Title: | Transgenesis animals as bioreactors: production of a new immunosuppressive protein CTLA4Ig by transgenesis |
| Investigator(s): | Tam PKH, Wong NS, Cheah KSE, Dallman M.J., Sun F.Z. |
| Department: | Surgery |
| Source(s) of Funding: | Vice-Chancellor's Office - General Award |
| Start Date: | 07/1997 |
| Abstract: |
| The use of transgenic farm animals as bioreactors is a potentially powerful and important new industry for the next century. This application of transgenic technology, in combination with the recent advance in ability to clone animals from adult cells, enhances the potential of transgenic animal bioreactors as major producers of therapeutic proteins. Therefore by initiating research in this area there are immediate and long-term benefits to Hong Kong and China. |
| Project Title: | Establishing a "train-the-trainers" programme for paediatric surgery in China |
| Investigator(s): | Tam PKH, Lin CL |
| Department: | Surgery |
| Source(s) of Funding: | S.K. Yee Medical Foundation - General Award |
| Start Date: | 10/1998 |
| Abstract: |
| To improve the standard of surgical care of children in China through the establishment of a scheme of "train-the-trainers"; to improve our understanding of special paediatric surgical issues relevant to the Chinese population (e.g. disease patterns, transferability of western "advances" to China etc.) through systematic exchanges with major centres in China and hence enhance our ability to deliver better surgical care to children in Hong Kong. |
| Project Title: | Expanding the "Train-the-Trainers" programme for paediatric surgery in China |
| Investigator(s): | Tam PKH, Lin CL, Zhang J.Z., Wang W.L., Shi C.R. |
| Department: | Surgery |
| Source(s) of Funding: | S.K. Yee Medical Foundation - General Award |
| Start Date: | 10/2000 |
| Abstract: |
| To improve the standard of surgical care of children in China through the consolidation and expansion of a scheme of "Train-the-Trainers"; to improve our understanding of special paediatric surgical issues relevant to the Chinese population (e.g. disease patterns, transferability of western "advances" to China etc) through systematic exchanges with major centres in China and hence enhance our ability to deliver better surgical care to children in Hong Kong; to promote modern concepts of medical education among leaders of the new generation of doctors through the introduction of structured training, problem-based learning, life-long learning, and the use of evidence-based medicine and information technology. |
| Project Title: | OX40/OX40L-costimulatory pathway in transplantation rejection and tolerance induction |
| Investigator(s): | Tam PKH, Tian L, Dallman M.J. |
| Department: | Surgery |
| Source(s) of Funding: | Competitive Earmarked Research Grants (CERG) |
| Start Date: | 09/2001 |
| Completion Date: | 08/2004 |
| Abstract: |
| To investigate the immunological role of OX40/OX40L in transplantation rejection in vitro, and in vivo using rat cardiac and intestinal allograft models; to explore the posibility of inducing donor specific tolerance by a combination approach of donor specific transfusion, OX40/OX40l pathway interruption and rapamycin administration; to compare the effects of OX40/OXL costimulatory blockade against CD28 costimulatory inhibition in transplanation models. |
| Project Title: | Sonic hedgehog signalling in chronic allograft rejection |
| Investigator(s): | Tam PKH, Tian L, Dallman M.J., Lamb J.R. |
| Department: | Surgery |
| Source(s) of Funding: | Competitive Earmarked Research Grants (CERG) |
| Start Date: | 09/2002 |
| Abstract: |
| To investigates the role of Notch, Sonic hedgehog (Shh) signalling in acute and chronic graft rejection in a rat model of small bowel transplantation; to study if the blockade of Shh signalling alone or in conjunction with the use of TFG-[beta] inhibitors can ameliorate chronic rejection. |
| Project Title: | The role of sonic hedgehog in immune system |
| Investigator(s): | Tam PKH, Tian L, Chan VSF, Lamb J.R. |
| Department: | Surgery |
| Source(s) of Funding: | Other Funding Scheme |
| Start Date: | 10/2002 |
| Abstract: |
| To elucidate the role of sonic hedgehog in CD4+ T cells activation and to identify its downstream targets suring T cell activation. |
| Project Title: | The role of T regulatory cell in the long-term survival of orthotopic small bowel allograft |
| Investigator(s): | Tam PKH, Tian L, Dallman M.J., Lamb J.R. |
| Department: | Surgery |
| Source(s) of Funding: | Incentive Award for RGC CERG Fundable But Not Funded Projects |
| Start Date: | 07/2003 |
| Abstract: |
| To determine the role of T reg cells in the long-term survival of small bowel allografts mediated by selected treatment with FK506. |
| Project Title: | Improving the survival and quality of life of children with cancers in China |
| Investigator(s): | Tam PKH, Wong IHN, Chan GCF, Ren Y, Lin CL, Li Z.Z., Zhang J.Z., Wang W.L., Shi C.R. |
| Department: | Surgery |
| Source(s) of Funding: | S.K. Yee Medical Foundation - General Award |
| Start Date: | 10/2003 |
| Abstract: |
| To improve the survival and quality of life of poor and sick children suffering from cancer through the establishment of a Chinese Children Cancer Consortium which will be responsible for the introduction and implementation of modern, comprehensive management protocols, and for training and educating health care workers around the country to adopt the new standard of cares for children with cancer. |
| Project Title: | The study of co-stimulatory function of sonic hedgehog in CD4+ lymphocytes |
| Investigator(s): | Tam PKH, Chan VSF, Lamb J.R. |
| Department: | Surgery |
| Source(s) of Funding: | Small Project Funding |
| Start Date: | 11/2003 |
| Abstract: |
| To study the distribution of Shh and its receptors on the surface of T cells during T cell activation; to study the effect of Shh on TH1 and TH2 cell differentiation; to identify the downstream targets of Shh signaling pathway in CD4+ T lymphocytes. |
| Project Title: | T cell memory and chronic rejection |
| Investigator(s): | Tam PKH |
| Department: | Surgery |
| Source(s) of Funding: | Incentive Award for RGC CERG Fundable But Not Funded Projects |
| Start Date: | 07/2004 |
| Abstract: |
| Refer to hard copy |
| Project Title: | Evaluation of HOXB5 as a new Hirschprung's disease susceptibility locus |
| Investigator(s): | Tam PKH, Lui VCH, Garcia-Barcelo MM |
| Department: | Surgery |
| Source(s) of Funding: | Small Project Funding |
| Start Date: | 11/2004 |
| Abstract: |
| To evaluate the human HOXB5 gene as a new Hirschsprung's disease susceptibility locus. |
| Project Title: | Further expansion of the "Train-the-Trainers" programme for paediatric surgery in China |
| Investigator(s): | Tam PKH, Wong KKY, Chan KL, Yip KF, Wang W.L., Shi C.R., Zhang J.Z., Zhan JH, Jin XQ |
| Department: | Surgery |
| Source(s) of Funding: | S.K. Yee Medical Foundation - General Award |
| Start Date: | 05/2005 |
| Abstract: |
| The project aims to improve the standard of surgical care of children in China; to improve understanding of special paediatric surgical issues relevant to the Chinese population; and to promote modern concepts of medical education among leaders of the new generation of doctors in China. |
| Project Title: | University strategic research theme: Genomics, Proteomics & Bioinformatics |
| Investigator(s): | Tam PKH, Leung FCC, Chen SF, Che CM, He Q, Ng KP |
| Department: | Surgery |
| Source(s) of Funding: | Seed Funding for Strategic Research Theme |
| Start Date: | 05/2005 |
| Abstract: |
| To facilitate multidisciplinary research in the areas of genomics, proteomics and bioinformatics. The three subthemes would be created, and an additional subtheme on thical, legal and social issues (ELSI) should be created. |
| List of Research Outputs |
| Bai Y.Z., Chan K.L. and Tam P.K.H., Early surgical intervention of prenatally diagnosed congenital cystic adenomatoid malformation, 38th Annual Meeting of the Pacific Association of Pediatric Surgery, Vancouver, Canada, 22-26 May 2005. |
| Chan K.K., Chen Y.S., Yau T.O., Fu M., Lui V.C.H., Tam P.K.H. and Sham M.H., Hoxb3 vagal neural crest-specific enhancer element for controlling enteric nervous system development, Developmental Dynamics. 2005, 233: 473-483. |
| Chan K.L., Tang M.H.Y. and Tam P.K.H., Non-cystic fibrosis meconium peritonitis: prenatal diagnosis, postnatal management and outcome, 38th Annual Meeting of the Pacific Association of Pediatric Surgery, Vancouver, Canada, 22-26 May 2005. |
| Chan V.S.F., Chau S.Y., Tian L., Kwong S.K.Y., Quackenbush J., Dallman M., Lamb J.R. and Tam P.K.H., Sonic hedgehog promotes CD4+ T lymphocyte proliferation by modulating a subset of CD28-targeted genes, 9th Basic Science Symposium of the Transplantation Society, LaBaule, France, 19-22 June 2005. |
| Chen Y., Lui V.C.H., Rooijen N.V. and Tam P.K.H., Depletion of intestinal resident macrophages prevents ischaemia reperfusion injury in gut, Gut. 2004, 53(12): 1772-1780. |
| Cheng W., Poon K.H., Lui V.C.H., Yong J.L., Law S.Y.K., So K.T., Tse K. and Tam P.K.H., Esophageal atresia and achalasia like esophageal dysmotility, Journal of Pediatric Surgery. 2004, 39(10): 1581-1583. |
| Fu M., Lui V.C.H., Sham M.H., Pachnis V. and Tam P.K.H., Sonic hedgehog regulates the proliferation, differentiation, and migration of enteric neural crest cells in gut., The Journal of Cell Biology. 2004, 166(5): 673-684. |
| Garcia-Barcelo M.M., Lui V.C.H., Fu M., Li L., Scherer S., Herbrick M.A., Van Heurn E. and Tam P.K.H., New HLBX9 mutations in Currarino patients, XXI Annual International Congress of the British Association of Paediatric Surgeons. Oxford, UK, July 27-30, 2004. |
| Garcia-Barcelo M.M., Ganster R.W., Lui V.C.H., Leon Y.Y., So M.T., Lau A.M.F., Fu M., Sham M.H., Knight J., Zannini M.S., Sham P.C. and Tam P.K.H., TTF-1 and RET promoter SNPs: regulation of RET transcription in Hirschsprung's disease, Human Molecular Genetics. 2005, 14(2): 191-204. |
| He Q., Zhu R., Ren Y., Tam P.K.H. and Chiu J., Serological protein profiling of neuroblastoma by proteinchip SELDI-TOF technology, Journal of Cellular Biochemistry. 2005, 95: 165-172. |
| Ho K.M.T., Li A.Z., Yiu M.K., Lee K.C., Lui V.C.H., Fung P.C.W., Yiu T.F. and Tam P.K.H., Altered expression of aquaporin-2 in human explants with chronic renal allograft dysfunction, BJU International. 2005, 95: 1104-1108. |
| Khoo U.S., Chan Y.K., Peiris J.S.M., Yip S.P., Liu W., Ngan H.Y.S., Tam P.K.H., Chan L.C. and Cheung A.N.Y., Association of ICAM3 genetic variant with Severe Acute Respiratory Syndrome (SARS)., HUGO's 10th Human Genome Meeting, 18-21 April 2005, Kyoto, Japan. 2005. |
| Lan L.C.L., Lin C.L. and Tam P.K.H., Central venous catheterization in children for parenteral nutrition delivery carry a higher risk for infection - experience in a tertiary referring hospital, 19th Congress of the Asian Association of Paediatric Surgeons, Hong Kong, 28 November - 1 December 2004. |
| Lan L.C.L., Lin C.L., Wong K.K.Y. and Tam P.K.H., Parenteral nutrition is a major risk factor for children undergoing central venous catheterization, 38th Annual Meeting of the Pacific Association of Pediatric Surgery, Vancouver, Canada, 22-26 May 2005. |
| Lan L.C.L., Lee K.K., Lin C.L., Wong K.K.Y. and Tam P.K.H., Placement of percutaneous endoscopic gastrostomy in children with ventriculoperitoneal shunt, 38th Annual Meeting of the Pacific Association of Pediatric Surgery, Vancouver, Canada, 22-26 May 2005. |
| Law M.L., Ngan E.S.W., Lui V.C.H., Tam P.K.H. and Sham M.H., The role of Sox 10 on survival and proliferation of enteric neural crest stem cells, 3rd Annual Meeting of International Society for Stem Cell Research.. 2005. |
| Li X., Tian L., Lamb J.R. and Tam P.K.H., Anti-TGF-beta prevents chronic rejection in a rat orthotopic small bowel transplantation model, IXth International Small Bowel Transplantation Symposium, Brussels, Belgium, 30 June - 2 July 2005. |
| Lui V.C.H., Fu M., Sham M.H. and Tam P.K.H., Sonic hedgehog (SHH) promotes proliferation and maintains multi-potency of enteric neural crest stem cells (NCSCs), 51st Annual International Congress of British Association of Paediatric Surgeons, Oxford, U.K. 27-30 July 2004. |
| Lui V.C.H., Fu M., Sham M.H. and Tam P.K.H., Sonic hedgehog (SHH) regulates the migration and differentiation of the enteric neural crest stem cells (NCSCs) in gastrointestinal tract, 51st Annual International Congress of British Association of Paediatric Surgeons, Oxford, U.K. 27-30 July 2004. |
| Ren Y., Chen Y., Li W., Jiang G., Liu Q., Chan H.M. and Tam P.K.H., Anti-sense gene therapy for human neuroblastoma by targeting disruption of macrophage migration inhibitory factor (MIF): in vitro and nude mice studies, 51st Annual International Congress of British Association of Paediatric Surgeons, Oxford, U.K. 27-30 July 2004. |
| Ren Y., Li W., Liu Q., Yu W.Y., Sun R.W.Y., Che C.M. and Tam P.K.H., Gold (III) porphyrines: a novel chemotherapeutic agent for human neuroblastoma, 51st Annual International Congress of British Association of Paediatric Surgeons, Oxford, U.K. 27-30 July. 2004. |
| Ren Y., He Q., Fan J.Q., Jones B., Zhou Y., Xie Y., Cheung C.Y., Wu A.Y.Y., Chiu J., Peiris J.S.M. and Tam P.K.H., The use of proteomics in the discovery of serum biomarkers from patients with severe acute respiratory syndrome, Proteomics. 2004, 4: 3477-3484. |
| Ren Y., Lin C.L., Li Z., Chen X.Y., Huang X., Lui V.C.H., Nicholls J.M., Lan H.Y. and Tam P.K.H., Up-regulation of macrophage migration inhibitory factor in infants with acute neonatal necrotizing enterocolitis, Histopathology. 2005, 46(6): 659-667. |
| Shi J., Zheng D., Liu Y., Sham M.H., Tam P.K.H., Farzaneh F. and Xu R., Overexpression of soluble TRAIL induces apoptosis in human lung adenocarcinoma and inhibits growth of tumor xenografts in nude mice., Cancer Research. 2005, 65(5): 1687-1692. |
| Tam P.K.H., A surgeon-scientist's odyssey: from the histology of Hirschsprung's disease to genomics of the International HapMap project [Invited Lecture], Grand Rounds of Department of Surgery, The University of British Columbia, 25 May 2005. 2005. |
| Tam P.K.H., Genomic and stem cell technologies for surgical applications [Invited Lecture], 19th Congress of the Asian Association of Paediatric Surgeons, Hong Kong, 28 November - 1 December 2004. 2004. |
| Tam P.K.H., Hirschsprung's disease and allied conditions, Seminars in Pediatric Surgery. 2004, 13(4). |
| Tam P.K.H., Tian L., Li X. and Lamb J.R., Inhibition of sonic hedgehog signaling reduces chronic allograft rejection in rat small bowel transplantation, IXth International Small Bowel Transplantation Symposium, Brussels, Belgium, 30 June - 2 July 2005. |
| Tam P.K.H., Tian L., Li X., Dallman M. and Lamb J.R., Inhibition of sonic hedgehog singaling reduces chronic allograft rejection in rat small bowel transplantation, 9th Basic Science Symposium of the Transplantation Society, LaBaule, France, 19-22 June 2005. |
| Tam P.K.H. and Garcia-Barcelo M.M., Molecular genetics of Hirschsprung's disease, Seminars in Pediatric Surgery. 2004, 13(4): 236-248. |
| Tam P.K.H., Preface, Seminars in Pediatric Surgery. 2004, 13(4): 223. |
| Tam P.K.H., Presentation on latest development on research in the University of Hong Kong [Invited Lecture - PVC], U21 Vice-Presidents (VP)/Deputy Vice-Chancellors (Research) (DVC[R]) International Research Collaboration Initiative Meeting 2005, Sydney, Australia, 20-22 April 2005. 2005. |
| Tam P.K.H., Regional efforts in promoting Chinese medicine in Hong Kong [Invited Lecture - PVC], Medicine in the 21st Century, Tri-Conference & Bio-Forum 2004, Shanghai, China, 24-27 July 2004. 2004. |
| Tam P.K.H., The University of Hong Kong's strategy on stem cell research [Invited Lecture], Joint Seminar of Centre of Developmental Biology (CBD) & the University of Hong Kong, Kobe, Japan, 15 April 2005. 2005. |
| Tam P.K.H., Train-the-Trainer program: Hong Kong perspective [Invited Lecture], 19th Congress of the Asian Association of Paediatric Surgeons, Hong Kong, 28 November - 1 December 2004. 2004. |
| Tian L., Yuan Z., Cai Q., Lui Y., Thompson P., Tam P.K.H. and Lamb J.R., Combined treatment with cyclosporin A and rosiglitazone prevents chronic allograft rejection, 9th Basic Science Symposium of the Transplantation Society, LaBaule, France, 19-22 June 2005. |
| Tian L., Lui Y., Lamb J.R. and Tam P.K.H., The effect of blocking CD28 and CD134 co-stimulatory pathways in rat cardiac transplant, 9th Basic Science Symposium of the Transplantation Society, LaBaule, France, 19-22 June 2005. |
| Wang Q., Tam P.K.H. and Chan K.L., Congenital cystic adenomatoid malformation in children: 21 cases about studies and review of the literature, 19th Congress of the Asian Association of Paediatric Surgeons, Hong Kong, 28 November - 1 December 2004. |
| Wong I.H.N., Chan J.K.Y. and Tam P.K.H., Epigenetic deregulation of cell cycle progression: a novel therapeutic strategy for pediatric cancer, 38th Annual Meeting of the Pacific Association of Pediatric Surgery, Vancouver, Canada, 22-26 May 2005. |
| Wong K.K.Y., Fan A.H., Lan L.C.L., Lin C.L. and Tam P.K.H., Effective antibiotic regime for postoperative acute cholangitis in biliary atresia - an evolving scene, Journal of Pediatric Surgery. 2004, 39(12): 1800-1802. |
| Wong K.K.Y., Lan L.C.L., Yip P.K.F. and Tam P.K.H., Laparoscopic resection of tracheobronchial remnants causing congenital esophageal stenosis, 38th Annual Meeting of the Pacific Association of Pediatric Surgery, Vancouver, Canada, 22-26 May 2005. |
| Wong K.K.Y., Lan L.C.L., Lin C.L., Chan A.W.S. and Tam P.K.H., Mucous fistula refeeding in premature neonates with enterostomies, Journal of Pediatric Gastroenterology and Nutrition. 2004, 39: 43-45. |
| Wong K.K.Y., Khong P.L., Lin C.L., Lam W.W.M., Lan L.C.L. and Tam P.K.H., Post-operative magnetic resonance evaluation of children after laparoscopic anorectoplasty for imperforate anus, International Journal of Colorectal Disease. 2005, 20(1): 33-37. |
| Wong K.K.Y. and Tam P.K.H., Press release - Laparoscopic-assisted Rectoanoplasty for Imperforate Anus, 2004. |
| Wong K.K.Y., Wong J.S.W., Lan L.C.L. and Tam P.K.H., Setting up a laparoscopic surgical service: experience in an Asian paediatric surgical unit, 19th Congress of the Asian Association of Paediatric Surgeons, Hong Kong, 28 November - 1 December 2004. |
| Wong K.K.Y., Lan L.C.L., Lin C.L. and Tam P.K.H., Superior mesenteric artery syndrome: are we over-diagnosing in children?, 19th Congress of the Asian Association of Paediatric Surgeons, Hong Kong, 28 November - 1 December 2004. |
| Wong K.K.Y., Lan L.C.L., Lin C.L. and Tam P.K.H., The electronic surgical unit: a stride into the 21st century, 19th Congress of the Asian Association of Paediatric Surgeons, Hong Kong, 28 November - 1 December 2004. |
| Wong K.K.Y., Lan L.C.L., Lin C.L. and Tam P.K.H., The use of positron emission tomography in detecting hepatoblastoma recurrence - a cautionary tale, Journal of Pediatric Surgery. 2004, 39(12): 1779-1781. |
| Wong K.K.Y., Chung P.H.Y., Lan L.C.L., Lin C.L. and Tam P.K.H., Trends in the prevalence of H. pylori in symptomatic children in the era of eradication, 38th Annual Meeting of the Pacific Association of Pediatric Surgery, Vancouver, Canada, 22-26 May 2005. |
| Xu R., Li H., Cai K., Sham M.H., Tam P.K.H. and Lam K.S.L., Distribution, pathway and dynamics intake of recombinant adeno-associated virus and gene expression in the gut after oral administration, 10th SCBA International Symposium, Beijing, China, 18-23 July 2004. P2-13-17. |
| Yip K.F., Tam P.K.H. and Li M.K.W., Laparoscopic flip-flap hernioplasty: an innovative technique for pediatric hernia surgery, Surgical Endoscopy. 2004, 18: 1126-1129. |
| Yip P.K.F., Tam P.K.H. and Li M.K.W., A simple and secure method to fix laparoscopic trochars in children, IPEG's 14th Annual Congress for Endosurgery in Children, Venice Lido, Italy, 1-4 June 2005. |
| Yip P.K.F., Tam P.K.H. and Li M.K.W., Intracorporeal tautline knot: a fast method to secure a laparoscopic continuous suturing, IPEG's 14th Annual Congress for Endosurgery in Children, Venice Lido, Italy, 1-4 June 2005. |
| Researcher : Tang TCM |
| List of Research Outputs |
| Ng K.K.C., Lam C.M., Poon R.T.P., Shek T.W.H., Yu W.C., To J.Y.T., Wo Y.H., Lau C.P.Y., Tang T.C.M., Ho D.W.Y. and Fan S.T., Porcine liver: morphological characteristics and cell viability at experimental radiofrequency ablation with internally cooled electrodes, Radiology. 2005, 235(2): 478-486. |
| Tang T.C.M., Poon R.T.P., Guan X.Y. and Fan S.T., Celecoxib suppresses HCC development via the cell cycle arrest pathway (Poster Presentation), The 96th Annual Meeting of the American Association for Cancer Research, Anaheim, California, U.S.A., 16-20 April 2005. |
| Tang T.C.M., Poon R.T.P., Lau C.P.Y., Xie D. and Fan S.T., Cytosolic cyclooxygenase-2 levels correlate with cytosolic vascular endothelial growth factor levels and tumor invasiveness in human hepatocellular carcinoma (Abstract), The 1st Annual Conference for the Organisation for Oncology and Translational Research, Hong Kong, 15-16 October 2004. |
| Tang T.C.M., Poon R.T.P., Guan X.Y. and Fan S.T., The significance of cyclooxygenase-2 in hepatocellular carcinoma (Abstract), The 6th Annual Scientific Meeting, Centre for the Study of Liver Disease, The University of Hong Kong, Hong Kong, 8 January 2005. |
| Tang T.C.M., Poon R.T.P., Lau C.P.Y., Xie D. and Fan S.T., Tumor cyclooxygenase-2 levels correlate with tumor invasiveness in human hepatocellular carcinoma, World Journal of Gastroenterology. 2005, 11(13): 1896-1902. |
| Researcher : Tian J |
| List of Research Outputs |
| Tian J., The effect of nano silver particles on cytokine expression and wound healing in an animal thermal injury model, Thesis, Master of Philosophy, The University of Hong Kong. 2004. |
| Researcher : Tian L |
| Project Title: | The study of gene expression pattern in chronic rejection and the mechanism of drug action in the sequential treatment regimen resulting in long-term allograft survival in small bowel transplantation in rat |
| Investigator(s): | Tian L, Tam PKH, Lamb J.R. |
| Department: | Surgery |
| Source(s) of Funding: | Seed Funding Programme for Basic Research |
| Start Date: | 02/2004 |
| Completion Date: | 01/2005 |
| Abstract: |
| To explore the global gene expression patterns of the intra-graft and CD4+ cells in the animals treated with FK506 alone or in combination with Rapa; to identify the novel genes that highly regulated by this treatment. |
| List of Research Outputs |
| Chan V.S.F., Chau S.Y., Tian L., Kwong S.K.Y., Quackenbush J., Dallman M., Lamb J.R. and Tam P.K.H., Sonic hedgehog promotes CD4+ T lymphocyte proliferation by modulating a subset of CD28-targeted genes, 9th Basic Science Symposium of the Transplantation Society, LaBaule, France, 19-22 June 2005. |
| Huang F., Ma L., Wu A.Y.Y., Tian L., Chan K.W., Trendell-Smith N.J., Lam A.C., Chan A.K.L., Lo C.K., Chik S.C.C., Ko K.H., To K.W., Kam S.K., Fong L.P., Li X.S., Leung S.Y., Ng M.H., Stott D.I., Liew F.Y. and MacPherson G.G., Systemic autoimmune disease induced by dendritic cells that have captured necrotic but not apoptotic dying cells, Proceedings of the 12th International Congress of Immunology and the 4th Annual Conference of FOCIS, Montreal, Canada, July 18-23, 2004. 2004. |
| Li X., Tian L., Lamb J.R. and Tam P.K.H., Anti-TGF-beta prevents chronic rejection in a rat orthotopic small bowel transplantation model, IXth International Small Bowel Transplantation Symposium, Brussels, Belgium, 30 June - 2 July 2005. |
| Tam P.K.H., Tian L., Li X. and Lamb J.R., Inhibition of sonic hedgehog signaling reduces chronic allograft rejection in rat small bowel transplantation, IXth International Small Bowel Transplantation Symposium, Brussels, Belgium, 30 June - 2 July 2005. |
| Tam P.K.H., Tian L., Li X., Dallman M. and Lamb J.R., Inhibition of sonic hedgehog singaling reduces chronic allograft rejection in rat small bowel transplantation, 9th Basic Science Symposium of the Transplantation Society, LaBaule, France, 19-22 June 2005. |
| Tian L., Yuan Z., Cai Q., Lui Y., Thompson P., Tam P.K.H. and Lamb J.R., Combined treatment with cyclosporin A and rosiglitazone prevents chronic allograft rejection, 9th Basic Science Symposium of the Transplantation Society, LaBaule, France, 19-22 June 2005. |
| Tian L., Lui Y., Lamb J.R. and Tam P.K.H., The effect of blocking CD28 and CD134 co-stimulatory pathways in rat cardiac transplant, 9th Basic Science Symposium of the Transplantation Society, LaBaule, France, 19-22 June 2005. |
| Researcher : Ting ACW |
| List of Research Outputs |
| Cheng S.W.K., Ting A.C.W., Ho P. and Poon J.T.C., Aortic aneurysm morphology in Asians: features affecting endovascular stent graft application and design, Journal of Endovascular Therapy. 2004, 11: 605-612. |
| Cheng S.W.K., Ting A.C.W., Ho P. and Poon J.T.C., Aortic aneurysm morphology in Asians: features affecting endovascular stent graft application and design, The Nineteenth Annual Meeting of the Western Vascular Society, Victoria, Canada, 11-14 September 2004. |
| Cheuk L.Y., Ting A.C.W. and Cheng S.W.K., Detection of C. pneumoniae by polymerase chain reaction-enzyme immunoassay in abdominal aortic aneurysm walls and its association with rupture, European Journal of Vascular and Endovascular Surgery. 2005, 29(2): 150-155. |
| Ho P., Ting A.C.W. and Cheng S.W.K., Blood loss transfusion in elective abdominal aortic aneurysm surgery, Australian and New Zealand Journal of Surgery. 2004, 74(8): 631-634. |
| Ho P., Poon J.T.C., Ting A.C.W. and Cheng S.W.K., Routine immediate tracheostomy after ruptured abdominal aortic aneurysm repair improves hospital mortality, The 6th International Congress of Asian Vascular Society & 11th Conference of Vascular Society of India, Bangalore, India, 3-6 November 2004. |
| Mok V.W.K., Ting A.C.W., Law S.Y.K., Wong K.H., Cheng S.W.K. and Wong J., Combined endovascular stent grafting and endoscopic injection of fibrin sealant for aortoenteric fistula complicating esophagectomy, Journal of Vascular Surgery. 2004, 40(6): 1234-1237. |
| Ting A.C.W., Cheng S.W.K., Ho P. and Poon J.T.C., Endovascular repair for multiple Salmonella mycotic aneurysms of the thoracic aorta presenting with Cardiovocal syndrome, European Journal of Cardiothoracic Surgery. 2005, 26(1): 221-224. |
| Ting A.C.W., Surgical treatment for advanced chronic venous insufficiency in Hong Kong, Thesis, Master of Surgery, The University of Hong Kong. 2004. |
| Ting A.C.W., Cheng S.W.K., Ho P., Poon J.T.C., Wong Wu L.H. and Cheung G.C.Y., Surgical treatment for advanced chronic venous insufficiency in Hong Kong, Annals of the College of Surgeons of Hong Kong. 2004, 8(4): 135-140. |
| Ting A.C.W., Cheng S.W.K., Ho P., Poon J.T.C., Wong Wu L.H. and Cheung G.C.Y., Surgical treatment of advanced chronic venous insufficiency in Hong Kong, Second Chinese Venous Forum, Shanghai, China, 4-5 June 2005. 2005. |
| Ting A.C.W., Cheng S.W.K., Ho P., Poon J.T.C. and Tsu J.H.L., Surgical treatment of infected aneurysms and pseudoaneurysms of the thoacic and abdominal aorta, American Journal of Surgery. 2005, 189(2): 150-154. |
| Yiu W.K., Ting A.C.W. and Cheng S.W.K., Does endovascular repair of infrarenal AAA effect renal function?, The 6th International Congress of Asian Vascular Society & 11th Conference of Vascular Society of India, Bangalore, India, 3-6 November 2004. |
| Researcher : To JYT |
| List of Research Outputs |
| Ho D.W.Y., Yang Z., Lau C.K., To J.Y.T., Luk J.M.C. and Fan S.T., The therapeutic role of cardiotrophin-1 in a rat model with fulminant hepatic failure (Abstract), The 6th Annual Scientific Meeting, Centre for the Study of Liver Disease, The University of Hong Kong, Hong Kong, 8 January 2005. |
| Ng K.K.C., Lam C.M., Poon R.T.P., Shek T.W.H., To J.Y.T., Wo Y.H., Ho D.W.Y. and Fan S.T., Comparison of systemic responses of radiofrequency ablation, cryotherapy, and surgical resection in a porcine liver model, Annals of Surgical Oncology. 2004, 11(7): 650-657. |
| Ng K.K.C., Lam C.M., Poon R.T.P., Shek T.W.H., Yu W.C., To J.Y.T., Wo Y.H., Lau C.P.Y., Tang T.C.M., Ho D.W.Y. and Fan S.T., Porcine liver: morphological characteristics and cell viability at experimental radiofrequency ablation with internally cooled electrodes, Radiology. 2005, 235(2): 478-486. |
| Yang Z., Poon R.T.P., To J.Y.T., Ho D.W.Y. and Fan S.T., The potential role of hypoxia inducible factor 1a in tumor progression after hypoxia and chemotherapy in hepatocellular carcinoma, Cancer Research. 2004, 64(15): 5496-5503. |
| Researcher : Toi M |
| List of Research Outputs |
| Zhu L., Chow L.W.C., Loo T.Y., Guan X.Y. and Toi M., Her2/neu expression predicts the response to antiaromatase neoadjuvant therapy in primary breast cancer: subgroup analysis from celecoxib antiaromatase neoadjuvant trial, Clinic Cancer Research. 2004, 10(14): 4639-4644. |
| Researcher : Tong CSW |
| List of Research Outputs |
| Ho J.W.Y., Poon R.T.P., Tong C.S.W. and Fan S.T., Clinical significance of serum vascular cell adhesion molecule-1 levels in patients with hepatocellular carcinoma, World Journal of Gastroenterology. 2004, 10(14): 2014-2018. |
| Poon R.T.P., Ho J.W.Y., Tong C.S.W., Lau C.P.Y., Ng I.O.L. and Fan S.T., Prognostic significance of serum vascular endothelial growth factor and endostatin in patients with hepatocellular carcinoma, British Journal of Surgery. 2004, 91(10): 1354-1360. |
| Researcher : Tong MK |
| List of Research Outputs |
| Luk J.M.C., Tong M.K., Mok B.B.W., Tam P.C., Yeung W.S.B. and Lee C.K.F., Sp 1 site is crucial for the mouse claudin-19 gene expression in the kidney cells, FEBS Letters . 2004, 578: 251-256. |
| Researcher : Tsui HT |
| List of Research Outputs |
| Man K., Lee K.W., Liang T.B., Lo C.M., Fung P.C.W., Tsui H.T., Li X.L., Ng T.P. and Fan S.T., FK409 ameliorates small-for-size liver graft injury by attenuation of portal hypertension and down-regulation of Egr-1 pathway, Annals of Surgery. 2004, 240(1): 159-168. |
| Researcher : Tsui TY |
| Project Title: | Identification possible role of heme oxygenase-1 on the regulation of T cell activation |
| Investigator(s): | Tsui TY, Bach F.H. |
| Department: | Surgery |
| Source(s) of Funding: | Seed Funding Programme for Basic Research |
| Start Date: | 02/2004 |
| Abstract: |
| To identify the possible role of HO-1 in the process of T cell activation. The findings obtained from this study might be essential in the establishment of the link between cellular defense system and the T cell immunity. HO-1 and its products could be used as novel therapeutic agents to control the disorders of T cell immunity in the future. |
| List of Research Outputs |
| Researcher : Wang J |
| List of Research Outputs |
| Luk J.M.C., Wang P., Wang J. and Fan S.T., Hepatic potential of bone marrow stromal cells after co-culture with damaged liver tissues and intraportal transplantation in cirrhotic liver, The 34th Annual Scientific Meeting of the Australasian Society for Immunology and 8th International Conference on Human Leucocyte Differentiation Antigens (HLDA8), Adelaide, Australia, 12-16 December 2004. |
| Luk J.M.C., Wang P.P., Wang J., Lau G.K. and Fan S.T., Hepatocyte-like phenotypes of bone marrow stromal cells after co-culture with damaged liver tissues and intraportal transplantation in cirrhotic liver, Hepatology. 2004, 40 (Supplement 1): LB-16, 733A. |
| Researcher : Wang P |
| List of Research Outputs |
| Luk J.M.C., Wang P., Wang J., Lau G. and Fan S.T., Hepatocyte-like phenotypes of bone marrow stromal cells after co-culture with damaged liver tissues and intraportal transplantation in cirrhotic liver (Abstract), The 55th Annual Meeting of the American Association for the Study of Liver Diseases, Boston, USA, 29 October – 2 November 2004. |
| Researcher : Wang Q |
| List of Research Outputs |
| Wang Q., Tam P.K.H. and Chan K.L., Congenital cystic adenomatoid malformation in children: 21 cases about studies and review of the literature, 19th Congress of the Asian Association of Paediatric Surgeons, Hong Kong, 28 November - 1 December 2004. |
| Researcher : Wang W |
| List of Research Outputs |
| Yi C., Li Z., Yuan K., Qu X., Chen J., Wang G., Zhang H., Luo H., Zhu L., Jiang P., Chen L., Shen Y., Luo M., Zuo G., Hu J., Duan D., Nie Y., Shi X., Wang W., Han Y., Li T., Liu Y., Ding M., Deng H. and Xu X., Small molecules blocking the entry of SARS-Co V into host, Journal of Virology. 2004, 78(2)): 11334-11339. |
| Researcher : Wang X |
| List of Research Outputs |
| Chua C.W., Lee T.W., Ling M.T., Man K., Ho J.W.Y., Ho J.W.Y., Ho J.W.Y., Ho J.W.Y., Ho J.W.Y., Wang X. and Wong Y.C., FTY720, a fungus metabolite, inhibits in vivo growth of androgen-independent prostate cancer, International Journal of Cancer. 2005, Equib ahead of print. |
| Luk J.M.C., Lee C.K.F., Wang X. and Fan S.T., Recognition of monoclonal antibodies against alternative splicing of liver intestine cadherin (Cdh17) in hepatocellular carcinoma , The 34th Annual Scientific Meeting of the Australasian Society for Immunology and 8th International Conference on Human Leucocyte Differentiation Antigens (HLDA8), Adelaide, Australia, 12-16 December 2004. |
| Wang X., Luk J.M.C., Leung P.L., Wong W.Y., Stanbridge E.J. and Fan S.T., Alternative mRNA splicing of liver intestine-cadherin in hepatocellular carcinoma, Clinical Cancer Research. 2005, 11(2 Pt 1): 483-489. |
| Wang X., Luk J.M.C., Leung P.L., Ho D.W.Y. and Fan S.T., Overexpressing LI-cadherin genetic polymorphisms (651C/T, IVS6+35A/G) is associated with susceptibility to HCC (Abstract), The 4th International Meeting on Hepatocellular Carcinoma: Eastern and Western Experiences, Hong Kong, 14-16 December 2004. |
| Wang X., Luk J.M.C., Leung P.L., Ho D.W.Y. and Fan S.T., Overexpression LI-cadherin genetic polymorphisms (651C/T, IVS6+35A/G) is associated with susceptibility to HCC (Abstract), Asian Journal of Surgery. 2005, 28(Suppl 2): S107. |
| Wang X., Luk J.M.C., Leung P.L. and Fan S.T., Overexpression of LI-cadherin genetic polymorphisms (651C/T, IVS6+35A/G) is associated with susceptibility to hepatocellular carcinoma (Abstract), The 6th Annual Scientific Meeting, Centre for the Study of Liver Disease, The University of Hong Kong, Hong Kong, 8 January 2005. |
| Researcher : Wei WI |
| Project Title: | Intra-arterial chemoradiation for advanced head and neck cancer |
| Investigator(s): | Wei WI, Sham JST |
| Department: | Surgery |
| Source(s) of Funding: | Other Funding Scheme |
| Start Date: | 07/2002 |
| Abstract: |
| To see if chemotherapy and radiotherapy given can help patients with advanced head and neck cancer. |
| Project Title: | Management of snoring and OSA |
| Investigator(s): | Wei WI, Ho WK |
| Department: | Surgery |
| Source(s) of Funding: | Other Funding Scheme |
| Start Date: | 09/2002 |
| Abstract: |
| To find the incidence of snoring and OSA and advance their treatments. |
| Project Title: | Quantitative analysis of plasma Epstein-Barr-Virus DNA in nasopharyngeal carcinoma after salvage nasopharyngectomy |
| Investigator(s): | Wei WI |
| Department: | Surgery |
| Source(s) of Funding: | Other Funding Scheme |
| Start Date: | 09/2002 |
| Abstract: |
| To study early detection of recurrence after radiotherapy for nasopharyngeal cancer. |
| Project Title: | Modifications of techniques of cochlear implantation |
| Investigator(s): | Wei WI, Au DKK, Ho WK |
| Department: | Surgery |
| Source(s) of Funding: | Other Funding Scheme |
| Start Date: | 09/2002 |
| Abstract: |
| To study the technique and mode of insertion of cochlear implant aiming to improve the efficacy of the implant. |
| Project Title: | Efficacy of anti-snoring therapy in different ethnic group |
| Investigator(s): | Wei WI, Hormann K. |
| Department: | Surgery |
| Source(s) of Funding: | Germany/Hong Kong Joint Research Scheme |
| Start Date: | 01/2003 |
| Completion Date: | 12/2004 |
| Abstract: |
| To identify the differences in the perception of snoring between caucasians and orientals; to identify the variations in anatomical structures leading to snoring and the social effects of snoring between 2 races; to evaluate the efficacy of anti-snoring therapy in the 2 races. |
| Project Title: | VEGF in nasopharyngeal cancer |
| Investigator(s): | Wei WI, Kwong DLW, Poon RTP |
| Department: | Surgery |
| Source(s) of Funding: | Other Funding Scheme |
| Start Date: | 03/2003 |
| Abstract: |
| To carry out early detection of nasopharyngeal cancer before radiotherapy and after treatment. |
| Project Title: | Study the spread of aerosol during tracheostomy or intubation |
| Investigator(s): | Wei WI, Sham JST, Irwin MG |
| Department: | Surgery |
| Source(s) of Funding: | Other Funding Scheme |
| Start Date: | 04/2003 |
| Abstract: |
| To investigate the distance and pattern of aerosol spread during surgical procedures in application to SARS. |
| Project Title: | Cochlear implant for 14 profoundly deaf children in China |
| Investigator(s): | Wei WI, Au DKK, Hui Y |
| Department: | Surgery |
| Source(s) of Funding: | S.K. Yee Medical Foundation - General Award |
| Start Date: | 10/2003 |
| Abstract: |
| To help Chinese children who are profoundly deaf in China to receive the cochlear implant, so that they will be able to hear, speak and to receive education effectively. |
| Project Title: | Speech rehabilitation after total laryngectomy - self help and mutual help |
| Investigator(s): | Wei WI, Ho WK, Ng HS, Ho M.L., Kwok I.C.L. |
| Department: | Surgery |
| Source(s) of Funding: | S.K. Yee Medical Foundation - General Award |
| Start Date: | 10/2003 |
| Abstract: |
| To visit the hospitals and centres in China where total laryngectomy is performed for patients suffering from cancer of the larynx. |
| Project Title: | Head and neck course in China - to teach techniques of contemporary operations and patient care for doctors and nurses working in underdeveloped areas in China. This will benefit those poor patients suffereing from head and neck cancer in China |
| Investigator(s): | Wei WI, Lam LK, Hui Y, Ng WM, Lo E.L.C., Fong W.W.Y., Yue S.W. |
| Department: | Surgery |
| Source(s) of Funding: | S.K. Yee Medical Foundation - General Award |
| Start Date: | 10/2003 |
| Abstract: |
| To teach head and neck surgeons in China the contemporary methods of managing patients suffering from head and neck cancer and also to introduce the concept of optimal nursing care for these patients. |
| List of Research Outputs |
| Au D.K.K., Hui Y., Chow C.K. and Wei W.I., 香港失聰幼兒早期人工耳蝸植入後的聽力和言語康復, Chinese Scientific Journal of Hearing and Speech Rehabilitation. 2004, 6: 14-16. |
| Au D.K.K., Chu K.M.Y., Chow C.K., Hui Y. and Wei W.I., Cognitive abilities of patients with cochlear implant in the discrimination of tone stimuli with minimal contrast, Cochlear Implant International, The Proceedings of the Fourth Asian-Pacific Symposium on Cochlear Implant and Related Sciences, Taipei, Taiwan, 2003. 2004, 5 (Suppl. 1): 179-181. |
| Chan H.H.L., Wong S.Y., Ho W.S., Lam L.K. and Wei W.I., The use of pulsed dye laser for the prevention and treatment of hypertrophic scars in Chinese persons, Dermatologic Surgery. 2004, 30: 987-994. |
| Chu K.M.Y., Au D.K.K., Hui Y., Chow C.K. and Wei W.I., Short electrode insertion in cochlear implantation: Speech perception performance of Cantonese-speaking subjects, Acta Oto-Laryngologica. 2005, 125: 718-724. |
| Chu K.M.Y., Au D.K.K., Hui Y., Chow C.K., Wong R.K. and Wei W.I., Short electrode insertion on cochlear implants: performance on speech perception, Cochlear Implant International, The Proceedings of the Fourth Asian-Pacific Symposium on Cochlear Implant and Related Sciences, Taipei, Taiwan, 2003. 2004, 5 (Suppl 1): 126-128. |
| Ganly I., Patel S.G., Singh B., Kraus D.H., Bridger P.G., Cantu G., Cheesman A., De Sa G., Donald P., Fliss D., Gullane P., Janecka I., Kamata S.E., Kowalski L.P., Levine P., Medina L.P., Pradhan S., Schramm V., Snyderman C., Wei W.I. and Shah J.P., Complications of craniofacial resection for malignant tumors of the skull base: report of an International Collaborative Study, Head Neck. 2005, 27: 445-451. |
| Genden E.M., Rinaldo A., Suarez C., Wei W.I., Bradley P.J. and Ferlito A., Complications of free flap transfers for head and neck reconstruction following cancer resection, Oral Oncology. 2004, 40: 979-984. |
| Ho W.K., Ng W.M. and Wei W.I., Laryngectomy for thyroid cancer involving the upper aerodigestive tract. , 6th International Conference on Head and Neck Cancer. . Washington, USA, 2004. |
| Ho W.K., Ng W.M., Wei W.I. and Yuen P.W., Ortner’s Syndrome: A radiological diagnosis. Poster presentation, 12th Annual Scientific Meeting, Hong Kong College of Radiologists. . Hong Kong, 2004. |
| Hui Y., Wong S.Y., Ho W.K. and Wei W.I., (2) OT 43 A prospective controlled double-blind trial of great auricular nerve preservation at parotidectomy. Am J Surg. 2003 Jun;185(6):574-9, In: Paparella MM, Otto RA, Keefe MA, Year Book of Otolaryngology-Head and Neck Surgery 2004. Mosby, 2004, (2) OT 43. |
| Lam K.Y., Lo C.Y. and Wei W.I., Warthin-like tumor variant of the papillary thyroid carcinoma: a case with dedifferentiation (anaplastic changes) and aggressive biological behavior, Endocrine Pathology. 2005, 16: 83-89. |
| Lau S.K.P., Woo P.C.Y., Wong B.H.L., Tsoi H.W., Woo G.K.S., Poon R.W.S., Chan K.H., Wei W.I., Peiris J.S.M. and Yuen K.Y., Detection of severe acute respiratory syndrome (SARS) coronavirus nucleocapsid protein in sars patients by enzyme-linked immunosorbent assay., Journal of clinical microbiology. 2004, 42(7): 2884-9. |
| Liu C.L., Fan S.T., Lo C.M., Wei W.I., Chan S.C., Yong B.H., Lai C.L. and Wong J., Operative outcomes of adult-to-adult right lobe live donor liver transplantation: a comparative study with cadaveric whole-graft liver transplantation in a single center (Abstract), The 20th International Congress of the Transplantation Society, Vienna, Austria, 5-10 September 2004. |
| Ng W.M. and Wei W.I., Elimination of palatal fistula after the mazillary swing procedure, Head & Neck. 2005, 27: 608-612. |
| Wei W.I., Advances in surgical management of oral cancer, 20th Anniversary of the Korean Society of Head & Neck Oncology, Seoul, Korea, 19-20 November. 2004. |
| Wei W.I., Affilated Hospital of Guiyang Medical college, Guiyang, Guizhou, China, 27-28 November 2004. 2004. |
| Wei W.I., Associate Editor (January 1985 - present), Asian Journal of Surgery. 2005. |
| Wei W.I., Auris Nasus Larynx, Editorial Board Member January 2005-December 2009. 2005. |
| Wei W.I., Chairman and Panel Member, "Nasopharynx infratemporal fossa and cranial cavity", 4th International Skull Base Congress, Sydney, Australia, 31 October - 4 November. 2004. |
| Wei W.I., Combined therapy for Unresectable and Nasopharyngeal Cancer, 6th International Conference on the Head and Neck Cancer Washington DC, U.S.A., 7-11 August 2004. |
| Wei W.I., Complications of snoring surgery, how to recognize, avoid and treat, Panel member of miniseminars, 108th Annual Meeting - American Academy of Otolaryngology Head and Neck Surgery, New York, USA, 19-22 September. 2004. |
| Wei W.I., Endoscopy assisted combined craniofacial resection for anterior skull base tumor-a critical appraisal, 2005 Beijing International Symposium of Rhinology & Skull Base Surgery, Beijing, China, 25 March. 2005. |
| Wei W.I., Funding for research and patient care in Hong Kong, Visit to University of Heidelberg, Faculty of Clinical Medicine Mannheim, Germany, 15 October 2004. 2004. |
| Wei W.I., Gastric pull up operation - techniques and results, International Comprehensive Head & Neck Course 2004, Nanchang, Jiangxi, China 27-28 November 2004. |
| Wei W.I., Honorary Member of Editorial Board (1999 - present), Chinese Journal of Cancer. 2005. |
| Wei W.I., Hypopharyngeal cancer: surgical management and reconstruction, 6th International Conference on the Head and Neck Cancer, Washington, U.S.A., 7 - 11 August. 2004. |
| Wei W.I., Laryngectomy for throid cancer involving the upper aerodigestive tract, 6th International Conference on the Head and Neck Cancer Washington DC, U.S.A., 7-11 August 2004. 2004. |
| Wei W.I., Management of recurrent nasopharyngeal cancer, Instructional Course, XVIII IFOS World Congress, Rome, Italy, 25-30 June. 2005. |
| Wei W.I. and Ho W.K., Management of the N0 neck-reference or preference (Epub ahead of print), Oral Oncology. Epub ahead of print, 2005, internet publication. |
| Wei W.I., Management of the cervical lymph nodes in head and neck cancer, International Comprehensive Head & Neck Course 2004, Nanchang, Jiangxi, China 27-28 November 2004. |
| Wei W.I., Maxillary Swing Approach to the Central Skull Base, Osaka University School of Medicine, Department of Otolaryngology & Sensory Organ Surgery, Osaka, Japan 24 May 2005. 2005. |
| Wei W.I., Maxillary Swing Approach to the Central Skull Base, Osaka University School of Medicine, Dept of Otolaryngology & Sensory Organ Surgery, Osaka, Japan, 24 May. 2005. |
| Wei W.I., Maxillary swing approach to central skull base, 4th SVO International Conference on Head and Neck Cancer Venice Mestre, Italy, 3-5 September. 2004. |
| Wei W.I., Maxillary swing approach, 4th SVO International Conference on Head and Neck Cancer, Venice Mestre, Italy, 3 - 5 September. 2004. |
| Wei W.I., Member of Editorial Board (1996 - present), Chinese Journal of Otolaryngology. 2005. |
| Wei W.I., Member of Editorial Board (2001 - 2004), Chinese Journal of Otorhinolaryngology - Skull Base Surgery. 2005. |
| Wei W.I., Member of Editorial Board (2001 - 2007), Head & Neck. 2005. |
| Wei W.I., Member of Editorial Board (January 1997 - present), Journal of Clinical Otorhinolaryngology (China). 2005. |
| Wei W.I., Member of Editorial Board (June 1995 - present), Australian and New Zealand Journal of Surgery. 2005. |
| Wei W.I., Member of Editorial Board (November 1994 - present), The American Journal of Otolaryngology. 2005. |
| Wei W.I., Member of Editorial Board (October 1995 - present), Chinese Journal of Clinical Oncology. 2005. |
| Wei W.I., Member of Editorial Board, The ASEAN ORL Head and Neck Journal. 2005. |
| Wei W.I., Nasopharyngeal Cancer, 6th International Conference on the Head and Neck Cancer Washington DC, U.S.A., 7-11 August 2004. |
| Wei W.I., Nasopharyngeal carcinoma fallacies and facts, Satellite symposium, 29th Annual Meeting of Japan Society for Head & Neck Cancer, Tokyo, Japan, 16 June . 2005. |
| Wei W.I. and Sham J.S.T., Nasopharyngeal carcinoma, Lancet. 2005, 365: 2041-2054. |
| Wei W.I., Nasopharyngectomy for central skull base lesions - a decade of experience, 108th Annual Meeting - American Academy of Otolaryngology Head and Neck Surgery, New York, U.S.A., 19 - 22 September. 2004. |
| Wei W.I., Nasopharyngectomy for central skull base lesions - a decade of experience, 4th International Skull Base Congress sydney, Australia 31 October - 4 November 2004 (invited). 2004. |
| Wei W.I., Nasopharyngectomy for central skull base lesions - a decade of experience, International Symposium on head and Neck Cancer, Memorial Sloan - Kettering Cancer Center New York, U.S.A. 23 September 2004. 2004. |
| Wei W.I., National Delegate, Newsletter Editor, International Federation of Head and Neck Oncologic Societies. 2005. |
| Wei W.I., Observer in the American Board of Otolaryngology Examination and Committee Meetings, Chicago, USA, 12 - 18 April. 2005. |
| Wei W.I., Otolaryngologists and managing patients with SARS, 108th Annual Meeting - American Academy of Otolaryngology Head and Neck Surgery, New York, U.S.A., 19 -22 September. 2004. |
| Wei W.I., Otolaryngologists managing Patients with Severe Acute Respiratory Syndrome (SARS), 108th Annual Meeting - American Academy of Otolaryngology Head and Neck Surgery, New York, USA,19-22 September. 2004. |
| Wei W.I. and Ho W.K., Palatal implant for snoring, Media Interview . Faculty of Medicine, the University of Hong Kongand Health columns in major Hong Kong newspapers and TV channels. Hong Kong, 2004. |
| Wei W.I., Panel Member on "Nasopharyngeal pathology and approaches", 4th International Skull Base Congress, Sydney, Australia, 31 October - 4 November . 2004. |
| Wei W.I., Parotidectomy - How I do it, 4th SVO International Conference on Head and Neck Cancer, Venice Mestre, Italy, 3 - 5 September. 2004. |
| Wei W.I., Past & Future - History of ENT in China & Hong Kong form Myth to Reality, Royal Society of Medicine Bicentenary Lecture London, U.K. 6 May 2005. |
| Wei W.I., Prevention of tracheostome stenosis following total laryngectomy, International Comprehensive Head & Neck Course 2004, Nanchang, Jiangxi, China 27-28 November 2004. |
| Wei W.I., Principle of surgical oncology, Diploma in Oncology and Palliative Care for Health Care Professionals, Hong Kong, 6 October. 2004. |
| Wei W.I., Yuen P.W., Ng W.M., Ho W.K., Kwong D.L.W. and Sham J.S.T., Quantitative analysis of plasma cell-free epstein-barr virus DNA in nasopharyngeal carcinoma after salvage nasopharyngectomy: a prospective study, Head & Neck. 2004, 26: 878-883. |
| Wei W.I., Reconstruction of the skull base following craniofacial resection, 2005 Beijing International Symposium of Rhinology & Skull Base Surgery, Beijing, China, 25 March. 2005. |
| Wei W.I., Reconstruction options in head and neck surgery, Recent Advances in Otolaryngology and Head & Neck Surgery - Satellite Symposium, Sapporo, Japan, 18 June. 2005. |
| Wei W.I. and Woolford T., Recurrent or persistent nasopharyngeal carcinoma following radiotherapy - diagnosis and salvage (How I do it), ENT News. 2005, 14(1): 74-77. |
| Wei W.I., Salvage neck dissection after radiation and/or chemotherapy, Operative Techniques in Otorhinolaryngology. 2004, 15: 269-272. |
| Wei W.I., Salvage surgery for recurrent head and neck cancer - technique and results, Hong Kong Surgical Forum - Hong Kong, 9 - 10 July. 2004. |
| Wei W.I., Speech rehabilitation after total laryngectomy, International Comprehensive Head & Neck Course 2004, Nanchang, Jiangxi, China 27-28 November 2004. |
| Wei W.I. and Ho W.K., Surgery for snoring, Medical Progress. 2004, 31: 538-542. |
| Wei W.I., Surgical Management of chronic aspiration, 10th Certificate Course in ENT Diseases for Nurses - Tung Wah Hospital, Hong Kong, 7 February. 2005. |
| Wei W.I., Surgical Salvage for Residual or Recurrent Nasopharyngeal Carcinoma Rationale, Reappraisal and Reality, 106th Annual Confreence, Japan Otorhinolarynogology Society Osaka, Japan 21 May 2005. 2005. |
| Wei W.I., Surgical management of hypopharynx cancer, 4th SVO International Conference on Head and Neck Cancer Venice Mestre, Italy, 3-5 September 2004. 2004. |
| Wei W.I., Surgical management of hypopharynx cancer, 4th SVO International Conference on Head and Neck Cancer, Venice Mestre, Italy, 3 - 5 September. 2004. |
| Wei W.I., Surgical specimen: source of solution, 20th Anniversary of the Korean Society of Head & Neck Oncology, Seoul, Korea 19-20 November. 2004. |
| Wei W.I., The evolution of mandibular reconstruction following advanced cancer resection in Hong Kong, Symposium, XVIII IFOS World Congress,Rome, Italy, 25-30 June . 2005. |
| Wei W.I., What have we learned from surgical specimens, 29th Annual Meeting of Japan Society for Head & Neck Cancer, Tokyo, Japan, 16 June. 2005. |
| Wei W.I., 亞洲無喉聯會的發展及現況, Visit to First Affiliated Hospital of Jiangxi Medical College, Nanchang, Jianxi, China, 24 - 27 August. 2004. |
| Wei W.I., 甲狀線腫瘤, Public Education Program, RTHK 22 February 2005. 2005. |
| Wei W.I., 頭頸部游離皮瓣的應用, 咽喉頭頸及喉癌喉功能手術全國學習班中華耳鼻咽喉頭頸外科雜誌編輯部, 廣州市耳鼻咽喉頭頸外科醫院主辦, 6 June 2005, 2005. |
| Wong T.S., Kwong D.L.W., Sham J.S.T., Wei W.I., Kwong Y.L. and Yuen P.W., Elevation of plasma osteopontin level in patients with undifferentiated nasopharyngeal carcinoma, European Journal of surgical Oncology. 2005, 31: 555-558. |
| Wong Y.K., Hui Y., Au D.K.K., Jin H. and Wei W.I., 人工耳蝸植入術的經濟學價值, Chinese Journal of Otorhinolaryngology. 2004, 39(12): 755-756. |
| 熒 ......, 陳 伊.寧., 農 輝.圖., 唐 安.洲., 徐 志.文., 莫 福.琴., 宋 斌. and Wei W.I., 全喉切除術後无喉者的語言康復實踐, 臨床耳鼻咽喉科雜誌, 2004, 18(7): 437-438. |
| Researcher : Wo YH |
| List of Research Outputs |
| Ng K.K.C., Lam C.M., Poon R.T.P., Shek T.W.H., To J.Y.T., Wo Y.H., Ho D.W.Y. and Fan S.T., Comparison of systemic responses of radiofrequency ablation, cryotherapy, and surgical resection in a porcine liver model, Annals of Surgical Oncology. 2004, 11(7): 650-657. |
| Ng K.K.C., Lam C.M., Poon R.T.P., Shek T.W.H., Yu W.C., To J.Y.T., Wo Y.H., Lau C.P.Y., Tang T.C.M., Ho D.W.Y. and Fan S.T., Porcine liver: morphological characteristics and cell viability at experimental radiofrequency ablation with internally cooled electrodes, Radiology. 2005, 235(2): 478-486. |
| Researcher : Wong J |
| Project Title: | Thoracoscopic cardiomyotomy for achalasia |
| Investigator(s): | Wong J, Law SYK |
| Department: | Surgery |
| Source(s) of Funding: | Other Funding Scheme |
| Start Date: | 01/1994 |
| Abstract: |
| To study the efficacy of a new approach of surgical treatment for achalasia, using endoscopic instruments via tiny incisions into the thoracic cavity, thus avoiding the complications and discomforts if long surgical incision from traditional surgical approach. |
| Project Title: | Randomised prospective trial comparing the use of neck drain after oesophagectomy with cervical anastomosis |
| Investigator(s): | Wong J, Law SYK |
| Department: | Surgery |
| Source(s) of Funding: | Other Funding Scheme |
| Start Date: | 01/1994 |
| Abstract: |
| To evaluate the need of routine cervical drains after oesophagectomy. |
| Project Title: | Randomised prospective trial investigating the effect of preoperative chemo-radiation for resectable carcinoma of the oesophagus |
| Investigator(s): | Wong J, Law SYK |
| Department: | Surgery |
| Source(s) of Funding: | Other Funding Scheme |
| Start Date: | 01/1995 |
| Abstract: |
| To evaluate the use of preoperative chemo-radiation for treatment of oesophageal cancer. |
| Project Title: | Retrospective and prospective study on the use of chemotherapy and chemoradiotherapy in the treatment of recurrent disease after oesophagectomy for cancer |
| Investigator(s): | Wong J, Law SYK |
| Department: | Surgery |
| Source(s) of Funding: | Other Funding Scheme |
| Start Date: | 01/1995 |
| Abstract: |
| To evaluate the use of chemotherapy and spare chemoradiotherapy in the treatment of recurrent disease. |
| Project Title: | Prospective study of the use of chemoradiotherapy in the treatment of advanced carcinoma of the oesophagus not suitable for resection |
| Investigator(s): | Wong J, Law SYK |
| Department: | Surgery |
| Source(s) of Funding: | Other Funding Scheme |
| Start Date: | 01/1995 |
| Abstract: |
| To evaluate the use of chemoradiotherapy in the treatment of advanced carcinoma of the oesophagus not suitable for resection. |
| Project Title: | Thoracoscopic oesophagectomy for carcinoma of the oesophagus |
| Investigator(s): | Wong J, Law SYK |
| Department: | Surgery |
| Source(s) of Funding: | Other Funding Scheme |
| Start Date: | 04/1996 |
| Abstract: |
| To study the efficacy of an endoscopic approach in the resection of oesophageal carcinoma without the necessity of a conventional open thoracotomy. This would have the benefit of decreasing the incidence of pulmonary complications and deaths related to these complications associated with conventional surgery. Thoracoscopic oesophagectomy will also be compared with the transhiatal approach to see whether there are differences in morbidit, mortality and survival. |
| Project Title: | The use of endoscopic ultrasound in staging of esophageal cancer |
| Investigator(s): | Wong J, Chu KM, Law SYK |
| Department: | Surgery |
| Source(s) of Funding: | Other Funding Scheme |
| Start Date: | 07/1996 |
| Abstract: |
| To evaluate the accuracy and use of endoscopic ultrasound in the management of esophageal cancer. |
| Project Title: | Clinical significance of hepatocyte growth factor in esophageal squamous cell carcinoma |
| Investigator(s): | Wong J, Law SYK, Ren Y |
| Department: | Surgery |
| Source(s) of Funding: | Small Project Funding |
| Start Date: | 11/2003 |
| Abstract: |
| To investigate whether relationships exist between serum HGF levels and angiogenic factors, clinico- pathological factors, and long-term survival; to study whether HGF correlates with angiogenic factors such as VEGF and IL-8 in patients' sera; to detect the possible sources of HGF in ESCC specimens. |
| List of Research Outputs |
| Fatima S., Hui K.S., Wong M.M., Tang W.K., Chui C.H., Wong J., Law S.Y.K., Tsao G.S.W., Lam K.Y., Srivastava G., Ho K.P. and Tang J.C.O., Study of transforming capacity of two novel genes JS-1 and JS-2 in chromosome 5p and their overexpression in human esophageal squamous cell carcinoma, 96th Annual Meeting of the American Association for Cancer Research, Anaheim, California, USA, 16-20 April. 2005. |
| Ferri L.E., Lee J.K.T., Law S.Y.K., Wong K.H., Kwok K.F. and Wong J., Management of spontaneous perforation of esophageal cancer with covered self expanding metallic stents (Case Report), Diseases of the Esophagus. 2005, 18(1): 67-69. |
| Ferri L.E., Law S.Y.K., Wong K.H., Kwok K.F. and Wong J., The impact of technical complications on short term adverse outcomes and survival after esophagectomy (Abstract), 19th World Congress of International Society for Digestive Surgery, Yokohama, Japan, 8-11 December. 2004. |
| Ferri L.E., Law S.Y.K., Wong K.H., Kwok K.F. and Wong J., The impact of technical complications on short term adverse outcomes and survival after esophagectomy (Abstract), Journal of Gastrointestinal Surgery. 2004, 8(Supplement 7S): 76A. |
| Ko S., Chu K.M., Luk J.M.C., Wong W.Y., Yuen S.T., Leung S.Y. and Wong J., CDX2 co-localizes with liver-intestine cadherin in intestinal metaplasia and adenocarcinoma of stomach, Journal of Pathology . 2005, 205: 615-622. |
| Lang B.H.H., Poon R.T.P., Fan S.T. and Wong J., Outcomes of patients with hepatocellular carcinoma presenting with variceal bleeding, American Journal of Gastroenterology. 2004, 99(11): 2158-2165. |
| Law S.Y.K., Suen D.T.K., Wong K.H., Kwok K.F. and Wong J., A single-layer, continuous, hand-sewn method for esophageal anastomosis - prospective evaluation in 218 patients, Archives of Surgery. 2005, 140(1): 33-39. |
| Law S.Y.K. and Wong J., Complications of esophageal resection: not preventable but not fatal (Abstract), 59th Annual Meeting of the Japanese Society of Gastroenterological Surgery, Kagoshima, Japan, 21-23 July. 2004. |
| Law S.Y.K. and Wong J., Complications of esophageal resection: not preventable but not fatal (Abstract), The Japanese Journal of Gastroenterological Surgery. 2004, 37(7): 195. |
| Law S.Y.K. and Wong J., Current management of esophageal cancer (Review Article), Journal of Gastrointestinal Surgery. 2005, 9(2): 291-310. |
| Law S.Y.K. and Wong J., Current status of esophageal cancer treatment in Asia, Esophagus. 2004, 1(4): 169-176. |
| Law S.Y.K. and Wong J., Esophageal cancer surgery: lessons from 1,200 resections, Hawaii Medical Journal. 2004, 63(7): 203-205. |
| Law S.Y.K., Kwong D.L.W., Wong K.H., Kwok K.F., Sham J.S.T. and Wong J., Oesophageal cancer located above the tracheal bifurcation is an independent poor prognostic factor. Neoadjuvant chemoradiation improves survival (Abstract), Gut. 2004, 53 (Supplement VI): A279-A280. |
| Law S.Y.K., Kwong D.L.W., Wong K.H., Kwok K.F., Sham J.S.T. and Wong J., Oesophageal cancer located above the tracheal bifurcation is an independent poor prognostic factor. Neoadjuvant chemoradiation improves survival (Abstract), The 12th United European Gastroenterology Week, Prague, Czech Republic, 25-29 September. 2004. |
| Law S.Y.K., Wong K.H., Kwok K.F., Chu K.M. and Wong J., Predictive factors for postoperative pulmonary complications and mortality after esophagectomy for cancer, Annals of Surgery. 2004, 240(5): 791-800. |
| Leung S.Y., Yuen S.T., Chu K.M., Mathy J.A., Li R., Chan A.S.Y., Law S.Y.K., Wong J., Chen X. and So S., Expression profiling identifies chemokine (C-C motif) ligand 18 as an independent prognostic indicator in gastric cancer, Gastroenterology. 2004, 127(2): 457-469. |
| Lin C.L., Fan S.T., Lo C.M. and Wong J., The role of endoscopic ultrasonography in the management of acute pancreatitis: a prospective randomized study (Invited Lecture), The 12th United European Gastroenterology Week, Prague, Czech Republic, 25-29 September 2004. |
| Liu C.L., Fan S.T., Lo C.M. and Wong J., Clinicobiochemical prediction of biliary cause for acute pancreatitis in the era of endoscopic ultrasonography (Poster Presentation), The 12th United European Gastroenterology Week, Prague, Czech Republic, 25-29 September 2004. |
| Liu C.L., Fan S.T., Lo C.M., Chan S.C., Tso W.K., Ng I.O.L. and Wong J., Hepatic resection for incidentaloma, Journal of Gastrointestinal Surgery. 2004, 8(7): 785-793. |
| Liu C.L., Fan S.T., Lo C.M., Tso W.K. and Wong J., Improved operative and survival outcomes of surgical treatment for hilar cholangiocarcinoma (Abstract), HPB. 2005, 7(1 Suppl): 129. |
| Liu C.L., Fan S.T., Lo C.M., Tso W.K. and Wong J., Improved operative and survival outcomes of surgical treatment for hilar cholangiocarcinoma (Invited Lecture), The 6th Congress of the European Hepato-Pancreato-Biliary Association, Heidelberg, Germany, 25-28 May 2005. |
| Liu C.L., Fan S.T., Lo C.M., Wei W.I., Chan S.C., Yong B.H., Lai C.L. and Wong J., Operative outcomes of adult-to-adult right lobe live donor liver transplantation: a comparative study with cadaveric whole-graft liver transplantation in a single center (Abstract), The 20th International Congress of the Transplantation Society, Vienna, Austria, 5-10 September 2004. |
| Liu C.L., Fan S.T., Lo C.M., Chan S.C., Yong B.H. and Wong J., Safety of donor right hepatectomy without abdominal drainage: a prospective evaluation in 100 consecutive liver donors, Liver Transplantation. 2005, 11(3): 314-319. |
| Lo C.M., Fan S.T., Liu C.L., Yong B.H., Wong Y., Lau G., Lai C.L., Ng I.O.L. and Wong J., Lessons learned from one hundred right lobe living donor liver transplants, Annals of Surgery. 2004, 240(1): 151-158. |
| Lo C.M., Liu C.L., Lau G., Chan S.C., Ng I.O.L., Fan S.T. and Wong J., Liver transplantation for chronic hepatitis B with lamivudine-resistant YMDD mutant using add-on adefovir dipivoxil to lamivudine (Abstract), American Journal of Transplantation. 2005, 5(Suppl): 180. |
| Lo C.M., Liu C.L., Lau G., Chan S.C., Ng I.O.L., Fan S.T. and Wong J., Liver transplantation for chronic hepatitis B with lamivudine-resistant YMDD mutant using add-on adefovir dipivoxil to lamivudine (Poster Presentation), American Transplant Congress, Seattle, U.S.A., 21-25 May 2005. |
| Lo C.M., Fan S.T., Liu C.L., Chan S.C., Ng I.O.L. and Wong J., Living donor versus deceased donor liver transplantation for early unresectable hepatocellular carcinoma: same criteria, different outcome (Abstract), HPB. 2005, 7(1 Suppl): 54. |
| Lo C.M., Fan S.T., Liu C.L., Chan S.C., Ng I.O.L. and Wong J., Living donor versus deceased donor liver transplantation for early unresectable hepatocellular carcinoma: same criteria, different outcome (Invited Lecture), The 6th Congress of the European Hepato-Pancreato-Biliary Association, Heidelberg, Germany, 25-28 May 2005. |
| Lo C.M., Fan S.T. and Wong J., Living donor versus deceased donor liver transplantation for early unresectable hepatocellular carcinoma: same criteria, different outcome (Poster Presentation), Digestive Disease Week, Chicago, U.S.A., 14-19 May 2005. |
| Lo C.M., Fan S.T., Liu C.L., Chan S.C., Ng I.O.L. and Wong J., Living donor versus deceased donor liver transplantation for small unresectable hepatocellular carcinoma: same criteria, different outcome (Invited Lecture), The 6th Annual Scientific Meeting, Centre for the Study of Liver Disease, The University of Hong Kong, Hong Kong, 8 January 2005. |
| Luo Y., Lo C.M., Cheung C.K.Y., Lau G., Fan S.T. and Wong J., Potential role of resident intrahepatic lymphocytes in adoptive transfer of immunity to hepatitis B virus through liver transplantation (Poster Presentation), Digestive Disease Week, Chicago, U.S.A., 14-19 May 2004. |
| Mok V.W.K., Ting A.C.W., Law S.Y.K., Wong K.H., Cheng S.W.K. and Wong J., Combined endovascular stent grafting and endoscopic injection of fibrin sealant for aortoenteric fistula complicating esophagectomy, Journal of Vascular Surgery. 2004, 40(6): 1234-1237. |
| Poon R.T.P., Fan S.T., Lo C.M., Liu C.L., Lam C.M., Yuen W.K., Yeung C. and Wong J., Improving perioperative outcome expands the role of hepatectomy in management of benign and malignant hepatobiliary diseases: analysis of 1222 consecutive patients from a prospective database, Annals of Surgery. 2004, 240(4): 698-708. |
| Poon R.T.P., Fan S.T. and Wong J., Liver resection using a saline-linked radiofrequency dissecting sealer for transection of the liver, Journal of the American College of Surgeons. 2005, 200(2): 308-313. |
| Ren Z., Borody T., Pang G., Dunkley M., Clancy R., Xia H.H.X., Chu K.M., Wong J. and Wong B.C.Y., Evaluation of anti-Helicobacter pylori IgG2 antibody for the diagnosis of Helicobacter pylori infection in Western and Chinese populations, Alimentary Pharmacology & Therapeutics. 2005, 21: 83-89. |
| Wong J., A surgical skills lab in Hong Kong, 122. Kongress der Deutschen Gesellschaft fur Chirurgie, Munich, Germany, 5-8 April. 2005. |
| Wong J., Complications of esophagectomy: confess and remember, 10th Annual W. B. & M. H. Chung Lecture 2004, Department of Surgery, University of British Columbia, Vancouver, Canada, 29 October. 2004. |
| Wong J., Esophageal cancer - best treatment (Special Symposium), 59th Annual Meeting of the Japanese Society of Gastroenterological Surgery, Kagoshima, Japan, 21-23 July. 2004. |
| Wong J., Esophageal cancer worldwide: same name, different diseases, one mission, Distinguished Lecture of the International Society of Surgery, Clinical Congress of American College of Surgeons, New Orleans, USA, 10-14 October. 2004. |
| Wong J., Hong Kong, China (Dinner Talk), 10th Annual W. B. & M. H. Chung Lectureship 2004, Research Day, Department of Surgery, University of British Columbia, St. Paul's Hospital, Vancouver, Canada, 29 October. 2004. |
| Wong J., Member of Editorial Board, Advances in Surgery. 2005. |
| Wong J., Member of Editorial Board, Australian & New Zealand Journal of Surgery. 2005. |
| Wong J., Member of Editorial Board, Chinese Journal of Clinical Oncology. 2005. |
| Wong J., Member of Editorial Board, Chinese Journal of Gastrointestinal Surgery. 2005. |
| Wong J., Member of Editorial Board, Clinics in Surgery and Gastroenterology. 2005. |
| Wong J., Member of Editorial Board, Croatian Journal of Gastroenterology and Hepatology. 2005. |
| Wong J., Member of Editorial Board, Current Practice in Surgery. 2005. |
| Wong J., Member of Editorial Board, Digestive Surgery. 2005. |
| Wong J., Member of Editorial Board, Diseases of the Esophagus. 2005. |
| Wong J., Member of Editorial Board, Hepato-Gastroenterology. 2005. |
| Wong J., Member of Editorial Board, International Journal of Clinical Oncology. 2005. |
| Wong J., Member of Editorial Board, Italian Journal of Gastroenterology. 2005. |
| Wong J., Member of Editorial Board, Journal of Clinical Oncology (Chinese edition). 2005. |
| Wong J., Member of Editorial Board, Journal of Gastroenterology & Hepatology. 2005. |
| Wong J., Member of Editorial Board, Journal of the American College of Surgeons. 2005. |
| Wong J., Member of Editorial Board, Journal of the Spanish Surgical Association (Cirugia Espanola). 2005. |
| Wong J., Member of Editorial Board, Surgery. 2005. |
| Wong J., Member of Editorial Board, The Journal of Gastrointestinal Surgery. 2005. |
| Wong J., Member of Editorial Board, The Lancet Oncology. 2005. |
| Wong J., Member of Editorial Board, WebSurg. 2005. |
| Wong J., Progress in esophageal surgery: "the search for perfection", 122. Kongress der Deutschen Gesellschaft fur Chirurgie, Munich, Germany, 5-8 April. 2005. |
| Wong J., Resection of gastrointestinal cancers: in search of perfection, Edward Hallaran Bennett Lecture, Trinity College, Dublin, Ireland, 17 November. 2004. |
| Researcher : Wong KKY |
| List of Research Outputs |
| Lan L.C.L., Lin C.L., Wong K.K.Y. and Tam P.K.H., Parenteral nutrition is a major risk factor for children undergoing central venous catheterization, 38th Annual Meeting of the Pacific Association of Pediatric Surgery, Vancouver, Canada, 22-26 May 2005. |
| Lan L.C.L., Lee K.K., Lin C.L., Wong K.K.Y. and Tam P.K.H., Placement of percutaneous endoscopic gastrostomy in children with ventriculoperitoneal shunt, 38th Annual Meeting of the Pacific Association of Pediatric Surgery, Vancouver, Canada, 22-26 May 2005. |
| Wong K.K.Y., Fan A.H., Lan L.C.L., Lin C.L. and Tam P.K.H., Effective antibiotic regime for postoperative acute cholangitis in biliary atresia - an evolving scene, Journal of Pediatric Surgery. 2004, 39(12): 1800-1802. |
| Wong K.K.Y., Lan L.C.L., Yip P.K.F. and Tam P.K.H., Laparoscopic resection of tracheobronchial remnants causing congenital esophageal stenosis, 38th Annual Meeting of the Pacific Association of Pediatric Surgery, Vancouver, Canada, 22-26 May 2005. |
| Wong K.K.Y., Lan L.C.L., Lin C.L., Chan A.W.S. and Tam P.K.H., Mucous fistula refeeding in premature neonates with enterostomies, Journal of Pediatric Gastroenterology and Nutrition. 2004, 39: 43-45. |
| Wong K.K.Y., Khong P.L., Lin C.L., Lam W.W.M., Lan L.C.L. and Tam P.K.H., Post-operative magnetic resonance evaluation of children after laparoscopic anorectoplasty for imperforate anus, International Journal of Colorectal Disease. 2005, 20(1): 33-37. |
| Wong K.K.Y. and Tam P.K.H., Press release - Laparoscopic-assisted Rectoanoplasty for Imperforate Anus, 2004. |
| Wong K.K.Y., Wong J.S.W., Lan L.C.L. and Tam P.K.H., Setting up a laparoscopic surgical service: experience in an Asian paediatric surgical unit, 19th Congress of the Asian Association of Paediatric Surgeons, Hong Kong, 28 November - 1 December 2004. |
| Wong K.K.Y., Lan L.C.L., Lin C.L. and Tam P.K.H., Superior mesenteric artery syndrome: are we over-diagnosing in children?, 19th Congress of the Asian Association of Paediatric Surgeons, Hong Kong, 28 November - 1 December 2004. |
| Wong K.K.Y., Lan L.C.L., Lin C.L. and Tam P.K.H., The electronic surgical unit: a stride into the 21st century, 19th Congress of the Asian Association of Paediatric Surgeons, Hong Kong, 28 November - 1 December 2004. |
| Wong K.K.Y., Lan L.C.L., Lin C.L. and Tam P.K.H., The use of positron emission tomography in detecting hepatoblastoma recurrence - a cautionary tale, Journal of Pediatric Surgery. 2004, 39(12): 1779-1781. |
| Wong K.K.Y., Chung P.H.Y., Lan L.C.L., Lin C.L. and Tam P.K.H., Trends in the prevalence of H. pylori in symptomatic children in the era of eradication, 38th Annual Meeting of the Pacific Association of Pediatric Surgery, Vancouver, Canada, 22-26 May 2005. |
| Researcher : Wong SY |
| List of Research Outputs |
| Chan H.H.L., Wong S.Y., Ho W.S., Lam L.K. and Wei W.I., The use of pulsed dye laser for the prevention and treatment of hypertrophic scars in Chinese persons, Dermatologic Surgery. 2004, 30: 987-994. |
| Cheung S.T., Leung K.L., Kwok H.H., Wong S.Y. and Fan S.T., DNALI1 expression and gene polymorphism are associated with disease recurrence after curative surgery in hepatocellular carcinoma (Abstract), The 96th Annual Meeting of the American Association for Cancer Research, Anaheim, California, U.S.A., 16-20 April 2005. |
| Cheung S.T., Wong S.Y., Leung K.L., Chen X., So S., Ng I.O.L. and Fan S.T., Granulin-epithelin precursor (GEP) promotes growth and invasion of hepatocellular carcinoma (Abstract), The 6th Annual Scientific Meeting, Centre for the Study of Liver Disease, The University of Hong Kong, Hong Kong, 8 January 2005. |
| Cheung S.T., Wong S.Y., Leung K.L., Chen X., So S., Ng I.O.L. and Fan S.T., Granulin-epithelin precursor overexpression promotes growth and invasion in hepatocellular carcinoma, Clinical Cancer Research. 2004, 10(22): 7629-7636. |
| Hui Y., Wong S.Y., Ho W.K. and Wei W.I., (2) OT 43 A prospective controlled double-blind trial of great auricular nerve preservation at parotidectomy. Am J Surg. 2003 Jun;185(6):574-9, In: Paparella MM, Otto RA, Keefe MA, Year Book of Otolaryngology-Head and Neck Surgery 2004. Mosby, 2004, (2) OT 43. |
| Wong S.Y., Council member, Hong Kong College of Surgeons, The Hong Kong Academy of Medicine. 2005. |
| Wong S.Y., Reviewer, Asian Journal of Surgery. 2005. |
| Wong S.Y., Secretary, Second Conference in Dermatological Laser and Facial Cosmetic Surgery 2006. 2005. |
| Researcher : Wong SY |
| List of Research Outputs |
| Chan H.H.L., Wong S.Y., Ho W.S., Lam L.K. and Wei W.I., The use of pulsed dye laser for the prevention and treatment of hypertrophic scars in Chinese persons, Dermatologic Surgery. 2004, 30: 987-994. |
| Cheung S.T., Leung K.L., Kwok H.H., Wong S.Y. and Fan S.T., DNALI1 expression and gene polymorphism are associated with disease recurrence after curative surgery in hepatocellular carcinoma (Abstract), The 96th Annual Meeting of the American Association for Cancer Research, Anaheim, California, U.S.A., 16-20 April 2005. |
| Cheung S.T., Wong S.Y., Leung K.L., Chen X., So S., Ng I.O.L. and Fan S.T., Granulin-epithelin precursor (GEP) promotes growth and invasion of hepatocellular carcinoma (Abstract), The 6th Annual Scientific Meeting, Centre for the Study of Liver Disease, The University of Hong Kong, Hong Kong, 8 January 2005. |
| Cheung S.T., Wong S.Y., Leung K.L., Chen X., So S., Ng I.O.L. and Fan S.T., Granulin-epithelin precursor overexpression promotes growth and invasion in hepatocellular carcinoma, Clinical Cancer Research. 2004, 10(22): 7629-7636. |
| Hui Y., Wong S.Y., Ho W.K. and Wei W.I., (2) OT 43 A prospective controlled double-blind trial of great auricular nerve preservation at parotidectomy. Am J Surg. 2003 Jun;185(6):574-9, In: Paparella MM, Otto RA, Keefe MA, Year Book of Otolaryngology-Head and Neck Surgery 2004. Mosby, 2004, (2) OT 43. |
| Wong S.Y., Council member, Hong Kong College of Surgeons, The Hong Kong Academy of Medicine. 2005. |
| Wong S.Y., Reviewer, Asian Journal of Surgery. 2005. |
| Wong S.Y., Secretary, Second Conference in Dermatological Laser and Facial Cosmetic Surgery 2006. 2005. |
| Researcher : Wong TS |
| List of Research Outputs |
| Wong T.S., A study of gene methylation in head and neck cancer, Thesis, Doctor of Philosophy, The University of Hong Kong. 2005. |
| Wong T.S., Kwong D.L.W., Sham J.S.T., Wei W.I., Kwong Y.L. and Yuen P.W., Elevation of plasma osteopontin level in patients with undifferentiated nasopharyngeal carcinoma, European Journal of surgical Oncology. 2005, 31: 555-558. |
| Researcher : Wong TS |
| List of Research Outputs |
| Wong T.S., A study of gene methylation in head and neck cancer, Thesis, Doctor of Philosophy, The University of Hong Kong. 2005. |
| Wong T.S., Kwong D.L.W., Sham J.S.T., Wei W.I., Kwong Y.L. and Yuen P.W., Elevation of plasma osteopontin level in patients with undifferentiated nasopharyngeal carcinoma, European Journal of surgical Oncology. 2005, 31: 555-558. |
| Researcher : Wong WY |
| List of Research Outputs |
| Ko S., Luk J.M.C., Wong W.Y., Leung S.Y. and Chu K.M., CDX2 co-localizes with liver-intestine cadherin in intestinal metaplasia and adenocarcinoma of stomach, 6th International Gastric Cancer of Congress, Yokohama, Japan, 4-7 May 2005. |
| Ko S., Chu K.M., Luk J.M.C., Wong W.Y., Yuen S.T., Leung S.Y. and Wong J., CDX2 co-localizes with liver-intestine cadherin in intestinal metaplasia and adenocarcinoma of stomach, Journal of Pathology . 2005, 205: 615-622. |
| Wang X., Luk J.M.C., Leung P.L., Wong W.Y., Stanbridge E.J. and Fan S.T., Alternative mRNA splicing of liver intestine-cadherin in hepatocellular carcinoma, Clinical Cancer Research. 2005, 11(2 Pt 1): 483-489. |
| Researcher : Wong WY |
| List of Research Outputs |
| Ko S., Luk J.M.C., Wong W.Y., Leung S.Y. and Chu K.M., CDX2 co-localizes with liver-intestine cadherin in intestinal metaplasia and adenocarcinoma of stomach, 6th International Gastric Cancer of Congress, Yokohama, Japan, 4-7 May 2005. |
| Ko S., Chu K.M., Luk J.M.C., Wong W.Y., Yuen S.T., Leung S.Y. and Wong J., CDX2 co-localizes with liver-intestine cadherin in intestinal metaplasia and adenocarcinoma of stomach, Journal of Pathology . 2005, 205: 615-622. |
| Wang X., Luk J.M.C., Leung P.L., Wong W.Y., Stanbridge E.J. and Fan S.T., Alternative mRNA splicing of liver intestine-cadherin in hepatocellular carcinoma, Clinical Cancer Research. 2005, 11(2 Pt 1): 483-489. |
| Researcher : Wong Wu LH |
| List of Research Outputs |
| Ting A.C.W., Cheng S.W.K., Ho P., Poon J.T.C., Wong Wu L.H. and Cheung G.C.Y., Surgical treatment for advanced chronic venous insufficiency in Hong Kong, Annals of the College of Surgeons of Hong Kong. 2004, 8(4): 135-140. |
| Ting A.C.W., Cheng S.W.K., Ho P., Poon J.T.C., Wong Wu L.H. and Cheung G.C.Y., Surgical treatment of advanced chronic venous insufficiency in Hong Kong, Second Chinese Venous Forum, Shanghai, China, 4-5 June 2005. 2005. |
| Researcher : Xia F |
| List of Research Outputs |
| Poon R.T.P., Xia F. and Fan S.T., 原發性肝癌的治療原則, In: 芮靜安, 現代癌診斷治療學, 清華大學出版社, 2004, 205-220. |
| Researcher : Xie Y |
| List of Research Outputs |
| Ren Y., He Q., Fan J.Q., Jones B., Zhou Y., Xie Y., Cheung C.Y., Wu A.Y.Y., Chiu J., Peiris J.S.M. and Tam P.K.H., The use of proteomics in the discovery of serum biomarkers from patients with severe acute respiratory syndrome, Proteomics. 2004, 4: 3477-3484. |
| Researcher : Xu R |
| Project Title: | Oral gene therapy of tumors by using recombinant AAV-TRAIL viral vectors |
| Investigator(s): | Xu R, Kung H |
| Department: | Institute of Molecular Biology |
| Source(s) of Funding: | Matching Fund for Hi-Tech Research and Development Program of China (863 Projects) |
| Start Date: | 05/2002 |
| Abstract: |
| To study tumor therapy by using recombinant AAV. |
| Project Title: | Peroral transduction of hepatocytes for diabetes gene therapy |
| Investigator(s): | Xu R, Lam KSL |
| Department: | Institute of Molecular Biology |
| Source(s) of Funding: | Competitive Earmarked Research Grants (CERG) |
| Start Date: | 10/2002 |
| Abstract: |
| A major goal of gene therapy for Diabetes Mellitus (DM) is to restore long-term euglycemia. This study shall focus on clarifying the adeno-associated virus (AAV) vector transportation pathway from stomach to liver after oral administration. The research team will extend their previous study further to develop chimeric glucose- and insulin-sensitive promoters and insert them into the existing AAV vector system. |
| Project Title: | Preclinical study of lung cancer therapy using recombinant adeno-associate virus vector |
| Investigator(s): | Xu R |
| Department: | Institute of Molecular Biology |
| Source(s) of Funding: | Matching Fund for Hi-Tech Research and Development Program of China (863 Projects) |
| Start Date: | 04/2003 |
| Abstract: |
| To carrry out preclinical study of lung cancer therapy using recombinant adeno-associate virus vector. |
| Project Title: | Functional characterization of STAP gene and its potential use for gene therapy in liver cirrhosis, a leading cause of death and disability |
| Investigator(s): | Xu R, Fung PCW, Obara M., Yoshizato K. |
| Department: | Institute of Molecular Biology |
| Source(s) of Funding: | Incentive Award for RGC CERG Fundable But Not Funded Projects |
| Start Date: | 07/2003 |
| Abstract: |
| To determine the effects of STAP on oxidative stress during the progress of liver cirrhosis; to identify the signaling pathway by which STAP affects oxidative stress; to determine the efficiency of STAP in scavenging of radical-derived organic peroxides; to establish a gene therapy animal model to prevent liver cirrhosisusing STAP as a therapeutic gene; to establish a gene therapy animal model to treat liver cirrhosis using STAP as a therapeutic gene. |
| Project Title: | Cirrhosis: New appraoch provides a basis for targeted treatment |
| Investigator(s): | Xu R |
| Department: | Institute of Molecular Biology |
| Source(s) of Funding: | Incentive Award for RGC CERG Fundable But Not Funded Projects |
| Start Date: | 07/2004 |
| Abstract: |
| Refer to hard copy |
| List of Research Outputs |
| Researcher : Xu S |
| List of Research Outputs |
| Sun X., Krissansen G.W., Fung P.C.W., Xu S., Shi J., Man K., Fan S.T. and Xu R., Anti-angiogenic therapy subsequent to adeno-associated-virus-mediated immunotherapy eradicates lymphomas that disseminate to the liver, International Journal of Cancer. 2004, 113(4): 670-677. |
| Researcher : Xu X |
| List of Research Outputs |
| Lin X., Xu X., Huang Q.L., Liu Y., Zheng D.L., Chen W.N. and Lin J.Y., Biological impacts of the "hot-spot" mutations on hepatitis B virus X proteins are genotype B and C differentiated, World Journal of Gastroenterology. 2005, 11(30): 4703-4708. |
| Researcher : Yang Z |
| List of Research Outputs |
| Ho D.W.Y., Yang Z., Lau C.K., To J.Y.T., Luk J.M.C. and Fan S.T., The therapeutic role of cardiotrophin-1 in a rat model with fulminant hepatic failure (Abstract), The 6th Annual Scientific Meeting, Centre for the Study of Liver Disease, The University of Hong Kong, Hong Kong, 8 January 2005. |
| Ng S.S., Gao Y., Lum C.T., Yang Z., Huang J., Lau G., Fan S.T., Kung H. and Lin M.C., Novel HCC gene therapy by rAAV-mediated transfer of human TERTC27 polypeptide in human and rat hepatocellular carcinoma (Abstract), Asian Journal of Surgery. 2005, 28(Suppl 2): S99. |
| Ng S.S., Gao Y., Lum C.T., Yang Z., Huang J., Lau G., Fan S.T., Kung H. and Lin M.C., Novel HCC gene therapy by rAAV-mediated transfer of human TERTC27 polypeptide in human and rat hepatocellular carcinoma (Abstract), The 4th International Meeting on Hepatocellular Carcinoma: Eastern and Western Experiences, Hong Kong, 14-16 December 2004. |
| Ng S.S., Gao Y., Lum C.T., Yang Z., Lau G., Fan S.T., Kung H. and Lin M.C., rAAV-mediated long-term expression of endostatin significantly inhibits the progression of HCC (Abstract), Asian Journal of Surgery. 2005, 28(Suppl 2): S100. |
| Ng S.S., Gao Y., Lum C.T., Yang Z., Lau G., Fan S.T., Kung H. and Lin M.C., rAAV-mediated long-term expression of endostatin significantly inhibits the progression of HCC (Abstract), The 4th International Meeting on Hepatocellular Carcinoma: Eastern and Western Experiences, Hong Kong, 14-16 December 2004. |
| Poon R.T.P., Yang Z., Liu Y., Ho D.W.Y., Lau C.K. and Fan S.T., Blockade of vascular endothelial growth factor (VEGF) receptor enhances the therapeutic efficacy and chemotherapy in hepatocellular carcinoma (Abstract), The 96th Annual Meeting of the American Association for Cancer Research, Anaheim, California, U.S.A., 16-20 April 2005. |
| Yang Z., Ho D.W.Y., Lam C.T., Luk J.M.C., Lum C.T., Yu W.C., Poon R.T.P. and Fan S.T., Identification of brain-derived neurotrophic factor (BDNF) as a potential therapeutic target in hepatocellular carcinoma (Abstract), The 4th International Meeting on Hepatocellular Carcinoma: Eastern and Western Experiences, Hong Kong, 14-16 December 2004. |
| Yang Z., Ho D.W.Y., Lam C.T., Luk J.M.C., Yu W.C., Lo C.M., Poon R.T.P. and Fan S.T., Identification of brain-derived neurotrophic factor (BDNF) in hepatocellular carcinoma - from animal study to clinical management (Abstract), The 6th Annual Scientific Meeting, Centre for the Study of Liver Disease, The University of Hong Kong, Hong Kong, 8 January 2005. |
| Yang Z., Ho D.W.Y., Lam C.T., Luk J.M.C., Lum C.T., Yu W.C., Poon R.T.P. and Fan S.T., Identification of brain-derived neurotrophic factor as a novel functional protein in hepatocellular carcinoma, Cancer Research. 2005, 65(1): 219-225. |
| Yang Z., Ho D.W.Y., Lam C.T., Luk J.M.C., Poon R.T.P. and Fan S.T., The potential role of allograft inflammatory factor 1 (AIF-1) in macrophage activation in small-for-size liver transplantation, The 20th International Congress of the Transplantation Society, Vienna, Austria, 5-10 September 2004. |
| Yang Z., Poon R.T.P., To J.Y.T., Ho D.W.Y. and Fan S.T., The potential role of hypoxia inducible factor 1a in tumor progression after hypoxia and chemotherapy in hepatocellular carcinoma, Cancer Research. 2004, 64(15): 5496-5503. |
| Yang Z., Poon R.T.P., Luo Y., Cheung C.K.Y., Ho D.W.Y., Lo C.M. and Fan S.T., Up-regulation of vascualr endothelial growth factor (VEGF) in small-for-size liver grafts enhances macrophage activities through VEGF receptor 2-dependent pathway, Journal of Immunology. 2004, 173(4): 2507-2515. |
| Researcher : Yang ZF |
| List of Research Outputs |
| Researcher : Yau TO |
| List of Research Outputs |
| Yau T.O., Chan C.Y., Chan K.L., Lee M.F., Wong C.M., Fan S.T. and Ng I.O.L., Frequent down-regulation of HDPR1, a novel inhibitor of WNT/beta-catenin signaling, in hepatocellular carcinoma (Abstract), The 6th Annual Scientific Meeting, Centre for the Study of Liver Disease, The University of Hong Kong, Hong Kong, 8 January 2005. |
| Yau T.O., Chan C.Y., Chan K.L., Lee M.F., Wong C.M., Fan S.T. and Ng I.O.L., HDPR1, a novel inhibitor of WNT/b-catenin signaling, is down-regulated in hepatocellular carcinoma: involvement of promoter hypermethylation, AACR Special Conference in Cancer Research “Chromatin, chromosomes and cancer epigenetics”, Hawaii, USA, November 2004. |
| Yau T.O., Chan C.Y., Chan K.L., Lee M.F., Wong C.M., Fan S.T. and Ng I.O.L., HDPR1, a novel inhibitor of the WNT/beta-catenin signaling, is frequently downregulated in hepatocellular carcinoma: involvement of methylation-mediated gene silencing, Oncogene. 2005, 24(9): 1607-1614. |
| Yau T.O., Chan C.Y., Chan K.L., Lee M.F., Wong C.M., Fan S.T. and Ng I.O.L., Under-expression of HDPR1, a novel inhibitor of WNT/b-catenin signaling pathway, in hepatocellular carcinoma (Abstract), Asian Journal of Surgery. 2005, 28(Suppl 2): S84. |
| Yau T.O., Chan P.C.Y., Chan K.L., Lee M.F., Wong C.M., Fan S.T. and Ng I.O.L., Under-expression of HDPR1, a novel inhibitor of WNT/b-catenin signaling pathway, in hepatocellular carcinoma (Abstract), The 4th International Meeting on Hepatocellular Carcinoma: Eastern and Western Experiences, Hong Kong, 14-16 December 2004. |
| Researcher : Yeung C |
| List of Research Outputs |
| Lai A.T.Y., Lam C.M., Ng K.K.C., Yeung C., Ho W.L., Poon L.T. and Ng I.O.L., Hepatic actinomycosis presenting as a liver tumour: Case report and literature review, Asian Journal of Surgery. 2004, 27(4): 345-347. |
| Poon R.T.P., Fan S.T., Lo C.M., Liu C.L., Lam C.M., Yuen W.K., Yeung C. and Wong J., Improving perioperative outcome expands the role of hepatectomy in management of benign and malignant hepatobiliary diseases: analysis of 1222 consecutive patients from a prospective database, Annals of Surgery. 2004, 240(4): 698-708. |
| Researcher : Yeung YP |
| List of Research Outputs |
| Yeung Y.P., Natural history of untreated hepatocellular carcinoma, Thesis, Master of Medical Sciences, The University of Hong Kong. 2004. |
| Researcher : Yi X |
| List of Research Outputs |
| Luk J.M.C., Lam B.Y.H., Yi X., Peng J., Leng X. and Fan S.T., Applicability of proteomic biomarkers set to distinguish hepatocellular carcinoma from non-tumor and healthy liver tissues, 4th HUPO Annual Congress, Munich, Germany, 28 August - 1 September 2005. |
| Luk J.M.C., Lam B.K.Y., Yi X., Peng J., Leng X. and Fan S.T., Applicability of proteomic biomarkers set to distinguish hepatocellular carcinoma from non-tumor and healthy liver tissues, Molecular and cellular proteomics. 2005, 4(8) suppl. 13.55: S119. |
| Researcher : Yu WC |
| List of Research Outputs |
| Liu Y., Poon R.T.P., Hughes J., Feng X., Yu W.C. and Fan S.T., Chemokine receptors support infiltration of lymphocyte subpopulations in human hepatocellular carcinoma, Clinical Immunology. 2005, 114(2): 174-182. |
| Liu Y., Poon R.T.P., Hughes J., Li Q.Y., Yu W.C. and Fan S.T., Desensitization of T lymphocyte function by CXCR3 ligands in human hepatocellular carcinoma, World Journal of Gastroenterology. 2005, 11(2): 164-170. |
| Luk J.M.C., Lam B.K.Y., Lam C.T., Siu F.M., Ho D.W.Y., Yu W.C., Peng J.R., Che C.M., Leng X.S. and Fan S.T., Molecular classification of hepatocellular carcinoma by proteomic expression profiling (Abstract), The 6th Annual Scientific Meeting, Centre for the Study of Liver Disease, The University of Hong Kong, Hong Kong, 8 January 2005. |
| Ng K.K.C., Lam C.M., Poon R.T.P., Shek T.W.H., Yu W.C., To J.Y.T., Wo Y.H., Lau C.P.Y., Tang T.C.M., Ho D.W.Y. and Fan S.T., Porcine liver: morphological characteristics and cell viability at experimental radiofrequency ablation with internally cooled electrodes, Radiology. 2005, 235(2): 478-486. |
| Yang Z., Ho D.W.Y., Lam C.T., Luk J.M.C., Lum C.T., Yu W.C., Poon R.T.P. and Fan S.T., Identification of brain-derived neurotrophic factor (BDNF) as a potential therapeutic target in hepatocellular carcinoma (Abstract), The 4th International Meeting on Hepatocellular Carcinoma: Eastern and Western Experiences, Hong Kong, 14-16 December 2004. |
| Yang Z., Ho D.W.Y., Lam C.T., Luk J.M.C., Yu W.C., Lo C.M., Poon R.T.P. and Fan S.T., Identification of brain-derived neurotrophic factor (BDNF) in hepatocellular carcinoma - from animal study to clinical management (Abstract), The 6th Annual Scientific Meeting, Centre for the Study of Liver Disease, The University of Hong Kong, Hong Kong, 8 January 2005. |
| Yang Z., Ho D.W.Y., Lam C.T., Luk J.M.C., Lum C.T., Yu W.C., Poon R.T.P. and Fan S.T., Identification of brain-derived neurotrophic factor as a novel functional protein in hepatocellular carcinoma, Cancer Research. 2005, 65(1): 219-225. |
| Researcher : Yuan Z |
| List of Research Outputs |
| Tian L., Yuan Z., Cai Q., Lui Y., Thompson P., Tam P.K.H. and Lamb J.R., Combined treatment with cyclosporin A and rosiglitazone prevents chronic allograft rejection, 9th Basic Science Symposium of the Transplantation Society, LaBaule, France, 19-22 June 2005. |
| Researcher : Yuen HF |
| List of Research Outputs |
| Lam C.M., Ng K.K.C., Poon R.T.P., Yuen H.F. and Fan S.T., Thoracoscopic RFA (Invited Lecture), The 4th International Meeting on Hepatocellular Carcinoma: Eastern and Western Experiences, Hong Kong, 14-16 December 2004. |
| Researcher : Yuen PW |
| Project Title: | The identification of proteomic tumor marker of upper aerodigestive tract squamous cell carcinoma |
| Investigator(s): | Yuen PW, He Q, Chiu J |
| Department: | Surgery |
| Source(s) of Funding: | Merit Award for RGC CERG Funded Projects |
| Start Date: | 09/2003 |
| Abstract: |
| To identify the proteomic tumor markers of UADTSCC that are differentially expressed in both UADTSCC primary tumor and sera of patients. These differentially expressed proteins can provide information on the molecular mechanism of carcinogenesis of UADTSCC and may also be used clinically for screening of cancer and monitoring recurrence after treatment. |
| Project Title: | The identification of proteomic tumor marker of upper aerodigestive tract squamous cell carcinoma |
| Investigator(s): | Yuen PW, He Q, Chiu J |
| Department: | Surgery |
| Source(s) of Funding: | Competitive Earmarked Research Grants (CERG) |
| Start Date: | 09/2003 |
| Abstract: |
| To identify the proteomic tumor markers of UADTSCC that are differentially expressed in both UADTSCC primary tumor and sera of patients. These differentially expressed proteins can provide information on the molecular mechanism of carcinogenesis of UADTSCC and may also be used clinically for screening of cancer and monitoring recurrence after treatment. |
| Project Title: | The identification of a panel of methylated gene promoters as tumor markers of nasopharyngeal carcinoma |
| Investigator(s): | Yuen PW |
| Department: | Surgery |
| Source(s) of Funding: | Small Project Funding |
| Start Date: | 11/2003 |
| Abstract: |
| To identify a panel of methylated genes as tumor marker of nasopharyngeal carcinoma (NPC). |
| Project Title: | The evaluation of the clinical application of hypermethylated promoter DNA as tumor marker of nasopharyngeal carcinoma |
| Investigator(s): | Yuen PW, Kwong DLW |
| Department: | Surgery |
| Source(s) of Funding: | Competitive Earmarked Research Grants (CERG) |
| Start Date: | 01/2005 |
| Abstract: |
| To identify the genes that are frequently methylated in NPC tumor and can be used as tumor marker in body fluids of blood, nasopharyngeal swab and throat rinsing fluid for the screening of primary NPC and residual NPC after treatment. |
| Project Title: | The evaluation of the clinical application of hypermethylated DNA as tumor marker in body fluids for screening of primary and recurrent nasopharyngeal carcinoma |
| Investigator(s): | Yuen PW, Sham JST, Kwong DLW, Wei WI |
| Department: | Surgery |
| Source(s) of Funding: | Michael Kadoorie Cancer Genetics Research Fund |
| Start Date: | 01/2005 |
| Abstract: |
| To identify genes that are specifically and frequently methylated in NPC; to evaluate the sensitivity and specificity of screening primary and recurrent NPC in body fluids of peripheral blood, nasopharyngeal swab and throat rinsing fluid using methylated DNA as tumor marker. |
| Project Title: | The evaluation of the clinical application of hypermethylated promoter DNA as tumor marker of nasopharyngeal carcinoma |
| Investigator(s): | Yuen PW |
| Department: | Surgery |
| Source(s) of Funding: | Merit Award for RGC CERG Funded Projects |
| Start Date: | 01/2005 |
| Abstract: |
| Refer to hard copy |
| List of Research Outputs |
| Au W.Y., Chan C., Pang A., Lie A.K.W., Liang R.H.S., Yuen P.W., Shek T.W.H., Kwong Y.L. and Pang A.W.K., Nonhematologic malignancies after allogeneic hematopoietic stem cell transplantation: incidence and molecular monitoring, Bone Marrow Transplantation. 2004, 34: 981-985. |
| Au W.Y., Lie A.K.W., Liang R.H.S., Yuen P.W., Shek T.W.H. and Kwong Y.L., Secondary non-hematologic malignancies after allogeneic stem cell transplantation : incidence and molecular monitoring, 10th Congress of the International Society of hematology, Asian Pacific Division, Nagoya, Japan. Nagoya, Japan, 2004, 110. |
| Ho W.K., Ng W.M., Wei W.I. and Yuen P.W., Ortner’s Syndrome: A radiological diagnosis. Poster presentation, 12th Annual Scientific Meeting, Hong Kong College of Radiologists. . Hong Kong, 2004. |
| Szeto C.H., Shek T.W.H., Lie A.K.W., Au W.Y., Yuen P.W. and Kwong Y.L., Squamous cell carcinoma of the tongue complicating chronic oral mucosal graft-versus-host disease after allogeneic hematopoietic stem cell transplantation, American Journal of Hematology. 2004, 77(2): 200-202. |
| Wei W.I., Yuen P.W., Ng W.M., Ho W.K., Kwong D.L.W. and Sham J.S.T., Quantitative analysis of plasma cell-free epstein-barr virus DNA in nasopharyngeal carcinoma after salvage nasopharyngectomy: a prospective study, Head & Neck. 2004, 26: 878-883. |
| Wong T.S., Kwong D.L.W., Sham J.S.T., Wei W.I., Kwong Y.L. and Yuen P.W., Elevation of plasma osteopontin level in patients with undifferentiated nasopharyngeal carcinoma, European Journal of surgical Oncology. 2005, 31: 555-558. |
| Yuen P.W., Cancer of the tongue, Operative Techniques in Otolaryngology. 2004, 15: 234-238. |
| Yuen P.W., Craniofacial resection for skull base tumour: a review of 10 years' experience and a case stdy of cavernous sinus exenteration, 11th Annual Scientific Meting, the Hong Kong Neurosurgical Society, Hong Kong, 3-4 December 2004. |
| Yuen P.W., Endoscopic assisted cranionasal resection of olfactory neuroblastoma, Head and Neck 2005. 2005, 27(6): 488-493. |
| Yuen P.W., Member of Editorial Board (1996 - present), Korean Journal of Rhinology. 2005. |
| Yuen P.W., Member of Editorial Board (2001 - present), Hong Kong Medical Journal. 2005. |
| Yuen P.W., Methylation status of Reprimo in head and neck carcinomas, Inernational Journal of Cancer 2005. 2005, 117(4): 697. |
| Yuen P.W., Ultrasonic glossectomy-simple and bloodless, Head & Neck. 2005, 27: 690-695. |
| Researcher : Yuen WK |
| List of Research Outputs |
| Chok K.S.H., Yuen W.K., Lau H., Lee F.C.W. and Fan S.T., Outpatient laparoscopic cholecystectomy in Hong Kong Chinese - an outcome analysis, Asian Journal of Surgery. 2004, 27(4): 313-316. |
| Chok S.H., Yuen W.K., Lau H., Lee F.C.W. and Fan S.T., Outpatient laparoscopic cholecystectomy - a review of 135 consecuttive patients (Abstract), Surgical Practice. 2005, 9 (Supplement): S8. |
| Chok S.H., Yuen W.K., Lau H. and Lee F.C.W., Outpatient laparoscopic cholecystectomy: a reivew of 135 consecutive patients, Endoscopic & Laparoscopic Surgeons of Asia Regional Meeting and 4th World Congress of Gasless Laparoscopic Surgery, Bali, Indonesia, 26-29 September 2004. |
| Lau H., Patil N.G. and Yuen W.K., Outcomes of laparoscopic incisional hernia repair: A prospective evaluation, Surgical Practice. 2005, 9: 13-17. |
| Poon R.T.P., Fan S.T., Lo C.M., Liu C.L., Lam C.M., Yuen W.K., Yeung C. and Wong J., Improving perioperative outcome expands the role of hepatectomy in management of benign and malignant hepatobiliary diseases: analysis of 1222 consecutive patients from a prospective database, Annals of Surgery. 2004, 240(4): 698-708. |
| Researcher : Zhang H |
| List of Research Outputs |
| Yi C., Li Z., Yuan K., Qu X., Chen J., Wang G., Zhang H., Luo H., Zhu L., Jiang P., Chen L., Shen Y., Luo M., Zuo G., Hu J., Duan D., Nie Y., Shi X., Wang W., Han Y., Li T., Liu Y., Ding M., Deng H. and Xu X., Small molecules blocking the entry of SARS-Co V into host, Journal of Virology. 2004, 78(2)): 11334-11339. |
| Researcher : Zhao Y |
| List of Research Outputs |
| Man K., Ng T.P., Lee K.W., Lo C.M., Sun K.W., Li X., Zhao Y., Ho J.W.Y. and Fan S.T., FTY720 attenuates hepatic ischemia-reperfusion injury in normal and cirrhotic livers, American Journal of Transplantation. 2005, 5(1): 40-49. |
| Man K., Ng T.P., Lo C.M., Sun K.W., Zhao Y., Ho J.W.Y., Lee K.W. and Fan S.T., Hepatic I/R injury on small liver remnant promotes liver tumor growth and metastasis - activation of cell invasion and migration pathways (Abstract), The 20th International Congress of the Transplantation Society, Vienna, Austria, 5-10 September 2004. |
| Man K., Xu A., Xu A., Zhao Y., Lo C.M., Ng T.P., Sun K.W. and Fan S.T., Rescue of small-for-size fatty liver grafts injury by FTY720 and adiponectin combination therapy (Abstract), The 20th International Congress of the Transplantation Society, Vienna, Austria, 5-10 September 2004. |
| Researcher : Zhu L |
| List of Research Outputs |
| Yi C., Li Z., Yuan K., Qu X., Chen J., Wang G., Zhang H., Luo H., Zhu L., Jiang P., Chen L., Shen Y., Luo M., Zuo G., Hu J., Duan D., Nie Y., Shi X., Wang W., Han Y., Li T., Liu Y., Ding M., Deng H. and Xu X., Small molecules blocking the entry of SARS-Co V into host, Journal of Virology. 2004, 78(2)): 11334-11339. |
| Zhu L., Determination of predictive markers related to micro-metastasis in breast cancer patients, Thesis, Master of Philosophy, The University of Hong Kong. 2004. |
| Zhu L., Chow L.W.C., Loo T.Y., Guan X.Y. and Toi M., Her2/neu expression predicts the response to antiaromatase neoadjuvant therapy in primary breast cancer: subgroup analysis from celecoxib antiaromatase neoadjuvant trial, Clinic Cancer Research. 2004, 10(14): 4639-4644. |
| Zhu L., Lam C.K. and Chow L.W.C., Sentinel lymph node biopsy or detection of micrometastasis in bone marrow: which might be an alternative to axillary lymph node dissection in breast cancer patients?, Asian Journal of Surgery. 2004, 27: 279-283. |
| Researcher : Zhu L |
| List of Research Outputs |
| Yi C., Li Z., Yuan K., Qu X., Chen J., Wang G., Zhang H., Luo H., Zhu L., Jiang P., Chen L., Shen Y., Luo M., Zuo G., Hu J., Duan D., Nie Y., Shi X., Wang W., Han Y., Li T., Liu Y., Ding M., Deng H. and Xu X., Small molecules blocking the entry of SARS-Co V into host, Journal of Virology. 2004, 78(2)): 11334-11339. |
| Zhu L., Determination of predictive markers related to micro-metastasis in breast cancer patients, Thesis, Master of Philosophy, The University of Hong Kong. 2004. |
| Zhu L., Chow L.W.C., Loo T.Y., Guan X.Y. and Toi M., Her2/neu expression predicts the response to antiaromatase neoadjuvant therapy in primary breast cancer: subgroup analysis from celecoxib antiaromatase neoadjuvant trial, Clinic Cancer Research. 2004, 10(14): 4639-4644. |
| Zhu L., Lam C.K. and Chow L.W.C., Sentinel lymph node biopsy or detection of micrometastasis in bone marrow: which might be an alternative to axillary lymph node dissection in breast cancer patients?, Asian Journal of Surgery. 2004, 27: 279-283. |
| Researcher : Zhu R |
| List of Research Outputs |
| He Q., Zhu R., Ren Y., Tam P.K.H. and Chiu J., Serological protein profiling of neuroblastoma by proteinchip SELDI-TOF technology, Journal of Cellular Biochemistry. 2005, 95: 165-172. |